Abstract:
:The recently known coronavirus, SARS-CoV-2, has turn into the greatest global health challenge, affecting a large number of societies. The lack of specific treatment and gold-standard diagnostic system has made the situation more complicated. Efforts have led to production of several diagnostic kits that are associated with limitations such as inadequate sensitivity and accuracy. Aptamers as multipotent biological probes could be promising candidates to design sensitive and specific biosensors. Although few studies have introduced specific aptamer types of coronavirus, they may help us select the best approach to obtain specific aptamers for this virus. On the other hand, some of already-introduced aptamers have shown the inhibitory effects on coronavirus that could be applied as therapeutics. The present study has provided a systematic overview on use of aptamer-based biosensors and drugs to diagnose and treat coronavirus.
journal_name
Mol Cell Probesjournal_title
Molecular and cellular probesauthors
Torabi R,Ranjbar R,Halaji M,Heiat Mdoi
10.1016/j.mcp.2020.101636subject
Has Abstractpub_date
2020-10-01 00:00:00pages
101636eissn
0890-8508issn
1096-1194pii
S0890-8508(20)30264-4journal_volume
53pub_type
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