The best-interest standard is not applied for neonatal resuscitation decisions.

Abstract:

OBJECTIVE:Legal and ethical standards require resuscitation when it is considered to be in the patient's best interest. We hypothesized that newborn infants might be dealt with according to different standards, compared with older patients. METHODS:An anonymous questionnaire describing 8 currently incompetent patients with potential neurologic sequelae who required resuscitation was administered to groups of physicians and students. Survival and morbidity rates were explicitly described; a very preterm infant, a full term infant and a 2-month-old infant had identical outcomes. Two patients, a 7-month-old infant and an 80-year-old patient, were previously significantly impaired. Respondents were asked whether resuscitation was in the patient's best interest and whether they would comply with the families' wishes if resuscitation was refused. RESULTS:There was an 85% response rate (n = 524). The largest proportions of respondents stated that it was in the best interests of the 2-month-old infant and the 7-year-old child to be resuscitated (97% and 94%, respectively), followed by the 50-year-old patient and the term infant (87%), the 2 patients with 5% chance of survival (76% and 80%), the premature infant (69%), and finally the 80-year-old patient (32%). Approximately one fifth of the respondents who thought that it was in a patient's best interests to be resuscitated would nevertheless accept the family's refusal of resuscitation for all scenarios except the 80-year-old patient (72% acceptance) and the preterm infant (54% acceptance). CONCLUSIONS:Whether resuscitation is considered in a patient's best interests is not closely related to survival rates or disability. Newborn infants and particularly preterm infants are systematically devalued, in comparison with older patients whose outcomes are the same or worse. Accepting a family's refusal of resuscitation, even among respondents who thought that resuscitation was in the patient's best interest, was much more common for the newborns.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Janvier A,Leblanc I,Barrington KJ

doi

10.1542/peds.2007-1520

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

963-9

issue

5

eissn

0031-4005

issn

1098-4275

pii

121/5/963

journal_volume

121

pub_type

杂志文章
  • Spermatic cord torsion: diagnostic limitations.

    abstract::To distinguish spermatic cord torsion from other intrascrotal pathology, scrotal ultrasound and radionuclide scanning have been highly recommended on the basis of both clinical and experimental studies. We review the data from six patients in whom ultrasound or nuclear medicine examination was misleading. We emphasize...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Stoller ML,Kogan BA,Hricak H

    更新日期:1985-12-01 00:00:00

  • Improving transition from pediatric to adult cystic fibrosis care: lessons from a national survey of current practices.

    abstract:OBJECTIVES:More than 500,000 adolescents with special health care needs age into adulthood each year in the United States, and there is growing recognition of the need for support of their transition to adult-oriented health care. Because of improved survival, cystic fibrosis has experienced this increasing transition ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-2217

    authors: McLaughlin SE,Diener-West M,Indurkhya A,Rubin H,Heckmann R,Boyle MP

    更新日期:2008-05-01 00:00:00

  • Clinical value of immunoglobulin A antitransglutaminase assay in the diagnosis of celiac disease.

    abstract:OBJECTIVES:Our goal was to evaluate the possible correspondence between antitissue transglutaminase of immunoglobulin A class levels and stage of mucosal damage in patients affected by celiac disease. In addition, we assessed clinical use of antitissue transglutaminase values to predict biopsy results. METHODS:One tho...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-0604

    authors: Diamanti A,Colistro F,Calce A,Devito R,Ferretti F,Minozzi A,Santoni A,Castro M

    更新日期:2006-12-01 00:00:00

  • Protection Versus Progress: The Challenge of Research on Cannabis Use During Pregnancy.

    abstract::A central tension in pediatric research ethics arises from our desire to protect children from harm while also allowing progress toward discoveries that could improve child health. A prime example of this tension is research on a controversial yet increasingly common practice: the use of cannabis by women to treat nau...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2020-0818R

    authors: MacDuffie KE,Kleinhans NM,Stout K,Wilfond BS

    更新日期:2020-08-01 00:00:00

  • Kwashiorkor in the United States.

    abstract::Kwashiorkor, with typical edema and skin rash is occasionally seen in affluent countries as a result of severe protein restriction. Treatment is with a lactose-free formula after rehydration and sometimes after a period of parenteral alimentation. Complications of therapy included: diarrhea, congestive heart failure, ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Chase HP,Kumar V,Caldwell RT,O'Brien D

    更新日期:1980-12-01 00:00:00

  • Four patterns of response to inhaled nitric oxide for persistent pulmonary hypertension of the newborn.

    abstract:OBJECTIVE:To determine the clinical role of inhaled nitric oxide (iNO) in the treatment of persistent pulmonary hypertension of the newborn (PPHN). STUDY DESIGN:Prospective open observational clinical study. SETTING:A regional cardiac and pediatric intensive care unit. METHODS:Twenty-five consecutive near-term neona...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章

    doi:

    authors: Goldman AP,Tasker RC,Haworth SG,Sigston PE,Macrae DJ

    更新日期:1996-10-01 00:00:00

  • Maternal characteristics and perception of temperament associated with infant TV exposure.

    abstract:OBJECTIVE:This study examines the development of television (TV) behaviors across the first 18 months of life and identifies maternal and infant predictors of infant TV exposure. METHODS:We used longitudinal TV exposure, maternal sociodemographic, and infant temperament data from 217 African-American mother-infant pai...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2012-1224

    authors: Thompson AL,Adair LS,Bentley ME

    更新日期:2013-02-01 00:00:00

  • Evaluation of New York State's Child Health Plus: children who have asthma.

    abstract:BACKGROUND:Little is known about the impact of providing health insurance to uninsured children who have asthma or other chronic diseases. OBJECTIVES:To evaluate the association between health insurance and the utilization of health care and the quality of care among children who have asthma. DESIGN:Before-and-during...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Szilagyi PG,Holl JL,Rodewald LE,Yoos L,Zwanziger J,Shone LP,Mukamel DB,Trafton S,Dick AW,Raubertas RF

    更新日期:2000-03-01 00:00:00

  • Successful use of plasma exchange for profound hemolysis in a child with loxoscelism.

    abstract::We describe a 6-year-old boy who presented with massive hemolysis, shock, disseminated intravascular coagulopathy, and acute renal failure after loxosceles envenomation. In this patient, plasma exchange therapy (PEX) successfully cleared the plasma from an initial hemolytic index of 2000 (equivalent to 2 g/dL hemoglob...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2013-3338

    authors: Said A,Hmiel P,Goldsmith M,Dietzen D,Hartman ME

    更新日期:2014-11-01 00:00:00

  • Ethnic differences in the presence of secondary sex characteristics and menarche among US girls: the Third National Health and Nutrition Examination Survey, 1988-1994.

    abstract:OBJECTIVE:To assess measures of puberty-presence of pubic hair, breast development, and menarche-for 3 racial/ethnic groups of girls in the United States. METHODS:Using data from the Third National Health and Nutrition Examination Survey, this study sample was restricted to 1623 girls aged 8 to 16 years (466 non-Hispa...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.110.4.752

    authors: Wu T,Mendola P,Buck GM

    更新日期:2002-10-01 00:00:00

  • Preventing abusive head trauma among infants and young children: a hospital-based, parent education program.

    abstract:OBJECTIVE:Abusive head injuries among infants (shaken infant or shaken impact syndrome) represent a devastating form of child abuse; an effective prevention program that reduces the incidence of abusive head injuries could save both lives and the costs of caring for victims. We wished to determine whether a comprehensi...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1542/peds.2004-1896

    authors: Dias MS,Smith K,DeGuehery K,Mazur P,Li V,Shaffer ML

    更新日期:2005-04-01 00:00:00

  • Standardizing the Evaluation of Nonaccidental Trauma in a Large Pediatric Emergency Department.

    abstract:BACKGROUND AND OBJECTIVES:Variability exists in the evaluation of nonaccidental trauma (NAT) in the pediatric emergency department because of misconceptions and individual bias of clinicians. Further maltreatment, injury, and death can ensue if these children are not evaluated appropriately. The implementation of guide...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2017-1994

    authors: Riney LC,Frey TM,Fain ET,Duma EM,Bennett BL,Murtagh Kurowski E

    更新日期:2018-01-01 00:00:00

  • Obesity at the onset of diabetes in an ethnically diverse population of children: what does it mean for epidemiologists and clinicians?

    abstract:OBJECTIVE:It is often difficult to determine the pathophysiology of childhood diabetes at onset, particularly in overweight children, because obesity has been associated with both type 1 and type 2 diabetes. We compared children at the diagnosis of diabetes in a multiethnic population-based registry to understand the e...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-1448

    authors: Lipton RB,Drum M,Burnet D,Rich B,Cooper A,Baumann E,Hagopian W

    更新日期:2005-05-01 00:00:00

  • Skin lesions in association with beta-hemolytic Streptococcus group B.

    abstract::A full-term male infant delivered by caesarean section following a prolonged rupture of the amniotic membranes of 30 hours' duration manifested peculiar skin lesions at the time of birth consistent with the healing phase of bullous impetigo. He was colonized with beta-hemolytic Streptococcus group B that was also cult...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Lopez JB,Gross P,Boggs TR

    更新日期:1976-12-01 00:00:00

  • Management of Neonates Born to Mothers With Graves' Disease.

    abstract::Neonates born to mothers with Graves' disease are at risk for significant morbidity and mortality and need to be appropriately identified and managed. Because no consensus guidelines regarding the treatment of these newborns exist, we sought to generate a literature-based management algorithm. The suggestions include ...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2015-1878

    authors: van der Kaay DC,Wasserman JD,Palmert MR

    更新日期:2016-04-01 00:00:00

  • Dietary fiber in weaning foods of young children.

    abstract:OBJECTIVE:An evaluation of the opportunity to introduce fiber in the diet of weaning infants. METHODS:A descriptive review of the literature to assess the role of fiber in the following dietary interventions: (1) definition of the nutrient amounts that meet the weaning infant's physiologic needs; (2) modulation of dig...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:

    authors: Agostoni C,Riva E,Giovannini M

    更新日期:1995-11-01 00:00:00

  • Long-term follow-up and outcome of phenylketonuria patients on sapropterin: a retrospective study.

    abstract:OBJECTIVE:Sapropterin dihydrochloride, the synthetic form of 6R-tetrahydrobiopterin (BH4), is an approved drug for the treatment of patients with BH4-responsive phenylketonuria (PKU). The purpose of this study was to assess genotypes and data on the long-term effects of BH4/sapropterin on metabolic control and patient-...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2012-3291

    authors: Keil S,Anjema K,van Spronsen FJ,Lambruschini N,Burlina A,Bélanger-Quintana A,Couce ML,Feillet F,Cerone R,Lotz-Havla AS,Muntau AC,Bosch AM,Meli CA,Billette de Villemeur T,Kern I,Riva E,Giovannini M,Damaj L,Leuzzi V,B

    更新日期:2013-06-01 00:00:00

  • The Revised WIC Food Package and Child Development: A Quasi-Experimental Study.

    abstract:BACKGROUND AND OBJECTIVES:The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC), one of the largest US safety net programs, was revised in 2009 to be more congruent with dietary guidelines. We hypothesize that this revision led to improvements in child development. METHODS:Data were drawn f...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2020-1853

    authors: Guan A,Hamad R,Batra A,Bush NR,Tylavsky FA,LeWinn KZ

    更新日期:2021-02-01 00:00:00

  • High-risk periods for childhood injury among siblings.

    abstract:OBJECTIVE:To determine whether the risk of unintentional injury requiring emergency department (ED) or inpatient care in children is transiently increased over a 90-day period after injury to a sibling. DESIGN:Retrospective cohort. SETTING:King County, Washington. Participants. A total of 41 242 children 0 to 15 year...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.105.3.562

    authors: Johnston BD,Grossman DC,Connell FA,Koepsell TD

    更新日期:2000-03-01 00:00:00

  • Which children benefit the most from early intervention?

    abstract::Recent findings from three separate studies support and extend a large and growing body of early-intervention research literature spanning 30 years. The literature is consistent in demonstrating positive developmental outcomes as a result of intensive early intervention for children of low-income and undereducated fam...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Ramey CT,Ramey SL

    更新日期:1994-12-01 00:00:00

  • Maternal Depression in Early Childhood and Developmental Vulnerability at School Entry.

    abstract:OBJECTIVES:To assess the relation between exposure to maternal depression before age 5 and 5 domains of developmental vulnerability at school entry, overall, and by age at exposure. METHODS:This cohort study included all children born in Manitoba, Canada, who completed the Early Development Instrument between 2005 and...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2020-0794

    authors: Wall-Wieler E,Roos LL,Gotlib IH

    更新日期:2020-09-01 00:00:00

  • Food intakes of US children and adolescents compared with recommendations.

    abstract:OBJECTIVES:To determine the proportion of youth meeting national recommendations for food group intake and to identify food intake patterns. DESIGN:The US Department of Agriculture's 1989-1991 Continuing Surveys of Food Intakes by Individuals were used to estimate food intake. Intake was determined from 3 days of diet...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.100.3.323

    authors: Muñoz KA,Krebs-Smith SM,Ballard-Barbash R,Cleveland LE

    更新日期:1997-09-01 00:00:00

  • Tone and reflex development before term.

    abstract::The evolution of tone and reflexes from 25 weeks postmenstrual age (gestational age plus chronologic age) to term in a population of 42 surviving infants is described. The infants were born in 1983 at the Johns Hopkins Hospital, had birth weights less than 1300 g, were examined weekly until neonatal intensive care uni...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Allen MC,Capute AJ

    更新日期:1990-03-01 00:00:00

  • Are we overprescribing antireflux medications for infants with regurgitation?

    abstract:OBJECTIVE:Our goal was to evaluate the diagnosis and treatment of infants with persistent regurgitation who were referred to a pediatric gastroenterology service. METHODS:The records of 64 infants with persistent regurgitation and without any neurodevelopmental abnormalities, underlying illness, or cigarette smoke exp...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-1146

    authors: Khoshoo V,Edell D,Thompson A,Rubin M

    更新日期:2007-11-01 00:00:00

  • Improvement methodology increases guideline recommended blood cultures in children with pneumonia.

    abstract:BACKGROUND AND OBJECTIVE:A national evidence-based guideline for the management of community-acquired pneumonia (CAP) in children recommends blood cultures for patients admitted with moderate to severe illness. Our primary aim was to increase ordering of blood cultures for children hospitalized with CAP from 53% to 90%...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2014-2077

    authors: Murtagh Kurowski E,Shah SS,Thomson J,Statile A,Sheehan B,Iyer S,White C,Ambroggio L

    更新日期:2015-04-01 00:00:00

  • Prevalence of abusive injuries in siblings and household contacts of physically abused children.

    abstract:OBJECTIVE:Siblings and other children who share a home with a physically abused child are thought to be at high risk for abuse, but rates of injury in these contact children are unknown and screening of contacts is highly variable. Our objective was to determine the prevalence of abusive injuries identified by a common...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2012-0085

    authors: Lindberg DM,Shapiro RA,Laskey AL,Pallin DJ,Blood EA,Berger RP,ExSTRA Investigators.

    更新日期:2012-08-01 00:00:00

  • Cost-effectiveness analysis of bicycle helmet subsidies in a defined population.

    abstract:OBJECTIVE:To examine the potential effects of bicycle safety helmet cost subsidy on bicycle head injury rates and costs. DESIGN:Using empiric data on the incidence and costs of bicycle injuries to children, we examined the hypothetical effects of various bicycle helmet subsidies in a cost-effectiveness analysis. A hyp...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Thompson RS,Thompson DC,Rivara FP,Salazar AA

    更新日期:1993-05-01 00:00:00

  • Age, academic performance, and stimulant prescribing for ADHD: a nationwide cohort study.

    abstract:BACKGROUND:We evaluated whether younger age in class is associated with poorer academic performance and an increased risk of being prescribed stimulants for attention-deficit/hyperactivity disorder (ADHD). METHODS:This was a nationwide population-based cohort study, linking data from national registries of prescribed ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2012-0689

    authors: Zoëga H,Valdimarsdóttir UA,Hernández-Díaz S

    更新日期:2012-12-01 00:00:00

  • Genome-wide expression profiles in very low birth weight infants with neonatal sepsis.

    abstract:BACKGROUND:Bacterial sepsis is associated with high morbidity and mortality in preterm infants. However, diagnosis of sepsis and identification of the causative agent remains challenging. Our aim was to determine genome-wide expression profiles of very low birth weight (VLBW) infants with and without bacterial sepsis a...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2013-2552

    authors: Cernada M,Serna E,Bauerl C,Collado MC,Pérez-Martínez G,Vento M

    更新日期:2014-05-01 00:00:00

  • Quality-of-life concerns differ among patients, parents, and medical providers in children and adolescents with congenital and acquired heart disease.

    abstract:OBJECTIVES:Mortality rates in pediatric patients with heart disease have decreased dramatically in recent decades, resulting in an increasing number of survivors with morbidities that impact quality of life. The purpose of this study was to assess and compare how heart disease affects the quality of life of the pediatr...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-2572

    authors: Marino BS,Tomlinson RS,Drotar D,Claybon ES,Aguirre A,Ittenbach R,Welkom JS,Helfaer MA,Wernovsky G,Shea JA

    更新日期:2009-04-01 00:00:00