Abstract：
:The b-CAPSA I capsular polysaccharide vaccine for Haemophilus influenzae type b was given to 87,541 children 2 through 5 years of age in the Kaiser Permanente Medical Care Program, and the children were then followed using a multiple modality surveillance. Phase 1 consisted of 24-hour recall of immediate side effects which were recorded on questionnaires given to families of 13,500 children. Local side effects were found to be uncommon: 2.3% had a temperature of greater than or equal to 38.3 degrees C (greater than or equal to 101 degrees F); 4.8% had local erythema, 2.9% local swelling, and 12.6% local tenderness; two children had wheezing shortly after immunization. In Phase 2, 30 days after immunization, questionnaires were mailed to parents of all 87,541 children, who were asked to respond to questions about illnesses and health care. Phase 3 consisted of active surveillance of patient health care use by physicians and nurses during the 30 days after immunization. During the 30-day reporting periods, there were 40 hospitalizations, including one for wheezing and one for febrile seizure. Of the 40 hospitalizations, only the one for wheezing was believed by the admitting physician to be probably associated with vaccine administration. Three children had seizures within 30 days of immunization. None of the seizures was believed by the reporting physician to be associated with immunization. Adverse effects of the vaccine were mild, limited to local reactions and occasional temperature elevation; bronchospasm after immunization occurred rarely.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Black SB,Shinefield HRsubject
Has Abstractpub_date
1987-03-01 00:00:00pages
321-5issue
3eissn
0031-4005issn
1098-4275journal_volume
79pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract：:Data for this article, as in previous reports, are drawn principally from the Monthly Vital Statistics Report, published by the National Center for Health Statistics. The international data come from the Demographic Yearbook and the quarterly Population and Vital Statistics Report, both published by the Statistical Of...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1983-12-01 00:00:00
abstract：:The effects of a single dose of surfactant TA were assessed in premature neonates (birth weight 750 to 1749 g) with respiratory distress syndrome (RDS) in a multicenter, double-blind, randomized clinical trial. Only neonates with surfactant deficiency and without ultrasonographic evidence of intracranial hemorrhage gr...
journal_title：Pediatrics
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：1990-11-01 00:00:00
abstract：:A fatal myocardial infarction in a 22-year-old man with hemophilia A and a factor VIII inhibitor is described. The catastrophic event occurred while the patient was receiving high doses of unactivated prothrombin complex concentrates. Autopsy examination revealed myocardial hemorrhage with no evidence of coronary arte...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1984-08-01 00:00:00
abstract：OBJECTIVE:Adolescence is an important period of risk for the development of lifelong smoking behaviors. Compelling, although inconsistent, evidence suggests a relationship between parental smoking and the risk of smoking initiation during adolescence. This study investigates unresolved issues concerning the strength an...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.2008-2251
更新日期：2009-02-01 00:00:00
abstract：OBJECTIVE:To determine correlates of sedentary behaviors in adolescents through the examination of psychosocial and environmental variables. METHOD:The study used a cross-sectional design to evaluate an ethnically diverse clinic-based sample of 878 adolescents who were 11 to 15 years old. Bivariate and multivariate an...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.2004-1814
更新日期：2005-10-01 00:00:00
abstract：:The interval from the beginning of the Q wave to the origin of the T wave (Q-oTc interval) and total and ionized serum calcium levels were measured in 27 full-term and 77 premature infants. The correlation between Q-oTc and total and ionized calcium levels was significant in both full-term and normal premature infants...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1978-06-01 00:00:00
abstract：:Effects of phenylephrine hydrochloride on the degree of hypoxia were studied in six cyanotic patients with tetralogy of Fallot. Baseline aortic and right atrial oxygen saturations, blood gas tensions, pH, and indicator-dilution curves were obtained under stable conditions. Phenylephrine was infused while systemic arte...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1976-08-01 00:00:00
abstract：:The pharmacokinetics of chloramphenicol following intravenous and oral administration were studied in 14 infants with Haemophilus influenzae meningitis. Following five days of treatment with intravenous chloramphenicol (100 mg/kg/day every six hours), oral chloramphenicol was substituted at the same dose. Multiple ser...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1981-05-01 00:00:00
abstract：OBJECTIVE:Depression is common among adolescents, but rates increase significantly in the presence of chronic health conditions. Outpatient screening for depression is recommended but rarely formally conducted due to barriers of implementation. METHODS:To provide a model for depression screening of youth with chronic ...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.2013-0681
更新日期：2013-11-01 00:00:00
abstract：:On October 25, 2011, the Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention recommended that the quadrivalent human papillomavirus vaccine (Gardasil; Merck & Co, Inc, Whitehouse Station, NJ) be used routinely in males. The American Academy of Pediatrics has reviewed updated ...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.2011-3865
更新日期：2012-03-01 00:00:00
abstract：:A prospective, randomized, crossover trial was conducted comparing therapy with rifampin to therapy with ampicillin in eradicating Haemophilus influenzae type b carriage. Twenty-eight carriers were identified in a day care center following exposure to a patient with H influenzae type b meningitis; 26 children were ran...
journal_title：Pediatrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1980-07-01 00:00:00
abstract：:An overview is presented of the major methods of contraception available to the sexually active adolescent. Emphasis is given to the combined birth control pill, while the literature describing absolute and relative contraindications to oral contraception is reviewed. It is noted that adolescents with chronic illness ...
journal_title：Pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：1980-01-01 00:00:00
abstract：:Epigenetics, the study of functionally relevant chemical modifications to DNA that do not involve a change in the DNA nucleotide sequence, is at the interface between research and clinical medicine. Research on epigenetic marks, which regulate gene expression independently of the underlying genetic code, has dramatica...
journal_title：Pediatrics
pub_type： 杂志文章,评审
doi：10.1542/peds.2013-1032F
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVE:Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections is hypothesized to be a poststreptococcal autoimmune disorder. If clinical exacerbations are triggered by a streptococcal infection that activates cross-reacting antibodies against neuronal tissue or alters the production...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.2007-2658
更新日期：2008-06-01 00:00:00
abstract：:The unsaturated fatty acids that make up a large component of the lipid emulsion Intralipid are highly susceptible to peroxidation, and the products of this reaction could explain the toxicity that has been associated with the administration of some emulsions. Lipid peroxidation produces hydroperoxides, which can alte...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Three siblings with neonatal familial hyperparathyroidism diagnosed at age 4 months, 2 months, and 5 days, respectively, were treated. Hypercalciuria, nephrocalcinosis, and renal tubular acidosis were present in each child. In all three, there were higher responses of serum parathyroid hormone to serum calcium and hig...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1990-09-01 00:00:00
abstract：BACKGROUND:Treatment of primary nocturnal enuresis using 1-deamino-8-D-arginine-vasopressin is based on the hypothesis that antidiuretic hormone (arginine vasopressin [AVP]) secretion is insufficient during the night. Persisting doubts about the theoretical background of this treatment and first results pointing to a d...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.103.2.452
更新日期：1999-02-01 00:00:00
abstract：:Patients with cystic fibrosis are known to have pancreatic disorganization with associated pancreatic exocrine insufficiency. Endocrine hormonal secretion is also affected but diminution in insulin secretion is rarely accompanied by overt diabetes. We studied seven patients with cystic fibrosis to determine their carb...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1980-05-01 00:00:00
abstract：:The antibiotics trimethoprim (TMP) and sulfamethoxazole (SMZ), when used in combination, can cause metabolic acidosis, renal bicarbonate wasting, and growth failure. Retrospective review of repeated random serum chemistries from 10 children receiving TMP-SMZ and maintenance chemotherapy for acute lymphoid leukemia rev...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
abstract：OBJECTIVE:To investigate whether excessive television viewing throughout childhood and adolescence is associated with increased antisocial behavior in early adulthood. METHODS:We assessed a birth cohort of 1037 individuals born in Dunedin, New Zealand, in 1972-1973, at regular intervals from birth to age 26 years. We ...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.2012-1582
更新日期：2013-03-01 00:00:00
abstract：OBJECTIVE:Usage of computer resources at the point of care has a positive effect on physician decision making. Pediatricians' information-seeking behaviors are not well characterized. The goal of this study was to characterize quantitatively the information-seeking behaviors of general pediatricians and specifically co...
journal_title：Pediatrics
pub_type： 临床试验,杂志文章
doi：10.1542/peds.113.1.64
更新日期：2004-01-01 00:00:00
abstract：:An epidemic of acute myositis affecting children occurred in association with influenza B infections. The myositis followed the initial influenza-like episode, and almost exclusively involved the gastrocnemius and soleus muscles. Patients improved without specific treatment and made a complete recovery in four to five...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1976-02-01 00:00:00
abstract：:Nineteen children with rheumatic diseases refractory to standard treatment were given repeated large "pulses" of corticosteroid therapy. The pulses consisted of four repeated doses of 500 mg of hydrocortisone given intravenously over 20 to 30 minutes at six-hour intervals or of single intravenous injections of 30 mg/k...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1980-05-01 00:00:00
abstract：OBJECTIVE:To describe the prevalence of continuity of care over a 5-year period in a complete cohort of urban children universally insured for medical care provided under fee-for-service reimbursement. METHOD:All children enrolled in the study were born to women living in metropolitan Winnipeg between July 1, 1987 and...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：OBJECTIVE:A voluntary market withdrawal of orally administered, over-the-counter, infant cough and cold medications (CCMs) was announced in October 2007. The goal of this study was to assess CCM-related adverse events (AEs) among children after the withdrawal. METHODS:Emergency department (ED) visits for CCM-related A...
journal_title：Pediatrics
pub_type： 杂志文章,多中心研究
doi：10.1542/peds.2010-1839
更新日期：2010-12-01 00:00:00
abstract：OBJECTIVES:The objectives of this study were to: 1) determine the incidence of biphasic reactions in children with anaphylaxis; 2) establish what risk factors can predict progression to a biphasic reaction; and 3) assess the utility of inpatient observation for patients whose anaphylaxis appears to have resolved. METH...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.106.4.762
更新日期：2000-10-01 00:00:00
abstract：:In a previously described population of 314 autistic and 237 dysphasic nonautistic children, after exclusion of 12 autistic girls with Rett syndrome, 14% (42 of 302) of autistic children and 8% (19 of 237) of dysphasic children had epilepsy (P = .03). The major risk factors for epilepsy were severe mental deficiency a...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-12-01 00:00:00
abstract：:Therapeutic moderate hypothermia in newborns with hypoxic-ischemic encephalopathy is rapidly becoming standard clinical practice. We report here 12 cases of subcutaneous fat necrosis among 1239 cases registered with a national registry of newborns treated with moderate whole-body hypothermia. All the infants suffered ...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.2010-3508
更新日期：2011-08-01 00:00:00
abstract：:This statement updates the 1994 American Academy of Pediatrics policy statement on baseball and softball injuries in children. Current studies on acute, overuse, and catastrophic injuries are reviewed with emphasis on the causes and mechanisms of injury. This information serves as a basis for recommending safe trainin...
journal_title：Pediatrics
pub_type： 指南,杂志文章
doi：10.1542/peds.107.4.782
更新日期：2001-04-01 00:00:00
abstract：:Data from 442 children, aged 2 to 5, who were participants in the 1987-1988 Nationwide Food Consumption Survey, were examined to determine the effect of maternal employment on the quality of their diets. Diet quality was assessed by examining nutrient adequacy and nutrient overconsumption using the 3-day average of on...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-08-01 00:00:00
