Assessment of drug therapy problem and associated factors among adult hypertensive patients at Ayder comprehensive specialized hospital, Northern Ethiopia.

Abstract:

Background:Drug-therapy problems(DTPs) among hypertensive patients can result in patient's morbidity and mortality. The main aim of this study was to assess drug therapy problem and associated factors among hypertensive patients. Methods:A hospital based cross sectional study was conducted. The data was collected from patients' medical charts and through interview. Drug therapy problem was categorized according to Cipolle methods of DTP classification. Thedata was analyzed using the Statistical Package for the Social Sciences (SPSS), version 21. Results:A total of 241 patients were studied. The mean number of antihypertensive medications prescribed were 1.41±0.53. A total of 357 drug therapy problems(DTPs) were identified. From the patients studied,134(55.6%) had at least one evidence of drug therapy problem. Non adherence was the most commonly identified drug therapy problem occurred in (143(59.3%)) patients. Substance use (AOR=0.445, 95% CI= 0.227-0.870, p=0.018) and comorbidity (AOR= 2.099, 95% CI= 1.192-3.694, p=0.010) werethe predictors of DTP. Conclusion:More than half of the participants had evidence of onset drug therapy problem. Thus efforts that could boost antihypertensive compliance and minimizes substance use should be adopted to reduce patients's drug therapy problems.

journal_name

Afr Health Sci

journal_title

African health sciences

authors

Weldegebreal AS,Tezeta F,Mehari AT,Gashaw W,Dessale KT,Legesse NY

doi

10.4314/ahs.v19i3.33

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

2571-2579

issue

3

eissn

1680-6905

issn

1729-0503

pii

jAFHS.v19.i3.pg2571

journal_volume

19

pub_type

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