Echocardiographic pattern and severity of valve dysfunction in children with rheumatic heart disease seen at Uganda Heart Institute, Mulago hospital.

Abstract:

BACKGROUND:Rheumatic heart disease (RHD) is the commonest acquired heart disease in children worldwide but in Uganda, data is scarce regarding its morbidity and mortality. The disease has a progressive course and patients usually require valve repair/replacement in the future. OBJECTIVES:To describe the frequency of echocardiographic valvular dysfunction in children with RHD To explore the relationship between the severity of valvular dysfunction by the age and sex of the children with RHD. METHODS:Echocardiographic findings of children ≤15 years with RHD seen at Uganda Heart Institute from January 2007 to December 2011 were retrospectively analyzed. RESULTS:376 children had a diagnosis of RHD. The mean age of the children was 11.0 ± 2.7 years and 216 (57.4%) were females. Mitral regurgitation was the commonest lesion seen in 98.9% (severe in 73.1%) of the children. Aortic regurgitation (AR) was found in 51.3% (severe in 7.2%), mitral stenosis (MS) was found in 10.6% (severe in 5.9%), tricuspid regurgitation was found in 86.7% (severe in 8.2%) while aortic stenosis was seen in 1.3% (severe in 0.3%). Severe AR was less common in females (OR=0.32, 95%CI 0.13-0.78) and children with MS were older than those without MS (12.7 ± 2.0 Vs. 10.7 ± 2.7 years, p<0.00). CONCLUSIONS:Mitral valve dysfunction was found in almost all the cases of RHD and majority of the children had severe valve disease at the time of their first presentations. Children with MS were predominantly above 10 years and severe AR was more common in males.

journal_name

Afr Health Sci

journal_title

African health sciences

authors

Lubega S,Aliku T,Lwabi P

doi

10.4314/ahs.v14i3.17

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

617-25

issue

3

eissn

1680-6905

issn

1729-0503

pii

jAFHS.v14.i3.pg617

journal_volume

14

pub_type

杂志文章
  • An audit of surgical site infection following open prostatectomy in a Nigerian Teaching Hospital.

    abstract:Background:Surgical site infections (SSI) are a potential cause of morbidity and increased cost of care after operations such as open prostatectomy. Objective:To audit the occurrence of SSI after open prostatectomy at the Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile-Ife, Nigeria. Methods:A revi...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v19i2.30

    authors: Salako AA,Badmus TA,Onyia CU,David RA,Adejare IE,Lawal AO,Onyeze CI,Ndegbu CU

    更新日期:2019-06-01 00:00:00

  • Neurosyphilis masquerading as hemiparesis and Jacksonian epilepsy in an HIV positive patient: a case report.

    abstract:BACKGROUND:Neurosyphilis is a common but often missed disease worldwide, mainly because it has many manifestations making its diagnosis difficult. It is often missed among HIV patients as the search for other co-infections such as toxoplasmosis often overshadows its consideration. OBJECTIVES:To describe one of our cas...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Kyebambe PS

    更新日期:2010-06-01 00:00:00

  • Seroprevalence of parvovirus B19 in blood donors: the risks and challenges of blood transfusion in Zambia in the era of HIV/AIDS at the Kitwe Central Hospital, blood bank.

    abstract:Background:Human Parvovirus (B19V) is a small, single-stranded, non-enveloped DNA virus which is pathogenic to humans causing a wide array of clinical complications which include erythema infectiosum, aplastic crisis and hydrops foetalis. It is generally harmless in healthy individuals but may be life threatening in im...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v18i3.5

    authors: Chirambo-Kalolekesha M,Kaile T,Mwaba F,Daka V,Simakando M,Kowa S

    更新日期:2018-09-01 00:00:00

  • Endometriosis of the appendix.

    abstract::Endometriosis is a well known cause of infertility. Endometriosis of the appendix is a very rare condition. To highlight this rare entity, we are reporting a case of a young lady who was admitted with recurrent attacks of lower abdominal pain associated with primary infertility. Preoperative diagnosis was acute append...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Al Oulaqi NS,Hefny AF,Joshi S,Salim K,Abu-Zidan FM

    更新日期:2008-09-01 00:00:00

  • The in vitro antimicrobial activity of fruit and leaf crude extracts of Momordica charantia: a Tanzania medicinal plant.

    abstract:OBJECTIVE:To evaluate the antimicrobial activity of Momordica charantia extracts on reference strains and microorganisms isolated from clinical specimens. METHOD:Petroleum ether and methanolic crude extracts of fruits and leaves of the plant were evaluated for antimicrobial activity using the disk diffusion method on ...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Mwambete KD

    更新日期:2009-03-01 00:00:00

  • Utilization of health care services in rural and urban areas: a determinant factor in planning and managing health care delivery systems.

    abstract:BACKGROUND:Disparities in use of healthcare services between rural and urban areas have been empirically attributed to several factors. This study explores the existence of this disparity and its implication for planning and managing healthcare delivery systems. OBJECTIVES:The objectives determine the relative importa...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v14i2.6

    authors: Oladipo JA

    更新日期:2014-06-01 00:00:00

  • Relationship between plasma homocysteine and blood pressure in hypertensive Northern-Nigerians.

    abstract:Aim:The study sought to determine whether there is any relationship between plasma homocysteine and blood pressure levels in Nigerians with essential hypertension. Method:It was a cross-sectional analytical study done on 120 randomly selected hypertensive patients and 120 normal healthy controls seen at the large Conf...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v20i1.38

    authors: Onyemelukwe OU,Maiha BB

    更新日期:2020-03-01 00:00:00

  • Diagnostic value of glypican-3 in alpha fetoprotein negative hepatocellular carcinoma patients.

    abstract:BACKGROUND:The prognosis of patients with hepatocellular carcinoma(HCC) is generally very poor with a 5-year survival rate of less than 15% since most of them are diagnosed clinically at their late stage. However, the differential diagnosis between alpha fetoprotein(AFP) negative HCC and cirrhotic nodules is still diff...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v13i3.26

    authors: Li B,Liu H,Shang HW,Li P,Li N,Ding HG

    更新日期:2013-09-01 00:00:00

  • Blood loss and contributing factors in femoral fracture surgery.

    abstract:BACKGROUND:Substantial blood losses frequently accompany orthopedic procedures. METHODS:We prospectively noted peri-operative hemoglobin changes in 93 patients undergoing surgery for femoral fracture with an aim of establishing blood loss and related factors. RESULTS:The mean total blood loss assessed 72 hours after ...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Kajja I,Bimenya GS,Eindhoven B,Jan Ten Duis H,Sibinga CT

    更新日期:2010-03-01 00:00:00

  • Fluconazole resistant opportunistic oro-pharyngeal Candida and non-Candida yeast-like isolates from HIV infected patients attending ARV clinics in Lagos, Nigeria.

    abstract:BACKGROUND:Oro-Pharyngeal Candidiasis (OPC) continues to be considered the most common opportunistic fungal disease in HIV/AIDS patients globally. Azole antifungal agent has become important in the treatment of mucosal candidiasis in HIV patients. Presently, antifungal drug resistance is fast becoming a major problem p...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Enwuru CA,Ogunledun A,Idika N,Enwuru NV,Ogbonna F,Aniedobe M,Adeiga A

    更新日期:2008-09-01 00:00:00

  • A case report: the first successful cochlear implant in Uganda.

    abstract::Hearing impairment is a significant disability. According to the World Health Organization (WHO), more than 80% of the world's approximately 120 million people with hearing impairment live in developing countries. Cochlear implant is the only therapeutic intervention for those with severe-profound sensorineural hearin...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v15i4.38

    authors: Byaruhanga R,Roland JT Jr,Buname G,Kakande E,Awubwa M,Ndorelire C,Namwagala J

    更新日期:2015-12-01 00:00:00

  • Parvovirus B19 DNA detection in treatment-naïve HIV anemic patients in Lagos, Nigeria: a case control study.

    abstract:Background:Parvovirus B19 (B19) has tropism for cells of the erythroid lineage, which may lead to transient inhibition of erythropoiesis. Several studies and case reports suggested that B19 infection may contribute significantly to severe chronic anemia in HIV infected persons. Objective:To detect parvovirus B19 DNA i...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v20i1.27

    authors: Ashaka OS,Salu OB,James AB,Oyefolu AOB,Anjorin AA,Oke BO,Orenolu MR,Omilabu SA

    更新日期:2020-03-01 00:00:00

  • Baboons as potential reservoirs of zoonotic gastrointestinal parasite infections at Yankari National Park, Nigeria.

    abstract:BACKGROUND:Zoonoses pose a risk to public health. OBJECTIVE:To carry out the investigation of the prevalence of gastrointestinal parasites of baboons, Papio anubis, frequenting the Wikki base Camp in Yankari National Park, Nigeria. METHOD:Formol-ether concentration technique was used to isolate parasite eggs and cyst...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v13i2.7

    authors: Mafuyai HB,Barshep Y,Audu BS,Kumbak D,Ojobe TO

    更新日期:2013-06-01 00:00:00

  • Is Khat chewing habit a risk factor for occlusal caries progression?

    abstract:Backgrounds:People in Yemen and in East African countries chew khat more than five hours daily. Objectives:The aim of this study was to assess the relationship between khat and occlusal caries progression. Methods:A cohort study was carried out among 98 Yemeni khat chewers and 101 non-chewers aged 18-35 years old wit...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v18i4.25

    authors: Al-Alimi KR,Razak AAA,Saub R

    更新日期:2018-12-01 00:00:00

  • Knowledge, awareness and practice of infection control by health care workers in the intensive care units of a tertiary hospital in Nigeria.

    abstract:Background:Hospital-acquired infections (HAIs), one of the leading causes of, morbidity and mortality, are common in developing countries. Methicillin-resistant staphylococcus aureus (MRSA), commonest cause of HAIs, has been isolated from the hands of more than half of health care workers. Practice of hand hygiene may ...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v18i1.11

    authors: Adegboye MB,Zakari S,Ahmed BA,Olufemi GH

    更新日期:2018-03-01 00:00:00

  • Endoscopic findings in upper gastrointestinal bleeding patients at Lacor hospital, northern Uganda.

    abstract:BACKGROUND:Upper gastrointestinal bleeding (UGIB) is a common emergency medical condition that may require hospitalization and resuscitation, and results in high patient morbidity. Upper gastrointestinal endoscopy is the preferred investigative procedure for UGIB because of its accuracy, low rate of complication, and i...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v12i4.19

    authors: Alema ON,Martin DO,Okello TR

    更新日期:2012-12-01 00:00:00

  • In vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, quinine, mefloquine and halofantrine in Abidjan (Côte d'Ivoire).

    abstract:BACKGROUND:Malaria is the primary cause of hospitalization in Côte d'Ivoire. Early treatment is one of the strategies to control this illness. However, the spread of resistance of Plasmodium falciparum to antimalarial drugs can seriously compromise this strategy. OBJECTIVES:The aim of this study was to assess the in v...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Yavo W,Bla KB,Djaman AJ,Assi SB,Basco LK,Mazabraud A,Koné M

    更新日期:2010-06-01 00:00:00

  • Evaluation of Crimean-Congo hemorrhagic fever suspected cases admitted to a secondary care hospital in Kastamonu, Turkey between 2014-2017.

    abstract:Background:Crimean-Congo hemorrhagic fever (CCHF) is an endemic zoonosis in Kastamonu, Turkey. Clinical and laboratory findings may not be specific in the early phase of the disease, hence bringing a challenge to the clinician. Objective:We aimed to distinguish CCHF cases among all suspected cases by comparing them wi...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v19i1.16

    authors: Gozdas HT

    更新日期:2019-03-01 00:00:00

  • Prevalence and antibiotic susceptibility pattern of bacteriuria among HIV-seropositive patients attending the Bamenda Regional Hospital, Cameroon.

    abstract:Background:HIV causes a decrease in CD4+ lymphocyte cells count, exposing the individual to infections (urinary tract infections). This study was carried out to determine the prevalence of bacteriuria and antimicrobial susceptibility pattern of bacteria isolates among HIV patients. Methods:Clean catch mid-stream urine...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v20i3.7

    authors: Samje M,Yongwa O,Enekegbe AM,Njoya S

    更新日期:2020-09-01 00:00:00

  • Quality of life amongst young adults with stroke living in Kenya.

    abstract:BACKGROUND:The world has been experiencing an increase of stroke among young adults. Occurrence of stroke in young adults dramatically affects the quality of life of the individuals. OBJECTIVES:To investigate the quality of life amongst young adults who experienced a stroke living in Kenya. METHODS:A cross-sectional ...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v13i3.16

    authors: Muli G,Rhoda A

    更新日期:2013-09-01 00:00:00

  • Effect of removal of AuraOnce™ laryngeal mask in awake or deep anaesthesia: a randomized controlled trial.

    abstract:Background:The manufacturer Ambu® recommends that the AuraOnce™ laryngeal mask be removed once the patient is fully awake. Studies have shown benefit in removal of the laryngeal mask airway while a patient is deeply anaesthetized. Current evidence is inconclusive, as to which approach is preferable and safer in adults....

    journal_title:African health sciences

    pub_type: 杂志文章,随机对照试验

    doi:10.4314/ahs.v19i4.16

    authors: Ombaka R,Mung'ayi V,Nekyon D,Mir S

    更新日期:2019-12-01 00:00:00

  • Tuberculosis in children at Mbarara University Teaching Hospital, Uganda: diagnosis and outcome of treatment.

    abstract:BACKGROUND:The diagnosis of tuberculosis in children is difficult particularly in HIV infected children. The poor outcome following antituberculosis treatment usually reported in HIV infected children might be due, in part, to other HIV-related chronic diseases wrongly diagnosed as TB. OBJECTIVE:The study examines the...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Kiwanuka JP

    更新日期:2002-12-01 00:00:00

  • Effects of meteorological factors on the incidence of meningococcal meningitis.

    abstract:BACKGROUND AND OBJECTIVES:Substantial climate changes have led to the emergence and re-emergence of various infectious diseases worldwide, presenting an imperative need to explore the effects of meteorological factors on serious contagious disease incidences such as that of meningococcal meningitis (MCM). METHODS:The ...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v17i3.25

    authors: Bai X,Hu B,Yan Q,Luo T,Qu B,Jiang N,Liu J,Zhu Y

    更新日期:2017-09-01 00:00:00

  • Level of understanding of co-trimoxazole use among HIV infected, recurrent pulmonary tuberculosis suspects at a national referral tuberculosis clinic in Kampala, Uganda: a qualitative analysis.

    abstract:BACKGROUND:Co-trimoxazole use is the standard of care for preventing Pneumocystis jirovecii pneumonia in sub-Saharan Africa but implementation remains slow. Co-trimoxazole is self- administered with uncertain adherence. Knowledge of co-trimoxazole use among HIV infected persons is unknown. OBJECTIVES:To assess knowled...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v15i1.7

    authors: Okwera A,Mafigiri DK,Guwatudde D,Whalen C,Joloba M

    更新日期:2015-03-01 00:00:00

  • Environmental barriers experienced by stroke patients in Musanze district in Rwanda: a descriptive qualitative study.

    abstract:BACKGROUND:Patients with stroke experience a number of environmental barriers, limiting their re-integration. Information regarding the barriers experienced by patients with stroke in a specific setting such as the Musanze district in Rwanda would assist with the development of rehabilitation programmes that would take...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Urimubenshi G,Rhoda A

    更新日期:2011-09-01 00:00:00

  • Rapid screening for co-infection of HIV and HCV in pregnant women in Benin City, Edo State, Nigeria.

    abstract:BACKGROUND:Human Immunodeficiency virus (HIV) and Hepatitis C virus (HCV) are both major global health concerns as they cause high mortality and morbidity in the developing countries. However, while data exists for the co-infection in other countries, little or no information can be found with regard to the sero-preval...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Duru MU,Aluyi HS,Anukam KC

    更新日期:2009-09-01 00:00:00

  • Non-traumatic perforation of the small bowel.

    abstract:BACKGROUND:Non-traumatic perforation of the small bowel is an uncommon serious complication associated with high morbidity and mortality. Diseases that cause small bowel perforation vary in different areas of the world. OBJECTIVE:To highlight difficulties in the diagnosis and management of non-traumatic perforation of...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Eid HO,Hefny AF,Joshi S,Abu-Zidan FM

    更新日期:2008-03-01 00:00:00

  • Intestinal ameliorative effects of traditional Ogi-tutu, Vernonia amygdalina and Psidium guajava in mice infected with Vibrio cholera.

    abstract:BACKGROUND:Cholera, a severe acute watery diarrhea caused by Vibrio cholerae is endemic in Nigeria with most cases occurring in the rural areas. In South West Nigeria, some individuals resort to alternative treatments such as Ogi-tutu, Psidium guajava and Vernonia amygdalina during infections. The effectiveness of thes...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v16i2.33

    authors: Shittu OB,Ajayi OL,Bankole SO,Popoola TO

    更新日期:2016-06-01 00:00:00

  • Exotic and indigenous problem plants species used, by the Bapedi, to treat sexually transmitted infections in Limpopo Province, South Africa.

    abstract:BACKGROUND:The ethnic usage of exotics and indigenous problem plants is a highly debated topic, as legislative requirements over-shadow their potential medicinal value, particularly to treat sexually transmitted infections (STIs). Limited information exists regarding their medicinal value among the Bapedi. OBJECTIVES:...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v13i2.17

    authors: Semenya SS,Potgieter MJ,Erasmus LJ

    更新日期:2013-06-01 00:00:00

  • Trends in rape cases in a Nigerian state.

    abstract:Background:Rape remains a controversial issue with a few victims reporting experience because of the myriad of societal perception, prolonged steps in pursuing a case to logical conclusion of securing conviction, as well as psychological and physical residuals of the experience. Data in Nigeria is therefore hard to com...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v20i2.17

    authors: Idoko CA,Nwobodo E,Idoko CI

    更新日期:2020-06-01 00:00:00