Diabetic cardiomyopathy: How can cardiac magnetic resonance help?

abstract：:Overload of reactive oxygen species during diabetes is known to impair cellular homeostasis and to promote deterioration of membrane function in the organism. The aim of the present study was to examine the effect of dietary supplementation with the pyridoindole atioxidant stobadine on functional properties of the ren...

journal_title：Acta diabetologica

authors： Vrbjar N,Strelková S,Stefek M,Kyselová Z,Gajdosíková A

更新日期：2004-12-01 00:00:00

abstract：AIMS:Fat accumulation in the liver and in the muscle results in hepatic and muscle insulin resistance and has been associated with increased cardiovascular risk. It is unclear whether the individual role of hepatic and muscle insulin resistance in the onset of dyslipidaemia is observed in nonalcoholic fatty liver disea...

journal_title：Acta diabetologica

authors： Privitera G,Spadaro L,Alagona C,Calanna S,Piro S,Rabuazzo AM,Purrello F

更新日期：2016-06-01 00:00:00

abstract：:The aim of this research was the evaluation of polymorphonuclear leukocyte (PMN) membrane fluidity in subjects with insulin resistance. Insulin sensitivity, in fact, may be influenced by plasma membrane fluidity. We enrolled 19 subjects with insulin resistance previously demonstrated during an euglycemic hyperinsuline...

journal_title：Acta diabetologica

authors： Caimi G,Sinagra D,Canino B,Scarpitta AM,Montana M,Bonaventura V,Lo Presti R

更新日期：2000-03-01 00:00:00

abstract：:Genetic linkage studies of families with early-onset type 2 diabetes have facilitated the identification of diabetes-susceptibility genes. In order to assess the feasibility of using linkage approaches to identify genes responsible for the development of type 2 diabetes in Japanese subjects, we examined our clinical r...

journal_title：Acta diabetologica

authors： Iwasaki N,Ohgawara H,Nagahara H,Kawamura M,Bell GI,Omori Y

更新日期：1995-03-01 00:00:00

abstract：:The aim of the study was to evaluate the effects of a supervised physical training added to a healthy diet-rich in either carbohydrate and fibre (CHO/fibre) or monounsaturated fatty acids (MUFA)-on postprandial dyslipidaemia, an independent cardiovascular risk factor particularly relevant in type 2 diabetes (T2D). Par...

journal_title：Acta diabetologica

authors： Bozzetto L,Annuzzi G,Costabile G,Costagliola L,Giorgini M,Alderisio A,Strazzullo A,Patti L,Cipriano P,Mangione A,Vitelli A,Vigorito C,Riccardi G,Rivellese AA

更新日期：2014-01-01 00:00:00

abstract：AIMS:Hypoglycaemia represents a critical burden with clinical and social consequences in the management of diabetes. Serum uric acid (SUA) has been associated with cardiovascular diseases (CVD), but no conclusive findings are available nowadays in patients suffering from hypoglycaemia. We investigated whether SUA level...

journal_title：Acta diabetologica

authors： Bonaventura A,Gallo F,Carbone F,Liberale L,Maggi D,Sacchi G,Dallegri F,Montecucco F,Cordera R

更新日期：2018-04-01 00:00:00

abstract：:(31)P-magnetic resonance spectroscopy ((31)P-MRS) is a non-invasive tool to study high-energy phosphate (HEP) metabolism. We evaluate whether 31P-MRS can detect early changes in kidney HEP metabolism during a 6-month trial with Valsartan. Twenty consecutive stable and normotensive kidney-transplanted patients were enr...

journal_title：Acta diabetologica

authors： Fiorina P,Bassi R,Gremizzi C,Vergani A,Caldara R,Mello A,Del Maschio A,De Cobelli F,Perseghin G,Secchi A

更新日期：2012-12-01 00:00:00

abstract：:Most reports of outcome following obesity surgery report weight and co-morbidity changes only. We studied body composition changes in 17 adult patients (15 F, 2 M, age 43+/-2 years, range 28-58 years), with morbid obesity (initial BMI 40.4+/-4.9 kg/m(2), range 34.7-48.8) who were managed surgically by laparoscopically...

journal_title：Acta diabetologica

authors： Strauss BJ,Marks SJ,Growcott JP,Stroud DB,Lo CS,Dixon JB,O'Brien PE

更新日期：2003-10-01 00:00:00

abstract：:The objective of the study was to evaluate the association between infectious diseases and other events pertaining to childhood medical history and type 1 diabetes. A case-control study was carried out, taking as cases 159 type 1 diabetic patients (0-29 years) recorded from 1988 to 2000 within the population registry ...

journal_title：Acta diabetologica

authors： Tenconi MT,Devoti G,Comelli M,Pinon M,Capocchiano A,Calcaterra V,Pretti G,Pavia T1DM Registry Group.

更新日期：2007-03-01 00:00:00

abstract：:Genetic markers may be used to improve the prediction of insulin-dependent diabetes mellitus (type 1) in individuals with islet autoantibodies. In order to develop a risk assessment strategy for the Lombardy region of northern Italy based on genetic and immunological markers, we analyzed HLA DQA1 and DQB1 alleles in 6...

journal_title：Acta diabetologica

authors： Lampasona V,Ferrari M,Bonifacio E,Pastore MR,Carrera P,Sergi A,Genovese S,Trucco M,Dorman J,Bosi E

更新日期：1995-10-01 00:00:00

abstract：:Elevated plasma CT-pro-vasopressin (copeptin) has been described as biomarkers for type 2 diabetes (T2D) and the metabolic syndrome (MetS), which, however, was not confirmed by all studies. Here, we analyzed the association of copeptin with T2D, MetS and MetS components in the population-based KORA F4 study. Plasma co...

journal_title：Acta diabetologica

authors： Then C,Kowall B,Lechner A,Meisinger C,Heier M,Koenig W,Peters A,Rathmann W,Seissler J

更新日期：2015-02-01 00:00:00

abstract：AIMS:Lipohypertrophy (LH) represents the most common skin-related complication associated with insulin therapy. Our aim is to estimate the prevalence of LH among insulin-treated patients, to identify its association with errors in insulin injection technique and storage, and the correlation between LH, risk of hypoglyc...

journal_title：Acta diabetologica

authors： Pozzuoli GM,Laudato M,Barone M,Crisci F,Pozzuoli B

更新日期：2018-01-01 00:00:00

abstract：:The aim of this study is to assess the impact of the internet-based upload blood glucose monitoring and therapy management system (Carelink(®)) in patients with type 1 diabetes. Diabetic patients treated with pump infusion for ≥3 months were prospectively randomized to use the CareLink(®) with (4 months) and without (...

journal_title：Acta diabetologica

authors： Shalitin S,Ben-Ari T,Yackobovitch-Gavan M,Tenenbaum A,Lebenthal Y,de Vries L,Phillip M

更新日期：2014-04-01 00:00:00

abstract：:The aim of this study was to compare the efficacy of treatment with insulin alone, insulin plus acarbose, insulin plus metformin, or insulin plus rosiglitazone in type 2 diabetic subjects who were previously on insulin monotherapy, and to evaluate the effects of these treatments on cardiovascular risk factors includin...

journal_title：Acta diabetologica

authors： Yilmaz H,Gursoy A,Sahin M,Guvener Demirag N

更新日期：2007-12-01 00:00:00

abstract：:Left atrial (LA) structural, functional and mechanical changes have important role in development of diabetic cardiomyopathy and it was discovered that LA remodeling has important prognostic role in the patients with diabetes (DM). Previously the focus of echocardiographic studies in DM population was on the left vent...

journal_title：Acta diabetologica

authors： Tadic M,Cuspidi C

更新日期：2020-06-09 00:00:00

abstract：AIMS:Besides energy supply, β-hydroxybutyrate (BHB) acts as a bioactive molecule to play multiple protective roles, even in diabetes and its complications. The aim of this study was to investigate the antagonizing effects of BHB against diabetic glomerulosclerosis and the underlying mechanism. METHODS:Male Sprague-Daw...

journal_title：Acta diabetologica

authors： Luo W,Yu Y,Wang H,Liu K,Wang Y,Huang M,Xuan C,Li Y,Qi J

更新日期：2020-12-01 00:00:00

abstract：:Anorectic patients who achieve complete recovery from the eating disorder can obtain a favorable psychosocial outcome but the long-term nutritional outcome is ill-defined. We investigated the time course of total and distrectual body composition during and after refeeding in 32 female patients with anorexia nervosa. P...

journal_title：Acta diabetologica

authors： Bertoli S,Corradi E,Vangeli V,Tarlarini P,Salvatori GC,Gentile MG,Testolin G,Battezzati A

更新日期：2004-03-01 00:00:00

abstract：AIMS:To study the incidence of and the factors associated with renal dialysis and transplantation in type 1 (T1DM) and type 2 diabetes (T2DM). METHODS:Data on individuals who had received dialysis treatment or renal transplant between 1 January 2004 and 31 December 2013 were extracted from the regional administrative ...

journal_title：Acta diabetologica

authors： Giorda CB,Carnà P,Salomone M,Picariello R,Costa G,Tartaglino B,Gnavi R

更新日期：2018-07-01 00:00:00

abstract：:We have measured protein phosphatase (PP) activity in crude homogenates as well as in the total 105.000 x g supernatant and precipitate fractions from normal rat pancreatic islets. On the basis of the inhibition produced by either 1 nM or 1 microM okadaic acid, both PP1 and PP2A activity were present in crude islet ho...

journal_title：Acta diabetologica

authors： Gagliardino JJ,Rossi PF,García ME

更新日期：1997-03-01 00:00:00

abstract：AIMS:Diabetic retinopathy (DR) is characterized by early dropout of capillary pericytes, leading to loss of control on endothelial proliferation and, subsequently, angiogenesis. We have demonstrated that extracellular vesicles (EV) derived from mesenchymal stem cells (MSC) maintained in diabetic-like conditions may pla...

journal_title：Acta diabetologica

authors： Mazzeo A,Beltramo E,Iavello A,Carpanetto A,Porta M

更新日期：2015-12-01 00:00:00

abstract：:Despite advances in technology, the frequent self-measurement of blood glucose (SMBG) remains fundamental to the management of 1 diabetes mellitus (T1DM). Once measured, SMBG results are routinely reported back to health professionals and other interested parties, either verbally, via a logbook, or electronically down...

journal_title：Acta diabetologica

authors： Blackwell M,Wheeler BJ

更新日期：2017-01-01 00:00:00

abstract：:The effect of a phenacyl imidazolium compound (LY177507 or Proglycosyn, Eli Lilly) on the direct (glucose-->glucose-6-phosphate-->glycogen) and indirect (three-carbon compounds-->glucose-6-phosphate-->glycogen) pathways of liver glycogen synthesis was studied in conscious rats. [1-13C]Glucose (99% enriched) was infuse...

journal_title：Acta diabetologica

authors： Cline GW,Greenawalt K,Shulman GI

更新日期：1993-01-01 00:00:00

abstract：:Although reactive oxygen species (ROS) contribute to glucose intolerance induced by the renin-angiotensin system (RAS) is well documented, the role of the newly discovered pathway of RAS, angiotensin (Ang)-(1-7)/Mas axis, in this process remains unknown. Here, we examined the effect of Ang-(1-7) on oxidative stress an...

journal_title：Acta diabetologica

authors： Liu C,Lv XH,Li HX,Cao X,Zhang F,Wang L,Yu M,Yang JK

更新日期：2012-08-01 00:00:00

abstract：AIMS:To investigate the possibility of identifying a subtype of latent autoimmune diabetes in adults (LADA), T-LADA (T cell responses-positive and autoantibody-negative) from patients with phenotypic type 2 diabetes (T2D) by enzyme-linked immunospot (ELISPOT). METHODS:Eighty-two patients with phenotypic T2D were studi...

journal_title：Acta diabetologica

authors： Liang H,Cheng Y,Tang W,Cui Q,Yuan J,Huang G,Yang L,Zhou Z

更新日期：2019-11-01 00:00:00

abstract：AIM:Infection of a diabetic foot ulcer (DFU) is common. More than the half of DFUs become infected and 15-20% of them necessitate amputation in course of treatment. Diabetic foot infection (DFI) is therefore the major cause for non-traumatic lower limb amputation in Germany. Prompt and effective treatment of DFI is man...

journal_title：Acta diabetologica

authors： Dörr S,Freier F,Schlecht M,Lobmann R

更新日期：2020-09-17 00:00:00

abstract：:In the perfused pancreas of adult rats that were injected with streptozotocin (STZ) during the neonatal period, the release of insulin caused by glucose is more severely affected than that evoked by other secretagogues. We have now examined whether a comparable situation prevails in vivo. In anesthetised rats, the 0-1...

journal_title：Acta diabetologica

authors： Vicent D,Villanueva-Peñacarrillo ML,Valverde I,Malaisse WJ

更新日期：1994-09-01 00:00:00

abstract：:It usually takes several years (in some cases, decades) for predisposed individuals to move from the onset of type 1 or type 2 diabetes to the development of microalbuminuria, the first sign of diabetic nephropathy. This long, complication-free, period represents the best possible moment to start a successful preventi...

journal_title：Acta diabetologica

authors： Maestroni S,Zerbini G

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Despite advances in the medical management of type 1 diabetes mellitus (T1DM), for many, glycaemic control remains substandard. Other factors are clearly important in determining success, or lack thereof, with diabetes management. With this in mind, we have investigated whether family CHAOS may provide a nov...

journal_title：Acta diabetologica

authors： Chae M,Taylor BJ,Lawrence J,Healey D,Reith DM,Gray A,Wheeler BJ

更新日期：2016-02-01 00:00:00

abstract：:The renin-angiotensin system (RAS) has an important role in the endocrine pancreas. Multiple researches have shown that even in the insulin resistance phase, there are many abnormalities in islets morphology and function. This study aimed at investigating the effects of RAS blockade on the islets function in rats with...

journal_title：Acta diabetologica

authors： Yuan L,Li X,Li J,Li HL,Cheng SS

更新日期：2013-08-01 00:00:00

abstract：:Sourdough bread has been reported to improve glucose metabolism in healthy subjects. In this study postprandial glycaemic and insulinaemic responses were evaluated in subjects with impaired glucose tolerance (IGT) who had a meal containing sourdough bread leavened with lactobacilli, in comparison to a reference meal c...

journal_title：Acta diabetologica

authors： Maioli M,Pes GM,Sanna M,Cherchi S,Dettori M,Manca E,Farris GA

更新日期：2008-06-01 00:00:00