Abstract：
BACKGROUND:The treatment of hypertension is an essential component of stroke prevention; however, the clinical management of patients with cerebrovascular disease is complicated by orthostatic hypotension (OH). The primary objectives were to: determine the prevalence of OH in a stroke outpatient clinic; describe categories of OH; and identify factors independently associated with the presence of OH. METHODS:Veterans with stroke, cared for in a multidisciplinary stroke clinic, were included. OH was defined as a ≥20 mmHg fall in systolic blood pressure (BP), a ≥10 mmHg fall in diastolic BP, or a ≥10 mmHg fall in systolic BP with symptoms. Multivariable logistic regression was used to identify factors associated with OH including demographics, comorbidites, stroke severity, and baseline BP. RESULTS:Among 60 patients with stroke, 16 (27%) patients had OH. Among those with OH, half were hypertensive, seven were normotensive, and one was hypotensive. A history of coronary artery disease was independently associated with the presence of OH. CONCLUSIONS:Orthostatic hypotension is present in about one quarter of outpatients with stroke, and coronary artery disease appears to be a risk factor. Stroke patients should be screened for OH given that the presence of positional BP changes may alter clinical management.
journal_name
J Neurol Scijournal_title
Journal of the neurological sciencesauthors
Phipps MS,Schmid AA,Kapoor JR,Peixoto AJ,Williams LS,Bravata DMdoi
10.1016/j.jns.2011.10.031subject
Has Abstractpub_date
2012-03-15 00:00:00pages
62-5issue
1-2eissn
0022-510Xissn
1878-5883pii
S0022-510X(11)00648-4journal_volume
314pub_type
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