Separation of cerebrospinal fluid specific proteins -- a methodological study. Part I.

abstract：:Controversy exists regarding the apolipoprotein E (ApoE) epsilon 4 allele association with vascular dementia (VaD). The results range from increased epsilon 4 frequency, similar to that found for Alzheimer's disease (AD), to no association at all. Our objective was to clarify the relationship between ApoE epsilon 4 al...

journal_title：Journal of the neurological sciences

authors： Traykov L,Rigaud AS,Baudic S,Smagghe A,Boller F,Forette F

更新日期：2002-11-15 00:00:00

abstract：PURPOSE:To investigate the presence of an ethnicity bias within patients presenting with optic neuritis in London. DESIGN:Observational cross-sectional study. METHODS:The ethnicity profile of all patients attending a neuro-ophthalmology clinic in central London with acute optic neuritis over a 16month period (n=86) w...

journal_title：Journal of the neurological sciences

authors： Storoni M,Pittock SJ,Weinshenker BG,Plant GT

更新日期：2012-01-15 00:00:00

abstract：BACKGROUND AND PURPOSE:Attention is one of the major cognitive domains adversely affected in multiple sclerosis (MS). The aim of the current study was to determine the effect of a single dose of methylphenidate on cognitive performance of MS patients with significant attention deficit. METHODS:In a double-blind placeb...

journal_title：Journal of the neurological sciences

authors： Harel Y,Appleboim N,Lavie M,Achiron A

更新日期：2009-01-15 00:00:00

abstract：:In a prospective study, we analysed the presence of monoclonal immunoglobulin (moIg) in the serum from 30 patients with amyotrophic lateral sclerosis (ALS) and 30 matched controls using a sensitive Western blot technique. The incidence of serum moIg was 60% in the ALS group and 13.3% in the control group. Most ALS ser...

journal_title：Journal of the neurological sciences

authors： Duarte F,Binet S,Lacomblez L,Bouche P,Preud'homme JL,Meininger V

更新日期：1991-07-01 00:00:00

abstract：:Adult-onset, chronic progressive spastic paraparesis may be due to a large number of causes and poses a diagnostic challenge. There are no recent evidence-based guidelines or comprehensive reviews to help guide diagnostic work-up. We survey the literature on chronic progressive spastic paraparesis, with special emphas...

journal_title：Journal of the neurological sciences

authors： Zhovtis Ryerson L,Herbert J,Howard J,Kister I

更新日期：2014-11-15 00:00:00

abstract：:Structural alterations of endoneurial microvessels occur in diabetic neuropathy and are statistically associated with severity of nerve fiber loss and teased fiber abnormality. It is therefore hypothesized that the microvessel alterations may cause or contribute to pathologic alterations of nerve fibers in diabetic ne...

journal_title：Journal of the neurological sciences

authors： Benstead TJ,Sangalang VE,Dyck PJ

更新日期：1990-10-01 00:00:00

abstract：:The product of the permeability x vascular surface rate area (PA) of the blood-brain barrier to [14C]sucrose has been measured in rats raised on synthetic diets in which the saturated/unsaturated fat constitution was controlled at high or low levels. Gas-liquid chromatography demonstrated marked differences in brain f...

journal_title：Journal of the neurological sciences

authors： Phillips SC,Cragg BG,Sinclair AJ

更新日期：1982-05-01 00:00:00

abstract：:The size and the distribution of type I and tye II fibres was determined in the gluteus maximus (21 cases), gluteus medius (56 cases) and tensor faciae latae (27 cases) muscles of patients with osteoarthritis of the hip. The patients were of both sexes, aged between 37 and 64 years (younger group) and between 65 and 7...

journal_title：Journal of the neurological sciences

authors： Sĭrca A,Susec-Michieli M

更新日期：1980-01-01 00:00:00

abstract：:The present study tested aspects of a novel etiological/pathogenetic hypothesis of Alzheimer's disease (AD), which proposes that alterations in endocrine regulation of peripheral calcium/phosphate (Ca/PO4) homeostasis (e.g., by glucocorticoids, vitamin D, etc.) induce and/or reflect altered calcium homeostasis and neu...

journal_title：Journal of the neurological sciences

authors： Landfield PW,Applegate MD,Schmitzer-Osborne SE,Naylor CE

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Clinical data across the globe especially in genetic diseases like Huntington's disease (HD) is most helpful when collected using standardized formats. This helps in proper comparison of clinical and genetic data. METHODS:Herein, we report clinical data on 26 genetically confirmed HD patients from 19 Indian...

journal_title：Journal of the neurological sciences

authors： Murgod UA,Saleem Q,Anand A,Brahmachari SK,Jain S,Muthane UB

更新日期：2001-09-15 00:00:00

abstract：BACKGROUND:Multiple sclerosis (MS) is a chronic inflammatory demyelinating disorder of the central nervous system. Evidences linking apolipoprotein E (APOE) to myelin repair, neuronal plasticity, and cerebral inflammatory processes suggest that it may be relevant in MS. The main goal of this study was to determine whet...

journal_title：Journal of the neurological sciences

authors： Rafiei M,Zarif Yeganeh M,Sheikholeslami S,Gozalpour E,Ghaffarpour M,Hedayati M

更新日期：2012-09-15 00:00:00

abstract：:This study evaluated the effect of low-level laser therapy (LLLT; 15 J/cm(2)) and a latex protein (F1) on a crush injury of the sciatic (ischiadicus) nerve. Seventy-two rats (male, 250 g) were divided into 6 groups: CG, control; EG, exposed nerve; IG, injured nerve without treatment; LG, injured nerve with LLLT; HG, i...

journal_title：Journal of the neurological sciences

authors： Dias FJ,Issa JP,Coutinho-Netto J,Fazan VP,Sousa LG,Iyomasa MM,Papa PC,Watanabe IS

更新日期：2015-02-15 00:00:00

abstract：:The recent history of clinical trials in ALS is marked by a great diversity in trial design. This has limited the comparability of the trial results, and has resulted in intense discussions about which parameters should or should not be evaluated when testing a new drug for ALS. This article discusses, without any cla...

journal_title：Journal of the neurological sciences

authors： Borasio GD

更新日期：1997-10-01 00:00:00

abstract：:Concentrations of somatostatin-like immunoreactivity (SLI) were examined in human cerebrospinal fluid (CSF). To validate the assay it was shown that CSF which had been run over a somatostatin immunoaffinity column showed no interference with binding of synthetic standards. Reversed phase HPLC showed that the immunorea...

journal_title：Journal of the neurological sciences

authors： Beal MF,Mazurek MF,Black PM,Martin JB

更新日期：1985-11-01 00:00:00

abstract：PURPOSE:Among different seizure types, tonic-clonic seizures are more significant because they are more often associated with morbidity. No prior study has been done to investigate risk factors associated with tonic-clonic seizures in patients with mesial temporal epilepsy. METHODS:In this retrospective study, all dru...

journal_title：Journal of the neurological sciences

authors： Asadi-Pooya AA,Rostami C,Rabiei AH,Sperling MR

更新日期：2015-12-15 00:00:00

abstract：:A point mutation at codon 210 (GTT to ATT) of the prion protein gene on chromosome 20 was found in a 48-year-old CJD-affected woman of a Chinese family. This affected woman had an early onset and long-duration form of CJD. Serial magnetic resonance image (MRI) analysis of this woman showed severe brain atrophy, promin...

journal_title：Journal of the neurological sciences

authors： Shyu WC,Hsu YD,Kao MC,Tsao WL

更新日期：1996-11-01 00:00:00

abstract：:We review post-infectious and post-vaccination neurological syndromes involving peripheral and central nervous system (CNS) and report an illustrative case of simultaneous occurrence of Guillain-Barré syndrome (GBS), confirmed by nerve conduction velocities, plus MRI-demonstrated transverse myelitis (TM) and acute enc...

journal_title：Journal of the neurological sciences

authors： Mancera-Páez O,Román GC,Pardo-Turriago R,Rodríguez Y,Anaya JM

更新日期：2018-12-15 00:00:00

abstract：BACKGROUND AND PURPOSE:Delirium frequently complicates acute stroke and worsens outcomes. Because delirium is potentially preventable, predicting its occurrence is essential. Although several prediction scores have been proposed, nurses need to quickly predict delirium in stroke care units (SCUs). We aimed to develop a...

journal_title：Journal of the neurological sciences

authors： Nakamizo T,Kanda T,Kudo Y,Sugawara E,Hashimoto E,Okazaki A,Usuda M,Nagai T,Hara H,Johkura K

更新日期：2020-08-15 00:00:00

abstract：:We report three related patients with autosomal dominant hereditary motor and sensory neuropathy (HMSN). An unusual and characteristic feature was calf enlargement, caused by muscle fiber hypertrophy predominantly of type 1 fibers. None of the family members showed atrophy of the legs. Sural nerve pathology disclosed ...

journal_title：Journal of the neurological sciences

authors： Sakashita Y,Sakato S,Komai K,Takamori M

更新日期：1992-11-01 00:00:00

abstract：:Sera from 40 patients with idiopathic Parkinson's disease and their age- and sex-matched controls were assayed for immunoglobulin G (IgG) antibodies against herpes simplex virus (HSV) type 1-induced cell surface antigens with the indirect immunofluorescent test. An increased level of HSV antibodies was found among the...

journal_title：Journal of the neurological sciences

authors： Marttila RJ,Rinne UK

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is unclear whether acute ischemic stroke exhibits a seasonal pattern in Japan. The aim of the present study was to elucidate seasonal differences in acute ischemic stroke. METHODS:Our study enrolled 12,660 patients with ischemic stroke (7943 men, 4717 women; mean age, 70.1 years, S.D. 11.5; m...

journal_title：Journal of the neurological sciences

authors： Ogata T,Kimura K,Minematsu K,Kazui S,Yamaguchi T,Japan Multicenter Stroke Investigators' Collaboration.

更新日期：2004-10-15 00:00:00

abstract：:To compare muscle fiber loss in young and old mdx mice, we have blocked regeneration in one leg with a high dose (18 Gy) of X-rays administered at two ages; 16 days, just prior to the onset of the myopathy, and 15 weeks, when the myopathy is considered to be quiescent. Mice were examined 4 days after irradiation to lo...

journal_title：Journal of the neurological sciences

authors： Pagel CN,Partridge TA

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVE:To assess the temporal and spatial variation in length of hospital stay for cerebrovascular disease in the United States over three decades. DESIGN:Age-, region-, and stroke type-specific length-of-hospital-stay data for nearly 4 million patients admitted with cerebrovascular disease were obtained for the Pr...

journal_title：Journal of the neurological sciences

authors： Lanska DJ

更新日期：1994-12-20 00:00:00

abstract：BACKGROUND:Direct oral anticoagulants (DOACs) can reduce the frequency of cardioembolic stroke with non-valvular atrial fibrillation as well as or better compared to vitamin K antagonists (VKAs). However, whether taking DOACs prior to stroke can prevent acute major cerebral artery occlusion (MCAO) has not been fully el...

journal_title：Journal of the neurological sciences

authors： Tomari S,Arima J,Yoshida T,Yamashita H,Sata R,Hamada R,Kanda N,Takashima H

更新日期：2019-07-15 00:00:00

abstract：:Genetic linkage studies were performed in 12 British families with von Hippel-Lindau disease (VHL) using RFLPs at three loci (DNF15S2, THRB, RAF1) on the short arm of chromosome 3. Linkage was detected between the VHL disease locus and RAF1 with a maximum lod score of 3.88 at a recombination fraction of 0.05 (confiden...

journal_title：Journal of the neurological sciences

authors： Maher ER,Bentley E,Yates JR,Barton D,Jennings A,Fellows IW,Ponder MA,Ponder BA,Benjamin C,Harris R

更新日期：1990-12-01 00:00:00

abstract：:Intergenerational stability of the CAG repeat number has been considered to be a specific molecular feature of SCA6 compared with other CAG repeat diseases. Nevertheless, we showed meiotic instability of the CAG repeats in the SCA6/CACNL1A gene in two Japanese SCA6 families, including de novo expansion. In one family,...

journal_title：Journal of the neurological sciences

authors： Shimazaki H,Takiyama Y,Sakoe K,Amaike M,Nagaki H,Namekawa M,Sasaki H,Nakano I,Nishizawa M

更新日期：2001-04-01 00:00:00

abstract：:Possible changes in brain metabolites in motor neurone disease/amytrophic lateral sclerosis (MND/ALS) were investigated using 1H magnetic resonance spectroscopy (MRS). A series of normal, healthy volunteer controls and MND patients have been studied using a spin echo (SE) 135 ms sequence, acquiring spectra from the re...

journal_title：Journal of the neurological sciences

authors： Jones AP,Gunawardena WJ,Coutinho CM,Gatt JA,Shaw IC,Mitchell JD

更新日期：1995-05-01 00:00:00

abstract：:Four unrelated patients are reported with muscle hypotonia, weakness, skeletal dysmorphism and respiratory insufficiency since childhood. Muscle tissues were found to contain a number of muscle fibres with abnormal structure. Peripherally located structures such as a cap lacking in ATP-ase and fast myosin activity, ri...

journal_title：Journal of the neurological sciences

authors： Fidziańska A

更新日期：2002-09-15 00:00:00

abstract：:Inherited muscular dystrophy of the chicken is an abnormality affecting the normal development and function of fast-twitch skeletal muscles. Several different strains of dystrophic chickens have been developed by selection for high lipid content in the pectoralis muscle and early onset of the disorder or by outcrossin...

journal_title：Journal of the neurological sciences

authors： Randall WR,Wilson BW

更新日期：1980-05-01 00:00:00

abstract：:Electron transport chain (ETC) dysfunction has been claimed to contribute to the expression of neurodegenerative disorders. We have investigated the effects of the treatment with rivastigmine, a commonly used cholinesterase inhibitor, on lymphocyte mitochondria of patients with Alzheimer's disease (AD). Increased enzy...

journal_title：Journal of the neurological sciences

authors： Casademont J,Miró O,Rodriguez-Santiago B,Viedma P,Blesa R,Cardellach F

更新日期：2003-01-15 00:00:00