Abstract：
BACKGROUND:Despite advances in the medical management of type 1 diabetes mellitus (T1DM), for many, glycaemic control remains substandard. Other factors are clearly important in determining success, or lack thereof, with diabetes management. With this in mind, we have investigated whether family CHAOS may provide a novel tool to identify when environmental confusion could impact on diabetes management and subsequent glycaemic control. METHODS:A case-control study of children and adolescents with established T1DM and age-/sex-matched controls was conducted. Demographic information, both maternal and paternal CHAOS scores, and HbA1c were collected. Statistical analysis was undertaken to explore associations between T1DM and CHAOS and between CHAOS and HbA1c. RESULTS:Data on 65 children with T1DM and 60 age-/sex-matched controls were obtained. There was no evidence of group differences for maternal CHAOS (p = 0.227), but paternal CHAOS scores were higher for the T1DM group (p = 0.041). Greater maternal and paternal CHAOS scores were both associated with higher HbA1c (p ≤ 0.027). The maternal association remained after controlling for diabetes duration, SMBG frequency, and insulin therapy. CONCLUSION:In children with T1DM, there appears to be a negative association between increased environmental confusion, as rated by CHAOS, and glycaemic control. In addition, when compared to controls, fathers of children and adolescents with T1DM appear to experience CHAOS differently to mothers. These findings contribute to the growing body of literature exploring psychosocial factors in T1DM. Continuing efforts are required to fully understand how the family and psychosocial environment interact with diabetes to impact on long-term health outcomes.
journal_name
Acta Diabetoljournal_title
Acta diabetologicaauthors
Chae M,Taylor BJ,Lawrence J,Healey D,Reith DM,Gray A,Wheeler BJdoi
10.1007/s00592-015-0736-xsubject
Has Abstractpub_date
2016-02-01 00:00:00pages
49-55issue
1eissn
0940-5429issn
1432-5233pii
10.1007/s00592-015-0736-xjournal_volume
53pub_type
杂志文章abstract：:Aim To summarize, critically review, and interpret the evidence related to the systematic reviews on health literacy (HL) amongst type 2 diabetes mellitus (T2DM). Methods The methodology for this study consisted of a systematic review of systematic reviews, using the PRISMA statement and flowchart to select studies, a...
journal_title：Acta diabetologica
pub_type： 杂志文章,评审
doi：10.1007/s00592-017-1071-1
更新日期：2018-01-01 00:00:00
abstract：AIMS:Our aims were to investigate in several large samples, with a wide range of adiposity, whether: (1) the effect of BMI on insulin sensitivity is different between sexes; (2) also waist circumference plays a sex-specific role on insulin sensitivity; and (3) serum adiponectin and resistin are mediators of such sex-di...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/s00592-015-0804-2
更新日期：2015-10-01 00:00:00
abstract：:This 64-week prospective cohort trial evaluated the effects of 20-mg oestradiol implants, replaced every 4 months, in healthy postmenopausal women aged 45-65 years. Of 20 implant and 14 control subjects who remained in the trial at 32 weeks, 13 implant and seven controls continued to 64 weeks, with no baseline differe...
journal_title：Acta diabetologica
pub_type： 临床试验,杂志文章
doi：10.1007/s00592-003-0063-5
更新日期：2003-10-01 00:00:00
abstract：:The objective of the study was to evaluate the association between infectious diseases and other events pertaining to childhood medical history and type 1 diabetes. A case-control study was carried out, taking as cases 159 type 1 diabetic patients (0-29 years) recorded from 1988 to 2000 within the population registry ...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/s00592-007-0235-9
更新日期：2007-03-01 00:00:00
abstract：AIMS:Familial partial lipodystrophy (FPLD) is a rare autosomal dominant disorder, mostly due to mutations in lamin A (LMNA) or in peroxisome proliferator-activated receptor gamma (PPARG) genes. In the present study, we aimed to identify and functionally characterize the genetic defect underlying FPLD in an Italian fami...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/s00592-019-01462-y
更新日期：2020-05-01 00:00:00
abstract：:A meta-analysis was performed in order to test the hypothesis that Japanese have a greater amount of abdominal visceral fat (AVF) relative to abdominal subcutaneous fat (ASF) than Caucasians. Data were derived from published studies that included mean values for AVF and ASF areas, measured using computed tomography, a...
journal_title：Acta diabetologica
pub_type： 杂志文章,meta分析
doi：10.1007/s00592-003-0093-z
更新日期：2003-10-01 00:00:00
abstract：AIMS:High glycemic variability (GV) is the major indication for islet transplantation (IT) in patients with type 1 diabetes (T1D). The actual criteria used to assess graft function do not consider GV improvement. Our study aimed to describe GV indices' evolution in T1D patients who benefited from IT during the TRIMECO ...
journal_title：Acta diabetologica
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00592-019-01425-3
更新日期：2020-03-01 00:00:00
abstract：:The effect of a phenacyl imidazolium compound (LY177507 or Proglycosyn, Eli Lilly) on the direct (glucose-->glucose-6-phosphate-->glycogen) and indirect (three-carbon compounds-->glucose-6-phosphate-->glycogen) pathways of liver glycogen synthesis was studied in conscious rats. [1-13C]Glucose (99% enriched) was infuse...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/BF00578216
更新日期：1993-01-01 00:00:00
abstract：:Rosiglitazone often results in weight gain. We hypothesized that rosiglitazone may modulate circulating levels of ghrelin and peptide YY(3-36) and this modulation may be related to weight-gaining effect of this agent. This study was designed as an open-label, randomized, controlled trial of 3-month duration. Women wit...
journal_title：Acta diabetologica
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00592-011-0352-3
更新日期：2012-12-01 00:00:00
abstract：:Insulin secretion is stimulated better by oral than by intravenous glucose (incretin effect). The contribution of the autonomic nervous system to the incretin effect after oral glucose in humans is unclear. We therefore examined nine type 1 diabetic (insulin-dependent) patients with end-stage nephropathy, studied afte...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/BF00572873
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:Psychosocial factors like diabetes distress and social support, as well as the presence of complications, affect an individual's self-management ability; however, their role in adherence behaviours is not yet clear. We examined the role of psychosocial factors and complications in non-adherence behaviours in...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/s00592-020-01609-2
更新日期：2020-11-19 00:00:00
abstract：BACKGROUND:Circulating levels of TNF alpha receptor 1 (TNFR1) and 2 (TNFR2) are associated with increased long-term mortality and impaired kidney function. AIM:To study association between circulating levels of TNFR1 and TNFR2 and short-term mortality in patients with diabetes and dyspnea. POPULATION AND METHODS:Pati...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/s00592-020-01527-3
更新日期：2020-10-01 00:00:00
abstract：:Concentrations of soluble receptors for tumor necrosis factor (p55 and p75) strongly correlate with clinical stage and progression of infectious diseases, and may be useful in monitoring autoimmune diseases. However, the role of soluble TNF receptors in insulin-dependent diabetes mellitus (type 1 DM) is not clear. We ...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/s005920050152
更新日期：1999-06-01 00:00:00
abstract：:Positron emission tomography/computed tomography (PET/CT) is a standard procedure for imaging cancer commonly used in the clinical practice for several diseases, in particular for cancer staging, restaging, treatment monitoring and radiation therapy planning. Despite the availability of many radiotracers, 18F-fluoro-2...
journal_title：Acta diabetologica
pub_type： 杂志文章,评审
doi：10.1007/s00592-019-01385-8
更新日期：2020-03-01 00:00:00
abstract：AIMS:Hyperreflective foci (HF), detected in the retina of diabetic patients, suggest the presence of microglial activation and migration, while controversies still remain for the origin of HF to be precursors of hard exudates. We investigated the presence of HF and their association with dyslipidemia in serous retinal ...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/s00592-020-01495-8
更新日期：2020-07-01 00:00:00
abstract：:The objective is to assess the effect of TNF-alpha inhibition on urinary albumin excretion in experimental diabetic rats. Male Wistar rats, 8-week-old, were categorized into four groups, which were the control (n = 9), diabetes (n = 9), infliximab-treated diabetes (n = 10), and FR167653-treated diabetes (n = 9) groups...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/s00592-007-0007-6
更新日期：2007-12-01 00:00:00
abstract：:The purpose of this study is to identify the recent characteristics and the developments of therapeutic education in diabetes through an analysis of the international articles published from 2004 to 2007. Studies were selected from several databases: Medline, Embase, Eric, Cochrane central database, using the followin...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/s00592-008-0044-9
更新日期：2008-12-01 00:00:00
abstract：:Cardiovascular diseases represent, today, the principal cause of mortality in the general population, especially in subjects with type 2 diabetes mellitus. In these patients the risk of death from cardiovascular diseases is equal to that of non-diabetic subjects with a previous episode of myocardial infarction. Many f...
journal_title：Acta diabetologica
pub_type： 杂志文章,评审
doi：10.1007/s00592-003-0121-z
更新日期：2003-12-01 00:00:00
abstract：:Although reactive oxygen species (ROS) contribute to glucose intolerance induced by the renin-angiotensin system (RAS) is well documented, the role of the newly discovered pathway of RAS, angiotensin (Ang)-(1-7)/Mas axis, in this process remains unknown. Here, we examined the effect of Ang-(1-7) on oxidative stress an...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/s00592-011-0348-z
更新日期：2012-08-01 00:00:00
abstract：:Islet autotransplantation (IAT) is performed at the time of total pancreatectomy (TP) to prevent or minimize post-surgical diabetes. Corticosteroids induce insulin resistance and present a risk to islet autografts, through glucotoxicity and increased metabolic demand on a marginal islet mass. We present four IAT recip...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/s00592-011-0315-8
更新日期：2014-02-01 00:00:00
abstract：AIMS:The anti-inflammatory effects of the polyphenol resveratrol in patients with type 2 diabetes mellitus (T2DM) are controversial. Its role on pentraxin 3 (PTX3) concentrations, a human acute phase protein, has never been evaluated. Our aim was to determine whether a two-dosage resveratrol supplementation (500 and 40...
journal_title：Acta diabetologica
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00592-017-0977-y
更新日期：2017-05-01 00:00:00
abstract：AIMS:Lipohypertrophy (LH) represents the most common skin-related complication associated with insulin therapy. Our aim is to estimate the prevalence of LH among insulin-treated patients, to identify its association with errors in insulin injection technique and storage, and the correlation between LH, risk of hypoglyc...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/s00592-017-1066-y
更新日期：2018-01-01 00:00:00
abstract：AIMS:Diabetic retinopathy (DR) is characterized by early dropout of capillary pericytes, leading to loss of control on endothelial proliferation and, subsequently, angiogenesis. We have demonstrated that extracellular vesicles (EV) derived from mesenchymal stem cells (MSC) maintained in diabetic-like conditions may pla...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/s00592-015-0798-9
更新日期：2015-12-01 00:00:00
abstract：:In late twentieth century, Ruderman and Reaven showed that insulin resistance might be fundamental to metabolic syndrome (MetS) which means a constellation of obesity-related metabolic derangements predisposing to type 2 diabetes and cardiovascular disease. In 2001, user-friendly National Cholesterol Education Program...
journal_title：Acta diabetologica
pub_type： 历史文章,杂志文章,评审
doi：10.1007/s00592-011-0309-6
更新日期：2012-04-01 00:00:00
abstract：AIMS:Besides energy supply, β-hydroxybutyrate (BHB) acts as a bioactive molecule to play multiple protective roles, even in diabetes and its complications. The aim of this study was to investigate the antagonizing effects of BHB against diabetic glomerulosclerosis and the underlying mechanism. METHODS:Male Sprague-Daw...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/s00592-020-01552-2
更新日期：2020-12-01 00:00:00
abstract：:Bacterial endotoxins have been associated with chronic inflammation and the development and progression of diabetic nephropathy. We hypothesized that subjects with high serum lipopolysaccharide activity also carry remains of bacterial DNA in their system. Serum-derived bacterial DNA clones were isolated and identified...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/s00592-012-0421-2
更新日期：2013-06-01 00:00:00
abstract：:Left atrial (LA) structural, functional and mechanical changes have important role in development of diabetic cardiomyopathy and it was discovered that LA remodeling has important prognostic role in the patients with diabetes (DM). Previously the focus of echocardiographic studies in DM population was on the left vent...
journal_title：Acta diabetologica
pub_type： 杂志文章,评审
doi：10.1007/s00592-020-01557-x
更新日期：2020-06-09 00:00:00
abstract：AIM:To identify the potential metabolite markers in diabetic retinopathy (DR) by using gas chromatography coupled with time-of-flight mass spectrometry (GC-TOFMS). METHODS:GC-TOFMS spectra were acquired from vitreous and aqueous humor (AH) samples of patients with DR and non-diabetic participants. Comparative analysis...
journal_title：Acta diabetologica
pub_type： 杂志文章
doi：10.1007/s00592-019-01363-0
更新日期：2020-01-01 00:00:00
abstract：AIMS:To assess the risk of adverse neonatal outcomes in women with gestational diabetes (GDM) by identifying subgroups of women at higher risk to recognize the characteristics most associated with an excess of risk. METHODS:Observational, retrospective, multicenter study involving consecutive women with GDM. To identi...
journal_title：Acta diabetologica
pub_type： 杂志文章,多中心研究
doi：10.1007/s00592-018-1208-x
更新日期：2018-12-01 00:00:00
abstract：:The aim of this study is to assess the impact of the internet-based upload blood glucose monitoring and therapy management system (Carelink(®)) in patients with type 1 diabetes. Diabetic patients treated with pump infusion for ≥3 months were prospectively randomized to use the CareLink(®) with (4 months) and without (...
journal_title：Acta diabetologica
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00592-013-0510-x
更新日期：2014-04-01 00:00:00
