Abstract:
:In this study, we performed the first high-throughput and comprehensive proteomic profiling of the rat hippocampal proteome. Using a combination of 2-D LC-MS and data analysis with the Rosetta Elucidator(®) system, we identified 1340 unique proteins. Functional classification showed that most of these were associated with synaptic function and comprised a high proportion of phosphorylated proteins and analytically challenging classes of membrane proteins such as ion channel receptor subunits.
journal_name
Proteomicsjournal_title
Proteomicsauthors
Yang X,Levin Y,Rahmoune H,Ma D,Schöffmann S,Umrania Y,Guest PC,Bahn Sdoi
10.1002/pmic.201000525subject
Has Abstractpub_date
2011-02-01 00:00:00pages
501-5issue
3eissn
1615-9853issn
1615-9861journal_volume
11pub_type
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