Retroperitoneal primary mucinous adenocarcinoma: A case report.

abstract：:Hepatic epithelioid angiomyolipoma (EAML) is a rare type of hepatic tumor. Due to a lack of adequate understanding about this tumor, hepatic EAML is often misdiagnosed as other diseases with similar clinical characteristics such as hepatic cancer. In the present study, 3 cases of hepatic EAML are reported, and the mai...

journal_title：Oncology letters

authors： Liu W,Meng Z,Liu H,Li W,Wu Q,Zhang X,E C

更新日期：2016-06-01 00:00:00

abstract：:Despite advancements in treatment regimens, the mortality rate of patients with oral tongue squamous cell carcinoma (OTSCC) is high. In addition, the signaling pathways and oncoproteins involved in OTSCC progression remain largely unknown. Therefore, the aim of the present study was to identify specific prognostic mar...

journal_title：Oncology letters

authors： Zhong P,Liu L,Shen A,Chen Z,Hu X,Cai Y,Lin J,Wang B,Li J,Chen Y,Peng J

更新日期：2019-12-01 00:00:00

abstract：:The aim of this study was to examine the effects of compound Radix Sophorae Flavescentis on the proliferation of esophageal carcinoma TE-8 cells and to elucidate the mechanisms involved. For this purpose, we incubated TE-8 cells in medium containing various concentrations (0, 0.0125, 0.025, 0.05, 0.1, 0.2, 0.4 and 0.8...

journal_title：Oncology letters

authors： Yang X,Cai W,Yang Q,Lu Z,Li J,Yu J

更新日期：2015-10-01 00:00:00

abstract：:Abnormal regulation of long non-coding RNAs (lncRNAs) appears to be a primary feature of numerous types of human cancer. However, the association between the dysregulation of lncRNAs and functional alterations in gastric cancer (GC) remains unclear. In previous studies, we applied microarray and bioinformatics analyse...

journal_title：Oncology letters

authors： Li CY,Liang GY,Yao WZ,Sui J,Shen X,Zhang YQ,Ma SM,Ye YC,Zhang ZY,Zhang WH,Yin LH,Pu YP

更新日期：2018-06-01 00:00:00

abstract：:Local adjuvant treatment of giant cell tumours (GCTs) of the bone with phenol has led to a significant reduction in recurrence rates. In the current study, the optimal phenol concentration and duration of intralesional exposure were evaluated. Specimens of GCTs were exposed to various concentrations of phenol solution...

journal_title：Oncology letters

authors： Mittag F,Leichtle C,Kieckbusch I,Wolburg H,Rudert M,Kluba T,Leichtle U

更新日期：2013-05-01 00:00:00

abstract：:Hyperparathyroidism is characterized by the oversecretion of parathyroid hormone biochemically and increased cell proliferation histologically. Primary and secondary hyperparathyroidism exhibit distinct pathophysiology but share certain common microscopic features. The present study performed the first genome-wide exp...

journal_title：Oncology letters

authors： Lee F,Lee JJ,Jan WC,Wu CJ,Chen HH,Cheng SP

更新日期：2016-07-01 00:00:00

abstract：:Preoperative radiotherapy improves local disease control and disease-free survival in patients with advanced rectal cancer; however, a reliable predictive biomarker for the effectiveness of irradiation has yet to be elucidated. Phosphorylation of H2A histone family member X (H2AX) to γ-H2AX is induced by DNA double-st...

journal_title：Oncology letters

authors： Kawashima S,Kawaguchi N,Taniguchi K,Tashiro K,Komura K,Tanaka T,Inomata Y,Imai Y,Tanaka R,Yamamoto M,Inoue Y,Lee SW,Kawai M,Tanaka K,Okuda J,Uchiyama K

更新日期：2020-09-01 00:00:00

abstract：:Ulcerative colitis (UC) is thought to be associated with precancerous lesions that can ultimately lead to colon cancer. Therefore, diagnostic markers for colorectal dysplasia and cancer are urgently needed for patients with UC. Stathmin 1 (STMN1) is a novel cancer biomarker that is also a novel target for treatment in...

journal_title：Oncology letters

authors： Osone K,Yokobori T,Katayama C,Takahashi R,Kato R,Tatsuski H,Takada T,Yajima R,Motegi Y,Ogawa H,Fujii T,Ojima H,Nakamura J,Yao T,Shirabe K,Kuwano H

更新日期：2019-11-01 00:00:00

abstract：:Hepatitis B virus × protein (HBx) serves an important role in the pathogenesis of the hepatitis B virus infection. Previous studies have reported that the interaction between HBx and hepatocyte mitochondria is an important factor leading to liver cell injury and apoptosis, ultimately inducing the formation of liver ca...

journal_title：Oncology letters

authors： Ling LR,Zheng DH,Zhang ZY,Xie WH,Huang YH,Chen ZX,Wang XZ,Li D

更新日期：2020-04-01 00:00:00

abstract：:The expression of macrophage inhibitory cytokine-1 (MIC-1) of early gastric cancer treated using endoscopic mucosal resection (EMR) and its correlation with prognosis were investigated. One hundred and forty-seven patients with early gastric cancer (less than 20 mm in diameter) were recruited and assigned into an obse...

journal_title：Oncology letters

authors： Zhang N,Lu B

更新日期：2017-08-01 00:00:00

abstract：:Chylothorax is the accumulation of lymph fluid in the pleura. Gastric carcinoma with chylothorax and lymphedema as the initial manifestations has rarely been reported, with only 14 cases reported to date. The mechanisms of gastric carcinoma generating chylothorax have not yet been determined. The current study reports...

journal_title：Oncology letters

authors： Wu J,Lv L,Zhou K,Huo J

更新日期：2016-04-01 00:00:00

abstract：:The response of triple-negative breast cancer (TNBC) to chemotherapy is heterogeneous; particular subtype classifications based on mRNA gene expression analysis have been demonstrated to be associated with a pathological complete response (pCR). The aim of the present study was to investigate additional clinical and p...

journal_title：Oncology letters

authors： Nakashoji A,Matsui A,Nagayama A,Iwata Y,Sasahara M,Murata Y

更新日期：2017-10-01 00:00:00

abstract：:A significant factor that affects the value of the Ki-67 proliferation index (IK) is the interpretation and implementation approach. This method is based on visual or automated methods to count tumor nuclei labeled with Ki-67 antigen, and is prone to errors. Detection of Ki-67 is a useful tool in breast cancer and con...

journal_title：Oncology letters

authors： Suciu C,Muresan A,Cornea R,Suciu O,Dema A,Raica M

更新日期：2014-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the fourth most common cause of cancer-associated death worldwide. Glioma-associated oncogene homolog 1 (Gli1) is a key component and functions as a reliable marker of Hedgehog signaling pathway activation. Previous studies have demonstrated that Gli1 serves important roles in the pro...

journal_title：Oncology letters

authors： Hu Z,Xie F,Hu A,Xu M,Liu Y,Zhang J,Xiao J,Song Y,Zhong J,Chen B

更新日期：2020-11-01 00:00:00

abstract：:In the present study, Frizzled-2 (Fz2), a receptor of the Wnt ligand, was investigated as a potential target of molecular therapy for hepatocellular carcinoma (HCC). Quantitative polymerase chain reaction (PCR) was performed to determine the expression levels of Fz2. A surgical specimen of HCC was immunostained with a...

journal_title：Oncology letters

authors： Tomizawa M,Shinozaki F,Motoyoshi Y,Sugiyama T,Yamamoto S,Sueishi M

更新日期：2014-10-01 00:00:00

abstract：:Carbonyl reductase 1 (CBR1) is theorized to participate in various cellular processes, such as signal transduction, apoptosis, carcinogenesis and drug resistance, and is highly expressed in certain malignancies, including lung tumors. Several studies have provided evidence that gene polymorphisms may affect susceptibi...

journal_title：Oncology letters

authors： Guo Y,Shen Y,Xia Y,Gu J

更新日期：2017-11-01 00:00:00

abstract：:Lung cancer is the most common cause of cancer-related mortality in men and women. Non-small cell lung cancer (NSCLC) represents close to 90% of all lung cancers. When diagnosed, >50% of patients are >65 years old. Through an improved understanding of the molecular mechanisms involved in lung oncogenesis, molecular-ta...

journal_title：Oncology letters

authors： Antonelli G,Libra M,Panebianco V,Russo AE,Vitale FV,Colina P,D'Angelo A,Rossello R,Ferraù F

更新日期：2016-01-01 00:00:00

abstract：:Polydatin, extracted from Polygonum cuspidatum, is known for its anti-platelet aggregation and anti-inflammatory effects. However, studies on the association of polydatin with cancer are limited, particularly with regards to epithelial-mesenchymal transition (EMT)-associated migration and invasion of cancer cells. The...

journal_title：Oncology letters

authors： Jiang J,Chen Y,Dong T,Yue M,Zhang Y,An T,Zhang J,Liu P,Yang X

更新日期：2019-05-01 00:00:00

abstract：:Colorectal cancer (CRC) is the third leading cause of cancer-associated mortalities. Long non-coding RNAs (lncRNAs) have been identified as key regulators in the occurrence and development of CRC. The lncRNA urothelial cancer associated 1 (UCA1) has been demonstrated to promote the development of numerous different ty...

journal_title：Oncology letters

authors： Zhang L,Zheng C,Sun Z,Wang H,Wang F

更新日期：2019-10-01 00:00:00

abstract：:Human lactoferrin (hLF) is a multifunctional glycoprotein that inhibits cancer growth. However, the inhibitory effect of this glycoprotein in cervical cancer remains inconclusive. This study investigated the efficacy of hLF on the inhibition of U14 cervical cancer in vivo. Recombinant adenovirus carrying hLF (Ad-hLF) ...

journal_title：Oncology letters

authors： Shi H,Li W

更新日期：2014-03-01 00:00:00

abstract：:Dopamine receptor 2 (DR2) may be a biomarker for various types of cancer. Ovarian cancer cells overexpress DR2; therefore, blocking DR2 may be a novel treatment strategy for ovarian cancer. Thioridazine, a DR2 blocker, has antineoplastic activity in a variety of cancer cells. In view of the requirement for novel thera...

journal_title：Oncology letters

authors： Yong M,Yu T,Tian S,Liu S,Xu J,Hu J,Hu L

更新日期：2017-12-01 00:00:00

abstract：:Lung cancer, a malignant tumor, is the most frequently fatal cancer, with poor survival rates in the advanced stages. In order to improve the understanding of this disease, and to improve the outcomes of patients, additional studies are required. In the present study, differentially expressed genes (DEGs) in patients ...

journal_title：Oncology letters

authors： Xu X,Cao L,Zhang Y,Yin Y,Hu X,Cui Y

更新日期：2018-01-01 00:00:00

abstract：:Berberine is sourced from multiple medicinal herb resources and is easy to extract. With the advantages of low price, safety and convenience, berberine may have potential for wide clinical use. The present study aimed to investigate whether berberine inhibited the viability of colon cancer and whether it regulated the...

journal_title：Oncology letters

authors： Lü Y,Han B,Yu H,Cui Z,Li Z,Wang J

更新日期：2018-04-01 00:00:00

abstract：:The present study aimed to investigate the association between insulin-like growth factor-1 (IGF-1) and matrix metalloproteinase-11 (MMP-11) expression in gastric cancer (GC) and the underlying mechanisms in SGC-7901 cells. Reverse transcription-quantitative polymerase chain reaction analysis revealed that the express...

journal_title：Oncology letters

authors： Su C,Wang W,Wang C

更新日期：2018-05-01 00:00:00

abstract：:The purpose of the present study was to evaluate the newest status of patients diagnosed Burkitt lymphoma (BL), an aggressive lymphoma subset with a high cure rate. Furthermore, the study aimed to create prognostic nomograms to consider various prognostic factors and estimate patient survival, paving the way for clini...

journal_title：Oncology letters

authors： Lu J,Tan H,Li B,Chen S,Xu L,Zou Y

更新日期：2020-01-01 00:00:00

abstract：:As a rare hypopharyngeal diverticulum, Killian-Jamieson diverticulum (KJD) is usually incidentally detected, small, asymptomatic and likely to be misdiagnosed as a thyroid nodule. In order to avoid unnecessary treatments resulting from misdiagnosis, principles to distinguish between esophageal diverticula and thyroid ...

journal_title：Oncology letters

authors： Cao L,Ge J,Zhao D,Lei S

更新日期：2016-10-01 00:00:00

abstract：:Bone metastasis is an uncommon event in advanced gastric cancer patients and bone metastases are rarely detected as isolated lesions. However, eleven years after treatment for locally advanced gastric cancer, including total gastrectomy followed by adjuvant chemotherapy, a 49-year-old female was admitted to the IX Div...

journal_title：Oncology letters

authors： Iovino F,Orditura M,Auriemma PP,Ciorra FR,Giordano G,Orabona C,Bara F,Sergio R,Savastano B,Fabozzi A,Laterza MM,Ventriglia J,Petrillo A,Della Corte CM,DE Vita F

更新日期：2015-03-01 00:00:00

abstract：:The long non-coding RNA (lncRNA) plasmacytoma variant translocation 1 (PVT1) has been identified as an oncogene in numerous diseases, and aberrant lncRNA PVT1 expression has been associated with the development of cancer. However, the underlying mechanism by which lncRNA PVT1 affects cell invasion in esophageal cancer...

journal_title：Oncology letters

authors： Zheng X,Hu H,Li S

更新日期：2016-10-01 00:00:00

abstract：:Breast cancer is the second leading cause of cancer-associated mortality in females in the USA. Hsa-miR-599 was demonstrated to function as a tumour suppressor during cancer progression. However, the function and mechanism of the hsa-miR-599 in human breast cancer remain elusive. Thus, the aim of the present study was...

journal_title：Oncology letters

authors： Wang Y,Sui Y,Zhu Q,Sui X

更新日期：2017-09-01 00:00:00

abstract：:Retroperitoneal tumors are lesions with diverse pathological subtypes that originate from the retroperitoneal space; ~40% of these tumors are benign. Due to such lesions often surrounding and associating with vital abdominal blood vessels, a complete surgical resection is difficult. The current study presents a novel ...

journal_title：Oncology letters

authors： Wan Z,Yin T,Chen H,Li D

更新日期：2016-05-01 00:00:00