Abstract:
Background:Drug-therapy problems(DTPs) among hypertensive patients can result in patient's morbidity and mortality. The main aim of this study was to assess drug therapy problem and associated factors among hypertensive patients. Methods:A hospital based cross sectional study was conducted. The data was collected from patients' medical charts and through interview. Drug therapy problem was categorized according to Cipolle methods of DTP classification. Thedata was analyzed using the Statistical Package for the Social Sciences (SPSS), version 21. Results:A total of 241 patients were studied. The mean number of antihypertensive medications prescribed were 1.41±0.53. A total of 357 drug therapy problems(DTPs) were identified. From the patients studied,134(55.6%) had at least one evidence of drug therapy problem. Non adherence was the most commonly identified drug therapy problem occurred in (143(59.3%)) patients. Substance use (AOR=0.445, 95% CI= 0.227-0.870, p=0.018) and comorbidity (AOR= 2.099, 95% CI= 1.192-3.694, p=0.010) werethe predictors of DTP. Conclusion:More than half of the participants had evidence of onset drug therapy problem. Thus efforts that could boost antihypertensive compliance and minimizes substance use should be adopted to reduce patients's drug therapy problems.
journal_name
Afr Health Scijournal_title
African health sciencesauthors
Weldegebreal AS,Tezeta F,Mehari AT,Gashaw W,Dessale KT,Legesse NYdoi
10.4314/ahs.v19i3.33subject
Has Abstractpub_date
2019-09-01 00:00:00pages
2571-2579issue
3eissn
1680-6905issn
1729-0503pii
jAFHS.v19.i3.pg2571journal_volume
19pub_type
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