Interstitial fibrosis in papillary thyroid microcarcinoma and its association with biological behavior.

abstract：:The aim of this study was to ensure a high dose of intensity modulated radiation therapy (IMRT) was delivered to tumor tissue with a low dose to normal organs. Seldinger interventional techniques were used to inject chemotherapy drugs for nasopharyngeal carcinoma (NPC). IMRT was conducted 3 weeks after intervention. P...

journal_title：Oncology letters

authors： Fen X,Qin W,Bao W,Jiang F,Li B,Hu F,Chen X

更新日期：2013-08-01 00:00:00

abstract：:Preoperative radiotherapy improves local disease control and disease-free survival in patients with advanced rectal cancer; however, a reliable predictive biomarker for the effectiveness of irradiation has yet to be elucidated. Phosphorylation of H2A histone family member X (H2AX) to γ-H2AX is induced by DNA double-st...

journal_title：Oncology letters

authors： Kawashima S,Kawaguchi N,Taniguchi K,Tashiro K,Komura K,Tanaka T,Inomata Y,Imai Y,Tanaka R,Yamamoto M,Inoue Y,Lee SW,Kawai M,Tanaka K,Okuda J,Uchiyama K

更新日期：2020-09-01 00:00:00

abstract：:Multiple myeloma (MM) is a hematological malignancy that lacks a cure. However, novel combination therapy is a current anti-MM strategy. Doxorubicin (DOX) is a type of anthracycline which is a first-line chemotherapeutic for treating MM and induces senescence in many types of cancer. Dinaciclib is a potent, small mole...

journal_title：Oncology letters

authors： Tang H,Xu L,Liang X,Gao G

更新日期：2018-11-01 00:00:00

abstract：:Salivary gland carcinomas are rare tumors, representing ~0.5% of all malignancies. Myoepithelioma is also uncommon, representing ~1% of all salivary gland tumors. Myoepithelial carcinoma (MC) is even rarer, representing 0.2 to 0.6% of all salivary gland tumors. We herein report a case of MC with multiple metastases ar...

journal_title：Oncology letters

authors： Panelli Santos KCP,Matsuzaki H,Unetsubo T,Tsuyoshi S,Nagatsuka H,Asaumi JI

更新日期：2017-04-01 00:00:00

abstract：:The aim of this study was to investigate the effect of dexmedetomidine (Dex) on the respiratory function during anesthesia induction in pediatric patients undergoing retinoblastoma (RB) resection. A total of 87 pediatric patients who underwent RB resection in Yidu Central Hospital of Weifang were recruited into this s...

journal_title：Oncology letters

authors： Rong X,Sun C,Zhang F,Zheng J

更新日期：2019-03-01 00:00:00

abstract：:The tumor suppressor protein p53 (TP53) gene is associated with various types of cancer; however, little is known about TP53 expression in patients with childhood acute lymphoblastic leukemia (ALL). The aim of the present study was to investigate the prognostic value of TP53 expression in childhood ALL. To achieve thi...

journal_title：Oncology letters

authors： Weng W,Zhang P,Ruan J,Zhang Y,Ba D,Tang Y

更新日期：2020-01-01 00:00:00

abstract：:Gastric cancer (GC) is a malignant tumor that negatively impacts human health, which typically presents in the advanced stages of disease in the majority of patients. Despite the development of combination chemotherapy, only a modest survival advantage is gained in patients with GC treated by this method. Recently, ca...

journal_title：Oncology letters

authors： Yang L,Wang Y,Wang H

更新日期：2019-12-01 00:00:00

abstract：:The aim of the study was to determine whether interleukin-8 (IL-8) affects human SKOV3 ovarian cancer cell migration and invasion by targeting silencing of IL-8 expression. Silencing small-interfering RNA (siRNA) targeting IL-8 gene was constructed to infect SKOV3 cells by lentiviral vector. The expression of IL-8 and...

journal_title：Oncology letters

authors： Li Y,Liu L,Yin Z,Xu H,Li S,Tao W,Cheng H,Du L,Zhou X,Zhang B

更新日期：2017-02-01 00:00:00

abstract：:Diagnostic value of magnetic resonance imaging (MRI) and multi-slice spiral CT (MSCT) for different pathological stages of prostate cancer was compared. A total of 112 patients with prostate cancer who underwent surgical pathology in The Affiliated Yantai Yuhuangding Hospital of Qingdao University from February 2014 t...

journal_title：Oncology letters

authors： Sui Y,Li J,Zou Z,Shi Y,Hao C

更新日期：2019-06-01 00:00:00

abstract：:Chemotherapy has been widely used in breast cancer therapy, but the efficacy of chemotherapy is intimately associated with the sensitivity of therapeutic drugs to breast cancer. Docetaxel is a first-line chemotherapeutic drug in breast cancer treatment, but further improvement to its efficacy has thus far proved diffi...

journal_title：Oncology letters

authors： Cai Y,Yan X,Zhang G,Zhao W,Jiao S

更新日期：2016-02-01 00:00:00

abstract：:The soluble urokinase-type plasminogen activator receptor (suPAR) and the urokinase-type plasminogen activator receptor (uPAR) have been proposed as useful biomarkers of tumor progression. Recently, suPAR was associated with chemoresistance in lung cancer. However, its clinical significance in leukemia has not previou...

journal_title：Oncology letters

authors： Guo H,Zhou LX,Ma H,Liu B,Cheng J,Ma YY,Zhao L

更新日期：2017-07-01 00:00:00

abstract：:Mosquito coils, which are commonly used as residential insecticides in Asia, contain different concentrations of octachlorodipropyl ether (S-2) as a synergist or an active ingredient. As bis(chloromethyl) ether (BCME) is an extremely potent lung carcinogen that can be produced by the thermolytic degradation of S-2, co...

journal_title：Oncology letters

authors： Zhang J,Qi HW,Sun YP,Xie HK,Zhou CC

更新日期：2015-04-01 00:00:00

abstract：:It is crucial to classify cervical lesions into high-grade squamous intraepithelial lesions (HSILs) and low-grade SILs (LSILs), as LSILs are conservatively treated by observation, based on an expectation of natural regression, whereas HSILs usually require electrosurgical excision. In the present study, peripheral blo...

journal_title：Oncology letters

authors： Zou C,Lyu Y,Jiang J,Cao Y,Wang M,Sang C,Zhang R,Li H,Liew CC,Cheng C,Zhao S

更新日期：2020-09-01 00:00:00

abstract：:Angiosarcoma is a rare and deadly malignancy originating from the vascular endothelial cells. Surgery is the most effective method to cure this disease, but for metastatic angiosarcoma, a chemotherapy-based treatment is the main therapeutic choice. However, there is currently no standard chemotherapy regimen. The curr...

journal_title：Oncology letters

authors： Ye J,Li XF,Wang YD,Yuan Y

更新日期：2015-04-01 00:00:00

abstract：:Breast cancer is the most common malignant disease occurring in women. Conservative breast cancer surgery followed by radiation therapy is currently the standard treatment for this type of cancer. The majority of metastases occur within the scar, which initiated a series of studies. As a result, clinical trials aimed ...

journal_title：Oncology letters

authors： Zaleska K,Przybyła A,Kulcenty K,Wichtowski M,Mackiewicz A,Suchorska W,Murawa D

更新日期：2017-10-01 00:00:00

abstract：:Carcinogenesis is characterized by an abnormal regulation of the cell cycle. Regulators of the cell cycle such as cyclin E play an important role in neoplasia and may be correlated with prognosis. The clinical significance of the expression of cyclin E in stage III colorectal carcinoma has not yet been investigated. T...

journal_title：Oncology letters

authors： Rath-Wolfson L,Bergman M,Ori Y,Goldman A,Ram E,Koren R,Salman H

更新日期：2013-01-01 00:00:00

abstract：:The transcription factor AP-2 β (TFAP2B) serves an important role in kidney development. MicroRNAs (miRNAs) regulate carcinogenic pathways and have gained increasing attention owing to their association with human clear cell renal cell carcinoma (ccRCC) tumorigenesis. However, whether miRNAs could affect renal cell tu...

journal_title：Oncology letters

authors： Zhu M,Zou L,Lu F,Ye L,Su B,Yang K,Lin M,Fu J,Li Y

更新日期：2020-12-01 00:00:00

abstract：:Although Wilms tumor 1 (WT1)-associated protein (WTAP) was initially found to be a specific WT1-binding protein, it has increasingly attracted attention because of its oncogenic role in various types of malignancies, including cholangiocarcinoma, glioblastoma and acute myeloid leukemia. However, the clinical impact of...

journal_title：Oncology letters

authors： Li BQ,Huang S,Shao QQ,Sun J,Zhou L,You L,Zhang TP,Liao Q,Guo JC,Zhao YP

更新日期：2017-04-01 00:00:00

abstract：:Hepatitis B virus × protein (HBx) serves an important role in the pathogenesis of the hepatitis B virus infection. Previous studies have reported that the interaction between HBx and hepatocyte mitochondria is an important factor leading to liver cell injury and apoptosis, ultimately inducing the formation of liver ca...

journal_title：Oncology letters

authors： Ling LR,Zheng DH,Zhang ZY,Xie WH,Huang YH,Chen ZX,Wang XZ,Li D

更新日期：2020-04-01 00:00:00

abstract：:The transient receptor potential melastatin member 8 (TRPM8) is a newly characterized oncoprotein involved in various malignant tumors. However, its expression pattern and biological function in osteosarcoma remain unclear. The present study aimed to explore the expression and prognostic significance of TRPM8 in osteo...

journal_title：Oncology letters

authors： Zhao W,Xu H

更新日期：2016-08-01 00:00:00

abstract：:Pendred syndrome is a rare genetic disease that causes a disturbance in thyroid hormone synthesis, which results in thyroid dysfunction and the development of goiter and sensorineural deafness. The present report describes the case of a young euthyroid male, who developed a large goiter and hearing impairment, despite...

journal_title：Oncology letters

authors： Hu EW,Liu LB,Jiang RY,He XH

更新日期：2014-11-01 00:00:00

abstract：:Imiquimod is an imidazoquinoline immune response modifier that is used in antiviral and antiallergic creams. Combination therapy using transcutaneous imiquimod and oral sorafenib was previously demonstrated to reduce the tumor burden of renal cell carcinoma growing cutaneously in a mouse model. In the present study, a...

journal_title：Oncology letters

authors： Karashima T,Udaka K,Niimura M,Suzuki K,Osakabe H,Shimamoto T,Fukata S,Inoue K,Kuroda N,Seiki M,Shuin T

更新日期：2017-07-01 00:00:00

abstract：:The present study aimed to investigate the effects of the WW domain-containing oxidoreductase (WWOX) gene on the stem cell properties of human ovarian cancer stem cells. A eukaryotic expression vector containing the WWOX gene was transfected into human ovarian cancer stem cells and Western blotting was used to assess ...

journal_title：Oncology letters

authors： Yan HC,Xu J,Fang LS,Qiu YY,Lin XM,Huang HX,Han QY

更新日期：2015-04-01 00:00:00

abstract：:Patients with chronic inflammatory bowel disease have an increased risk of colorectal cancer, and the differentiation between neoplastic and inflammatory lesions often poses a clinical dilemma. The aim of the present study was to investigate whether diffusion-weighted (DW) magnetic resonance (MR) enterography with ult...

journal_title：Oncology letters

authors： Yu H,Feng C,Wang Z,Li J,Wang Y,Hu X,Li Z,Shen Y,Hu D

更新日期：2019-08-01 00:00:00

abstract：:Liver cancer, which is the second leading cause of tumor-associated mortality, is of great concern worldwide due to its resistance to chemotherapeutic drugs. Transcatheter arterial chemoembolization (TACE) has previously been used as a treatment for unresectable liver tumors in China; however, the response to TACE tre...

journal_title：Oncology letters

authors： Liu DX,Li PP,Guo JP,Li LL,Guo B,Jiao HB,Wu JH,Chen JM

更新日期：2019-01-01 00:00:00

abstract：:The aim of this study was to detect methylation of the RAR-β gene in tissues from non-small cell lung cancer (NSCLC) patients. The methylation of the RAR-β gene in DNA from 80 cases with NSCLC and corresponding non-malignant tissues was tested using methylation-specific polymerase chain reaction (PCR; MSP). The result...

journal_title：Oncology letters

authors： Zhao X,Wang N,Zhang M,Xue S,Shi K,Chen Z

更新日期：2012-03-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a type of cancer that is characterized by increased invasiveness, metastatic potential and tumor recurrence. Camptothecin has been demonstrated to exhibit anticancer activity. However, the potential underlying molecular mechanisms mediated by camptothecin in NPC cells remain elusive. ...

journal_title：Oncology letters

authors： Li BS,Huang JY,Guan J,Chen LH

更新日期：2018-07-01 00:00:00

abstract：:Abnormal glucose metabolism is critical in colorectal cancer (CRC) development. Expression of the pyruvate kinase (PK) M2 isoform, rather than the PKM1 isoform, serves important functions in reprogramming the glucose metabolism of cancer cells. Preferential expression of PKM2 is primarily driven by alternative splicin...

journal_title：Oncology letters

authors： Sun Y,Luo M,Chang G,Ren W,Wu K,Li X,Shen J,Zhao X,Hu Y

更新日期：2017-12-01 00:00:00

abstract：:Golgi protein 73 (GP73) is a resident Golgi type II transmembrane protein that has been reported to markedly increase in chronic liver disease, particularly in hepatocellular carcinoma (HCC). However, it remains unclear as to whether serum GP73 represents a reliable serum marker for the diagnosis of HCC. The aim of th...

journal_title：Oncology letters

authors： Hou SC,Xiao MB,Ni RZ,Ni WK,Jiang F,Li XY,Lu CH,Chen BY

更新日期：2013-10-01 00:00:00

abstract：:Ovarian cancer is the most common gynecological malignant cancer in female genitalia. Dysregulation or dysfunction of microRNAs (miRs) contribute to cancer development. The role of miR-520b in ovarian cancer remains unclear. The present study investigated the role of miR-520b in ovarian cancer and determined that the ...

journal_title：Oncology letters

authors： Guan R,Cai S,Sun M,Xu M

更新日期：2017-09-01 00:00:00