Expression and clinical significance of extracellular matrix metalloproteinase inducer, EMMPRIN/CD147, in human osteosarcoma.

abstract：:The present study reports the case of a 20-year-old female who was identified to have a left renal angiomyolipoma (AML) with hemorrhage. Following temporary conservative observation, the patient received continuous ultrasonic follow-up. Due to the rapid growth of the lesion, further examinations were performed. Comput...

journal_title：Oncology letters

authors： Liang W,Xu S

更新日期：2015-11-01 00:00:00

abstract：:The present study aimed to identify polypeptides that specifically bond to breast cancer stem cells from a phage display random 12 peptide library, in addition to the affinity and specificity of polypeptides. A phage display random 12 peptide library was screened using breast cancer stem cells as targets isolated from...

journal_title：Oncology letters

authors： Liu F,Qi CL,Kong M,Liu TT,Li L,Li BJ

更新日期：2016-12-01 00:00:00

abstract：:Resveratrol has been reported to inhibit or induce DNA damage, depending upon the type of cell and the experimental conditions. Dietary resveratrol is present in the body predominantly as metabolites and limited data is available concerning the activities of these metabolic products. In the present study, physiologica...

journal_title：Oncology letters

authors： Zunino SJ,Storms DH

更新日期：2017-08-01 00:00:00

abstract：:Breast metastasis is a rare pattern of distant metastasis from nasopharyngeal carcinoma (NPC) following curative treatment. The present study reported two patients with breast metastasis from NPC and reviewed four such patients reported in the literature, including the analysis of clinical profiles, pathological diagn...

journal_title：Oncology letters

authors： Xiao W,He Z,Xing C,Zhen W,Wang S,Lin H

更新日期：2015-12-01 00:00:00

abstract：:Pancreatic cancer is one of the most frequently occurring malignancies worldwide and it is the fourth most common cause of cancer-associated mortality in Western countries. Thalidomide (THD) plays an important role in tumor therapy, as it is able to promote early stage apoptosis and inhibit the process of angiogenesis...

journal_title：Oncology letters

authors： Qiao Z,Yuan J,Shen J,Wang C,He Z,Hu Y,Zhang M,Xu C

更新日期：2015-05-01 00:00:00

abstract：:The use of 5α-reductase inhibitors (5α-RIs) as prostate cancer chemoprevention agents is controversial. Two large randomized trials, the Prostate Cancer Prevention Trial (PCPT) and the Reduction by Dutasteride of Prostate Cancer Events (REDUCE) Trial, have both shown a decreased incidence of prostate cancer in patient...

journal_title：Oncology letters

authors： Lacy JM,Kyprianou N

更新日期：2014-10-01 00:00:00

abstract：:A genetically engineered Salmonella typhimurium strain that may be applied in the medically useful therapeutic strategy of using bacterial agents to target breast cancer in a tumor-bearing nude mouse model has been previously reported. Furthermore, immune cell accumulation in breast tumor types has been observed, part...

journal_title：Oncology letters

authors： Yang M,Xu J,Wang Q,Zhang AQ,Wang K

更新日期：2018-03-01 00:00:00

abstract：:Certain internal malignancies, including colon cancer, can develop endobronchial metastasis. The present study reports a case of colon cancer with superficial-type endobronchial metastases in a 76-year-old male. Chest computed tomography revealed small masses and infiltrates in each lung, with bilateral hilar lymph no...

journal_title：Oncology letters

authors： Kurishima K,Satoh H,Kagohashi K,Miyazaki K,Tamura T,Shiozawa T,Ohara G,Kawaguchi M,Takayashiki N,Hizawa N

更新日期：2014-11-01 00:00:00

abstract：:The aim of this study was to detect methylation of the RAR-β gene in tissues from non-small cell lung cancer (NSCLC) patients. The methylation of the RAR-β gene in DNA from 80 cases with NSCLC and corresponding non-malignant tissues was tested using methylation-specific polymerase chain reaction (PCR; MSP). The result...

journal_title：Oncology letters

authors： Zhao X,Wang N,Zhang M,Xue S,Shi K,Chen Z

更新日期：2012-03-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a type of cancer that is characterized by increased invasiveness, metastatic potential and tumor recurrence. Camptothecin has been demonstrated to exhibit anticancer activity. However, the potential underlying molecular mechanisms mediated by camptothecin in NPC cells remain elusive. ...

journal_title：Oncology letters

authors： Li BS,Huang JY,Guan J,Chen LH

更新日期：2018-07-01 00:00:00

abstract：:Exophthalmos, myxedema and osteoarthropathy (EMO) comprise the triad known as EMO syndrome, which is rarely observed in patients with autoimmune thyroid disease. The present study reports the case of a patient with EMO, including the response of this rare combination to radiotherapy. A 48-year-old patient with EMO syn...

journal_title：Oncology letters

authors： Elsayad K,Kriz J,Bauch J,Scobioala S,Haverkamp U,Sunderkötter C,Eich HT

更新日期：2015-05-01 00:00:00

abstract：:Previous studies have revealed that fibrosis may affect the biological behavior of tumors, however associated research on papillary thyroid microcarcinoma (PTMC) is rare. The aim of the present study was to explore the association between interstitial fibrosis (IF) and the biological behavior of PTMC. In the present s...

journal_title：Oncology letters

authors： Liu X,Zhang S,Gang Q,Shen S,Zhang J,Lun Y,Xu D,Duan Z,Xin S

更新日期：2018-04-01 00:00:00

abstract：:Poly(ADP-Ribose) polymerase family member 9 (PARP9) promotes the proliferation, survival and chemotherapy resistance in lymphoma and prostate cancer. The expression and function of PARP9 in human breast cancer remains unknown. In the present study, it was demonstrated that PARP9 is frequently overexpressed in human br...

journal_title：Oncology letters

authors： Tang X,Zhang H,Long Y,Hua H,Jiang Y,Jing J

更新日期：2018-09-01 00:00:00

abstract：:The current study aimed to explore whether the efficiency of the standard International Prognostic Index (S-IPI), revised-IPI (R-IPI) and enhanced-IPI (NCCN-IPI) in evaluating the prognosis of patients with diffuse large B-cell lymphoma (DLBCL) may be improved by interim 18F-FDG PET/CT. A total of 185 patients with ne...

journal_title：Oncology letters

authors： Jiang M,Chen P,Ruan X,Ye X,Pan Y,Zhang J,Huang Q,Zhou W,Wu H,Wang Q

更新日期：2017-12-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) exhibit an important function in extracellular matrix degradation. MMPs modulate the activation of growth factors, cytokines and metastasis. At present, the effect of exercise on serum levels of MMP-2 and -9 remains unclear. The aim of the present study was to investigate the effect of...

journal_title：Oncology letters

authors： Giganti MG,Tresoldi I,Sorge R,Melchiorri G,Triossi T,Masuelli L,Lido P,Albonici L,Foti C,Modesti A,Bei R

更新日期：2016-09-01 00:00:00

abstract：:A malignant peripheral nerve sheath tumor (MPNST) is defined as any malignant tumor that develops or differentiates from cells in the peripheral nerve sheath. This tumor is commonly associated with neurofibromatosis type 1 (NF1) and previous radiotherapy treatment. Primary intraosseous MPNSTs are extremely rare and a ...

journal_title：Oncology letters

authors： Suzuki K,Yasuda T,Hori T,Watanabe K,Kanamori M,Kimura T

更新日期：2014-06-01 00:00:00

abstract：:The present study aimed to investigate potential recurrence-risk biomarkers based on significant pathways for Luminal A breast cancer through gene expression profile analysis. Initially, the gene expression profiles of Luminal A breast cancer patients were downloaded from The Cancer Genome Atlas database. The differen...

journal_title：Oncology letters

authors： Gao H,Yang M,Zhang X

更新日期：2018-04-01 00:00:00

abstract：:Impairment of microRNA (miRNA) biogenesis may be involved in clear cell renal cell carcinoma (ccRCC). The objective of the present study was to investigate the mRNA levels of important miRNA machinery components, DICER1, DROSHA, DiGeroge syndrome critical region gene 8 (DGCR8), and Argonaute 2 (AGO2), and their correl...

journal_title：Oncology letters

authors： Lee SS,Min H,Ha JY,Kim BH,Choi MS,Kim S

更新日期：2019-10-01 00:00:00

abstract：:Gap junctions (GJs) serve the principal role in the antineoplastic (cytotoxicity and induced apoptosis) effect of chemical drugs. The aim of the present study was to determine the effect of GJ intercellular communication (GJIC) composed of connexin 43 (Cx43) on adriamycin cytotoxicity in breast cancer cells. Four cell...

journal_title：Oncology letters

authors： Jiang G,Dong S,Yu M,Han X,Zheng C,Zhu X,Tong X

更新日期：2017-02-01 00:00:00

abstract：:As a rare hypopharyngeal diverticulum, Killian-Jamieson diverticulum (KJD) is usually incidentally detected, small, asymptomatic and likely to be misdiagnosed as a thyroid nodule. In order to avoid unnecessary treatments resulting from misdiagnosis, principles to distinguish between esophageal diverticula and thyroid ...

journal_title：Oncology letters

authors： Cao L,Ge J,Zhao D,Lei S

更新日期：2016-10-01 00:00:00

abstract：:The objective of the present study was to investigate and analyze the epithelial-cadherin (E-cadherin) expression in invasive ductal carcinoma of the breast, and to analyze the associations between the expression and clinicopathological characteristics of lymph node metastasis and the prognosis of breast cancer. The i...

journal_title：Oncology letters

authors： Yang L,Wang XW,Zhu LP,Wang HL,Wang B,Zhao Q,Wang XY

更新日期：2018-08-01 00:00:00

abstract：:Pro-angiogenic factors [vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF)] and anti-angiogenic factors (endostatin) play important roles in the progression of pancreatic cancer. The purpose of the present study was to investigate the knockdown effect by either VEGF or bFGF siRNA on th...

journal_title：Oncology letters

authors： Yan C,Wang C,Dong M,Liu S,Qi C,Zhao Y

更新日期：2013-03-01 00:00:00

abstract：:Radiofrequency ablation (RFA) and cryoablation are alternative forms of therapy used widely in various pathological states, including treatment of carcinogenesis. The reason is that ablation techniques have ability of modulating the immune system. Furthermore, recent studies have applied this form of therapy on tumor ...

journal_title：Oncology letters

authors： Liu Y,Cao CS,Yu Y,Si YM

更新日期：2016-10-01 00:00:00

abstract：:The expression level and roles of microRNA-497 (miR-497) have been frequently reported in previous studies on cancer. However, its expression, function and associated molecular mechanisms in retinoblastoma remain unknown. In the present study, miR-497 expression levels in human retinoblastoma tissues, normal retinal t...

journal_title：Oncology letters

authors： Li J,Zhang Y,Wang X,Zhao R

更新日期：2017-06-01 00:00:00

abstract：:Activating mutations in the cytosolic serine/threonine kinase, BRAF, have been reported in a variety of neoplasms. BRAF activation may contribute to tumor growth via activation of the MAP/ERK kinase pathway, and BRAF represents a possible therapeutic target. Activating BRAF mutations were recently reported in approxim...

journal_title：Oncology letters

authors： Köllermann J,Albrecht H,Schlomm T,Huland H,Graefen M,Bokemeyer C,Simon R,Sauter G,Wilczak W

更新日期：2010-07-01 00:00:00

abstract：:MicroRNA-181 (miR-181) has been recently demonstrated to participate in the differentiation and development of immune cells, including natural killer cells and B and T lymphocytes, and myeloid linages, including erythroid and megakaryocytic cells. The aberrant expression of miR-181, particularly low expression levels,...

journal_title：Oncology letters

authors： Wang G,Zhao R,Zhao X,Chen XI,Wang D,Jin Y,Liu XI,Zhao CI,Zhu Y,Ren C,Li M,Jin X,Zhang F,Zhong Z,Wang T,Li X

更新日期：2015-11-01 00:00:00

abstract：:The recognition of the biological relevance of long non-coding RNA (lncRNA) molecules has only recently been recognized as one of the most significant advances in contemporary molecular biology. A growing body of evidence indicates that lncRNAs act not only as the intermediary between DNA and protein but also as signi...

journal_title：Oncology letters

authors： Yu X,Li Z

更新日期：2015-10-01 00:00:00

abstract：:The incidence of synchronous multiple primary lung cancer (MPLC) is increasing. However, present diagnostic methods are unable to satisfy the individualized treatment requirements of patients with MPLC. The present study aimed to establish a quantitative mathematical model and analyze its diagnostic value for distingu...

journal_title：Oncology letters

authors： Chen D,Mei L,Zhou Y,Shen C,Xu H,Niu Z,Che G

更新日期：2015-03-01 00:00:00

abstract：:The aim of the present study was to evaluate the clinical importance of melanoma-associated antigen D4 (MAGE-D4) expression in glioma, and to identify it as a valuable prognostic biomarker and therapeutic target. To achieve this, the expression of MAGE-D4 protein in 124 tumor tissues from patients with glioma was meas...

journal_title：Oncology letters

authors： Yan J,Wen J,Wei ZD,Li XS,Li P,Xiao SW

更新日期：2018-04-01 00:00:00

abstract：:Extraosseous osteosarcoma originating from paratesticular soft tissue is an extremely rare type of malignant tumor. With the exception of the present study, only one other case of osteosarcoma originating from paratesticular soft tissue has previously been reported. A 52-year-old man presented with a painless scrotal ...

journal_title：Oncology letters

authors： Hong R,Lee G,Kim H,Kim CS,Kee KH

更新日期：2012-03-01 00:00:00