Abstract：
PURPOSE:To assess the prevalence of spontaneous bacterial peritonitis (SBP) in asymptomatic patients with decompensated liver cirrhosis. MATERIAL AND METHODS:Patients (pts) with symptoms of decompensation of liver cirrhosis, ascites, and no signs indicating SBP were included to our study. Exclusion criteria include: 1/ clinical symptoms of infection, 2/ developing de novo or worsening hepatic encephalopathy, 3/ gastrointestinal bleeding within the last month, 4/ renal failure, 5/ antibiotic treatment or norfloxacin prophylaxis at admission. About 60 ml of ascitic fluid were drawn for lab examination. Pathologic assessment for atypical cells was also performed. RESULTS:37 patients fulfilled inclusion criteria. Their mean age was 56.2 ± 12.1. The Child-Pugh classification revealed 13 (35.1%) patients of class B and 24 (64.9%) patients of class C. The mean Model for End-Stage Liver Disease score in this group was 16.6 ± 6.8. The mean ascitic protein content was 1.85 ± 1.09 g/dL and mean neutrophil count 144.8 ± 445.1/mm3. Ascitic fluid analysis revealed: signs of bacterascites in 6 of 37 (16.2%) pts; neutrocytic ascites in 1 of 37 (2.7%) pts; and 2 of 37 (5.4%) pts met criteria for SBP. C-reactive protein level was the best predictor of infection [SBP(+) 47.9 ± 40.9 versus SBP(-) 11.7 ± 5.1; p= 0.0005]. CONCLUSIONS:The prevalence of SBP in asymptomatic cirrhotics with ascites is low. We observed the trend towards more frequent occurrence of the infection in patients suffered from severe liver disease (Child-Pugh C group).
journal_name
Adv Med Scijournal_title
Advances in medical sciencesauthors
Kasztelan-Szczerbinska B,Słomka M,Celinski K,Serwacki M,Szczerbinski M,Cichoz-Lach Hdoi
10.2478/v10039-011-0010-6subject
Has Abstractpub_date
2011-01-01 00:00:00pages
13-7issue
1eissn
1896-1126issn
1898-4002pii
S1896-1126(14)60056-0journal_volume
56pub_type
杂志文章abstract：BACKGROUND:Current risk stratification after acute myocardial infarction (MI) depends on left ventricular ejection fraction. Microvolt T-wave alternans (MTWA) is one of promising markers to predict cardiac events in patients after acute MI treated according to current guidelines. METHODS:In this single center study, 1...
journal_title：Advances in medical sciences
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更新日期：2012-01-01 00:00:00
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journal_title：Advances in medical sciences
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更新日期：2016-03-01 00:00:00
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更新日期：2007-01-01 00:00:00
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doi：
更新日期：2007-01-01 00:00:00
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pub_type： 杂志文章,随机对照试验
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更新日期：2013-01-01 00:00:00
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更新日期：2007-01-01 00:00:00
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更新日期：2020-09-01 00:00:00
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journal_title：Advances in medical sciences
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更新日期：2008-01-01 00:00:00
