Chylothorax and lymphedema as the initial manifestations of gastric carcinoma: A case report and review of the literature.

abstract：:There is increasing evidence that microRNAs (miRNAs) play important roles in tumor progression and development by targeting different genes, including gastric cancer (GC). However, the role of miR-16 in GC is so far unclear. Herein, we examined the function and potential mechanism of miR-16 in GC. Reverse transcriptio...

journal_title：Oncology letters

authors： Jiang X,Wang Z

更新日期：2018-09-01 00:00:00

abstract：:Individuals >65 years old account for a large proportion of cancer patients, and usually have poor prognoses due to relative weaker physiological function and lower drug tolerance. To characterize the efficacy and safety of dendritic cell (DC)-activated cytokine-induced killer cell (CIK)-mediated treatment, and develo...

journal_title：Oncology letters

authors： Liu Y,Liu H,Liu H,He P,Li J,Liu X,Chen L,Wang M,Xi J,Wang H,Zhang H,Zhu Y,Zhu W,Ning J,Guo C,Sun C,Zhang M

更新日期：2016-12-01 00:00:00

abstract：:Activating transcription factor 2 (ATF2) is a member of the cAMP response element binding protein family that heterodimerizes and activates other transcription factors involved in stress and DNA damage responses, growth, differentiation and apoptosis. ATF2 has been investigated as a potential carcinogenic biomarker in...

journal_title：Oncology letters

authors： You Z,Zhou Y,Guo Y,Chen W,Chen S,Wang X

更新日期：2016-01-01 00:00:00

abstract：:Malignant mesothelioma in the mediastinum is rare and the majority of known cases have been reported as 'localized mesothelioma'. The present study reports a case of an upper mediastinal tumor, which was diagnosed through thoracoscopic surgery and surgical biopsies of the mass. A computed tomography scan revealed a gi...

journal_title：Oncology letters

authors： Zhang S,Song P,Zhang B

更新日期：2013-07-01 00:00:00

abstract：:The aim of the present study was to determine the efficacy of microsurgery treatment for parasagittal meningioma in the central gyrus region. A microsurgical technique was used to treat 26 patients with large parasagittal meningioma in the central gyrus region. The Rolandic and draining veins and the peritumoral norma...

journal_title：Oncology letters

authors： Bi N,Xu RX,Liu RY,Wu CM,Wang J,Chen WD,Liu J,Xu YS,Wei ZQ,Li T,Zhang J,Bai JY,Dong B,Fan SJ,Xu YH

更新日期：2013-09-01 00:00:00

abstract：:Metastasis remains a notable issue in patients with newly diagnosed colorectal carcinomas (CRC). Although anti-angiogenic therapies target metastatic diseases, hypoxia-inducible factor-1 α (HIF-1α) and vascular endothelial growth factor (VEGF) status are routinely evaluated in primary tumors as metastatic sites are in...

journal_title：Oncology letters

authors： Yin L,Li J,Ma D,Li D,Sun Y

更新日期：2020-05-01 00:00:00

abstract：:A growing body of evidence suggests that oncogenesis is associated with systemic inflammation. The present study investigated white blood cell and platelet indices, whose values change during the inflammatory response, in women with invasive ductal breast carcinoma. Preoperatively obtained white blood cell and platele...

journal_title：Oncology letters

authors： Mantas D,Kostakis ID,Machairas N,Markopoulos C

更新日期：2016-08-01 00:00:00

abstract：:The aim of the present study was to investigate the change in the total protein content between the serum and saliva of female patients with breast cancer and in healthy females. The study was conducted between October 2012 and November 2013. There were 80 females in the present study with 40 breast cancer patients an...

journal_title：Oncology letters

authors： Al-Muhtaseb SI

更新日期：2014-12-01 00:00:00

abstract：:Being biomarkers that reflect host nutritional and immune status, prognostic nutritional index (PNI) and neutrophil/lymphocyte ratio (NLR) have been identified to be independent prognostic factors in various malignancies. The aim of the present study was to determine the predictive value of these parameters for the pr...

journal_title：Oncology letters

authors： Yang T,Mao P,Chen X,Niu X,Xu G,Bai X,Xie W

更新日期：2019-02-01 00:00:00

abstract：:The IL-6R/JAK2/STAT3 pathway mediated by interleukin-6 (IL-6) plays an important role in the occurrence and development of multiple myeloma (MM), which is associated with decreased microRNA-451a. However, the biological function of microRNA-451a in MM remains unclear. The bone marrow (BM) of patients with MM was sampl...

journal_title：Oncology letters

authors： Zhong L,Xu Z,Jin X,He Y,Zhang J,Jiang T,Chen J

更新日期：2020-12-01 00:00:00

abstract：:The present study aimed to evaluate regional liver function impairment following transcatheter arterial chemoembolization (TACE), assessed by magnetic resonance imaging (MRI) enhanced by gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA). Additionally, this study evaluated the associations betwe...

journal_title：Oncology letters

authors： Xiao YD,Paudel R,Liu H,Zhang B,Ma C,Zhou SK

更新日期：2015-03-01 00:00:00

abstract：:Change in mitochondrial DNA (mtDNA) copy number has been reported in esophageal squamous cell carcinoma (ESCC). However, its prognostic implication in ESCC remains largely unknown. Using reverse transcription-quantitative PCR assay, the mtDNA copy number was assessed in a cohort of patients with ESCC (n=141) and norma...

journal_title：Oncology letters

authors： Li H,Tian Z,Zhang Y,Yang Q,Shi B,Hou P,Ji M

更新日期：2018-01-01 00:00:00

abstract：:The evaluation of minimal residual disease (MRD) in acute leukemia (AL) is currently recognized as a potential critical tool to assess the response and relapse rate of treatments. The present study investigated serum peptides from patients with AL to identify biomarkers that would be useful in providing clinical evalu...

journal_title：Oncology letters

authors： Song W,Wang N,Li W,Wang G,Hu J,He K,Li Y,Meng Y,Chen N,Wang S,Hu L,Xu B,Wang J,Li A,Cui J

更新日期：2013-11-01 00:00:00

abstract：:Pulmonary large-cell neuroendocrine carcinoma (LCNEC) is a rare and malignant form of lung cancer with a poor prognosis for patients. The common sites of metastases are the liver, adrenal glands, bone and brain. LCNEC rarely metastasizes to the small intestine, ovaries, tonsils, mandible, vulva or spine. To the best o...

journal_title：Oncology letters

authors： Yang G,Pan Z,Ma N,Qu L,Yuan T,Pang X,Yang X,Dong L,Liu S

更新日期：2017-10-01 00:00:00

abstract：:The aim of the present study was to investigate the effects of the heat shock protein (HSP)90 inhibitor AUY922 on the proliferation and migratory ability of renal cell carcinoma (RCC) cells. The expression of HSP90 was measured in vitro using western blotting and quantitative polymerase chain reaction in the ACHN and ...

journal_title：Oncology letters

authors： Zhu J,Zhu Y,Qi W,Qiu W

更新日期：2015-08-01 00:00:00

abstract：:The present study compared two methods for the detection of severe cervical dysplasia in women with atypical squamous cells of underdetermined significance (ASC-US) cytology; digital colposcopy with adjunctive dynamic spectral imaging (DSI) and conventional colposcopy. IMPROVE-COLPO was a two-arm cross-sectional study...

journal_title：Oncology letters

authors： Harris KE,Lavin PT,Akin MD,Papagiannakis E,Denardis S

更新日期：2020-10-01 00:00:00

abstract：:Increasing evidence has suggested that microRNAs (miRNAs; miRs) are extensively involved in the progression of chondrosarcoma (CHS). However, few studies have investigated the functional role of miR-525 in CHS tissues and cells. In the present study, it was discovered that miR-525 levels were decreased in CHS tissues ...

journal_title：Oncology letters

authors： Liu B,Song X,Yan Z,Yang H,Shi Y,Wu J

更新日期：2019-01-01 00:00:00

abstract：:The present study investigated the effects of N-methyl-D-aspartate receptor (NMDAR) antagonist ketamine, on the growth of gliomas. To analyze the effects of ketamine treatment, rat C6 glioma cells arising from astrocytes, and RNB cells representing non-malignant astrocytes, were examined. In ketamine-treated C6 cells,...

journal_title：Oncology letters

authors： Niwa H,Furukawa KI,Seya K,Hirota K

更新日期：2017-10-01 00:00:00

abstract：:The association between endometriosis and malignant transformation has often been described in the medical literature. A search was conducted between 1966 and 2010 through the English language literature (online Medline PubMed database) using the keywords endometriosis combined with malignant transformation. The searc...

journal_title：Oncology letters

authors： Higashiura Y,Kajihara H,Shigetomi H,Kobayashi H

更新日期：2012-07-01 00:00:00

abstract：:The liver kinase B1 (LKB1)/5'-adenosine monophosphate-activated protein kinase pathway has been reported to facilitate glioma cell growth by improving growth conditions. To investigate the clinical significance of LKB1 in human gliomas western blot analysis and quantitative polymerase chain reaction experiments were p...

journal_title：Oncology letters

authors： Huang J,Chen H,Wei Q,Zhang Z,Zhong Z,Xu Y

更新日期：2017-03-01 00:00:00

abstract：:Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein and exhibits an organ-dependent expression pattern in cancer. PSCA is upregulated in prostate cancer and downregulated in gastric cancer. PSCA is expressed in a variety of human organs. Although certain studies prev...

journal_title：Oncology letters

authors： Ono H,Sakamoto H,Yoshida T,Saeki N

更新日期：2018-03-01 00:00:00

abstract：:In previous studies, we observed that STAT1 and Survivin correlated negatively with gastric cancer tissues, and that the functions of the IFN-γ-STAT1 pathway and Survivin in gastric cancer are the same as those reported for other types of cancer. In this study, the SGC7901 gastric cancer cell line and 83 gastric cance...

journal_title：Oncology letters

authors： Deng H,Zhen H,Fu Z,Huang X,Zhou H,Liu L

更新日期：2012-01-01 00:00:00

abstract：:The incidence of gastric cancer is high, especially in China. The present study aims to provide a novel therapeutic target for gastric cancer. Peripheral blood, cancerous and paracancerous tissues were collected from patients with gastric cancer. T-cell immunoglobulin mucin domain-3 (Tim-3) expression in T-cells was m...

journal_title：Oncology letters

authors： Yu J,Zhang H,Sun S,Sun S,Li L

更新日期：2019-02-01 00:00:00

abstract：:N-myc downstream-regulated gene 1 (NDRG1) is a multifunctional protein associated with carcinogenesis and tumor progression. The function of NDRG1 in hepatocellular carcinoma (HCC) cells remains controversial. The present study investigated the role of NDRG1 in HCC as well as its molecular mechanism using a range of t...

journal_title：Oncology letters

authors： Song Y,Wu G,Zhang M,Kong Q,Du J,Zheng Y,Yue L,Cao L

更新日期：2017-05-01 00:00:00

abstract：:Circular RNAs (circRNAs) are a novel type of endogenous non-coding RNA that have gained attention from researchers for their involvement in multiple biological processes. circRNAs are ubiquitously expressed in eukaryotic cells and regulate gene expression at the transcriptional or post-transcriptional level by interac...

journal_title：Oncology letters

authors： Ren X,Du Y,You L,Zhao Y

更新日期：2017-12-01 00:00:00

abstract：:The clinical efficiency of bone transport distraction osteogenesis in the reconstruction of large tibial defects following resection of osteosarcoma remains unclear. The current study presents two cases of large tibial defects treated with bone transport distraction using an Orthofix external fixator. Case 1 was a 29-...

journal_title：Oncology letters

authors： Yang Z,Jin L,Tao H,Yang D

更新日期：2016-08-01 00:00:00

abstract：:Low-grade cribriform cystadenocarcinoma (LGCCC) is a malignant salivary gland tumor. LGCCC occurs rarely, with the parotid gland being the most commonly afflicted site. Few cases arise in other sites. The present study reports a case of LGCCC that occurred at the palatal gland of the hard palate. A 56-year-old female ...

journal_title：Oncology letters

authors： Kokabu S,Nojima J,Kayano H,Yoda T

更新日期：2015-10-01 00:00:00

abstract：:TERT is the main functional unit of telomerase, which maintains telomere length and chromosome structure stability. TERT has been shown to act as a key factor in various biological processes, such as cell proliferation, via uncharacterized mechanisms. We transfected HEp-2 laryngeal carcinoma cells with a TERT overexpr...

journal_title：Oncology letters

authors： Jiang Y,Chen C,Chen SM,Wang YQ,Xu Y,Wang Y,Chen Z,Xiao BK,Tao ZZ

更新日期：2013-07-01 00:00:00

abstract：:The aim of the present study was to investigate the inhibitory effects of dihydroartemisinin (DHA) on the primary tumor growth and metastasis of the human breast cancer cell line, MDA-MB-231, in vitro. The expression levels of urokinase-type plasminogen activator (uPA) were detected by immunocytochemistry in two cell ...

journal_title：Oncology letters

authors： Zhang S,Ma Y,Jiang J,Dai Z,Gao X,Yin X,Xi W,Min W

更新日期：2014-05-01 00:00:00

abstract：:Partial hydatidiform mole and coexisting fetus (PHMCF) is a rare condition that presents a dilemma for physicians and the parents of the fetus, particularly when PHMCF is detected during the second trimester of pregnancy. The present study reports a case of PHMCF terminated by induction of labor via administration of ...

journal_title：Oncology letters

authors： Wang Y,Qian H,Wang J

更新日期：2015-12-01 00:00:00