Antihypertensive drugs and pancreatic cancer risk in patients with chronic pancreatitis: a Danish nationwide population-based cohort study.

abstract：:In a study of 157 patients with lymphoid malignancy, the phenotype of the tumour cells was correlated with the histological classification of the tumour using the Rappaport and the Kiel classifications. The markers used included E, Fc gamma, Fc micron (IgM) and C3d rosetting, estimation of SIg and CyIg, and tests for ...

journal_title：British journal of cancer

authors： Habeshaw JA,Catley PF,Stansfeld AG,Brearley RL

更新日期：1979-07-01 00:00:00

abstract：:There is increasing evidence that the presence of a systemic inflammatory response plays an important role in survival following curative resection for colorectal cancer. The present study evaluated the relationship between C-reactive protein concentrations and survival in a cohort of patients receiving adjuvant 5-flu...

journal_title：British journal of cancer

authors： Crozier JE,McKee RF,McArdle CS,Angerson WJ,Anderson JH,Horgan PG,McMillan DC

更新日期：2006-06-19 00:00:00

abstract：:Protein kinase B/Akt has been described as a central mediator of anti-apoptotic signals transduced by the PI3 kinase. Although the role of Akt in the suppression of apoptosis is well elucidated, a potential function of Akt in tumorigenesis and chemoresistance is less intensively documented. In this study, we describe ...

journal_title：British journal of cancer

authors： Schmidt M,Hövelmann S,Beckers TL

更新日期：2002-10-07 00:00:00

abstract：:A cell-free plasmid reactivation assay was used to determine the fidelity of DNA double-strand break (DSB) repair in a panel of eight DSB repair-proficient human tumour cell lines. Nuclear protein extracts derived from radiosensitive tumour cells were less capable of correctly rejoining EcoRI-induced DSBs than were si...

journal_title：British journal of cancer

authors： Britten RA,Liu D,Kuny S,Allalunis-Turner MJ

更新日期：1997-01-01 00:00:00

abstract：:Erbicin is a human anti-ErbB2 single-chain antibody fragment with high affinity and selectivity for ErbB2-positive cancer cells. Two anti-ErbB2 immunoconjugates, called Erb-hRNase and Erb-hcAb, have been prepared and found to be selectively cytotoxic on ErbB2-positive cancer cells in vitro and vivo. In Erb-hRNase, Erb...

journal_title：British journal of cancer

authors： De Lorenzo C,Troise F,Cafaro V,D'Alessio G

更新日期：2007-11-19 00:00:00

abstract：:The effect of an antiserum containing antibodies against cell surface components of PyBHK cells on the action of certain anticancer agents has been studied using a colony formation inhibition assay. The effects of x-rays, chlorambucil, CCNU and possibly ICRF 159 are augmented by the antiserum whereas methotrexate and ...

journal_title：British journal of cancer

authors： Rubens RD,Vaughan-Smith S,Dulbecco R

更新日期：1975-09-01 00:00:00

abstract：:Metabolic reprogramming towards aerobic glycolysis is a common feature of transformed cells and can be driven by a network of transcription factors. It is well established that c-Myc and hypoxia-inducible factor-1α (HIF-1α) contribute to metabolic reprogramming by driving the expression of glycolytic target genes. Mor...

journal_title：British journal of cancer

authors： Wilde BR,Ayer DE

更新日期：2015-12-01 00:00:00

abstract：:More women are living with and surviving breast cancer, because of improvements in breast cancer care. Trastuzumab (Herceptin) has significantly improved outcomes for women with HER2-positive tumours. Concerns about the cardiac effects of trastuzumab (which fundamentally differ from the permanent myocyte loss associat...

journal_title：British journal of cancer

authors： Jones AL,Barlow M,Barrett-Lee PJ,Canney PA,Gilmour IM,Robb SD,Plummer CJ,Wardley AM,Verrill MW

更新日期：2009-03-10 00:00:00

abstract：BACKGROUND:Epithelial-to-mesenchymal transition (EMT) enhances motility, stemness, chemoresistance and metastasis. Little is known about how various pathways coordinate to elicit EMT's different functional aspects in non-small cell lung cancer (NSCLC). Thymidylate synthase (TS) has been previously correlated with EMT t...

journal_title：British journal of cancer

authors： Siddiqui MA,Gollavilli PN,Ramesh V,Parma B,Schwab A,Vazakidou ME,Natesan R,Saatci O,Rapa I,Bironzo P,Schuhwerk H,Asangani IA,Sahin O,Volante M,Ceppi P

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:BRCAness is defined as shared tumour characteristics between sporadic and BRCA-mutated cancers. However, how to exactly measure BRCAness and its frequency in breast cancer is not known. Assays to establish BRCAness would be extremely valuable for the clinical management of these tumours. We assessed BRCAness...

journal_title：British journal of cancer

authors： Lips EH,Mulder L,Oonk A,van der Kolk LE,Hogervorst FB,Imholz AL,Wesseling J,Rodenhuis S,Nederlof PM

更新日期：2013-05-28 00:00:00

abstract：:To evaluate whether green tea consumption provides protection against stomach cancer, the relative risks (RRs) were calculated in the Japan Collaborative Study for Evaluation of Cancer Risk, sponsored by the Ministry of Health and Welfare (JACC Study). The study was based on 157 incident cases and 285 controls aged 40...

journal_title：British journal of cancer

authors： Hoshiyama Y,Kawaguchi T,Miura Y,Mizoue T,Tokui N,Yatsuya H,Sakata K,Kondo T,Kikuchi S,Toyoshima H,Hayakawa N,Tamakoshi A,Ohno Y,Yoshimura T,Japan Collaborative Cohort Study Group.

更新日期：2004-01-12 00:00:00

abstract：BACKGROUND:Cisplatin-radiotherapy is a preferred standard for locally advanced, head and neck squamous cell carcinoma (HNSCC). However, the cisplatin-attributable survival benefit is small and toxicity substantial. A biomarker of cisplatin resistance could guide treatment selection and spare morbidity. The ERCC1-XPF nu...

journal_title：British journal of cancer

authors： Bauman JE,Austin MC,Schmidt R,Kurland BF,Vaezi A,Hayes DN,Mendez E,Parvathaneni U,Chai X,Sampath S,Martins RG

更新日期：2013-10-15 00:00:00

abstract：:The extent to which plasma levels of angiogenic factors in healthy individuals and tumour volume-related variations in colorectal cancer affect the accuracy of circulating angiogenic factors as predictors of colorectal cancer vascularity is unknown. We used enzyme-linked immunosorbant assay to measure plasma vascular ...

journal_title：British journal of cancer

authors： Davies MM,Jonas SK,Kaur S,Allen-Mersh TG

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:The TP53 tumor suppressor gene is the most frequently altered gene in tumors and mutant p53 gain-of-function isoforms actively promote cancer malignancy. METHODS:A panel of wild-type and mutant p53 cancer cell lines of different tissues, including pancreas, breast, skin, and lung were used, as well as chron...

journal_title：British journal of cancer

authors： Cordani M,Butera G,Dando I,Torrens-Mas M,Butturini E,Pacchiana R,Oppici E,Cavallini C,Gasperini S,Tamassia N,Nadal-Serrano M,Coan M,Rossi D,Gaidano G,Caraglia M,Mariotto S,Spizzo R,Roca P,Oliver J,Scupoli MT,Donad

更新日期：2018-10-01 00:00:00

abstract：:Data collected from lung cancer patients attending the Victoria Clinic of the British Columbia Cancer Agency are used to investigate how resources are rationed in the treatment of non-small-cell lung cancer (NSCLC). An ordered logit model is estimated to analyse empirically the relationship between treatment selection...

journal_title：British journal of cancer

authors： Arndt K,Coy P,Schaafsma J

更新日期：1996-03-01 00:00:00

abstract：:Serum levels of pepsinogen and gastrin are parameters that can be used as biomarkers for gastric mucosa. The aim of this study was to validate these serum biomarkers, that is pepsinogen A (PGA), pepsinogen C (PGC), PGA/PGC ratio, and gastrin, as screening tests for precancerous lesions: atrophic chronic gastritis (ACG...

journal_title：British journal of cancer

authors： Broutet N,Plebani M,Sakarovitch C,Sipponen P,Mégraud F,Eurohepygast Study Group.

更新日期：2003-04-22 00:00:00

abstract：:The prognostic value of C-reactive protein, compared with ECOG performance status (ECOG-ps), in patients receiving alpha-interferon treatment for advanced renal cancer was assessed in 58 patients. In all, 55 patients died on follow-up. On multivariate analysis with ECOG-ps and C-reactive protein entered as covariates,...

journal_title：British journal of cancer

authors： Bromwich E,McMillan DC,Lamb GW,Vasey PA,Aitchison M

更新日期：2004-10-04 00:00:00

abstract：BACKGROUND:Patients with malignant pleural effusions (MPEs) generally have advanced disease with poor survival and few therapeutic options. Cells within MPEs may be used to stratify patients for targeted therapy. Targeted therapy with poly(ADP ribose) polymerase inhibitors (PARPi) depends on identifying homologous reco...

journal_title：British journal of cancer

authors： Patterson MJ,Sutton RE,Forrest I,Sharrock R,Lane M,Kaufmann A,O'Donnell R,Edmondson RJ,Wilson BT,Curtin NJ

更新日期：2014-07-08 00:00:00

abstract：:Chemoradiotherapy (CRT) is now widely accepted as the primary treatment modality for squamous cell cancer of the anus. While randomised trials have clearly shown CRT to be more effective than radiotherapy alone, there remains uncertainty over the optimal integration of chemotherapy and radiation. We describe a series ...

journal_title：British journal of cancer

authors： Melcher AA,Sebag-Montefiore D

更新日期：2003-05-06 00:00:00

abstract：:Secular, socioeconomic and urban-rural gradients and geographical differences in beef and fat consumption within the United States of America are compared with corresponding data on colorectal cancer incidence and mortality rates. These results, together with the results of most previous epidemiological studies, appea...

journal_title：British journal of cancer

authors： Enstrom JE

更新日期：1975-10-01 00:00:00

abstract：:The treatment of breast cancer patients has changed rapidly in the past decade, but empirical data at local and national level are scarce. Predicting the consequences of screening for primary treatment is consequently difficult. The aim of this analysis of records on admissions to hospital of women with breast cancer ...

journal_title：British journal of cancer

authors： de Koning HJ,van Dongen JA,van der Maas PJ

更新日期：1994-12-01 00:00:00

abstract：:The development of an altered stromal microenvironment is a common feature of many tumours including squamous cell carcinoma (SCC), and there is increasing evidence that these changes in the stroma, which include increased expression of proteases and cytokines, may actually promote tumour progression. A common finding...

journal_title：British journal of cancer

authors： Lewis MP,Lygoe KA,Nystrom ML,Anderson WP,Speight PM,Marshall JF,Thomas GJ

更新日期：2004-02-23 00:00:00

abstract：BACKGROUND:We evaluated systemic immune-inflammation index (SII) and its association with patient outcome in germ-cell tumours (GCTs). METHODS:Two independent cohorts of patients were analysed; the discovery set (n=171) from a single institution and the validation set (n=181) previously included in a study evaluating ...

journal_title：British journal of cancer

authors： Chovanec M,Cierna Z,Miskovska V,Machalekova K,Kalavska K,Rejlekova K,Svetlovska D,Macak D,Spanik S,Kajo K,Babal P,De Giorgi U,Mego M,Mardiak J

更新日期：2018-03-20 00:00:00

abstract：:Metastatic spread of some solid tumours is thought to depend upon the adhesion of tumour cells to the vascular endothelium followed by extravasation into surrounding tissues. We investigated the role of beta 1 integrins in the adhesion of the breast adenocarcinoma cell line MDA-MB-231 and the melanoma cell line RPMI-7...

journal_title：British journal of cancer

authors： Price EA,Coombe DR,Murray JC

更新日期：1996-12-01 00:00:00

abstract：:Apoptosis plays an important role in tumorigenesis. Tumour growth is determined by the rate of cell proliferation and cell death. We counted the number of apoptotic cells in haematoxylin and eosin (H&E)-stained tumour sections in series of 172 grade I and II invasive breast cancers with long-term follow-up. The number...

journal_title：British journal of cancer

authors： de Jong JS,van Diest PJ,Baak JP

更新日期：2000-01-01 00:00:00

abstract：:This corrects the article DOI: 10.1038/bjc.2017.85. ...

journal_title：British journal of cancer

authors： Ording AG,Veres K,Farkas DK,Adelborg K,Sørensen HT

更新日期：2018-03-20 00:00:00

abstract：:Tumour necrosis factor (TNF) related apoptosis-inducing ligand (TRAIL/APO2L) is a recently identified member of the TNF family, which induces programmed cell death in a variety of neoplastic cell types, but not in most nonneoplastic cells. In this study, we report on the identification of two novel alternative splice ...

journal_title：British journal of cancer

authors： Krieg A,Krieg T,Wenzel M,Schmitt M,Ramp U,Fang B,Gabbert HE,Gerharz CD,Mahotka C

更新日期：2003-03-24 00:00:00

abstract：:Preclinical models that can accurately predict outcomes in the clinic are much sought after in the field of cancer drug discovery and development. Existing models such as organoids and patient-derived xenografts have many advantages, but they suffer from the drawback of not contextually preserving human tumour archite...

journal_title：British journal of cancer

authors： Powley IR,Patel M,Miles G,Pringle H,Howells L,Thomas A,Kettleborough C,Bryans J,Hammonds T,MacFarlane M,Pritchard C

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF)-mediated angiogenesis mediates tumour growth and metastasis. Meningiomas are primarily benign, slow-growing, highly vascularised tumours. Aside from VEGF, there is little data on the function of major angiogenic proteins in meningiomas. METHODS:The VEGFA, platelet-d...

journal_title：British journal of cancer

authors： Pfister C,Pfrommer H,Tatagiba MS,Roser F

更新日期：2012-11-06 00:00:00

abstract：BACKGROUND:Cancer survival statistics are typically reported by using measures discounting the impact of other-cause mortality, such as net survival. This is a hypothetical measure and is interpreted as excluding the possibility of cancer patients dying from other causes. Crude probability of death partitions the all-c...

journal_title：British journal of cancer

authors： Wong KF,Lambert PC,Mozumder SI,Broggio J,Rutherford MJ

更新日期：2019-11-01 00:00:00