SIRTing through breast cancer is just a survivin' game.

Abstract:

:Loss of endogenous tumor suppression is a critical step on the road to cancer. In a recent paper in Molecular Cell, Wang and colleagues provide evidence that inactivation of the pivotal BRCA1 tumor suppressor disrupts a safeguard gene network that opposes cell proliferation and cell survival.

journal_name

Mol Cell

journal_title

Molecular cell

authors

Luo J,Altieri DC

doi

10.1016/j.molcel.2008.10.007

subject

Has Abstract

pub_date

2008-10-24 00:00:00

pages

159-60

issue

2

eissn

1097-2765

issn

1097-4164

pii

S1097-2765(08)00689-8

journal_volume

32

pub_type

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