Medical termination of a partial hydatidiform mole and coexisting fetus during the second trimester: A case report.

Abstract:

:Partial hydatidiform mole and coexisting fetus (PHMCF) is a rare condition that presents a dilemma for physicians and the parents of the fetus, particularly when PHMCF is detected during the second trimester of pregnancy. The present study reports a case of PHMCF terminated by induction of labor via administration of Rivanol at 17 weeks. Follow-up measurements of serum β-human chorionic gonadotropin (β-HCG) levels, as well as imaging studies, indicated the presence of persistent trophoblastic disease (PTD) and lung metastases. The patient was therefore admitted for three courses of chemotherapy. Subsequently, the metastases receded and β-HCG levels decreased to within the normal range. The patient demonstrated no disease recurrence for 1 year. Following a review of the relevant literature, to the best of our knowledge, all PHMCF cases terminated by medical induction of labor during the second trimester resulted in the development of PTD and lung metastases. However, three cases of PHMCF that were terminated by caesarean section during the third trimester did not develop PTD or metastases. The present study therefore hypothesized that medical termination may not be a safe therapeutic strategy for the treatment of PHMCF during the second trimester, and that pregnancy should be allowed to continue empirically.

journal_name

Oncol Lett

journal_title

Oncology letters

authors

Wang Y,Qian H,Wang J

doi

10.3892/ol.2015.3743

subject

Has Abstract

pub_date

2015-12-01 00:00:00

pages

3625-3628

issue

6

eissn

1792-1074

issn

1792-1082

pii

OL-0-0-3743

journal_volume

10

pub_type

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