Conducting research with tribal communities: sovereignty, ethics, and data-sharing issues.

Abstract:

BACKGROUND:When conducting research with American Indian tribes, informed consent beyond conventional institutional review board (IRB) review is needed because of the potential for adverse consequences at a community or governmental level that are unrecognized by academic researchers. OBJECTIVES:In this article, we review sovereignty, research ethics, and data-sharing considerations when doing community-based participatory health-related or natural-resource-related research with American Indian nations and present a model material and data-sharing agreement that meets tribal and university requirements. DISCUSSION:Only tribal nations themselves can identify potential adverse outcomes, and they can do this only if they understand the assumptions and methods of the proposed research. Tribes must be truly equal partners in study design, data collection, interpretation, and publication. Advances in protection of intellectual property rights (IPR) are also applicable to IRB reviews, as are principles of sovereignty and indigenous rights, all of which affect data ownership and control. CONCLUSIONS:Academic researchers engaged in tribal projects should become familiar with all three areas: sovereignty, ethics and informed consent, and IPR. We recommend developing an agreement with tribal partners that reflects both health-related IRB and natural-resource-related IPR considerations.

authors

Harding A,Harper B,Stone D,O'Neill C,Berger P,Harris S,Donatuto J

doi

10.1289/ehp.1103904

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

6-10

issue

1

eissn

0091-6765

issn

1552-9924

journal_volume

120

pub_type

杂志文章
  • The human metallothionein gene family: structure and expression.

    abstract::Metallothioneins (MTs) are encoded by a multigene family in man. We have isolated those genes and analyzed the structure of some of them. The MT-II variant is encoded by a single functional gene: MT-IIA. The MT-IIB gene is a processed pseudogene derived from a reverse transcript of MT-II mRNA. On the other hand, the M...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.8454111

    authors: Karin M,Richards RI

    更新日期:1984-03-01 00:00:00

  • Comparative pathology of the nasal mucosa in laboratory animals exposed to inhaled irritants.

    abstract::The nasal cavity is susceptible to chemically induced injury as a result of exposure to inhaled irritants. Some responses of the nasal mucosa to inhaled toxicants are species specific. These species-related differences in response may be due to variations in structural, physiologic, and biochemical factors, such as gr...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.85-1568334

    authors: Harkema JR

    更新日期:1990-04-01 00:00:00

  • Lead and cadmium levels and balance and vestibular dysfunction among adult participants in the National Health and Nutrition Examination Survey (NHANES) 1999-2004.

    abstract:BACKGROUND:Few studies have been conducted to identify risk factors for balance and vestibular dysfunction in general populations, but previous studies have reported evidence of adverse effects of lead and cadmium on balance control in high-risk groups. OBJECTIVE:We evaluated the relationship between blood lead and ca...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.1103643

    authors: Min KB,Lee KJ,Park JB,Min JY

    更新日期:2012-03-01 00:00:00

  • Effects of polybrominated biphenyls (PBB) on immune response in rodents.

    abstract::Studies were performed to investigate the effects of FireMaster FF-1, a chemical fire retardant consisting of a mixture of polybrominated biphenyls (PBB), on immune functions in mice and rats. Animals received 22 daily treatments of 0.03, 0.3, 3.0, or 30 mg PBB/kg body weight in a period covering 30 days. PBB exposure...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.7823227

    authors: Luster MI,Faith RE,Moore JA

    更新日期:1978-04-01 00:00:00

  • The Case for Universal Screening of Private Well Water Quality in the U.S. and Testing Requirements to Achieve It: Evidence from Arsenic.

    abstract:BACKGROUND:The 1974 Safe Drinking Water Act (SDWA) regulates >170,000 public water systems to protect health, but not >13 million private wells. State and local government requirements for private well water testing are rare and inconsistent; the responsibility to ensure water safety remains with individual households....

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP629

    authors: Zheng Y,Flanagan SV

    更新日期:2017-08-03 00:00:00

  • Benzene adducts with rat nucleic acids and proteins: dose-response relationship after treatment in vivo.

    abstract::The dose-response relationship of the benzene covalent interaction with biological macromolecules from rat organs was studied. The administered dose range was 3.6 x 10(7) starting from the highest dosage employed, 486 mg/kg, which is oncogenic for rodents, and included low and very low dosages. The present study was i...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.8982259

    authors: Mazzullo M,Bartoli S,Bonora B,Colacci A,Grilli S,Lattanzi G,Niero A,Turina MP,Parodi S

    更新日期:1989-07-01 00:00:00

  • Long-term Fine Particulate Matter Exposure and Nonaccidental and Cause-specific Mortality in a Large National Cohort of Chinese Men.

    abstract:BACKGROUND:Cohort studies in North America and western Europe have reported increased risk of mortality associated with long-term exposure to fine particles (PM2.5), but to date, no such studies have been reported in China, where higher levels of exposure are experienced. OBJECTIVES:We estimated the association betwee...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP1673

    authors: Yin P,Brauer M,Cohen A,Burnett RT,Liu J,Liu Y,Liang R,Wang W,Qi J,Wang L,Zhou M

    更新日期:2017-11-07 00:00:00

  • Suppression of metallothionein-I/II expression and its probable molecular mechanisms.

    abstract::Metallothionein (MT) promoter was methylated in rat hepatoma and in mouse lymphosarcoma cells by methylation of cytosine within the CpG dinucleotide region. After demethylation of MT-I promoter in mouse lymphosarcoma cells or in the transplanted rat hepatoma with 5-azacytidine, a potent inhibitor of DNA methyltransfer...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.02110s5827

    authors: Jacob ST,Majumder S,Ghoshal K

    更新日期:2002-10-01 00:00:00

  • Interaction of alkylmercuric compounds with sodium selenite. I. Metabolism of ethylmercuric chloride administered alone and in combination with sodium selenite in rats.

    abstract::The effect of sodium selenite administered intragastrically in repeated doses to rats receiving ethylmercuric chloride po in various repeated doses (0.25 or 2.5 mg Hg/kg) on the excretion, whole-body retention, and organ distribution of mercury was studied. Selenium was found to affect the distribution of ethylmercury...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.39-1568742

    authors: Brzeźnicka EA,Chmielnicka J

    更新日期:1981-06-01 00:00:00

  • Colchicine antimitosis abolishes resiliency of postnatally developing rats to chlordecone-amplified carbon tetrachloride hepatotoxicity and lethality.

    abstract::We have previously reported that rats are resilient to the hepatotoxic and lethal combination of chlordecone (CD) and carbon tetrachloride (CCl4) during early postnatal development. The overall findings pointed to stimulated cell division and tissue repair mechanisms as the underlying cause of resistance. The objectiv...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.98106597

    authors: Dalu A,Rao PS,Mehendale HM

    更新日期:1998-09-01 00:00:00

  • Early-life exposure to outdoor air pollution and respiratory health, ear infections, and eczema in infants from the INMA study.

    abstract:BACKGROUND:Prenatal and early-life periods may be critical windows for harmful effects of air pollution on infant health. OBJECTIVES:We studied the association of air pollution exposure during pregnancy and the first year of life with respiratory illnesses, ear infections, and eczema during the first 12-18 months of a...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.1205281

    authors: Aguilera I,Pedersen M,Garcia-Esteban R,Ballester F,Basterrechea M,Esplugues A,Fernández-Somoano A,Lertxundi A,Tardón A,Sunyer J

    更新日期:2013-03-01 00:00:00

  • Climate and dengue transmission: evidence and implications.

    abstract:BACKGROUND:Climate influences dengue ecology by affecting vector dynamics, agent development, and mosquito/human interactions. Although these relationships are known, the impact climate change will have on transmission is unclear. Climate-driven statistical and process-based models are being used to refine our knowledg...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.1306556

    authors: Morin CW,Comrie AC,Ernst K

    更新日期:2013-11-01 00:00:00

  • Do the health benefits of cycling outweigh the risks?

    abstract:BACKGROUND:Although from a societal point of view a modal shift from car to bicycle may have beneficial health effects due to decreased air pollution emissions, decreased greenhouse gas emissions, and increased levels of physical activity, shifts in individual adverse health effects such as higher exposure to air pollu...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.0901747

    authors: Johan de Hartog J,Boogaard H,Nijland H,Hoek G

    更新日期:2010-08-01 00:00:00

  • Biological diversity, ecology, and global climate change.

    abstract::Worldwide climate change and loss of biodiversity are issues of global scope and importance that have recently become subjects of considerable public concern. Unlike classical public health issues and many environmental issues, their perceived threat lies in their potential to disrupt ecological functioning and stabil...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.9196167

    authors: Jutro PR

    更新日期:1991-12-01 00:00:00

  • Environmental practices for biomedical research facilities.

    abstract::As a result of the Leadership Conference on Biomedical Research and the Environment, the Facilities Committee focused its work on the development of best environmental practices at biomedical research facilities at the university and independent research facility level as well as consideration of potential involvement...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.00108s6945

    authors: Medlin EL,Grupenhoff JT

    更新日期:2000-12-01 00:00:00

  • Urinary biomarkers of prenatal atrazine exposure and adverse birth outcomes in the PELAGIE birth cohort.

    abstract:BACKGROUND:Despite evidence of atrazine toxicity in developing organisms from experimental studies, few studies--and fewer epidemiologic investigations--have examined the potential effects of prenatal exposure. OBJECTIVES:We assessed the association between adverse birth outcomes and urinary biomarkers of prenatal atr...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.1002775

    authors: Chevrier C,Limon G,Monfort C,Rouget F,Garlantézec R,Petit C,Durand G,Cordier S

    更新日期:2011-07-01 00:00:00

  • Disrupted patterns of behavior in natural populations as an index of ecotoxicity.

    abstract::This paper examines behavioral changes in natural populations of wildlife associated with pollution. Although some changes such as lack of nest attentiveness and decreased nest defense have been noted, the results have not been consistent and have been difficult to relate to specific pollutants. Experimental studies i...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.96104s2331

    authors: Peakall DB

    更新日期:1996-04-01 00:00:00

  • Caring for medically unexplained physical symptoms after toxic environmental exposures: effects of contested causation.

    abstract::Medically unexplained physical symptoms (MUPS) are persistent idiopathic symptoms that drive patients to seek medical care. MUPS syndromes include chronic fatigue syndrome, fibromyalgia syndrome, and multiple chemical sensitivities. When MUPS occur after an environmental exposure or injury, an adversarial social conte...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.02110s4641

    authors: Engel CC Jr,Adkins JA,Cowan DN

    更新日期:2002-08-01 00:00:00

  • Epidemiologic studies on possible health effects of intake of pyrolyzates of foods, with reference to mortality among Japanese Seventh-Day Adventists.

    abstract::To elucidate the effect of intake of mutagenic and/or carcinogenic pyrolysis products of proteins and amino acids on carcinogenesis in man, we have undertaken two epidemiologic cohort studies: one concerning the possible association of broiled fish consumption with cancer and the other concerning the cancer mortality ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.8667143

    authors: Kuratsune M,Ikeda M,Hayashi T

    更新日期:1986-08-01 00:00:00

  • Practical advancement of multipollutant scientific and risk assessment approaches for ambient air pollution.

    abstract:OBJECTIVES:The U.S. Environmental Protection Agency is working toward gaining a better understanding of the human health impacts of exposure to complex air pollutant mixtures and the key features that drive the toxicity of these mixtures, which can then be used for future scientific and risk assessments. DATA SOURCES:...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.1204939

    authors: Johns DO,Stanek LW,Walker K,Benromdhane S,Hubbell B,Ross M,Devlin RB,Costa DL,Greenbaum DS

    更新日期:2012-09-01 00:00:00

  • Testing their metal.

    abstract::Metals continually rank at the top of the U.S. Environmental Protection Agency's annual list of agents that pose the greatest hazard to the people of the United States. Metals aren't going away, either. They do not biodegrade, and they often concentrate in human and animal cells and tissue. Many metals are known human...

    journal_title:Environmental health perspectives

    pub_type: 新闻

    doi:10.1289/ehp.99107a244

    authors: Fisher BE

    更新日期:1999-05-01 00:00:00

  • Declining semen quality and increasing incidence of testicular cancer: is there a common cause?

    abstract::Male reproduction has been given little attention in science and in medical practice. However, a recent metaanalysis on semen quality, which clearly pointed to a decrease over the past 50 years, has been repeatedly quoted. Three recent reports have found that semen quality has declined among candidate semen donors dur...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.95103s7137

    authors: Carlsen E,Giwercman A,Keiding N,Skakkebaek NE

    更新日期:1995-10-01 00:00:00

  • Association of thyroid hormone concentrations with levels of organochlorine compounds in cord blood of neonates.

    abstract:BACKGROUND:Thyroid hormones are important regulators of brain development. During critical periods of development, even transient disorders in thyroid hormone availability may lead to profound neurologic impairment. Animal experiments have shown that certain environmental pollutants, including heavy metals and organoch...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.10486

    authors: Maervoet J,Vermeir G,Covaci A,Van Larebeke N,Koppen G,Schoeters G,Nelen V,Baeyens W,Schepens P,Viaene MK

    更新日期:2007-12-01 00:00:00

  • A Prospective Cohort Study of Adolescents' Memory Performance and Individual Brain Dose of Microwave Radiation from Wireless Communication.

    abstract:BACKGROUND:The potential impact of microwave radiofrequency electromagnetic fields (RF-EMF) emitted by wireless communication devices on neurocognitive functions of adolescents is controversial. In a previous analysis, we found changes in figural memory scores associated with a higher cumulative RF-EMF brain dose in ad...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP2427

    authors: Foerster M,Thielens A,Joseph W,Eeftens M,Röösli M

    更新日期:2018-07-23 00:00:00

  • Chemical plants remain vulnerable to terrorists: a call to action.

    abstract::U.S. chemical plants currently have potentially catastrophic vulnerabilities as terrorist targets. The possible consequences of these vulnerabilities echo from the tragedies of the Bhopal incident in 1984 to the terrorist attacks on 11 September 2001 and, most recently, Hurricanes Katrina and Rita. Findings from a 200...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.8762

    authors: Lippin TM,McQuiston TH,Bradley-Bull K,Burns-Johnson T,Cook L,Gill ML,Howard D,Seymour TA,Stephens D,Williams BK

    更新日期:2006-09-01 00:00:00

  • Identifying and Prioritizing Chemicals with Uncertain Burden of Exposure: Opportunities for Biomonitoring and Health-Related Research.

    abstract:BACKGROUND:The National Institutes of Health's Environmental influences on Child Health Outcomes (ECHO) initiative aims to understand the impact of environmental factors on childhood disease. Over 40,000 chemicals are approved for commercial use. The challenge is to prioritize chemicals for biomonitoring that may prese...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP5133

    authors: Pellizzari ED,Woodruff TJ,Boyles RR,Kannan K,Beamer PI,Buckley JP,Wang A,Zhu Y,Bennett DH,(Environmental influences on Child Health Outcomes).

    更新日期:2019-12-01 00:00:00

  • Blood lead level and risk of asthma.

    abstract::Asthma and lead poisoning are prevalent among urban children in the United States. Lead exposure may be associated with excessive production of immunoglobulin E, possibly increasing asthma risk and contributing to racial disparities. The objective of this study was to examine racial differences in the association of b...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.7453

    authors: Joseph CL,Havstad S,Ownby DR,Peterson EL,Maliarik M,McCabe MJ Jr,Barone C,Johnson CC

    更新日期:2005-07-01 00:00:00

  • U.S. cancer mortality 1950-1978: a strategy for analyzing spatial and temporal patterns.

    abstract::There are a number of technical and statistical problems in monitoring the temporal and spatial variation of local area death rates in the United States for evidence of systematically elevated risks. An analytic strategy is proposed to reduce one of the major statistical concerns, i.e., that of identifying areas with ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.8560369

    authors: Manton KG,Stallard E,Creason JP,Riggan WB

    更新日期:1985-05-01 00:00:00

  • Abstracts of the 26th Annual Conference of the International Society for Environmental Epidemiology (ISEE), 24-28 August 2014, Seattle, Washington.

    abstract::The 26th annual conference of the International Society for Environmental Epidemiology was held 24-28 August 2014 in Seattle, Washington. The conference theme was "From Local to Global: Advancing Science for Policy in Environmental Health." Sessions highlighted results assessing the burden of diseases from environment...

    journal_title:Environmental health perspectives

    pub_type:

    doi:10.1289/ehp.isee2014

    authors:

    更新日期:2014-10-30 00:00:00

  • Effects of endocrine disruptors on dehydroepiandrosterone sulfotransferase and enzymes involved in PAPS synthesis: genomic and nongenomic pathways.

    abstract:BACKGROUND:Sulfation plays an important role both in detoxification and in the control of steroid activity. Studies in rodents have shown that the conversion of dehydroepiandrosterone (DHEA) to DHEA-sulfate is involved in learning and the memory process. METHODS:The effects of a range of plasticizers and related compo...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.9365

    authors: Harris R,Turan N,Kirk C,Ramsden D,Waring R

    更新日期:2007-12-01 00:00:00