Abstract:
OBJECTIVES:Outcomes of childhood obesity interventions are rarely reported beyond 1 year. We hypothesized that the impact on the BMI z score from a child-centered physical-activity program in combination with a parent-centered dietary-modification program would be greater than either program conducted alone at 24 months' after baseline. PARTICIPANTS AND METHODS:A total of 165 overweight prepubertal children (68 boys, aged 5.5-9.9 years, mean BMI z score: 2.8) were randomly assigned to either a child-centered physical-activity program, a parent-centered dietary-modification program, or both conducted together in an assessor-blinded 6-month intervention. RESULTS:Using linear mixed models, all groups reduced their mean (95% confidence interval) BMI z score at 24 months from baseline (P < .001) (the activity and diet group: -0.24 [-0.35 to -0.13]; the diet-only group: -0.35 [-0.48 to -0.22]; activity-only group -0.19 [-0.30 to -0.07]). There was a significant group-by-time interaction (P = .04) with the activity + diet and the diet-only groups showing a greater reduction than the activity-only group. For waist z score and waist-to-height ratio, there was a significant time effect (P < .0001) at 24 months but no between-group differences (P > .05). Some metabolic outcomes improved at 24 months, although there were no between-group differences (P > .05). CONCLUSIONS:A reduction in BMI z score was sustained at 24 months by treatment with either program combination. The greatest effects were achieved through inclusion of a parent-centered diet program, indicating the importance of targeting parents within treatment and the possibility of targeting them exclusively in treating obese prepubertal children.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Collins CE,Okely AD,Morgan PJ,Jones RA,Burrows TL,Cliff DP,Colyvas K,Warren JM,Steele JR,Baur LAdoi
10.1542/peds.2010-1518subject
Has Abstractpub_date
2011-04-01 00:00:00pages
619-27issue
4eissn
0031-4005issn
1098-4275pii
peds.2010-1518journal_volume
127pub_type
杂志文章,多中心研究,随机对照试验相关文献
PEDIATRICS文献大全abstract:OBJECTIVE:This study examines the relationship of intrauterine growth, measured by size and maturity at birth, to age at menarche, while also considering a wide range of other factors that may affect maturation. The research is motivated by the current debate about the importance of the prenatal environment as a determ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.107.4.e59
更新日期:2001-04-01 00:00:00
abstract::The b-CAPSA I capsular polysaccharide vaccine for Haemophilus influenzae type b was given to 87,541 children 2 through 5 years of age in the Kaiser Permanente Medical Care Program, and the children were then followed using a multiple modality surveillance. Phase 1 consisted of 24-hour recall of immediate side effects ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1987-03-01 00:00:00
abstract::Cat scratch disease is a benign, self-limited illness characterized by regional lymphadenopathy that usually occurs in association with a history of contact with a cat. Cases of cat scratch disease with skin manifestations that included erythema nodosum; erythema multiforme; erythema marginatum; and non-specific macul...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1988-04-01 00:00:00
abstract::Delayed initiation of proper therapy for infants with primary infantile glaucoma results in an unnecessarily poor outcome. In an effort to understand why some infants and children had more advanced disease than others, researchers reviewed the records of 24 consecutive infants and children with this problem. The prese...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1986-03-01 00:00:00
abstract::Infants born to women who are asymptomatic hepatitis B surface antigen (HBsAg) carriers frequently acquire hepatitis B virus infection in infancy. The spectrum of disease in such affected infants includes mild transient acute hepatitis B, chronic active hepatitis with or without cirrhosis, chronic persistent hepatitis...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1983-08-01 00:00:00
abstract::Thirty-eight consecutive children with recurrent abdominal pain underwent lactose tolerance tests; 28 of these were also given sucrose tolerance tests. Abdominal pain and abnormal lactose tolerance tests were noted in 11 of 38, while none of the 28 had an abnormal sucrose tolerance test; however, 1 had abdominal pain....
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1979-07-01 00:00:00
abstract:OBJECTIVE:Residential exposures are recognized risk factors for childhood asthma, but the relative contribution of specific risk factors and the overall contribution of housing to asthma in US children is unknown. The objective of this study was to identify risk factors and estimate the population attributable risk of ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.107.3.505
更新日期:2001-03-01 00:00:00
abstract::This article, written by a group of experienced parents of children with medical complexity (CMC), provides an overview of the demands of managing care from their unique perspective. The article articulates why attention to understanding the challenges that families of CMC face with a fragmented health care system, in...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2017-1284D
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:In past decades, numerous population- and hospital-based studies have revealed a relationship between migraine or headache and psychopathology in children. OBJECTIVE:To describe and assess all clinical studies on the prevalence and manifestations of psychological functioning and psychiatric comorbidity in c...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2009-3293
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:Although it is well documented that breastfeeding promotes health and development of very low birth weight (VLBW) infants, lactation initiation among mothers of VLBW infants is low. Mothers are anxious about the health of their children, and medical staff may be reluctant to promote breastfeeding out of conce...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-0267
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Lithium is a benchmark treatment for bipolar disorder in adults. Definitive studies of lithium in pediatric bipolar I disorder (BP-I) are lacking. METHODS:This multicenter, randomized, double-blind, placebo-controlled study of pediatric participants (ages 7-17 years) with BP-I/manic or mixed episodes compar...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2015-0743
更新日期:2015-11-01 00:00:00
abstract::Agriculture is the second most dangerous occupation in the United States, and unlike other occupations, children make up a significant portion of the work force. This study presents national data on the morbidity and mortality due to farm injuries to children and adolescents less than or equal to 19 years of age. Data...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1985-10-01 00:00:00
abstract:OBJECTIVE:To determine appropriate upper limits for gestational age and birth weight when screening infants for retinopathy of prematurity (ROP). DESIGN:Retrospective survey. SETTING:Tertiary neonatal intensive care nursery. PATIENTS:Seven hundred seven infants born July 1, 1990 to June 30, 1996 and screened for ROP...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.102.1.31
更新日期:1998-07-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to use nationwide registries to examine the health of children up to 4 years of age who were born as a result of in vitro fertilization. METHODS:Children born after in vitro fertilization (N = 4559) from 1996 to 1999 were monitored until 2003. Two control groups were selected fr...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-0735
更新日期:2006-11-01 00:00:00
abstract::Children's hospitals play a central role in our child health care system. These hospitals face unique challenges under health care reform. They care for children with the most complex medical problems but often are not reimbursed for good preventive care, care coordination, or quality. We discuss a proposal by childre...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2013-0252g
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVE:The prevalence of autism spectrum disorder is steadily increasing and placing more demands on already overburdened diagnostic and treatment systems. A thoughtful, systematic reorganization of autism service delivery may reduce delays and better meet the growing need. METHODS:Two clinical centers in the Autis...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-2851M
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:The association of dietary fat distribution with markers of subclinical atherosclerosis during early life is unknown. We examined whether success in achieving the main target of an infancy-onset dietary intervention based on the distribution of dietary fat was associated with aortic and carotid intima-media ...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2019-2786
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Adults born at a very low birth weight (VLBW) (< 1500 g), compared with those born at term, bear risk factors for cardiovascular disease, including higher blood pressure and insulin resistance. OBJECTIVE:We studied, in young adults born at a VLBW, early signs of an accelerated atherosclerotic process and th...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2010-2199
更新日期:2011-02-01 00:00:00
abstract::Resistance to thyroid hormone is an uncommon problem, which has rarely been associated with thyroid dysgenesis. We report a case with both thyroid gland ectopy and resistance to thyroid hormone and, thus, a reduced capacity to produce and respond to thyroid hormone. The patient presented at 2 years of age with develop...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-0634
更新日期:2012-03-01 00:00:00
abstract::After a brief explanation of the immunization policy in the Netherlands, the national immunization program is described, with special attention given to coupling of the municipal population records with a computerized database of individual immunization records at the provincial level. The Dutch program achieves cover...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-12-01 00:00:00
abstract:OBJECTIVES:With this study we aimed to compare survival rates for children with Down syndrome in 2 time periods, 1 before prenatal screening (1988-1990) and 1 contemporaneous with screening (1998-2000), and to examine the frequency of comorbidities and their influence on survival rates. METHODS:Record-linkage was perf...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2007-2840
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:E-cigarette use is rapidly increasing among adolescents in the United States, with some suggesting that e-cigarettes are the cause of declining youth cigarette smoking. We hypothesized that the decline in youth smoking changed after e-cigarettes arrived on the US market in 2007. METHODS:Data were collected ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2016-2450
更新日期:2017-02-01 00:00:00
abstract:CONTEXT AND OBJECTIVE:Primary generalized tonic-clonic seizures are relatively more common among children than among adults. Primary generalized tonic-clonic seizures are associated with increased risk of injury and death. Therefore, effective control of primary generalized tonic-clonic seizures is necessary to reduce ...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2006-0148
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVES:The objectives of this study were to characterize noise and light levels for extremely low birth weight newborns throughout their stay in the NICU, evaluate factors influencing noise and light levels, and determine whether exposures meet recommendations from the American Academy of Pediatrics. METHODS:Sound...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2007-3418
更新日期:2009-02-01 00:00:00
abstract::The confusing area of cow's milk intolerance is explored in an attempt to define the various mechanisms whereby milk affects gastrointestinal function, resulting in clinical symptoms (diarrhea, vomiting, gastrointestinal bleeding, etc.). The adverse reaction of infants to cow's milk ingestion may relate to lactose int...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1977-10-01 00:00:00
abstract::Varicella is a nearly ubiquitous acquired childhood disease. Infectious complications of varicella can be life- or limb-threatening. These complications appear 3 to 4 days after the appearance of varicella exanthem and are heralded by fever, pain, and erythema of the overlying skin. Airway complications of varicella a...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.105.1.e13
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Studies suggest that giving newly born preterm infants sustained lung inflation (SLI) may decrease their need for mechanical ventilation (MV) and improve their respiratory outcomes. METHODS:We randomly assigned infants born at 25 weeks 0 days to 28 weeks 6 days of gestation to receive SLI (25 cm H2O for 15 ...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2014-1692
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to determine the prevalence of severe fatigue in adolescent boys and girls, to explore the role of lifestyle factors in fatigue, and to investigate whether severe fatigue in a healthy population is associated with depression, anxiety, and comorbid factors also observed in chronic...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-2575
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVE:The goal of this study was to evaluate the impact of the Active Teen Leaders Avoiding Screen-time (ATLAS) intervention for adolescent boys, an obesity prevention intervention using smartphone technology. METHODS:ATLAS was a cluster randomized controlled trial conducted in 14 secondary schools in low-income c...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2014-1012
更新日期:2014-09-01 00:00:00
abstract::Immigrant children seeking safe haven in the United States, whether arriving unaccompanied or in family units, face a complicated evaluation and legal process from the point of arrival through permanent resettlement in communities. The conditions in which children are detained and the support services that are availab...
journal_title:Pediatrics
pub_type: 历史文章,杂志文章
doi:10.1542/peds.2017-0483
更新日期:2017-05-01 00:00:00