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Basal ganglia germinoma: diagnostic value of MR spectroscopy and (11)C-methionine positron emission tomography.

Abstract：

:We herein report a 12-year-old girl with a basal ganglia germinoma who presented with right-sided hemiparesis after a minor head trauma. Magnetic resonance (MR) imaging revealed a minimally enhanced lesion involving the left putamen, thalamus, and corona radiata. The lesion showed low-signal intensity on T1-, and high intensity on T2- and diffusion-weighted imaging. The MR signal in the adjacent globus pallidum was also low on T2-weighted imaging. MR spectroscopy on the lesion showed a large lactate/lipid/macromolecule peak with a decreased NAA/Cr ratio, but no increase in the Cho/Cr ratio. However, posttraumatic infarction at the territory of lateral lenticulostriate artery was ruled out 1 month later. This was based on progression of the hemiparesis and neuroimaging results, including an increased Cho/Cr ratio and weak uptake on (11)C-methionine positron emission tomography of the basal ganglia lesion. Stereotaxic brain biopsy confirmed the diagnosis of germinoma.

journal_name

J Neurol Sci

journal_title

Journal of the neurological sciences

authors

Fujii Y,Saito Y,Ogawa T,Fujii S,Kamitani H,Kondo S,Horie Y,Togawa M,Senda M,Maegaki Y,Ohno K

doi

10.1016/j.jns.2008.02.006

subject

Has Abstract

pub_date

2008-07-15 00:00:00

pages

189-93

issue

1-2

eissn

0022-510X

issn

1878-5883

pii

S0022-510X(08)00083-X

journal_volume

270

pub_type

杂志文章

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