Abstract:
:In this issue of Molecular Cell, Terrell et al. (2019) characterize the interactions of RAS-RAF complexes in live cells. Using bioluminescence resonance energy transfer (BRET) technology, they show that individual RAF family members exhibit distinct binding affinities to each RAS family protein, with CRAF exhibiting high binding affinities for all RAS proteins and BRAF exhibiting increased binding affinity for KRAS.
journal_name
Mol Celljournal_title
Molecular cellauthors
Venkatanarayan A,Malek Sdoi
10.1016/j.molcel.2019.11.020subject
Has Abstractpub_date
2019-12-19 00:00:00pages
853-855issue
6eissn
1097-2765issn
1097-4164pii
S1097-2765(19)30868-8journal_volume
76pub_type
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