Nocturnal arterial oxygen saturation and academic performance in a community sample of children.

Abstract:

OBJECTIVE:Hypoxemia, often assessed via pulse oximetry, is associated with neurocognitive deficits in children. The best way to qualify hypoxemia, or which level of hypoxemia already affects cognition, is unknown. METHODS:We assessed the association of pulse oximetry-derived variables that qualify hypoxemia with impaired academic performance in mathematics in a population-based cross-section of 995 primary school children who underwent overnight home recordings of motion-resistant new-generation pulse oximeter saturation (SpO2). Impaired academic performance in mathematics was based on the last school report and defined as grade 4 to 6 on a 6-point scale (ie, approximately the lowest quintile grades). RESULTS:Of 10 variables under study, only the nadir of the SpO2 values was significantly associated with impaired performance. Categories of this variable representing mild (ie, 91%-93% SpO2; odds ratio: 1.65; 95% confidence interval: 1.06-2.56) and moderate hypoxemia (ie, < or =90% SpO2 ; odds ratio: 2.28; 95% confidence interval: 1.30-4.01) both were associated with impaired performance in mathematics. CONCLUSIONS:We suggest using the nadir of the SpO2 values in an overnight study to qualify hypoxemia in future studies. This variable may predict neurocognitive deficits in school children. Mild hypoxemia, as yet widely considered benign, may already affect cognition in childhood. SpO2

journal_name

Pediatrics

journal_title

Pediatrics

authors

Urschitz MS,Wolff J,Sokollik C,Eggebrecht E,Urschitz-Duprat PM,Schlaud M,Poets CF

doi

10.1542/peds.2004-1256

subject

Has Abstract

pub_date

2005-02-01 00:00:00

pages

e204-9

issue

2

eissn

0031-4005

issn

1098-4275

pii

peds.2004-1256

journal_volume

115

pub_type

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