Abstract:
:Vasculogenic mimicry (VM), a new pattern of tumor microcirculation, is important for the growth and progression of tumors. Epithelial-mesenchymal transition (EMT) is pivotal in malignant tumor progression and VM formation. With increasing knowledge of cancer stem cell (CSC) phenotypes and functions, increasing evidence suggests that CSCs are involved in VM formation. Recent studies have indicated that EMT is relevant to the acquisition and maintenance of stem cell-like characteristics. Thus, in this review we discuss the correlation between CSCs, EMT and VM formation.
journal_name
Oncol Lettjournal_title
Oncology lettersauthors
Fan YL,Zheng M,Tang YL,Liang XHdoi
10.3892/ol.2013.1555subject
Has Abstractpub_date
2013-11-01 00:00:00pages
1174-1180issue
5eissn
1792-1074issn
1792-1082pii
ol-06-05-1174journal_volume
6pub_type
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