NOD Mice-Good Model for T1D but Not Without Limitations.

abstract：:Although emerging evidence links mesenchymal stem cells (MSCs) with cancer metastasis, the underlying mechanisms are poorly understood. In the present study, we found that human umbilical cord-derived MSCs (UC-MSCs) promoted MCF-7 cell migration in vitro and metastasis in vivo. To explore the mechanisms, the character...

journal_title：Cell transplantation

authors： Ma F,Chen D,Chen F,Chi Y,Han Z,Feng X,Li X,Han Z

更新日期：2015-01-01 00:00:00

abstract：:There are conflicting reports on the survival and immune reaction to allografts and xenografts of cultured skin substitutes (CSS). In this study, we investigated the allogeneic and xenogeneic responses to CSS of human keratinocytes and genetically engineered CSS expressing keratinocyte growth factor (KGF) that forms a...

journal_title：Cell transplantation

authors： Erdag G,Morgan JR

更新日期：2004-01-01 00:00:00

abstract：:In diabetic patients cardiovascular morbidity and mortality is still a major problem. Our aim was to study the effect of kidney-pancreas transplantation on survival, cardiovascular events, and causes of death in diabetic type 1 uremic patients. Three hundred and thirty-three uremic IDDM patients were enrolled in our w...

journal_title：Cell transplantation

authors： La Rocca E,Fiorina P,Astorri E,Rossetti C,Lucignani G,Fazio F,Giudici D,Castoldi R,Bianchi G,Di Carlo V,Pozza G,Secchi A

更新日期：2000-11-01 00:00:00

abstract：:Human skin contains keratinocytes in the epidermis. Such cells share their ectodermal origin with the central nervous system (CNS). Recent studies have demonstrated that terminally differentiated somatic cells can adopt a pluripotent state, or can directly convert its phenotype to neurons, after ectopic expression of ...

journal_title：Cell transplantation

authors： Tenorio-Mina A,Cortés D,Esquivel-Estudillo J,López-Ornelas A,Cabrera-Wrooman A,Lara-Rodarte R,Escobedo-Avila I,Vargas-Romero F,Toledo-Hernández D,Estudillo E,Acevedo-Fernández JJ,Tapia JS,Velasco I

更新日期：2021-01-01 00:00:00

abstract：:As a putative marker of cerebral small vessel disease, cerebral microbleeds (CMBs) have been associated with vascular cognitive impairment. Both iron accumulation and amyloid protein precursor (APP) dysregulation are recognized as pathological hallmarks underlying the progression of CMBs, but their cross-talk is not y...

journal_title：Cell transplantation

authors： Gong L,Tian X,Zhou J,Dong Q,Tan Y,Lu Y,Wu J,Zhao Y,Liu X

更新日期：2019-08-01 00:00:00

abstract：:The human neuronal cell-1 (HCN-1) line has recently been established. Under favorable conditions, these cells differentiate into mature neuronal phenotypes. Here we report on further characterization of these cells. Cultured HCN-1 cells express fibronectin immunoreactivity and grow well on fibronectin substrate but do...

journal_title：Cell transplantation

authors： Poltorak M,Isono M,Freed WJ,Ronnett GV,Snyder SH

更新日期：1992-01-01 00:00:00

abstract：:Facioscapulohumeral muscular dystrophy (FSHD) is the third most frequent inherited myopathy. We previously demonstrated that mesoangioblasts can be efficiently isolated from FSHD muscles, although their differentiation ability into skeletal muscle was variably impaired. This correlates with overall disease severity a...

journal_title：Cell transplantation

authors： Morosetti R,Gidaro T,Broccolini A,Gliubizzi C,Sancricca C,Tonali PA,Ricci E,Mirabella M

更新日期：2011-01-01 00:00:00

abstract：:Hepatocyte transplantation is a promising therapy for acute liver failure in humans. Recently, we succeeded in inducing various acute and chronic liver failures in nude mice. Engraftment of transplanted xenogeneic rat hepatocytes, visualized in the host liver by anti-MHC class I immunohistochemistry, revealed that liv...

journal_title：Cell transplantation

authors： Vidal I,Blanchard N,Alexandre E,Gandillet A,Chenard-Neu MP,Staedtler F,Schumacher M,Bachellier P,Jaeck D,Firat H,Heyd B,Richert L

更新日期：2008-01-01 00:00:00

abstract：:Adequate regulation of glucose levels by a microencapsulated pancreatic islet graft requires a minute-to-minute regulation of blood glucose. To design such a transplant, it is mandatory to have sufficient insight in factors influencing the kinetics of insulin secretion by encapsulated islets. The present study investi...

journal_title：Cell transplantation

authors： de Haan BJ,Faas MM,de Vos P

更新日期：2003-01-01 00:00:00

abstract：REGISTRATION NUMBER OF CLINICAL TRIALS:ChiCTR1900021317. ...

journal_title：Cell transplantation

authors： He M,Guo X,Li T,Jiang X,Chen Y,Yuan Y,Chen B,Yang G,Fan Y,Liang Z,Armstrong DG,Deng W

更新日期：2020-01-01 00:00:00

abstract：:Pluripotent stem cells, including human embryonic stem cells and induced pluripotent stem cells, have generated much excitement about their prospects for use in cell transplantation therapies. This is largely attributable to their virtually unlimited growth potential, their ability to be precisely genetically altered ...

journal_title：Cell transplantation

authors： Robinson AJ,Zhao G,Rathjen J,Rathjen PD,Hutchinson RG,Eyre HJ,Hemsley KM,Hopwood JJ

更新日期：2010-01-01 00:00:00

abstract：:Neuronal progenitor cells (NPCs) derived from human embryonic stem cells (hESCs) are an excellent cell source for transplantation therapy due to their availability and ethical acceptability. However, the traditional method of expansion and differentiation of hESCs into NPCs in monolayer cultures requires a long time, ...

journal_title：Cell transplantation

authors： Qiu L,Lim YM,Chen AK,Reuveny S,Oh SK,Tan EK,Zeng L

更新日期：2016-01-01 00:00:00

abstract：:We developed a reliable and quantitative method for measuring the dynamic process of unidirectional two-dimensional (2-D) tissue formation of endothelial cells (ECs) in vitro. The culturing of bovine ECs in an assembled culture chamber provided a square monolayered cell sheet with a linear margin when disassembled at ...

journal_title：Cell transplantation

authors： Niu S,Matsuda T

更新日期：1992-01-01 00:00:00

abstract：:It is currently said that CO has anti-inflammatory and antiapoptosis effects and it has attracted attention as a medical gas. We used CO for rat hearts and conducted a preservation experiment. We isolated rat hearts, placed them into a specially made chamber, filled the chamber with a gas mixture of PCO (4,000 hPa) a...

journal_title：Cell transplantation

authors： Hatayama N,Naito M,Hirai S,Yoshida Y,Kojima T,Seki K,Li XK,Itoh M

更新日期：2012-01-01 00:00:00

abstract：:Nerve growth factor (NGF) exerts both trophic (cell survival) and tropic (axonal growth-promoting) effects on several neuronal populations. In particular, its robust ability to prevent lesion-induced and spontaneous age-related basal forebrain cholinergic neuronal degeneration, and to promote mnemonic recovery, has su...

journal_title：Cell transplantation

authors： Tuszynski MH

更新日期：2000-09-01 00:00:00

abstract：:We investigated the effects of transplantation of CXCR4-overexpressing adipose tissue-derived stem cells (ADSCs) into a mouse diabetic hindlimb ischemia model on homing and engraftment as early as 48 h after transplant. CXCR4-overexpressing ADSCs were intramuscularly or intravenously injected into diabetic mice with h...

journal_title：Cell transplantation

authors： Kim M,Kim DI,Kim EK,Kim CW

更新日期：2017-02-16 00:00:00

abstract：:This study examined how the difference in pore size of porous scaffolds affected the in vitro chondrogenic differentiation of seeded adipose stem cells (ASCs) and the in vivo cartilage repair of ASC/scaffold construct. ASCs were isolated from 18 rabbits and seeded in a porous poly (ε-caprolactone) (PCL) scaffold with ...

journal_title：Cell transplantation

authors： Im GI,Ko JY,Lee JH

更新日期：2012-01-01 00:00:00

abstract：:Persistent corneal wounds result from numerous eye disorders, and to date, available treatments often fail to accelerate reepithelialization, the key initial step in wound healing. To speed reepithelialization, we explored a cell-transfer transplant method utilizing polydimethylsiloxane (PDMS) contact lenses to delive...

journal_title：Cell transplantation

authors： Pino CJ,Haselton FR,Chang MS

更新日期：2005-01-01 00:00:00

abstract：:Cord blood is an attractive cell source in regenerative medicine and represents an alternative to bone marrow. The aim of this study was to investigate whether human umbilical cord blood mononuclear (HUCBM) cells might be valuable in hepatic regenerative medicine. HUCBM cells differentiated in vitro into hepatocytes, ...

journal_title：Cell transplantation

authors： Alvarez-Mercado AI,Sáez-Lara MJ,García-Mediavilla MV,Sánchez-Campos S,Abadía F,Cabello-Donayre M,Gil A,González-Gallego J,Fontana L

更新日期：2008-01-01 00:00:00

abstract：:Liver fibrosis is characterized by excessive accumulation of extracellular matrix components in the liver parenchyma that distorts the normal architecture and hepatic function. Progressive fibrosis could end in the advanced stage known as cirrhosis, resulting in the need to resort to liver transplantation. Amniotic me...

journal_title：Cell transplantation

authors： SantAnna LB,Hage R,Cardoso MA,Arisawa EA,Cruz MM,Parolini O,Cargnoni A,SantAnna N

更新日期：2016-12-13 00:00:00

abstract：:Exenatide is an analog of the incretin hormone glucagon-like peptide (GLP-1) that is used for the treatment of T2D for their metabolic effects. In addition to its insulinotropic effects, exenatide increases functional islet mass and improves their survival. Improved outcomes have been reported in recent clinical isle...

journal_title：Cell transplantation

authors： Cechin SR,Pérez-Álvarez I,Fenjves E,Molano RD,Pileggi A,Berggren PO,Ricordi C,Pastori RL

更新日期：2012-01-01 00:00:00

abstract：:The prevalence of HIV-associated neurocognitive disorders (HAND) remains high despite combination antiretroviral therapy (cART). There is evidence that neural stem cells (NSCs) can migrate to sites of brain injury such as those caused by inflammation and oxidative stress, which are pathological features of HAND. Thus,...

journal_title：Cell transplantation

authors： Jin J,Grimmig B,Izzo J,Brown LAM,Hudson C,Smith AJ,Tan J,Bickford PC,Giunta B

更新日期：2016-11-01 00:00:00

abstract：:Biological pacing has been proposed as a physiologic counterpart to electronic pacing, and the sinoatrial node (SAN) is the general standard for biological pacemakers. We tested the expression of SAN pacemaker cell activity when implanted autologously in the right ventricle (RV). We induced complete heart block and i...

journal_title：Cell transplantation

authors： Zhang H,Lau DH,Shlapakova IN,Zhao X,Danilo P,Robinson RB,Cohen IS,Qu D,Xu Z,Rosen MR

更新日期：2011-01-01 00:00:00

abstract：:Spinal cord injury (SCI) causes loss of neural functions below the level of the lesion due to interruption of spinal pathways and secondary neurodegenerative processes. The transplant of neural stem cells (NSCs) is a promising approach for the repair of SCI. Reprogramming of adult somatic cells into induced pluripoten...

journal_title：Cell transplantation

authors： López-Serrano C,Torres-Espín A,Hernández J,Alvarez-Palomo AB,Requena J,Gasull X,Edel MJ,Navarro X

更新日期：2016-10-01 00:00:00

abstract：:Endostatin (ES) is a potent inhibitor of angiogenesis and tumor growth. Continuous ES delivery of ES improves the efficacy and potency of the antitumoral therapy. The TheraCyte system is a polytetrafluoroethylene (PTFE) semipermeable membrane macroencapsulation system for implantation of genetically engineered cells s...

journal_title：Cell transplantation

authors： Malavasi NV,Rodrigues DB,Chammas R,Chura-Chambi RM,Barbuto JA,Balduino K,Nonogaki S,Morganti L

更新日期：2010-01-01 00:00:00

abstract：:This study aimed to explore the characteristics of TGFBR1-epidermal growth factor receptor (EGFR)-CTNNB1-CDH1 axis in regulating the invasion and migration in lung cancer. Using the small interfering RNA technology, EGFR was silenced in H2170 and H1299 cells. Then, the colony formation, migration, and invasion abiliti...

journal_title：Cell transplantation

authors： Liu R,Zhang Y,Ding Y,Zhang S,Pan L

更新日期：2020-01-01 00:00:00

abstract：:The present study was designed to evaluate the use of collagen gel loaded with human retinal pigment epithelium (ARPE19) in cellular transfer and to assess its viability within the gel. Collagen solution was prepared by dissolving calfskin in hydrochloric acid to make a final concentration of 2.0 mg/ml and this was mi...

journal_title：Cell transplantation

authors： Yeung CK,Chiang SW,Chan KP,Lam DS,Pang CP

更新日期：2004-01-01 00:00:00

abstract：:Gammopathies, multiple myeloma, and amyloidosis are plasma dyscrasias characterized by clonal proliferation and immunoglobulin overproduction. Renal impairment is the most common and serious complication with an incidence of 20-30% patients at the diagnosis. Kidney transplant has not been considered feasible in the pr...

journal_title：Cell transplantation

authors： Baraldi O,Grandinetti V,Donati G,Comai G,Battaglino G,Cuna V,Capelli I,Sala E,La Manna G

更新日期：2016-01-01 00:00:00

abstract：:A newly developed immunosuppressant, FTY720, has a unique mechanism that is quite different from those of conventional immunosuppressants, and is presumed to be mediated through decreases in the number of peripheral lymphocytes, especially helper T cells. This study was performed to ascertain whether this innovative d...

journal_title：Cell transplantation

authors： Yamasaki T,Inoue K,Hayashi H,Gu Y,Setoyama H,Ida J,Cui W,Kawakami Y,Kogire M,Imamura M

更新日期：1998-07-01 00:00:00

abstract：:In order to fully characterize and determine the therapeutic potential of adult neural progenitor cells (NPCs), it is important to be able to isolate and study NPCs from animals such as rats, in which there are existing models of brain injury and disease. The focus of this study was to characterize the cultivation, di...

journal_title：Cell transplantation

authors： Chen K,Hughes SM,Connor B

更新日期：2007-01-01 00:00:00