Abstract：
:A simple, eco-friendly, green routine co-precipitation method was experimented to synthesize iron nanoparticles (Fe-NPs) using the cell-free supernatant of actinobacteria. The biosynthesized nanoparticles were characterized by UV-Vis spectroscopy, X-ray diffractometer (XRD), energy-dispersive X-ray (EDX), scanning electron microscopy (SEM), atomic force microscopy (AFM), zeta potential analyser and Fourier transform infrared (FTIR) spectroscopy. The synthesized nanoparticles were crystalline, quasi-spherical in shape and their average size ranged from 65.0 to 86.7 nm. In our radical scavenging assays, the nanoparticles have revealed a strong antioxidant activity with respective standard ascorbic acid. The nanoparticles also exhibited a wide bactericidal action on pathogens namely Bacillus subtilis, Staphylococcus aureus, Klebsiella pneumoniae, Shigella flexneri and Escherichia coli. At 75 μg/ml concentration, the nanoparticles showed the highest inhibition against S. aureus (16.2 ± 0.45 mm), the lowest zone of inhibition was seen against K. pneumoniae (12.3 ± 0.50 mm) and moderate inhibition on other strains. Further, its cytotoxicity was seen as effective against DU145 and PC3 cells. The morphological changes caused in the prostate cell lines due to antiproliferative effect were observed through DAPI and AO/EB staining. This synthesis method specifies a new route for biosynthesis of Fe-NPs and the accomplished results illustrates that it can be used for a wide range of biomedical applications.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Rajeswaran S,Somasundaram Thirugnanasambandan S,Dewangan NK,Moorthy RK,Kandasamy S,Vilwanathan Rdoi
10.1007/s12011-019-01777-5subject
Has Abstractpub_date
2020-03-01 00:00:00pages
273-283issue
1eissn
0163-4984issn
1559-0720pii
10.1007/s12011-019-01777-5journal_volume
194pub_type
杂志文章abstract：:The developmental alterations in metallothionein (MT) proteins and zinc (Zn) were investigated in brains of two transgenic strains of mice. MT protein was measured by a cadmium binding assay and Zn by atomic absorption spectrophotometry. MT proteins were expressed at birth (day 1) both in MT-I overexpressing transgeni...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02784039
更新日期：1998-01-01 00:00:00
abstract：:The present study was aimed at estimating the current (2012) dietary intake of arsenic (As), cadmium (Cd), mercury (Hg), and lead (Pb) by the population of Catalonia, Spain. The temporal trends with respect to previous surveys, performed in 2000, 2005, and 2008, were also determined. For that purpose, metal concentrat...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-0138-x
更新日期：2014-12-01 00:00:00
abstract：:Calsyntenin-2 (Clstn2) and calsyntenin-3 (Clstn3) are the members of the cadherin superfamily and function to regulate the postsynaptic activity. Both proteins are known to play an important role in memory and learning. This study was designed to test the hypothesis that exposure of mothers to Pb in drinking water may...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02241-5
更新日期：2020-06-16 00:00:00
abstract：:The objective of this study was to investigate the iron source absorption in the small intestine of broiler. In situ ligated intestinal loops of 70 birds were poured into one of seven solutions, including inorganic iron (FeSO4, Fe2(SO4)3), organic Fe glycine chelate (Fe-Gly(II), Fe-Gly(III)), the mixtures (FeSO4 with ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-0179-1
更新日期：2015-02-01 00:00:00
abstract：:In this work, the interaction between nano-TiO(2) and trypsin was investigated, and the mechanisms of the interaction were explored by the methods of UV-vis detection, circular dichroism (CD), and fluorescence. The results clearly demonstrated that nano-TiO(2) had an inhibitory effect on the enzyme activity. The activ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8823-x
更新日期：2011-09-01 00:00:00
abstract：:The role of zinc (Zn) in hepatic steatosis of patients with HCV-related chronic liver disease (CLD-C) remains uncertain, although persistent HCV infection often evokes hepatic steatosis. The primary purpose of this study was to elucidate the contribution of Zn deficiency to hepatic steatosis in patients with CLD-C. Fi...
journal_title：Biological trace element research
pub_type： 临床试验,杂志文章
doi：10.1007/s12011-014-0177-3
更新日期：2015-02-01 00:00:00
abstract：:In this study, a solid-phase extraction method combined with atomic absorption spectrometry for extraction, preconcentration, and determination of iron (Fe(3+)), copper (Cu(2+)), and lead (Pb(2+)) ions at trace levels in water samples has been reported. The influences of effective parameters such as flow rate, pH, elu...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-011-9171-1
更新日期：2012-02-01 00:00:00
abstract：:In vivo X-ray fluorescence (XRF) techniques were used for biological monitoring of lead, cadmium, and mercury. Lead accumulates in bone, the level of which may thus be used for monitoring of exposure. However, there was no close association between lead levels in bone and exposure time, partly because of differences i...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02796636
更新日期：1987-08-01 00:00:00
abstract：:The effects of lanthanum on heat production of mitochondria isolated from Wistar rat liver were investigated with microcalorimetry; simultaneously, the effects on mitochondrial swelling and membrane potential (Δψ) were determined by spectroscopic methods. La(3+) showed only inhibitory action on mitochondrial energy tu...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-015-0269-8
更新日期：2015-09-01 00:00:00
abstract：:Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease of multifactorial origin. Studies have shown that trace elements such as zinc and copper may help maintain optimum function of the immune system and metabolism, while toxic metals such as lead may increase systemic autoimmunity. The curren...
journal_title：Biological trace element research
pub_type： 临床试验,杂志文章
doi：10.1007/s12011-018-1592-7
更新日期：2019-09-01 00:00:00
abstract：:Nano-titanium dioxide is a kind of widely used nanomaterial that exhibits various adverse outcomes. However, the role of oxidative stress in this regard remains controversial. This study aimed to evaluate whether oxidative stress is one of the toxicity mechanisms induced by nano-titanium dioxide in rats and mice model...
journal_title：Biological trace element research
pub_type： 杂志文章,meta分析
doi：10.1007/s12011-019-01761-z
更新日期：2020-03-01 00:00:00
abstract：:The liver of Hooded Seal (Cystophora cristata) consists of six lobes of unequal sizes. Extensive sampling by means of cutout samples covering the depth horizon 2-30 mm below liver surface indicates that the liver may be considered homogeneous as to concentrations of zinc, cadmium, mercury, and selenium (residuals of o...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02789141
更新日期：1990-01-01 00:00:00
abstract：:A rapid cyclic instrumental neutron activation analysis (CINAA) method has been used to determine the selenium content of 27 duplicate diet samples from each of the 27 districts surrounding Pinhel, Portugal. The accuracy and precision of the CINAA method have been evaluated by analyzing certified reference materials a...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02992719
更新日期：1990-07-01 00:00:00
abstract：:The origins of the usage of different substances in beauty, skin, body, hair, and nails care products can be found in ancient times. To achieve better quality and enhance their effects, some additives such as preservatives, stabilizers, mineral pigments, dye, and shine were added to these products. Some of these subst...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-015-0477-2
更新日期：2016-04-01 00:00:00
abstract：:Although coenzyme Q10 (CoQ10) is a component of the oxidative phosphorylation process in mitochondria that converts the energy in carbohydrates and fatty acids into ATP to drive cellular machinery and synthesis, its effect in type I diabetes is not clear. We have studied the effect of 4 wk of treatment with CoQ10 (10 ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:109:1:025
更新日期：2006-01-01 00:00:00
abstract：:The effects of zinc on growing rats were characterized using the dietary zinc-deficient (ZD) and Zinc-overdose (ZO) models. Zinc deficiency had negative effects on the host final body weight and liver zinc content, whereas zinc overdose had positive effects. In order to identify the molecular changes in the liver resp...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02686028
更新日期：2007-02-01 00:00:00
abstract：:Manganese (Mn) is an essential nutrient for both host and pathogen. Recent studies have demonstrated the nutritional immunity of Mn against Salmonella infection in mammals. To investigate the effect of high dietary Mn on immune responses of broilers following Salmonella challenge, 144 1-day-old male broilers were fed ...
journal_title：Biological trace element research
pub_type： 临床试验,杂志文章
doi：10.1007/s12011-017-1060-9
更新日期：2018-02-01 00:00:00
abstract：:The concentrations of 7 metals (lead, cadmium, manganese, copper, nickel, silver, and chromium) were determined in 32 different species of wild mushrooms. The mushroom samples, which have been using for food and some medical purposes, were collected from Konya, an Inner Anatolian region of Turkey. The highest metal co...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:110:1:79
更新日期：2006-04-01 00:00:00
abstract：:Sediments from 14 stations in the Foshan Waterway, a river crossing the industrial district of Guangdong Province, South China, were sampled and subsequently analyzed. The 14 stations were selected for the pollution discharging features of the river, such as the hydrology, the distribution of pollution sources, and th...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-013-9789-2
更新日期：2013-11-01 00:00:00
abstract：:Zinc is a nutritionally essential trace element required for many biological functions to be successfully carried out. The aim of the present work was to study the influence of zinc on the intestinal absorption of L-threonine and on the aminopeptidase N activity in rabbit jejunum, after in vitro addition and/or oral a...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02784557
更新日期：1996-07-01 00:00:00
abstract：:Recent studies have identified a new existence of a genetically programmed and regulated cell death characterized by necrotic cell death morphology, termed necroptosis. Lead (Pb) is a ubiquitously distributed environmental pollutant that is highly toxic to animals and human beings. However, no detailed report has been...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02094-y
更新日期：2020-12-01 00:00:00
abstract：:The effects of selenium were investigated on three human colon cancer cell lines: Caco 2, HRT 18, and HT 29. At low concentrations (10-100 nM), selenium stimulated cell growth in serum-free medium. Thus, selenium is an essential trace element for cell proliferation. At higher concentrations, selenium inhibited cell gr...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02919096
更新日期：1989-04-01 00:00:00
abstract：:Oxidative stress is a main factor in the pathogenesis of severe acute pancreatitis (SAP). The ability of zinc (Zn) to retard oxidative processes has been recognized for many years. This study aims to examine the levels of free oxygen radicals and antioxidant enzyme in SAP rats and know the effect of Zn supplementation...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-9971-1
更新日期：2014-06-01 00:00:00
abstract：:Studies were performed on adult and fetal rats receiving either a zinc-deficient (<0.5 ppm) diet and/or ethanol (20%) throughout pregnancy. Liver zinc levels were depressed in fetuses exposed toin utero zinc deficiency, but brain zinc levels were unchanged. Ethanol had no effect on the concentration of zinc in the sev...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02795685
更新日期：1987-12-01 00:00:00
abstract：:The effects of nutritional copper deficiency on carrageenin edema in the rat were investigated with emphasis on studying the correlation between the degree of copper deficiency and the degree of edema. Carrageenin paw edema in both copper-sufficient and copper-deficient groups of rats was compared after either 20, 40,...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02917181
更新日期：1989-01-01 00:00:00
abstract：:This study assessed the effect of dietary selenium (Se) deficiency on male reproductive function in chicken. A total of 180 Hy-line laying cocks (1 day old; Weiwei) were randomly divided into 2 groups (n = 90) of Se-deficient chickens and control chickens. The control group was fed a basic diet (containing 0.15 mg of ...
journal_title：Biological trace element research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s12011-015-0534-x
更新日期：2016-06-01 00:00:00
abstract：:Various studies indicate the role of manganese (Mn) in the virulence of pathogens. Salmonella is an intracellular pathogen which is able to multiply within the macrophages. The present study was therefore, designed to assess the effect of Mn supplementation on Salmonella-macrophage interactions particularly in referen...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-009-8406-x
更新日期：2010-01-01 00:00:00
abstract：:Zinc deficiency, which is common among Iranian populations, is believed to play a crucial role in the onset and progression of mood disorders such as depression in different stages of life. We have therefore investigated the relationship between serum/dietary zinc status and depression scores among adolescent girls li...
journal_title：Biological trace element research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s12011-018-1301-6
更新日期：2018-11-01 00:00:00
abstract：:The concentrations of various trace elements in amniotic fluid (AF) change over the course of pregnancy, with gestational age and fetus growth. The aim of the present study was to evaluate the concentrations of selected essential and toxic elements in AF and their relations to maternal and fetal parameters. The study ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-015-0557-3
更新日期：2016-07-01 00:00:00
abstract：:Copper (Cu) parenteral administration is used in a beef cow-calf operations to prevent or correct Cu deficiency in bovines. At present, Zinc (Zn) salts have been incorporated to complement Cu antioxidant effect. A risk of hepatotoxicity generated by overdose is a negative consequence of injectable Cu application. Cu-Z...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-017-0965-7
更新日期：2017-10-01 00:00:00
