Multiple cerebral infarctions in a young patient with heroin-induced hypereosinophilic syndrome.

Abstract:

:Hypereosinophilic syndrome represents a rare cause for cerebral infarctions and inflammatory neurological disorders. Various possible pathogenic mechanisms for cerebral infarctions have already been discussed. Complex mechanisms including a local hypercoagulability by eosinophilic granules as well as a direct damage to endothelial cells, leading to alterations of the microcirculation seem to be involved. The changing pattern of heroin use to inhalation/sniffing leading to an increasing abuse may cause a rise in the prevalence of Heroin induced eosinophilia, as it has been reported in a case of eosinophilic pneumonia associated with heroin inhalation. To our knowledge, the present case report displays the first description of stroke in the setting of heroin induced hypereosinophilia. Thus, besides usual vasoconstriction, HES should be considered in drug-induced cerebral infarctions.

journal_name

J Neurol Sci

authors

Bolz J,Meves SH,Kara K,Reinacher-Schick A,Gold R,Krogias C

doi

10.1016/j.jns.2015.06.031

subject

Has Abstract

pub_date

2015-09-15 00:00:00

pages

193-5

issue

1-2

eissn

0022-510X

issn

1878-5883

pii

S0022-510X(15)00372-X

journal_volume

356

pub_type

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