Abstract:
BACKGROUND:Climate influences dengue ecology by affecting vector dynamics, agent development, and mosquito/human interactions. Although these relationships are known, the impact climate change will have on transmission is unclear. Climate-driven statistical and process-based models are being used to refine our knowledge of these relationships and predict the effects of projected climate change on dengue fever occurrence, but results have been inconsistent. OBJECTIVE:We sought to identify major climatic influences on dengue virus ecology and to evaluate the ability of climate-based dengue models to describe associations between climate and dengue, simulate outbreaks, and project the impacts of climate change. METHODS:We reviewed the evidence for direct and indirect relationships between climate and dengue generated from laboratory studies, field studies, and statistical analyses of associations between vectors, dengue fever incidence, and climate conditions. We assessed the potential contribution of climate-driven, process-based dengue models and provide suggestions to improve their performance. RESULTS AND DISCUSSION:Relationships between climate variables and factors that influence dengue transmission are complex. A climate variable may increase dengue transmission potential through one aspect of the system while simultaneously decreasing transmission potential through another. This complexity may at least partly explain inconsistencies in statistical associations between dengue and climate. Process-based models can account for the complex dynamics but often omit important aspects of dengue ecology, notably virus development and host-species interactions. CONCLUSION:Synthesizing and applying current knowledge of climatic effects on all aspects of dengue virus ecology will help direct future research and enable better projections of climate change effects on dengue incidence.
journal_name
Environ Health Perspectjournal_title
Environmental health perspectivesauthors
Morin CW,Comrie AC,Ernst Kdoi
10.1289/ehp.1306556subject
Has Abstractpub_date
2013-11-01 00:00:00pages
1264-72issue
11-12eissn
0091-6765issn
1552-9924journal_volume
121pub_type
杂志文章,评审abstract::A microscopic, ultrastructural, and morphometric study was made of the gills of tench (Tinca tinca, L.) subjected to acute experimental lead nitrate poisoning. Twenty-one adult tench were subjected to poisoning and a further 22 were used as controls. Lesions were characterized by the appearance of edema and epithelial...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.9089137
更新日期:1990-11-01 00:00:00
abstract::The ability of a series of haloalkanes, haloethanols and haloacetaldehydes to induce mutations in Salmonella typhrimurium and preferentially to inhibit the growth of DNA polymerase-deficient E. coli (pol A(+)/pol A(-)) was investigated. For the haloalkanes investigated, the order of reactivities towards the E. coli po...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.772179
更新日期:1977-12-01 00:00:00
abstract::Pheromones are substances emitted by one individual of a species and eliciting a specific response in a second individual of the same species. In moths (Lepidoptera) generally females lure males for mating by emission of a sex attractant pheromone comprised of either one or more components. Since 1966 the identificati...
journal_title:Environmental health perspectives
pub_type: 历史文章,杂志文章,评审
doi:10.1289/ehp.14-1475097
更新日期:1976-04-01 00:00:00
abstract::The articles in this monograph focus on the mechanisms whereby ambient particulate matter (PM) and co-pollutants deposited in the respiratory tract cause cardiovascular and systemic effects, especially in persons with preexisting conditions such as allergic hyperresponsiveness and pulmonary, cardiac, and vascular dise...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.01109s4479
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND:Hydraulically fractured wells produce 2-14 million liters of wastewater, which may contain toxic and radioactive compounds. The wastewater is predominantly disposed of using Class II injection wells. OBJECTIVE:Our objective was to evaluate the relationship between sociodemographic characteristics and inject...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/EHP2663
更新日期:2018-06-27 00:00:00
abstract::The role of the physical environment as a determinant of health is a major concern reported by the general public as well as by many policymakers. However, it remains one of the health determinants for which few available measures or indicators are readily available. This lack of data is compounded by the fact that ev...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.01109s6817
更新日期:2001-12-01 00:00:00
abstract::A potential connection exists between exposure to organochlorine chemicals and the increasing prevalence of endometriosis. Evidence shows that dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin) can increase the incidence and severity of the disease in monkeys and can promote the growth or survival of endometrial tissue impl...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.0211015
更新日期:2002-01-01 00:00:00
abstract::The discovery of the potent mutagenicity of AF-2, which was once used in Japan as a food preservative, has exerted a great influence not only on screening procedures for carcinogenic compounds but also on legislative approaches to mutagenic substances. It promoted the synthesis of exceedingly sensitive and reliable te...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.7929183
更新日期:1979-04-01 00:00:00
abstract::Once a sign of modernization and growth, dams are often seen today as symbols of environmental and social devastation. Over 800,000 dams have been built worldwide to provide drinking water, flood control, hydropower, irrigation, navigation, and water storage. Dams do indeed provide these things,but at the cost of seve...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.971051050
更新日期:1997-10-01 00:00:00
abstract::The purpose of this study was to examine whether perinatal exposure to two major environmental endocrine-disrupting chemicals, bisphenol A (BPA; 0.1 mg/kg/day orally) and nonylphenol [NP; 0.1 mg/kg/day (low dose) and 10 mg/kg/day (high dose) orally] daily from gestational day 3 to postnatal day 20 (transplacental and ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.6961
更新日期:2004-08-01 00:00:00
abstract::Methylcobalamin (methyl-B12) has been implicated in the biomethylation of the heavy metals (mercury, tin, platinum, gold, and thallium) as well as the metalloids (arsenic, selenium, tellurium and sulfur). In addition, methylcobalamin has been shown to react with lead, but the lead-alkyl product is unstable in water. D...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.771943
更新日期:1977-08-01 00:00:00
abstract::Polychlorinated biphenyls (PCBs) and dioxins are known as neurotoxic compounds that may modulate sex steroid hormones. Steroid hormones play a mediating role in brain development and may influence behaviors that show sex differences, such as childhood play behavior. In this study we evaluated the effects of perinatal ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.021100593
更新日期:2002-10-01 00:00:00
abstract::The historical exposures to aromatic amines of various occupational groups are briefly reviewed. Modern studies indicate that other occupational groups might have risks worth investigating; these include machinists and workers in the chemical industry. Details of a recent investigation into the exposure of dye workers...
journal_title:Environmental health perspectives
pub_type: 历史文章,杂志文章
doi:10.1289/ehp.834913
更新日期:1983-03-01 00:00:00
abstract:BACKGROUND:Chronic exposure to well water arsenic (As) remains a major rural health challenge in Bangladesh and some other developing countries. Many mitigation programs have been implemented to reduce As exposure, although evaluation studies for these efforts are rare in the literature. OBJECTIVES:In this study we es...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.1409462
更新日期:2015-12-01 00:00:00
abstract::Gene expression is a unique way of characterizing how cells and organisms adapt to changes in the external environment. The measurements of gene expression levels upon exposure to a chemical can be used both to provide information about the mechanism of action of the toxicant and to form a sort of "genetic signature" ...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.8194
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Cadmium is a commonly occurring toxic food contaminant, but health consequences of early-life exposure are poorly understood. OBJECTIVES:We evaluated the associations between cadmium exposure and neurobehavioral development in preschool children. METHODS:In our population-based mother-child cohort study in...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.1104431
更新日期:2012-10-01 00:00:00
abstract::Population monitoring using methods of molecular epidemiology combined with reliable data on exposure is an extremely powerful approach to determine the effect of mutagens on human populations. Although human blood and urine have traditionally been used for biomonitoring, an increase in the use of placental and buccal...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.104-1469653
更新日期:1996-05-01 00:00:00
abstract::The steroids trenbolone acetate (TbA) and melengestrol acetate (MGA) are licensed as growth promoters for farm animals in several meat-exporting countries. Although many studies have explored their safety for both animals and consumers, little is known about their fate after excretion by the animal. Our study aimed to...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.011091145
更新日期:2001-11-01 00:00:00
abstract::Surface IR (infrared) modes of crystalline and fumed (amorphous) silica particles, calcined at temperatures up to 1095 degrees C, have been studied by Fourier transform infrared spectroscopy. The ability of these same particles to lyse cells has been measured by a hemolysis protocol. The untreated crystalline and amor...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.9086327
更新日期:1990-06-01 00:00:00
abstract::Research conducted in recent years has increased public health concern about the toxicity of lead at low dose and has supported a reappraisal of the levels of lead exposure that may be safely tolerated in the workplace. In this article, which appears as part of a mini-monograph on adult lead exposure, we summarize a b...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.9784
更新日期:2007-03-01 00:00:00
abstract::The activities of plants and plant/microbial associations may offer a viable means of accomplishing the in situ remediation of contaminated soils. Two uses of plants for phytoremediation are reported here. In one set of studies, the ability of plants to foster degradative microorganisms was investigated. Results indic...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.95103s413
更新日期:1995-06-01 00:00:00
abstract::[This corrects the article DOI: 10.1289/EHP2580.]. ...
journal_title:Environmental health perspectives
pub_type: 杂志文章,已发布勘误
doi:10.1289/EHP4002
更新日期:2018-07-05 00:00:00
abstract::During a 2-year chronic inhalation study on methylene chloride (2000 or 0 ppm; 6 hr/day, 5 days/week), gas-uptake pharmacokinetic studies and tissue partition coefficient determinations were conducted on female B6C3F1, mice after 1 day, 1 month, 1 year, and 2 years of exposure. Using physiologically based pharmacokine...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.96104858
更新日期:1996-08-01 00:00:00
abstract::Human fibroblasts (HFW) were 10-fold more susceptible than Chinese hamster ovary (CHO-K1) cells to sodium arsenite. Comparison of cellular antioxidant enzyme activities showed that CHO-K1 cells contained 3- and 8-fold more glutathione-peroxidase and catalase activities, respectively, than HFW cells. Since vitamin E, m...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.94102s3101
更新日期:1994-09-01 00:00:00
abstract::Relative potencies for 30 compounds scheduled for carcinogenic testing in the 2-year rodent bioassays were estimated based on comparisons with a wide variety of bioassay data for benzo[a]pyrene, nicotine, cisplatin, aflatoxin B1, and cyclophosphamide. Potential for oncogenic transformation of each of the compounds was...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.96104s51017
更新日期:1996-10-01 00:00:00
abstract:BACKGROUND:Because of complex interactions of climate variables at the levels of the pathogen, vector, and host, the potential influence of climate change on vector-borne and zoonotic diseases (VBZDs) is poorly understood and difficult to predict. Climate effects on the nonvector-borne zoonotic diseases are especially ...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.0901389
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:Prenatal and early-life periods may be critical windows for harmful effects of air pollution on infant health. OBJECTIVES:We studied the association of air pollution exposure during pregnancy and the first year of life with respiratory illnesses, ear infections, and eczema during the first 12-18 months of a...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.1205281
更新日期:2013-03-01 00:00:00
abstract::Serious problems emerge when evaluating evidence on lead neurotoxicity in children. The extent of these problems and ways to control them were explored in a study of 1291 children from the first class in the schools of Aarhus municipality, Denmark. The lead retention in circumpulpal dentin in shed deciduous teeth was ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.94-1567959
更新日期:1991-08-01 00:00:00
abstract:BACKGROUND:Global climate change is anticipated to reduce future cereal yields and threaten food security, thus potentially increasing the risk of undernutrition. The causation of undernutrition is complex, and there is a need to develop models that better quantify the potential impacts of climate change on population ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.1003311
更新日期:2011-12-01 00:00:00
abstract::In 1996 the U.S. Congress charged the U.S. Environmental Protection Agency to develop a screening program to test chemicals for their possible estrogenic and other endocrine effects. Shortly thereafter, the Chemical Guidelines Program of the Organisation for Economic Co-operation and Development's (OECD) Environmental...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.02110s3363
更新日期:2002-06-01 00:00:00