Abstract:
:The confusing area of cow's milk intolerance is explored in an attempt to define the various mechanisms whereby milk affects gastrointestinal function, resulting in clinical symptoms (diarrhea, vomiting, gastrointestinal bleeding, etc.). The adverse reaction of infants to cow's milk ingestion may relate to lactose intolerance (enzymatic), a direct toxic reaction to the mucosal surface resulting in epithelial damage, or it may be immunologically mediated. Factors such as increased intestinal permeability to milk proteins during the newborn period may also contribute to susceptibility of young infants to milk sensitivity. The relative roles of systemic (milk agglutinins) and local immunity (SIgA antibodies) in milk intolerance are discussed and differential immunologic responses (IgE versus IgA/IgM) considered in the pathogenesis. It was concluded that new techniques such as organ culture of intestinal biopsy specimens are needed to establish the diagnosis of hypersensitivity and to begin to provide ways of adequately treating the condition.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Eastham EJ,Walker WAsubject
Has Abstractpub_date
1977-10-01 00:00:00pages
477-81issue
4eissn
0031-4005issn
1098-4275journal_volume
60pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract::Children's hospitals play a central role in our child health care system. These hospitals face unique challenges under health care reform. They care for children with the most complex medical problems but often are not reimbursed for good preventive care, care coordination, or quality. We discuss a proposal by childre...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2013-0252g
更新日期:2013-04-01 00:00:00
abstract::In a previously described population of 314 autistic and 237 dysphasic nonautistic children, after exclusion of 12 autistic girls with Rett syndrome, 14% (42 of 302) of autistic children and 8% (19 of 237) of dysphasic children had epilepsy (P = .03). The major risk factors for epilepsy were severe mental deficiency a...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-12-01 00:00:00
abstract::Vocal cord paralysis associated with goiter usually indicates the presence of a malignancy. Pediatric patients retain significant thymic tissue that regresses only later in life. This thymic tissue can develop significant hyperplasia during an acute autoimmune process. We describe a case of a 17-year-old girl who pres...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2013-0437
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:Although caffeine use for apnea of prematurity is well studied, the long-term safety and benefit of routine early caffeine administration has not been explored. Our objective was to determine the association between early (within 2 days of birth) versus late caffeine exposure and neurodevelopmental outcomes ...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.2018-1348
更新日期:2019-01-01 00:00:00
abstract:CONTEXT:Research reveals racial, ethnic, and socioeconomic disparities in autism diagnosis; there is limited information on potential disparities related to other dimensions of services. OBJECTIVE:We reviewed evidence related to disparities in service use, intervention effectiveness, and quality of care provided to ch...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-1895G
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Not enough is known about the national prevalence of racial/ethnic disparities in children's medical and dental care. OBJECTIVE:The purpose of this work was to examine racial/ethnic disparities in medical and oral health, access to care, and use of services in a national sample. METHODS:The National Survey...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2007-1243
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVE:Our goal was to test the hypothesis that increased fruit juice intake and parental restriction of children's eating are associated with increased adiposity gain and whether exposure to nutritional counseling predicted reduced adiposity gain among children. PATIENTS AND METHODS:A sample of parents or guardian...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-1117
更新日期:2006-11-01 00:00:00
abstract::The head circumference (HC) curves were plotted for a group of 415 healthy full-term babies over the first 2 years of life. Two hundred ten (51%) of the cohort demonstrated HC variability, defined as an HC acceleration or deceleration of at least 1 centile curve for at least 2 months. Of these, the deceleration patter...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-08-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to determine the risk for separation (ending cohabitation) of the parents of a child with a diagnosis of cancer. METHODS:In a nationwide cohort, we compared the risk for ending cohabitation of the parents of 2450 children (aged 0-20 years) given a diagnosis of cancer with the ri...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-2657
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:To determine whether children with unilateral hearing loss (UHL) demonstrate worse language skills than their siblings with normal hearing, and whether children with UHL are more likely to receive extra assistance at school. PATIENTS AND METHODS:We conducted a case-control study of 6- to 12-year-old children...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2009-2448
更新日期:2010-06-01 00:00:00
abstract::Localized abscess formation is a rare but previously described manifestation of Haemophilus influenzae infection. A majority of the reported cases were caused by nontypeable strains of H influenzae. We report a case of an extensive subscapular abscess due to beta-lactamase-negative H influenzae type B. This, to our kn...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1980-02-01 00:00:00
abstract:OBJECTIVES:To study the outcome at 2-year corrected age of infants who participated in a double-blind controlled trial of early (<12 hours) dexamethasone therapy for the prevention of chronic lung disease (CLD). METHODS AND MATERIALS:A total of 133 children (70 in the control group, 63 in the dexamethasone-treated gro...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.101.5.e7
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVE:To determine whether state booster seat laws were associated with decreased fatality rates in children 4 to 7 years of age in the United States. METHODS:Retrospective, longitudinal analysis of all motor vehicle occupant crashes involving children 4 to 7 years of age identified in the Fatality Analysis Report...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2012-1058
更新日期:2012-12-01 00:00:00
abstract::Chronic intestinal pseudo-obstruction is a rare disorder that affects the motility of the gastrointestinal tract. It results in acute or subacute intestinal obstruction symptoms in the absence of mechanical lesion. It can lead to intestinal failure in children with significant strain on nutrition, growth, and developm...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2017-0007
更新日期:2018-04-01 00:00:00
abstract::The infant rumination syndrome has not been previously reported in a neonatal intensive care setting. We recently managed three infants in our newborn intensive care unit who developed rumination following chronic courses in the unit. The events leading to this condition in each infant are described, as well as the su...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1980-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Recent years have witnessed substantial gains in health insurance coverage for children, but few studies have examined trends across a diverse set of access indicators. We examine US children's access to health services and whether trends vary by race/ethnicity and income. METHODS:Analysis of ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2016-2176
更新日期:2016-12-01 00:00:00
abstract::The purpose of this statement is to update recommendations for the routine use of seasonal influenza vaccine and antiviral medications for the prevention and treatment of influenza in children. The AAP recommends annual seasonal influenza immunization for everyone 6 months and older, including children and adolescents...
journal_title:Pediatrics
pub_type: 杂志文章,实务指引
doi:10.1542/peds.2016-2527
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Maternal smoking increases the risk for preterm birth, low birth weight, and sudden infant death syndrome, which are all causes of infant mortality. Our objective was to evaluate if changes in cigarette taxes and prices over time in the United States were associated with a decrease in infant mo...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-2901
更新日期:2016-01-01 00:00:00
abstract::In a quality and cost-conscious health care environment, the pediatrician and emergency physician must work as a team. This statement clarifies important issues of this relationship, including coordination of patient care, communication between clinicians, provision of continuity care, and responsibility for quality e...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.101.5.936
更新日期:1998-05-01 00:00:00
abstract::The presentation of parental anxiety that appears excessive in view of the nature of the child's "chief complaint" is a frequent occurrence in pediatric practice. This study reviews 370 sick-patient visits in one pediatric office during a three-month period. Additional questioning in the area of parental anxieties con...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1982-12-01 00:00:00
abstract::This is a joint policy statement from the American Academy of Pediatrics, American College of Emergency Physicians, Emergency Nurses Association, National Association of Emergency Medical Services Physicians, and National Association of Emergency Medical Technicians on pediatric readiness in emergency medical services...
journal_title:Pediatrics
pub_type: 指南,杂志文章
doi:10.1542/peds.2019-3307
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:Antimicrobial treatment may disturb the colonization resistance of gastrointestinal microflora, which may induce clinical symptoms, most commonly diarrhea. The severity of antibiotic-associated diarrhea may range from a brief, self-limiting disease to devastating diarrhea with electrolyte disturbances, dehyd...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1542/peds.104.5.e64
更新日期:1999-11-01 00:00:00
abstract::A 9-year-old black girl with vertically acquired human immunodeficiency virus (HIV) and no history of condyloma acuminata presented with a 4-year history of enlarging and spreading dark brown flat papules in the perineum. Some of the lesions were confluent and extended from the clitoris to the labia majora and posteri...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.112.1.e73
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVES:The association between parent-reported postnatal secondhand tobacco smoke exposure in the home and neurobehavioral disorders (attention-deficit/hyperactivity disorder, learning disabilities, and conduct disorders) among children younger than 12 years in the United States was examined using the 2007 National...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-0023
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:Increased physical activity and menstrual irregularity have been associated with increased risk for stress fracture among adult women active in athletics. The purposes of this study were to determine whether menstrual irregularity is also a risk factor for stress fracture in active female adolescents and to e...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-2145
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Adults born preterm score lower on performance-based tests of executive functioning (EF) than their term-born peers. These test scores do not necessarily translate to application of these skills in an everyday environment. The objective of the study was to test differences between very low birt...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2012-0839
更新日期:2013-01-01 00:00:00
abstract::Plastic bronchitis is a condition in which large, bronchial casts with rubber-like consistency develop in the tracheobronchial tree and cause airway obstruction. We describe a 4-year-old girl who had Fontan physiology and who developed plastic bronchitis and report for the first time the use of aerosolized tissue plas...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.109.4.e67
更新日期:2002-04-01 00:00:00
abstract::In 1977, 7% of the 38,855 infants born in Utah were estimated to have required a total of 27,439 special-care hospital days. About half (53%) were mildly ill; their average length of stay was 4.6 days, or 24% of the total hospital-days. Another 20% of the infants had intermediate illness, with a 12-day average stay, o...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1985-06-01 00:00:00
abstract:OBJECTIVE:To determine the clinical role of inhaled nitric oxide (iNO) in the treatment of persistent pulmonary hypertension of the newborn (PPHN). STUDY DESIGN:Prospective open observational clinical study. SETTING:A regional cardiac and pediatric intensive care unit. METHODS:Twenty-five consecutive near-term neona...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract::Premature male infants have a higher incidence of respiratory distress syndrome (RDS) than female infants (male/female = 1.7:1.) With the demonstration that antenatal use of betamethasone significantly reduces the incidence of RDS, a proportional reduction or possibly a complete elimination of the discrepancy between ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1981-05-01 00:00:00