Approaches to optimize therapeutic bacteriophage and bacteriophage-derived products to combat bacterial infections.

abstract：:Porcine pegiviruses (PPgV) have been first discovered in serum samples from domestic pigs in Germany in 2016 and then in the USA in 2018. To date, there is no documentation with respect to the presence of PPgVs in domestic pigs in China. Herein, we attempted to determine the presence and prevalence of PPgV in China an...

journal_title：Virus genes

authors： Lei D,Ye Y,Lin K,Zhang F,Huang D,Li K,Yuan W,Wu Q,Ding Z,Wang L,Song D,Tang Y

更新日期：2019-04-01 00:00:00

abstract：:We evaluated the predicted biochemical properties of Gag proteins from a diverse group of feline immunodeficiency viruses (FIV) to determine how different evolutionary histories of virus and host have changed or constrained these important structural proteins. Our data are based on FIV sequences derived from domestic ...

journal_title：Virus genes

authors： Burkala E,Poss M

更新日期：2007-10-01 00:00:00

abstract：:The infection of humans with Boma disease virus (BDV) is still a matter of debate. In a recent publication, we described a BDV (RW98) isolated from the blood of a psychiatric patient. The RNA of this virus differed more than 5% from that of the widely used strain He/80, which was supposed to represent our laboratory v...

journal_title：Virus genes

authors： Planz O,Rziha HJ,Stitz L

更新日期：2003-01-01 00:00:00

abstract：:Orf virus (ORFV) strain D1701-V, a Parapoxvirus belonging to the family Poxviridae, became attractive as a novel virus vector system that we successfully used for the generation of recombinant vaccines. Therefore, the identification of viral genes involved in host tropisms or immune modulation is of great interest, as...

journal_title：Virus genes

authors： Lacek K,Bauer B,Bieńkowska-Szewczyk K,Rziha HJ

更新日期：2014-08-01 00:00:00

abstract：:Wild-type measles virus (wtMeV) adapted well to cotton rat lung (CRL) cells after serial passages. In order to evaluate the contributions of the individual genes of wtMeV for adaptation, whole genome sequences of the adapted and original viruses were determined and analyzed. The results showed that there were two muta...

journal_title：Virus genes

authors： Dong JB,Saito A,Mine Y,Sakuraba Y,Nibe K,Goto Y,Komase K,Nakayama T,Miyata H,Iwata H,Haga T

更新日期：2009-12-01 00:00:00

abstract：:Novel duck reovirus (NDRV), the prototype strain of the species Avian orthoreovirus (ARV), is associated with high mortality in Pekin ducklings. σC is an outer capsid protein encoded by the S1 genome segment of NDRV which mediates attachment to host cells. Our previous studies using immunoprecipitation and mass spectr...

journal_title：Virus genes

authors： Xiao R,Mi X,Sun J,Ding M,Li C,Zhu J,Liu G,Ma W,Zhou H,Chen Z

更新日期：2020-06-01 00:00:00

abstract：:We performed whole genome sequencing of 22 H9N2 avian influenza viruses (AIV) isolated from domestic laying hens on farms between 2005 and 2008, and compared the sequences with viruses previously reported in Asia. A previous study revealed that two antigenically distinct sublineages were established within the MS96 li...

journal_title：Virus genes

authors： Lee CH,Byun SH,Lee YJ,Mo IP

更新日期：2012-08-01 00:00:00

abstract：:The California 99 (Cal99) variant of infectious bronchitis virus (IBV) was first recovered in 1999 from vaccinated broiler chicken flocks in Central California. The S1 hypervariable region of Cal99 genome was most closely related to Arkansas (Ark) serotype viruses. In this study, the complete genome of Cal99 was seque...

journal_title：Virus genes

authors： Mondal SP,Cardona CJ

更新日期：2007-06-01 00:00:00

abstract：:Staphylococcus aureus is a well-known pathogen that causes several serious diseases in humans and animals. As part of the efforts to control this pathogen, a newly isolated bacteriophage, SA12, which specifically targets S. aureus, was characterized, and its genome was completely sequenced. Host range and bacteriophag...

journal_title：Virus genes

authors： Chang Y,Lee JH,Shin H,Heu S,Ryu S

更新日期：2013-10-01 00:00:00

abstract：:The complete genomic sequence of an isolate of Tobacco vein banding mosaic virus (TVBMV-YND) from Yunnan, China was determined by sequencing overlapping cDNA fragments obtained by RT-PCR with degenerate and/or specific primers. The genome is composed of 9,570 nucleotides (nt) excluding the 3'-terminal poly (A) tail an...

journal_title：Virus genes

authors： Yu XQ,Lan YF,Wang HY,Liu JL,Zhu XP,Valkonen JP,Li XD

更新日期：2007-12-01 00:00:00

abstract：:Exfoliative toxin A (ETA)-coding temperate bacteriophages are leading contributors to the toxic phenotype of impetigo strains of Staphylococcus aureus. Two distinct eta gene-positive bacteriophages isolated from S. aureus strains which recently caused massive outbreaks of pemphigus neonatorum in Czech maternity hospit...

journal_title：Virus genes

authors： Botka T,Růžičková V,Konečná H,Pantůček R,Rychlík I,Zdráhal Z,Petráš P,Doškař J

更新日期：2015-08-01 00:00:00

abstract：:Marek's disease (MD), a lymphoproliferative disease of chicken is caused by a highly cell-associated alpha-herpesvirus, Marek's disease virus (MDV). MDV replicates in chicken lymphocytes and establishes a latent infection within CD4(+) T cells. The expression analysis of limited viral transcripts have revealed differe...

journal_title：Virus genes

authors： Heidari M,Huebner M,Kireev D,Silva RF

更新日期：2008-04-01 00:00:00

abstract：:Nitric oxide (NO) has been shown to suppress Japanese encephalitis virus (JEV) RNA synthesis, viral protein accumulation, and virus release from infected cells. In this article, the potential viral structural proteins as the activators of NO product were studied at the molecular level. First, the genomic region encodi...

journal_title：Virus genes

authors： Chen SO,Fang SH,Shih DY,Chang TJ,Liu JJ

更新日期：2009-02-01 00:00:00

abstract：:The genomic structure of two strains of orf virus (OV), a field isolate (MRI-Scab) which has never been passaged in cell culture, and a multiple-passage cell culture-adapted strain (Orf-11) were compared. The Orf-11 genome is approximately 8.0 kb longer than that of the MRI-Scab due to a duplication of the right-hand ...

journal_title：Virus genes

authors： McInnes CJ,Wood AR,Nettleton PE,Gilray JA

更新日期：2001-03-01 00:00:00

abstract：:Porcine astrovirus (PAstV) belongs to genetically divergent lineages within the genus Mamastrovirus. In this study, 25/129 (19.4 %) domestic pig and 1/146 (0.7 %) wild boar fecal samples tested in South Korea were positive for PAstV. Positive samples were mainly from pigs under 6 weeks old. Bayesian inference (BI) tre...

journal_title：Virus genes

authors： Lee MH,Jeoung HY,Park HR,Lim JA,Song JY,An DJ

更新日期：2013-02-01 00:00:00

abstract：:Emerging pseudorabies virus (PRV) variant has led to frequent outbreaks of PRV infection among Bartha-K61-vaccinated swine population in Chinese swine farms and caused high mortality in pigs of all age since late 2011. Here, we generated a gE/gI-deleted PRV (rPRVXJ-delgI/gE-EGFP) based on PRV variant strain (PRV-XJ) t...

journal_title：Virus genes

authors： Yin Y,Xu Z,Liu X,Li P,Yang F,Zhao J,Fan Y,Sun X,Zhu L

更新日期：2017-08-01 00:00:00

abstract：:Geminiviridae consists of a large group of single-stranded DNA viruses that cause tremendous losses worldwide. Frequent mixed infection and high rates of recombination and mutation allow them to adapt rapidly to new hosts and overcome hosts' resistances. Therefore, an effective strategy able to confer plants with resi...

journal_title：Virus genes

authors： Chen W,Qian Y,Wu X,Sun Y,Wu X,Cheng X

更新日期：2014-06-01 00:00:00

abstract：:Serum samples collected from 88 Peruvians with unexplained fever were analyzed for viral sequences using metagenomics. Nucleic acids of anelloviruses, pegivirus A (GBV-C), HIV, Dengue virus, and Oropouche virus were detected. We also characterized from two sera the RNA genomes of new species of partitivirus and dicist...

journal_title：Virus genes

authors： Phan TG,Del Valle Mendoza J,Sadeghi M,Altan E,Deng X,Delwart E

更新日期：2018-02-01 00:00:00

abstract：:The thymidylate synthase (TS, EC 2.1.1.45) is essential for the de novo synthesis of dTMP in pro- and eucaryotic organisms. Consequently it plays a major role in the replication of the DNA genome of a cell or a DNA virus. The gene encoding the TS of Chilo iridescent virus (CIV) was identified by nucleotide sequence an...

journal_title：Virus genes

authors： Müller K,Tidona CA,Bahr U,Darai G

更新日期：1998-01-01 00:00:00

abstract：:Mal de Río Cuarto virus (MRCV) is a newly described species of the genus Fijivirus, family Reoviridae. Compared with other plant-infecting genus of the family, the function and localization of MRCV and other Fijivirus proteins are poorly understood. Through analysis of viral particle purifications, we positively ident...

journal_title：Virus genes

authors： Distéfano AJ,Maldonado S,Hopp HE,del Vas M

更新日期：2009-06-01 00:00:00

abstract：:Infectious full-length cDNA clones from the genomic RNAs of a subgroup II cucumber mosaic cucumovirus strain (Trk7) were obtained. Sequence analysis of the whole genome revealed strong homology (99%) to the genome of Q-CMV, the only subgroup II strain whose entire genomic nucleotide sequence had been available in the ...

journal_title：Virus genes

authors： Szilassy D,Salánki K,Balázs E

更新日期：1999-01-01 00:00:00

abstract：:Arenaviridae is a worldwide distributed family, of enveloped, single stranded, RNA viruses. The arenaviruses were divided in two major groups (Old World and New World), based on serological properties and genetic data, as well as the geographic distribution. In this study the phylogenetic relationship among the member...

journal_title：Virus genes

authors： Albariño CG,Posik DM,Ghiringhelli PD,Lozano ME,Romanowski V

更新日期：1998-01-01 00:00:00

abstract：:Newcastle disease viruses (NDV) isolated from pigeons (pigeon paramyxovirus type 1; PPMV-1) are mostly of mesogenic pathotype and characterized by a polybasic amino acid sequence motif at the fusion protein (F) cleavage site. This feature also applies to isolate R75/98 from Germany. Its genome consists of 15,192 nucle...

journal_title：Virus genes

authors： Heiden S,Grund C,Höper D,Mettenleiter TC,Römer-Oberdörfer A

更新日期：2014-12-01 00:00:00

abstract：:Orf virus (ORFV), a typical member of the Parapoxvirus genus within the family Poxviridae, which is the causative agent of Orf, a common epitheliotropic viral disease of sheep, goats, wild ruminants, and humans. In the present study, we sequenced the complete genomic sequences of two ORFV strains (ORFV-SY17, isolated ...

journal_title：Virus genes

authors： Zhong J,Guan J,Zhou Y,Cui S,Wang Z,Zhou S,Xu M,Wei X,Gao Y,Zhai S,Song D,He W,Gao F,Zhao K

更新日期：2019-08-01 00:00:00

abstract：:Despite the vast distribution and expansive diversity of enteroviruses reported globally, indicators defining a complete view of the epidemiology of enteroviruses in tropical countries such as the Philippines are yet to be established. Detection of enteroviruses in the environment has been one of the markers of circul...

journal_title：Virus genes

authors： Apostol LN,Imagawa T,Suzuki A,Masago Y,Lupisan S,Olveda R,Saito M,Omura T,Oshitani H

更新日期：2012-10-01 00:00:00

abstract：:A bovine viral diarrhea disease virus (BVDV) GS-4 was isolated in Western China form dairy cattle with respiratory disease. Genomic comparison analysis with the 5' half genome sequence encompassing the coding region of N(pro), capsid, and envelope glycoproteins showed that the GS-4 should be classified into BVDV-1b1, ...

journal_title：Virus genes

authors： Gao S,Shao J,Du J,Lin T,Cong G,Zhao F,Chang H,Yin H

更新日期：2013-08-01 00:00:00

abstract：:The Tahyna virus (TAHV) is an important human pathogen in the Bunyaviridae family. To date, only the S and M segments of this virus have been sequenced, but the sequence of the L segment hasn't been established yet. In this study, we sequenced 963 nucleotides of the L segment of TAHV, comprising pre-motif A and motif ...

journal_title：Virus genes

authors： Quinan BR,de Brito Magalhães CL,Novaes RF,Dos Santos JR,Kroon EG,Bonjardim CA,Ferreira PC

更新日期：2008-06-01 00:00:00

abstract：:Proteins harbor domains or short linear motifs, which facilitate their functions and interactions. Finding functional motifs in protein sequences could predict the putative cellular roles or characteristics of hypothetical proteins. In this study, we present Shetti-Motif, which is an interactive tool to (i) map UniPro...

journal_title：Virus genes

authors： Sobhy H

更新日期：2017-04-01 00:00:00

abstract：:Viroids, the smallest and simplest agents of infectious disease, cause a number of economically important diseases of crop plants. Present evidence indicates that most of these diseases originated recently (in the 20th century) by chance transfer of viroids from endemically infected wild plants or by use of viroid-inf...

journal_title：Virus genes

authors： Diener TO

更新日期：1995-01-01 00:00:00

abstract：:Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine skin cancer associated with the Merkel cell polyomavirus (MCPyV). The MCPyV genome, which is clonally integrated in the majority of MCCs, encodes the regulatory small T (sT) antigen. Previously, reports have established MCPyV sT antigen as a potent onco...

journal_title：Virus genes

authors： Wu JH,Simonette RA,Nguyen HP,Rady PL,Tyring SK

更新日期：2016-06-01 00:00:00