Abstract:
OBJECTIVE:To evaluate the antimicrobial activity of Momordica charantia extracts on reference strains and microorganisms isolated from clinical specimens. METHOD:Petroleum ether and methanolic crude extracts of fruits and leaves of the plant were evaluated for antimicrobial activity using the disk diffusion method on four reference microorganisms (Pseudomonas aeruginosa, Escherichia coli, Candida albicans and Staphylococcus aureus; and four clinical strains of Klebsiella pneumoniae, Proteus vulgaris, Salmonella typhi and Cryptococcus neoformans. RESULT:Antimicrobial activity was observed against all the tested microorganisms with exception to P. mirabilis and C. neoformans. Methanolic crude extracts exhibited relatively broader antimicrobial spectrum of activity than petroleum ether extracts with the as lower concentration as 0.075mg/µl. Methanolic fruit crude extract displayed the broadest antimicrobial spectrum by inhibiting majority (75%) of the tested microorganisms. Neither was there synergistic nor addition effect upon mixing leaf and fruit extracts of equal concentrations derived from the same solvent. CONCLUSION:Extracts of M.charantia demonstrated antimicrobial activity on tested microorganisms except on Proteus mirabilis and Cryptococcus neoformans. Fruit extracts showed higher antimicrobial activity than leaf extract. Further studies are recommended that will involve various parts of the plant, select different fractions of extracts and purify the active antimicrobial components.
journal_name
Afr Health Scijournal_title
African health sciencesauthors
Mwambete KDsubject
Has Abstractpub_date
2009-03-01 00:00:00pages
34-9issue
1eissn
1680-6905issn
1729-0503journal_volume
9pub_type
杂志文章abstract::We report an inbred Tunisian family, in which the proband manifested signs of hypohidrotic ectodermal dysplasia, subtotal amelia, scoliosis and left renal agenesis. Two other family members had the full clinical criteria of hypohidrotic ectodermal dysplasia, characterized by deficient sweat glands, hypodontia, hypopla...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.5555/afhs.2005.5.3.270
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVE:The study was performed to investigate the association of interleukin 17 (IL 17) or angiotensin II (Ang II) with refractory hypertension risk in hemodialysis patients. METHODS:Ninety hemodialysis patients were enrolled into this study, and those with hypertension were divided into two groups. The Easy-to-Con...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v16i3.17
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abstract:Background:The staphylococci have increasingly been associated with infections worldwide and anti-microbial resistance has made these versatile pathogens more recalcitrant in the hospital setting. Objectives:This study sought to investigate the occurrence and distribution of Staphylococcus species as well as determine...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v17i4.7
更新日期:2017-12-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
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更新日期:2019-03-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章,评审
doi:
更新日期:2003-12-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v20i2.27
更新日期:2020-06-01 00:00:00
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pub_type: 杂志文章
doi:10.4314/ahs.v17i1.11
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journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v18i2.8
更新日期:2018-06-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
doi:
更新日期:2009-09-01 00:00:00
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pub_type: 杂志文章
doi:10.4314/ahs.v16i4.4
更新日期:2016-12-01 00:00:00
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pub_type: 杂志文章
doi:10.4314/ahs.v15i3.16
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pub_type: 杂志文章,meta分析
doi:10.4314/ahs.v15i2.28
更新日期:2015-06-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:African health sciences
pub_type: 杂志文章
doi:
更新日期:2010-12-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v16i2.13
更新日期:2016-06-01 00:00:00
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pub_type: 杂志文章
doi:10.4314/ahs.v19i3.33
更新日期:2019-09-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,随机对照试验
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更新日期:2018-12-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v20i2.7
更新日期:2020-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-03-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章,评审
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更新日期:2013-09-01 00:00:00
abstract:Background:Malnutrition is an important clinical outcome amongst HIV patients in developing countries and in Uganda, there is scarcity of information on its prevalence and risk factors amongst HIV adult patients. Methods:A cross-sectional study amongst 253 HIV patients in Bushenyi district assessed their nutritional s...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v20i1.17
更新日期:2020-03-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v20i3.47
更新日期:2020-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2014-09-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
doi:
更新日期:2011-09-01 00:00:00