Characterization and complete genome sequence analysis of Staphylococcus aureus bacteriophage SA12.

Abstract:

:Staphylococcus aureus is a well-known pathogen that causes several serious diseases in humans and animals. As part of the efforts to control this pathogen, a newly isolated bacteriophage, SA12, which specifically targets S. aureus, was characterized, and its genome was completely sequenced. Host range and bacteriophage challenge tests demonstrated its specific and efficient host lysis of S. aureus. The genome of phage SA12 consists of 42,902 bp length double-stranded DNA with 58 predicted ORFs-encoding phage structure, DNA manipulation, packaging, host lysis, and regulation proteins. The characterization and genome study of phage SA12 in this report is useful for understanding S. aureus-targeting bacteriophages and provides basic information for the further development of phage-based biocontrol agents against S. aureus.

journal_name

Virus Genes

journal_title

Virus genes

authors

Chang Y,Lee JH,Shin H,Heu S,Ryu S

doi

10.1007/s11262-013-0938-7

subject

Has Abstract

pub_date

2013-10-01 00:00:00

pages

389-93

issue

2

eissn

0920-8569

issn

1572-994X

journal_volume

47

pub_type

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