Plant defense compounds: systems approaches to metabolic analysis.

Abstract:

:Systems biology attempts to answer biological questions by integrating across diverse genomic data sets. With the increasing ability to conduct genomics experiments, this integrative approach is being rapidly applied across numerous biological research communities. One of these research communities investigates how plants utilize secondary metabolites or defense metabolites to defend against attack by pathogens and other biotic organisms. This use of systems biology to integrate across transcriptomics, metabolomics, and genomics is significantly enhancing the rate of discovery of genes, metabolites, and bioactivities for plant defense compounds as well as extending our knowledge of how these compounds are regulated. Plant defense compounds are also providing a unique proving platform to develop new approaches that enhance the ability to conduct systems biology with existing and previously unforseen genomics data sets. This review attempts to illustrate both how systems biology is helping the study of plant defense compounds and vice versa.

journal_name

Annu Rev Phytopathol

authors

Kliebenstein DJ

doi

10.1146/annurev-phyto-081211-172950

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

155-73

eissn

0066-4286

issn

1545-2107

journal_volume

50

pub_type

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