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Analysis of neoplastic lesions in magnetic resonance imaging using self-organizing maps.

Abstract：

OBJECTIVE:To provide an improved method for the identification and analysis of brain tumors in MRI scans using a semi-automated computational approach, that has the potential to provide a more objective, precise and quantitatively rigorous analysis, compared to human visual analysis. BACKGROUND:Self-Organizing Maps (SOM) is an unsupervised, exploratory data analysis tool, which can automatically domain an image into selfsimilar regions or clusters, based on measures of similarity. It can be used to perform image-domain of brain tissue on MR images, without prior knowledge. DESIGN/METHODS:We used SOM to analyze T1, T2 and FLAIR acquisitions from two MRI machines in our service from 14 patients with brain tumors confirmed by biopsies--three lymphomas, six glioblastomas, one meningioma, one ganglioglioma, two oligoastrocytomas and one astrocytoma. The SOM software was used to analyze the data from the three image acquisitions from each patient and generated a self-organized map for each containing 25 clusters. RESULTS:Damaged tissue was separated from the normal tissue using the SOM technique. Furthermore, in some cases it allowed to separate different areas from within the tumor--like edema/peritumoral infiltration and necrosis. In lesions with less precise boundaries in FLAIR, the estimated damaged tissue area in the resulting map appears bigger. CONCLUSIONS:Our results showed that SOM has the potential to be a powerful MR imaging analysis technique for the assessment of brain tumors.

journal_name

J Neurol Sci

journal_title

Journal of the neurological sciences

authors

Mei PA,de Carvalho Carneiro C,Fraser SJ,Min LL,Reis F

doi

10.1016/j.jns.2015.10.032

subject

Has Abstract

pub_date

2015-12-15 00:00:00

pages

78-83

issue

1-2

eissn

0022-510X

issn

1878-5883

pii

S0022-510X(15)02524-1

journal_volume

359

pub_type

杂志文章

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