Fatal hepatitis B in early infancy: the importance of identifying HBsAg-positive pregnant women and providing immunoprophylaxis to their newborns.

Abstract:

:Infants born to women who are asymptomatic hepatitis B surface antigen (HBsAg) carriers frequently acquire hepatitis B virus infection in infancy. The spectrum of disease in such affected infants includes mild transient acute hepatitis B, chronic active hepatitis with or without cirrhosis, chronic persistent hepatitis, chronic asymptomatic HBsAg carriage, and, rarely, fulminant fatal hepatitis B. Recently, the administration of hepatitis B immunoglobulin has been demonstrated to reduce the risk of infantile acquisition of hepatitis B virus; hepatitis B vaccine may also be preventive in this setting. Three young infants, aged 8 to 16 weeks, who died of acute fulminant hepatitis were studied. In each instance, the mother was found, retrospectively, to be asymptomatic but HBsAg positive. One of these mothers was hepatitis B e-antigen-negative but hepatitis B e-antibody positive. All three babies were HBsAg positive; two who were tested for hepatitis B core antibody were positive. These three fatalities serve to dramatize both the importance of HBsAg screening of pregnant women, particularly those with demographic factors that place them at increased risk for HBsAg carriage, as well as the significance of effective immunoprophylaxis for hepatitis B in all offspring of women with HBsAg seropositivity.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Delaplane D,Yogev R,Crussi F,Shulman ST

subject

Has Abstract

pub_date

1983-08-01 00:00:00

pages

176-80

issue

2

eissn

0031-4005

issn

1098-4275

journal_volume

72

pub_type

杂志文章
  • A residential summer camp for children with vertically transmitted HIV/AIDS: a six-year experience at the Hole in the Wall Gang Camp.

    abstract::Residential camping sessions for children with vertically transmitted human immunodeficiency virus/acquired immunodeficiency syndrome have been offered at The Hole In The Wall Gang Camp for the past six summers. More than 600 children 6 to 12 years of age have attended. Such sessions are expensive and require extensiv...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.100.4.709

    authors: Pearson HA,Johnson S,Simpson BJ,Gallagher M

    更新日期:1997-10-01 00:00:00

  • Respiratory Management of the Patient With Duchenne Muscular Dystrophy.

    abstract::In 2010, Care Considerations for Duchenne Muscular Dystrophy, sponsored by the Centers for Disease Control and Prevention, was published in Lancet Neurology, and in 2018, these guidelines were updated. Since the publication of the first set of guidelines, survival of individuals with Duchenne muscular dystrophy has in...

    journal_title:Pediatrics

    pub_type: 杂志文章,实务指引

    doi:10.1542/peds.2018-0333H

    authors: Sheehan DW,Birnkrant DJ,Benditt JO,Eagle M,Finder JD,Kissel J,Kravitz RM,Sawnani H,Shell R,Sussman MD,Wolfe LF

    更新日期:2018-10-01 00:00:00

  • Prolonged use of large intravenous steroid pulses in the rheumatic diseases of children.

    abstract::Nineteen children with rheumatic diseases refractory to standard treatment were given repeated large "pulses" of corticosteroid therapy. The pulses consisted of four repeated doses of 500 mg of hydrocortisone given intravenously over 20 to 30 minutes at six-hour intervals or of single intravenous injections of 30 mg/k...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Miller JJ 3rd

    更新日期:1980-05-01 00:00:00

  • Defining successful performance among pediatric residents.

    abstract::The pediatric literature has documented a growing attention to defining the nature and quality of residency training. The critical incident technique, a method widely accepted in industrial settings, was used in this study to determine attitudes and behaviors deemed critical for successful performance of residents in ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Altmaier EM,McGuinness G,Wood P,Ross RR,Bartley J,Smith W

    更新日期:1990-02-01 00:00:00

  • Outbreak of Mycoplasma pneumoniae-Associated Stevens-Johnson Syndrome.

    abstract:BACKGROUND:Stevens-Johnson syndrome (SJS) is an uncommon, sporadic disease and outbreaks are rare. In November 2013, an outbreak of SJS was identified at Children's Hospital Colorado. METHODS:Outbreak cases were children aged 5-21 with a discharge diagnosis of SJS admitted from September 1 to November 30, 2013. Medica...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2015-0278

    authors: Olson D,Watkins LK,Demirjian A,Lin X,Robinson CC,Pretty K,Benitez AJ,Winchell JM,Diaz MH,Miller LA,Foo TA,Mason MD,Lauper UL,Kupfer O,Kennedy J,Glodé MP,Kutty PK,Dominguez SR

    更新日期:2015-08-01 00:00:00

  • Effects of polychlorinated biphenyl/dioxin exposure and feeding type on infants' mental and psychomotor development.

    abstract:OBJECTIVE:To evaluate the effects of in utero and lactational exposure to polychlorinated biphenyls (PCBs) and dioxins on the mental and psychomotor development of infants. DESIGN:Prenatal PCB exposure was estimated from the levels in maternal plasma during the last month of pregnancy. Postnatal PCB and dioxin exposur...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Koopman-Esseboom C,Weisglas-Kuperus N,de Ridder MA,Van der Paauw CG,Tuinstra LG,Sauer PJ

    更新日期:1996-05-01 00:00:00

  • Tone and reflex development before term.

    abstract::The evolution of tone and reflexes from 25 weeks postmenstrual age (gestational age plus chronologic age) to term in a population of 42 surviving infants is described. The infants were born in 1983 at the Johns Hopkins Hospital, had birth weights less than 1300 g, were examined weekly until neonatal intensive care uni...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Allen MC,Capute AJ

    更新日期:1990-03-01 00:00:00

  • Cognitive function and brain structure in females with a history of adolescent-onset anorexia nervosa.

    abstract:OBJECTIVE:Abnormalities in cognitive function and brain structure have been reported in acutely ill adolescents with anorexia nervosa, but whether these abnormalities persist or are reversible in the context of weight restoration remains unclear. Brain structure and cognitive function in female subjects with adolescent...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-0170

    authors: Chui HT,Christensen BK,Zipursky RB,Richards BA,Hanratty MK,Kabani NJ,Mikulis DJ,Katzman DK

    更新日期:2008-08-01 00:00:00

  • Hyperbilirubinemia in low birth weight infants and outcome at 5 years of age.

    abstract::The collaborative national survey on morbidity and mortality in preterm and small for gestational age infants in the Netherlands enrolled initially 1338 infants born in 1983. The relationship between maximal serum total bilirubin concentration in the neonatal period and neurodevelopmental outcome in the survivors of t...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: van de Bor M,Ens-Dokkum M,Schreuder AM,Veen S,Brand R,Verloove-Vanhorick SP

    更新日期:1992-03-01 00:00:00

  • Long eyelashes in a case series of 93 children with vernal keratoconjunctivitis.

    abstract:OBJECTIVE:Vernal keratoconjunctivitis (VKC) is a chronic conjunctivitis that affects children mainly in temperate areas, with exacerbations in spring and summer. Eyelashes provide natural protection for the eyes from sunshine, wind, and foreign bodies. These factors induce a worsening of signs and symptoms in VKC, wher...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-1555

    authors: Pucci N,Novembre E,Lombardi E,Massai C,Bernardini R,Caputo R,Campa L,de Libero C,Vierucci A

    更新日期:2005-01-01 00:00:00

  • Relief of pain and anxiety in pediatric patients in emergency medical systems.

    abstract::Whether a component of a disease process, the result of acute injury, or a product of a diagnostic or therapeutic procedure, pain should be relieved and stress should be decreased for pediatric patients. Control of pain and stress for children who enter into the emergency medical system, from the prehospital arena to ...

    journal_title:Pediatrics

    pub_type: 指南,杂志文章,实务指引

    doi:10.1542/peds.2004-1752

    authors: Zempsky WT,Cravero JP,American Academy of Pediatrics Committee on Pediatric Emergency Medicine and Section on Anesthesiology and Pain Medicine.

    更新日期:2004-11-01 00:00:00

  • Milk production by mothers of premature infants.

    abstract::Milk volume, day of initiation of pumping, duration and frequency of milk expression, and length of night rest interval were evaluated for the first month postpartum in 32 healthy, nonsmoking women (ages 20 to 38 years) who delivered at 28 to 30 weeks' gestation. Early milk volumes were related negatively to the delay...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Hopkinson JM,Schanler RJ,Garza C

    更新日期:1988-06-01 00:00:00

  • Cutaneous involvement in children with acute lymphoblastic leukemia or lymphoblastic lymphoma. The Children's Leukemia Cooperative Group of the European Organization of Research and Treatment of Cancer (EORTC).

    abstract:OBJECTIVE:Skin involvement in children with acute monocytic leukemia or CD30-positive anaplastic large-cell lymphoma is well-known. In contrast, very little is known about the malignant cutaneous infiltrates in children with acute lymphoblatic leukemia (ALL) or lymphoblastic lymphoma (LBL). This study was designed to d...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.100.1.60

    authors: Millot F,Robert A,Bertrand Y,Mechinaud F,Laureys G,Ferster A,Brock P,Rohrlich P,Mazingue F,Plantaz D,Plouvier E,Pacquement H,Behar C,Rialland X,Chantraine JM,Guilhot F,Otten J

    更新日期:1997-07-01 00:00:00

  • Long-term outcomes of infant behavioral dysregulation.

    abstract:OBJECTIVES:To determine whether maternal report of infant behavioral dysregulation at 6 months is associated with a higher prevalence of behavioral concerns at 5, 14, and 21 years of age; and to assess the extent to which maternal and social factors may affect reported child behavior outcomes. METHODS:From the Mater-U...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-3517

    authors: Hyde R,O'Callaghan MJ,Bor W,Williams GM,Najman JM

    更新日期:2012-11-01 00:00:00

  • Smoking in the movies increases adolescent smoking: a review.

    abstract:OBJECTIVE:Despite voluntary restrictions prohibiting direct and indirect cigarette marketing to youth and paid product placement, tobacco use remains prevalent in movies. This article presents a systematic review of the evidence on the nature and effect of smoking in the movies on adolescents (and others). METHODOLOGY...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2005-0141

    authors: Charlesworth A,Glantz SA

    更新日期:2005-12-01 00:00:00

  • Principles of Child Health Care Financing.

    abstract::After passage of the Patient Protection and Affordable Care Act, more children and young adults have become insured and have benefited from health care coverage than at any time since the creation of the Medicaid program in 1965. From 2009 to 2015, the uninsurance rate for children younger than 19 years fell from 9.7%...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2017-2098

    authors: Hudak ML,Helm ME,White PH,COMMITTEE ON CHILD HEALTH FINANCING.

    更新日期:2017-09-01 00:00:00

  • Nocturnal arterial oxygen saturation and academic performance in a community sample of children.

    abstract:OBJECTIVE:Hypoxemia, often assessed via pulse oximetry, is associated with neurocognitive deficits in children. The best way to qualify hypoxemia, or which level of hypoxemia already affects cognition, is unknown. METHODS:We assessed the association of pulse oximetry-derived variables that qualify hypoxemia with impai...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-1256

    authors: Urschitz MS,Wolff J,Sokollik C,Eggebrecht E,Urschitz-Duprat PM,Schlaud M,Poets CF

    更新日期:2005-02-01 00:00:00

  • Identifying the Misshapen Head: Craniosynostosis and Related Disorders.

    abstract::Pediatric care providers, pediatricians, pediatric subspecialty physicians, and other health care providers should be able to recognize children with abnormal head shapes that occur as a result of both synostotic and deformational processes. The purpose of this clinical report is to review the characteristic head shap...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2020-015511

    authors: Dias MS,Samson T,Rizk EB,Governale LS,Richtsmeier JT,SECTION ON NEUROLOGIC SURGERY, SECTION ON PLASTIC AND RECONSTRUCTIVE SURGERY.

    更新日期:2020-09-01 00:00:00

  • Self-reported physician practices for children with asthma: are national guidelines followed?

    abstract:OBJECTIVE:To determine self-reported adherence to national asthma guidelines for children by primary care physicians in managed care; and, to analyze sources of variation in these practices by physician specialty and managed care practice type. DESIGN:A survey of 671 primary care physicians (pediatricians and family p...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Finkelstein JA,Lozano P,Shulruff R,Inui TS,Soumerai SB,Ng M,Weiss KB

    更新日期:2000-10-01 00:00:00

  • The epidemiology of Staphylococcus aureus in a newborn nursery from 1970 through 1976.

    abstract::Results of seven years of epidemiologic surveillance for Staphylococcus aureus in a newborn nursery are presented as a follow-up of a study from this same institution published in 1969. Surveillance of the previous study included years 1961 through 1968. A continued rise in S. aureus colonization rates among newborns ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Hargiss C,Larson E

    更新日期:1978-03-01 00:00:00

  • Microbiology of the vagina in children: normal and potentially pathogenic organisms.

    abstract::Vaginal cultures from 100 healthy girls, 2 months to 15 years of age, were examined for the presence of normal and potentially pathogenic microorganisms. Corynebacterium vaginale, yeast species, and genital mycoplasmas were isolated from vaginal cultures from 13.5 %, 28%, and 28% of the girls examined, respectively. C...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Hammerschlag MR,Alpert S,Rosner I,Thurston P,Semine D,McComb D,McCormack WM

    更新日期:1978-07-01 00:00:00

  • Comparison of cefpodoxime proxetil and cefixime in the treatment of acute otitis media in infants and children. Otitis Study Group.

    abstract:OBJECTIVE:To compare the use of once-a-day cefpodoxime proxetil to once-a-day cefixime in the treatment of acute suppurative otitis media. DESIGN:Randomized, multicenter, investigator-blinded. SETTING:Outpatient. PATIENTS:A total of 368 patients (age 2 months to 17 years) were randomized to receive either cefpodoxim...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Asmar BI,Dajani AS,Del Beccaro MA,Mendelman PM

    更新日期:1994-12-01 00:00:00

  • US National Longitudinal Lesbian Family Study: psychological adjustment of 17-year-old adolescents.

    abstract:OBJECTIVES:The objective of this study was to document the psychological adjustment of adolescents who were conceived through donor insemination by lesbian mothers who enrolled before these offspring were born in the largest, longest running, prospective, longitudinal study of same-sex-parented families. METHODS:Betwe...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2009-3153

    authors: Gartrell N,Bos H

    更新日期:2010-07-01 00:00:00

  • Factors that influence receipt of recommended preventive pediatric health and dental care.

    abstract:OBJECTIVE:This study examined the factors that affect children's receipt of recommended well-child and dental visits using nationally representative data. METHODS:We analyzed the Child Public Use File of the 1999 National Survey of America's Families, including 35 938 children who were younger than 18 years. Bivariate...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.110.6.e73

    authors: Yu SM,Bellamy HA,Kogan MD,Dunbar JL,Schwalberg RH,Schuster MA

    更新日期:2002-12-01 00:00:00

  • Verapamil: an effective calcium blocking agent for pediatric patients.

    abstract::Verapamil is a slow-channel calcium-blocking agent that has been released recently by the Food and Drug Administration for treatment of cardiac dysrhythmias in all age groups. Its primary action is to slow conduction in the atrioventricular node, thereby abolishing those types of supraventricular tachycardia using the...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:

    authors: Porter CJ,Garson A Jr,Gillette PC

    更新日期:1983-05-01 00:00:00

  • Obesity and Mortality Risk in Critically Ill Children.

    abstract:BACKGROUND AND OBJECTIVES:Childhood obesity is epidemic and may be associated with PICU mortality. Using a large multicenter PICU database, we investigated the association between obesity and PICU mortality, adjusting for initial severity of illness. We further investigated whether height- and weight-based classificati...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2015-2035

    authors: Ross PA,Newth CJ,Leung D,Wetzel RC,Khemani RG

    更新日期:2016-03-01 00:00:00

  • Chronic Conditions and Health Care Needs of Adolescents Born at 23 to 25 Weeks' Gestation.

    abstract:OBJECTIVE:We examined chronic conditions, functional limitations, and special health care needs in extremely preterm children (EPT; 23-25 weeks' gestation) born between 1992 and 1998 at 2 Swedish tertiary care centers that offered regional and active perinatal care to all live-born EPT infants. METHODS:Of 134 survivin...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2016-2215

    authors: Holsti A,Adamsson M,Hägglöf B,Farooqi A,Serenius F

    更新日期:2017-02-01 00:00:00

  • Quality of evidence-based pediatric guidelines.

    abstract:OBJECTIVE:To identify evidence-based pediatric guidelines and to assess their quality. METHODS:We searched Medline, Embase, and relevant Web sites of guideline development programs and national pediatric societies to identify evidence-based pediatric guidelines. A list with titles of identified guidelines was sent to ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-0575

    authors: Boluyt N,Lincke CR,Offringa M

    更新日期:2005-05-01 00:00:00

  • Reducing distress in mothers of children with autism and other disabilities: a randomized trial.

    abstract:BACKGROUND:Compared with other parents, mothers of children with autism spectrum disorder or other neurodevelopmental disabilities experience more stress, illness, and psychiatric problems. Although the cumulative stress and disease burden of these mothers is exceptionally high, and associated with poorer outcomes in c...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2013-3164

    authors: Dykens EM,Fisher MH,Taylor JL,Lambert W,Miodrag N

    更新日期:2014-08-01 00:00:00

  • Prenatal Exposure to Acetaminophen and Risk of ADHD.

    abstract:OBJECTIVES:To estimate the association between maternal use of acetaminophen during pregnancy and of paternal use before pregnancy with attention-deficit/hyperactivity disorder (ADHD) in offspring while adjusting for familial risk for ADHD and indications of acetaminophen use. METHODS:Diagnoses were obtained from the ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2016-3840

    authors: Ystrom E,Gustavson K,Brandlistuen RE,Knudsen GP,Magnus P,Susser E,Davey Smith G,Stoltenberg C,Surén P,Håberg SE,Hornig M,Lipkin WI,Nordeng H,Reichborn-Kjennerud T

    更新日期:2017-11-01 00:00:00