Abstract：
:The self-assembling protein shells of viruses have provided convenient scaffolds for the construction of many new materials with well-defined nanoscale architectures. In some cases, the native amino acid functional groups have served as nucleation sites for the deposition of metals and semiconductors, leading to organic-inorganic composites with interesting electronic, magnetic, optical, and catalytic properties. Other approaches have involved the covalent modification of the protein monomers, typically with the goal of generating targeting delivery vehicles for drug and imaging cargo. Covalently modified capsid proteins have also been used to generate periodic arrays of chromophores for use in light harvesting and photocatalytic applications. All of these research areas have taken advantage of the low polydispersity, high chemical stability, and intrinsically multivalent properties that are uniquely offered by these biological building blocks.
journal_name
Prog Mol Biol Transl Scijournal_title
Progress in molecular biology and translational scienceauthors
Dedeo MT,Finley DT,Francis MBdoi
10.1016/B978-0-12-415906-8.00002-9subject
Has Abstractpub_date
2011-01-01 00:00:00pages
353-92eissn
1877-1173issn
1878-0814pii
B978-0-12-415906-8.00002-9journal_volume
103pub_type
杂志文章,评审abstract：:Alzheimer's disease is a progressive neurodegenerative disease that is characterized histopathologically by the presence of plaques, mainly composed of Abeta amyloid and the tangles, mainly composed of hyperphosphorylated tau. To date, there is no treatment that can reverse the disease, and all the current therapeutic...
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abstract：:A substantive volume of research on autism spectrum disorder (ASD) has emerged in recent years adding to our understanding of the etiopathological process. Preclinical models in mice and rats have been highly instrumental in modeling and dissecting the contributions of a multitude of known genetic and environmental ri...
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journal_title：Progress in molecular biology and translational science
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journal_title：Progress in molecular biology and translational science
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journal_title：Progress in molecular biology and translational science
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journal_title：Progress in molecular biology and translational science
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journal_title：Progress in molecular biology and translational science
pub_type： 杂志文章,评审
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更新日期：2010-01-01 00:00:00
