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Alteration of the maximal activity of the gluconeogenetic enzyme fructose-1,6-diphosphatase of skeletal muscle by cross-reinnervation. A histochemical and biochemical investigation of fatiguability-related aspects.

Abstract：

:Fatiguability is a determining characteristic of different muscle fibre types. An important aspect, indirectly related to fatiguability, gluconeogenesis, was investigated by observing fructose-1,6-diphosphatase (FDP) activity in experimental models prepared in rabbits by cross-reinnervation of the fatigue-resistant m.soleus (postural muscle) and the highly fatiguable m.flexor digitorum longus (fast muscle -- m.fdl). The resultant reprogramming of the m. soleus was associated with greatly intensified FDP activity. Changes in the m.fdl 6-9 months after cross-reinnervation indicated a shift in the opposite direction. The study adds some data on the much neglected state of fatiguability to the otherwise much explored field of alien reinnervation.

journal_name

J Neurol Sci

journal_title

Journal of the neurological sciences

authors

Jöbsis AC,Meijer AE,Vloedman AH

doi

10.1016/0022-510x(76)90250-1

subject

Has Abstract

pub_date

1976-11-01 00:00:00

pages

1-11

issue

1

eissn

0022-510X

issn

1878-5883

pii

0022-510X(76)90250-1

journal_volume

30

pub_type

杂志文章

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