Abstract:
:Staphylococcus aureus is a well-known pathogen that causes several serious diseases in humans and animals. As part of the efforts to control this pathogen, a newly isolated bacteriophage, SA12, which specifically targets S. aureus, was characterized, and its genome was completely sequenced. Host range and bacteriophage challenge tests demonstrated its specific and efficient host lysis of S. aureus. The genome of phage SA12 consists of 42,902 bp length double-stranded DNA with 58 predicted ORFs-encoding phage structure, DNA manipulation, packaging, host lysis, and regulation proteins. The characterization and genome study of phage SA12 in this report is useful for understanding S. aureus-targeting bacteriophages and provides basic information for the further development of phage-based biocontrol agents against S. aureus.
journal_name
Virus Genesjournal_title
Virus genesauthors
Chang Y,Lee JH,Shin H,Heu S,Ryu Sdoi
10.1007/s11262-013-0938-7subject
Has Abstractpub_date
2013-10-01 00:00:00pages
389-93issue
2eissn
0920-8569issn
1572-994Xjournal_volume
47pub_type
杂志文章相关文献
VIRUS GENES文献大全abstract::White spot syndrome virus (WSSV) is one of the major pathogens of cultured shrimp. Identification of envelope protein interactions has become a central issue for the understanding of WSSV assembly. In this paper, WSSV envelope protein VP52B was fused with GST-tag and expressed in Escherichia coli BL-21(DE3). Immunogol...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-014-1126-0
更新日期:2015-02-01 00:00:00
abstract::The foot-and-mouth disease virus (FMDV) nonstructural protein 3A plays an important role in viral replication, virulence, and host range. It has been shown that deletions of 10 or 19-20 amino acids in the C-terminal half of 3A attenuate serotype O and C FMDVs, which replicate poorly in bovine cells but normally in por...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-017-1480-9
更新日期:2017-12-01 00:00:00
abstract::Porcine reproductive and respiratory syndrome (PRRS) is a swine disease of major economic importance that causes reproductive and respiratory problems in pigs. In the present study, one strain of porcine reproductive and respiratory syndrome virus (PRRSV) was isolated in Xinjiang province, Northwest China, designated ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-014-1122-4
更新日期:2015-02-01 00:00:00
abstract::Amino acid and phylogenetic analysis showed that PB1-F2 of H7N7 and H3N8 equine influenza virus (EIV) evolved into two and nine clades, respectively. The PB1-F2 gene of H7N7 EIV strains isolated after 1973 was identified as being replaced by that of H3N8 EIV circulating simultaneously. All H7N7 EIV strains before 1973...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-013-0935-x
更新日期:2013-10-01 00:00:00
abstract::Five spring viremia of carp viruses (SVCV), Rhabdovirus carpio, were isolated in the United States (US) between 2002 and 2004. Single tube reverse transcription-polymerase chain reaction (RT-PCR) was used to generate overlapping cDNA fragments from the US isolates of SVCV. Multiple pairs of specific primers were desig...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-006-0042-3
更新日期:2007-08-01 00:00:00
abstract::We evaluated the predicted biochemical properties of Gag proteins from a diverse group of feline immunodeficiency viruses (FIV) to determine how different evolutionary histories of virus and host have changed or constrained these important structural proteins. Our data are based on FIV sequences derived from domestic ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-006-0058-8
更新日期:2007-10-01 00:00:00
abstract::The nucleic acid and deduced amino acid sequence of the fibre gene of the HNF-61 strain of porcine adenovirus serotype 5 (PAdV-5) was determined and compared to that of the HNF-70 strain of the same serotype (Nagy et al., J Gen Virol 82, 525-529, 2001) and also to adenovirus fibre genes from the genera Mastadenovirus ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1023/a:1014580802250
更新日期:2002-03-01 00:00:00
abstract::The Agrotis ipsilon multiple nucleopolyhedrovirus (AgipMNPV) is a group II nucleopolyhedrovirus (NPV) from the black cutworm, A. ipsilon, with potential as a biopesticide to control infestations of cutworm larvae. The genome of the Illinois strain of AgipMNPV was completely sequenced. The AgipMNPV genome was 155,122 n...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-008-0297-y
更新日期:2009-02-01 00:00:00
abstract::E6 and E7 genes of human papilloma virus type 18 have been subcloned from plasmid pC7, carrying an insert of DNA from squamous cell carcinoma of cervix. Both genes in comparison to prototype variant contain one mutation that changes asparagine to leucine. In the case of E6 gene this mutation is mapped in codon 129, in...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1023/a:1008020719309
更新日期:1999-01-01 00:00:00
abstract::The establishment of viral pathogens in new host environments following spillover events probably requires adaptive changes within both the new host and pathogen. After many generations, signals for ancient cross-species transmission may become lost and a strictly host-adapted phylogeny may mimic true co-divergence wh...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-019-01702-x
更新日期:2019-12-01 00:00:00
abstract::Nine avian influenza viruses (AIV), H5N1 subtype, were isolated from dead poultry in the Karachi region of Pakistan from 2006 to 2008. The intravenous pathogenicity indices and HA protein cleavage sites of all nine viruses were consistent with highly pathogenic AIV. Based on phylogenetic analysis of the HA genes, thes...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-011-0689-2
更新日期:2012-04-01 00:00:00
abstract::H1 influenza A viruses that were distinct from the classical swine H1 lineage were identified in pigs in Canada in 2003–2004; antigenic and genetic characterization identified the hemagglutinin (HA) as human H1 lineage. The viruses identified in Canadian pigs were human lineage in entirety or double (human–swine) reas...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-009-0386-6
更新日期:2009-10-01 00:00:00
abstract::The early region 1A (E1A) gene of highly oncogenic adenovirus type 12 (Ad12) was analyzed for transforming activity and protein binding using specific mutations. The Ad12 E1A proteins were found to bind p300 protein mainly within the CR1 region, although mutations that affect both p300 binding and transformation were ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1023/a:1007967009156
更新日期:1997-01-01 00:00:00
abstract::The incidence of watermelon chlorotic stunt disease and the molecular characterization of the Jordanian isolate of Watermelon chlorotic stunt virus (WmCSV-[JO]) are described in this study. Symptomatic leaf samples obtained from watermelon (Citrullus lanatus Thunb.), melon (Cucumis melo L.), squash (Cucurbita pepo), c...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-011-0594-8
更新日期:2011-08-01 00:00:00
abstract::In this study, a novel duplex nanoparticle-assisted polymerase chain reaction (nanoPCR) assay was developed to detect porcine epidemic diarrhea virus (PEDV) and porcine transmissible gastroenteritis virus (TGEV). Two pairs of primers were designed based on the conserved region within the N gene of PEDV and TGEV. In a ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-016-1405-z
更新日期:2017-02-01 00:00:00
abstract::Influenza A viruses infect a range of host species, including various mammals and more than 100 species of birds. For avian influenza viruses (AIV), prevalence varies between different groups of birds, with waterfowl showing the highest prevalence. We have sequenced the complete genome of A/Thick-billed Murre/Newfound...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-010-0504-5
更新日期:2010-10-01 00:00:00
abstract::The immunity of a combined DNA vaccine of HSV-2 glycoproteins B2 (gB2) and D2 (gD2) genes in comparison to individual vaccines was studied with regard to protecting against the HSV infection. Two recombinant DNA vaccines of the pHS2-gB2 or pHS2-gD2 were constructed and formulated. The neutralizing antibody titers appe...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1023/a:1020113902834
更新日期:2002-10-01 00:00:00
abstract::Infection of infants in their first year of life, children and elderly people with the respiratory syncytial virus (RSV) endangers the life of the patient. An attempt to develop a formalin-inactivated RSV (FI-RSV) vaccine during the 1960s resulted in an aggravated infection in immunized children, leading to hospitaliz...
journal_title:Virus genes
pub_type: 杂志文章,评审
doi:10.1007/s11262-006-0064-x
更新日期:2006-10-01 00:00:00
abstract::Despite the vast distribution and expansive diversity of enteroviruses reported globally, indicators defining a complete view of the epidemiology of enteroviruses in tropical countries such as the Philippines are yet to be established. Detection of enteroviruses in the environment has been one of the markers of circul...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-012-0776-z
更新日期:2012-10-01 00:00:00
abstract::Herpesvirus saimiri induces acute lymphomas and leukemias in primates and rabbits. Sequence divergence of the right end unique region of the genome classifies virus strains into three groups (A, B, and C), and previous studies have demonstrated correlation between DNA grouping and oncogenicity. In order to relate diff...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/BF01703599
更新日期:1994-01-01 00:00:00
abstract::Base usage and dinucleotide frequency have been extensively studied in many eukaryotic organisms and bacteria, but not for viruses. In this paper, a comprehensive analysis of these aspects for infectious bursal disease virus (IBDV) was presented. The analysis of base usage indicated that all of the IBDV genes possess ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1023/B:VIRU.0000012262.89898.c7
更新日期:2004-01-01 00:00:00
abstract::Herpes simplex virus type 1 (HSV-1) reactivates from a small fraction of latently infected neurons in vivo and neuronally differentiated (ND), quiescently infected (QIF)-PC12 cells in vitro. This may be the result of reactivation initiating in only a few cells, or reactivation followed by premature termination of the ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-005-0052-6
更新日期:2006-10-01 00:00:00
abstract::Pneumonia virus of mice (PVM) is an enveloped RNA-containing virus of Family Paramyxoviridae. Sequences had been determined previously for a number of PVM genes, although these represented cloned cDNAs rather than consensus sequences. Sequences were not available for the 3' -leader and 5' -trailer regions that constit...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-004-5631-4
更新日期:2005-03-01 00:00:00
abstract::Duck hepatitis A virus type 1, (DHAV-1) 2A2pro, is one of the most highly conserved viral proteins within the DHAV serotypes. However, its effect on host cells is unclear. We predicted that DHAV-1 2A2pro was a GTPase-like protein based on the results of multiple sequence alignment and homologous modeling analysis. Upo...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-016-1364-4
更新日期:2016-12-01 00:00:00
abstract::The expression of geminivirus genes is controlled by bidirectional promoters which are located in the large intergenic region of the circular DNA genomes and specifically regulated by virus encoded proteins. In order to study the simultaneous regulation of both orientations of the DNA A and DNA B promoters of African ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1023/a:1008183827072
更新日期:2001-03-01 00:00:00
abstract::Two cucumber mosaic virus (CMV) isolates XJ1 and XJ2 were obtained from sugar beet showing yellow mosaic symptom in Shihezi, Xinjiang Uigur municipality of China. The coat protein gene of the two CMV isolates and their associated satellite RNAs were amplified by reverse transcriptase polymerase chain reaction (RT-PCR)...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-006-0068-6
更新日期:2006-12-01 00:00:00
abstract::A maximum clade credibility tree constructed using the full-length spike (S) and hemagglutinin-esterase genes revealed that Vietnamese Bovine coronavirus (BCoV) strains belong to a single cluster (C1); therefore, they might share a common origin with Cuban and Chinese BCoV strains. The omega values of cluster 1 (C1) a...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-019-01647-1
更新日期:2019-06-01 00:00:00
abstract::The exo-xis region of lambdoid phages contains open reading frames and genes that appear to be evolutionarily important. However, this region has received little attention up to now. In this study, we provided evidence that ea22, the largest gene of this region, favors the lysogenic pathway over the lytic pathway in c...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-020-01734-8
更新日期:2020-04-01 00:00:00
abstract::Viroids, the smallest and simplest agents of infectious disease, cause a number of economically important diseases of crop plants. Present evidence indicates that most of these diseases originated recently (in the 20th century) by chance transfer of viroids from endemically infected wild plants or by use of viroid-inf...
journal_title:Virus genes
pub_type: 杂志文章,评审
doi:10.1007/BF01728653
更新日期:1995-01-01 00:00:00
abstract::The emerging occurrence of antibiotic-resistant bacterial pathogens leads to a recollection of bacteriophage as antimicrobial therapeutics. This article presents a short overview of the clinical phage application including their use in military medicine and discusses the genotypic and phenotypic properties of a potent...
journal_title:Virus genes
pub_type: 杂志文章,评审
doi:10.1007/s11262-020-01735-7
更新日期:2020-04-01 00:00:00