Abstract:
:Serum samples collected from 88 Peruvians with unexplained fever were analyzed for viral sequences using metagenomics. Nucleic acids of anelloviruses, pegivirus A (GBV-C), HIV, Dengue virus, and Oropouche virus were detected. We also characterized from two sera the RNA genomes of new species of partitivirus and dicistrovirus belonging to viral families known to infect fungi or arthropod, respectively. Genomic DNA of a putative fungal cellular host could be PCR amplified from the partitivirus-containing serum sample. The detection in human serum of nucleic acids from viral families not known to infect vertebrates may indicate contamination during sample collection and aliquoting or human infection by their presumed cellular host, here a fungus. The role, if any, of the non-vertebrate infecting viruses detected in serum in inducing fever is unknown.
journal_name
Virus Genesjournal_title
Virus genesauthors
Phan TG,Del Valle Mendoza J,Sadeghi M,Altan E,Deng X,Delwart Edoi
10.1007/s11262-017-1514-3subject
Has Abstractpub_date
2018-02-01 00:00:00pages
33-40issue
1eissn
0920-8569issn
1572-994Xpii
10.1007/s11262-017-1514-3journal_volume
54pub_type
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