Inhibitory effects of human lactoferrin on U14 cervical carcinoma through upregulation of the immune response.

abstract：:The aim of the present study was to identify genes that may serve as markers for breast cancer prognosis by constructing a gene co-expression network and mining modules associated with survival. Two gene expression datasets of breast cancer were downloaded from ArrayExpress and genes from these datasets with a coeffic...

journal_title：Oncology letters

authors： Shi H,Zhang L,Qu Y,Hou L,Wang L,Zheng M

更新日期：2017-10-01 00:00:00

abstract：:The scavenger receptor stabilin-1 has been reported to be expressed by tumor-associated macrophages (TAMs) and to facilitate tumor growth and metastasis in mouse models of breast carcinoma and melanoma. However, to the best of our knowledge, its expression and association with prognosis in human gastric cancer has not...

journal_title：Oncology letters

authors： Yin SP,Gao Y,Xie XS,Xu DD,Riabov V,Du WD

更新日期：2020-03-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) exhibit an important function in extracellular matrix degradation. MMPs modulate the activation of growth factors, cytokines and metastasis. At present, the effect of exercise on serum levels of MMP-2 and -9 remains unclear. The aim of the present study was to investigate the effect of...

journal_title：Oncology letters

authors： Giganti MG,Tresoldi I,Sorge R,Melchiorri G,Triossi T,Masuelli L,Lido P,Albonici L,Foti C,Modesti A,Bei R

更新日期：2016-09-01 00:00:00

abstract：:Intracranial chondrosarcoma is a rare malignant cartilage-forming tumor, with only a small number of cases in the posterior cranial fossa reported previously. The present study reports the case of a 40-year-old male patient who was admitted to Tianjin Huanhu Hospital with a progressive headache and dizziness that had ...

journal_title：Oncology letters

authors： Chi J,Zhang M,Kang J

更新日期：2016-11-01 00:00:00

abstract：:The clinical use of doxorubicin (DOX), a potent antineoplastic agent, is limited by its serious side-effects, which include acute and chronic cumulative dose-related cardiotoxicity. Berberine (BER), a botanical alkaloid, has been reported to possess cardioprotective and antitumor effects. The 3-(4,5-dimethyl-2-thiazol...

journal_title：Oncology letters

authors： Tong N,Zhang J,Chen Y,Li Z,Luo Y,Zuo H,Zhao X

更新日期：2012-06-01 00:00:00

abstract：:Gallbladder cancer (GBC) is a rare but highly aggressive cancer for which no well-accepted prognostic biomarkers have been identified. Thymus cell antigen 1 (Thy1), also known as cluster of differentiation (CD)90, and integrin α6 (ITGA6), also known as CD49f, are important molecules in cancer and putative markers of v...

journal_title：Oncology letters

authors： Zhang DH,Yang ZL,Zhou EX,Miao XY,Zou Q,Li JH,Liang LF,Zeng GX,Chen SL

更新日期：2016-12-01 00:00:00

abstract：:Cancer is a histologically and genetically heterogeneous population of tumor cells that exhibits distinct molecular profiles determined by epigenetic alterations. P-element-induced wimpy testis (PIWI) proteins in complex with PIWI-interacting RNA (piRNA) have been previously demonstrated to be involved in epigenetic r...

journal_title：Oncology letters

authors： Litwin M,Szczepańska-Buda A,Piotrowska A,Dzięgiel P,Witkiewicz W

更新日期：2017-05-01 00:00:00

abstract：:The putative oncogenic role of ATP/GTP binding protein like 2 (AGBL2) in catalyzing α-tubulin detyrosination has recently been characterized in cancer. However, the status of AGBL2 expression in ovarian cancer and its potential clinical and prognostic significance remain unclear. In the present study, immunohistochemi...

journal_title：Oncology letters

authors： He WP,Wang LL

更新日期：2019-11-01 00:00:00

abstract：:Effect of crizotinib on apoptosis of lung cancer cells was investigated. Human non-small cell lung adenocarcinoma H2228 cells were cultured in the presence of 0, 20, 40, 80, 160 and 320 nmol/l of crizotinib for 3 days, respectively. The inhibition rate of cell proliferation was measured by MTT assay, and half maximal ...

journal_title：Oncology letters

authors： Lu H,Wu S,Chen H,Huang Y,Qiu G,Liu L,Li Y

更新日期：2018-11-01 00:00:00

abstract：:Colorectal cancer (CRC) is the third leading cause of cancer-associated mortalities. Long non-coding RNAs (lncRNAs) have been identified as key regulators in the occurrence and development of CRC. The lncRNA urothelial cancer associated 1 (UCA1) has been demonstrated to promote the development of numerous different ty...

journal_title：Oncology letters

authors： Zhang L,Zheng C,Sun Z,Wang H,Wang F

更新日期：2019-10-01 00:00:00

abstract：:Multiple myeloma is a type of malignancy, which affects the plasma cells of the bone marrow. Recent studies have found that malignant plasma cells may express urokinase plasminogen activator (uPA) and uPA receptor (uPAR), and that initiation of proteolytic events by this system contributes to the process of invasion a...

journal_title：Oncology letters

authors： Shen J,Wang Q,Wang J,Su GH,Wang J,Guo SH,Liu YA,Wu Z,Liu RF,Li X,Guo XJ,Cao J,Zhang YH,Wang ZY

更新日期：2015-10-01 00:00:00

abstract：:Physical activity offers a paradoxical hormetic effect and a health benefit to cancer survivors; however, the biochemical mechanisms have not been entirely elucidated. Despite the well-documented evidence implicating oxidative stress in breast cancer, the association between health benefits and redox status has not be...

journal_title：Oncology letters

authors： Tomasello B,Malfa GA,Strazzanti A,Gangi S,Di Giacomo C,Basile F,Renis M

更新日期：2017-01-01 00:00:00

abstract：:Telomeres are located at the ends of chromosomes and protect them from degradation. Suppressing the activity of telomerase, a telomere-synthesizing enzyme, and maintaining short telomeres is a protective mechanism against cancer in humans. In most human somatic cells, the expression of telomerase reverse transcriptase...

journal_title：Oncology letters

authors： Trybek T,Kowalik A,Góźdź S,Kowalska A

更新日期：2020-08-01 00:00:00

abstract：:The medicinal mushroom Ganoderma lucidum (G. lucidum) has been used for the treatment of various diseases, and is known for the immune-enhancing activity of its polysaccharide. However, little is known about another of its major constituents, triterpene. This study investigated the anticancer mechanism of a triterpene...

journal_title：Oncology letters

authors： Ji Z,Tang Q,Hao R,Zhang J,Pan Y

更新日期：2011-05-01 00:00:00

abstract：:Endotracheal intubation (ETI) and laryngeal mask airway (LMA) in terms of hemodynamics and reaction were compared. A total of 54 general anesthesia patients were randomized into two groups with 27 cases in each group. Acceleration index (ACI), cardiac index (CI), cardiac output (CO), left cardiac work (LCW), systemic ...

journal_title：Oncology letters

authors： Song Z,Tan J,Fang J,Bian Q,Gu L

更新日期：2019-02-01 00:00:00

abstract：:With the growing requirement for novel prognostic biomarkers for pancreatic cancer, many studies have focused on clinical and/or genomic variables. Although many studies have been performed, carbohydrate antigen 19-9 is the only biomarker in clinical use. Therefore, the present study examined whether γ-secretase genes...

journal_title：Oncology letters

authors： Jeon YH,Ha M,Kim SW,Kim MJ,Lee CS,Oh CK,Han ME,Oh SO,Kim YH

更新日期：2019-05-01 00:00:00

abstract：:Follicular lymphoma (FL) occurs primarily in the gastrointestinal tract, with the stomach being one of the rarest sites. According to the literature, <20 cases of primary gastric FL have been reported, with the number of cases with detailed pathological descriptions being even less. The aim of the present study was to...

journal_title：Oncology letters

authors： Na HY,Kim YA,Lee C,Choe JY,Shin SA,Shim JW,Min SK,Kim HJ,Han JH,Kim JE

更新日期：2018-07-01 00:00:00

abstract：:This study investigated energy metabolism and its association with inflammatory cytokines and appetite- regulating hormones in patients with gastrointestinal cancer. Subjects were inpatients scheduled to undergo therapeutic intervention for diagnosed gastrointestinal cancer. Nutritional status on admission was assesse...

journal_title：Oncology letters

authors： Shinsyu A,Bamba S,Kurihara M,Matsumoto H,Sonoda A,Inatomi O,Andoh A,Takebayashi K,Kojima M,Iida H,Tani M,Sasaki M

更新日期：2020-08-01 00:00:00

abstract：:Ubiquitin-conjugating enzyme E2T (UBE2T), a member of the ubiquitin-conjugating E2 family in the ubiquitin-proteasome pathway, has been reported to be overexpressed in certain tumor types and to have an important role in the Fanconi anemia pathway. In the present study, the expression of UBE2T and its association with...

journal_title：Oncology letters

authors： Gong YQ,Peng D,Ning XH,Yang XY,Li XS,Zhou LQ,Guo YL

更新日期：2016-12-01 00:00:00

abstract：:The present study aimed to investigate the effects of Na+/H+ exchanger regulatory factor 1 (NHERF1) gene knockdown, using short-hairpin RNA (shRNA), on the malignant behaviors of prostate cancer cells. A pSuper.puro NHERF1 shRNA vector was transfected into PC-3M prostate cancer cells using Lipofectamine 2000. Stable c...

journal_title：Oncology letters

authors： Ma Q,Jiao Y,Hao Y,Yan S,Lyu N,Gao H,Li D,Liu Q,Zheng J,Song N

更新日期：2016-02-01 00:00:00

abstract：:Exosomes have gained increased research focus due to their key roles as messengers. The components of exosomes include proteins and RNAs that may be horizontally transferred between adjacent or distant cells. Hepatocellular carcinoma (HCC) is among the most malignant types of cancer worldwide, with exosomes implicated...

journal_title：Oncology letters

authors： Wang S,Chen G,Lin X,Xing X,Cai Z,Liu X,Liu J

更新日期：2017-12-01 00:00:00

abstract：:Resveratrol has been reported to inhibit or induce DNA damage, depending upon the type of cell and the experimental conditions. Dietary resveratrol is present in the body predominantly as metabolites and limited data is available concerning the activities of these metabolic products. In the present study, physiologica...

journal_title：Oncology letters

authors： Zunino SJ,Storms DH

更新日期：2017-08-01 00:00:00

abstract：:Central diabetes insipidus (DI) is a rare complication in patients with acute myeloid leukemia (AML), typically occurring in patients with abnormalities of chromosomes 3 or 7. The association between AML with monosomy 7 and DI has been described in a number of studies; however, DI has been rarely reported in cases of ...

journal_title：Oncology letters

authors： Ma H,Yang J,Xiang B,Jia Y

更新日期：2015-06-01 00:00:00

abstract：:Long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is upregulated in numerous types of cancer, and is implicated in various cellular processes associated with cancer progression. However, the underlying molecular mechanisms by which MALAT1 regulates metastasis remain unclear. ...

journal_title：Oncology letters

authors： Zhang Y,Guan X,Wang H,Wang Y,Yue D,Chen R

更新日期：2020-10-01 00:00:00

abstract：:The present study aimed to screen the regulatory mechanism of microRNA (miR/miRNA) typing on gastric cancer cells in gastric cancer tissues. In total, 46 patients who underwent gastric resection in Xiangya Hospital of Central-South University (Changsha, Hunan, China) between January and December 2012 were selected. Ga...

journal_title：Oncology letters

authors： Yang O,Huang J,Lin S

更新日期：2014-08-01 00:00:00

abstract：:The present study aimed to ascertain whether suppression of midkine (MK) expression in pancreatic cancer cells inhibits metastasis to the liver. Human pancreatic cancer AsPC-1 cells were transfected with small interfering RNA (siRNA) targeting MK. siRNA against MK was observed to reduce the expression of MK mRNA and p...

journal_title：Oncology letters

authors： Yu L,Fan Y,Chen B,Hu Y,Gao Y,Wei D

更新日期：2013-11-01 00:00:00

abstract：:Forkhead box protein A1 (FOXA1) is essential for the growth and differentiation of breast epithelium, and has a favorable outcome in breast cancer (BC). Elevated FOXA1 expression in BC also facilitates hormone responsiveness in estrogen receptor (ESR)-positive BC. However, the interaction between these two pathways is...

journal_title：Oncology letters

authors： Chaudhary S,Krishna BM,Mishra SK

更新日期：2017-08-01 00:00:00

abstract：:The aim of the present study was to investigate the expression of transactivation response RNA-binding protein (TARBP)1 and its clinical significance in human non-small-cell lung cancer (NSCLC). TARBP1 expression at the mRNA level was detected by reverse transcription-quantitative polymerase chain reaction (RT-qPCR) i...

journal_title：Oncology letters

authors： Ye J,Wang J,Zhang N,Liu Y,Tan L,Xu L

更新日期：2018-05-01 00:00:00

abstract：:The value of interventional ultrasound in the diagnosis and treatment of submucous myoma of the uterus was assessed to study the ultrasonographic features of modified sonohysterography for submucous polyp of uterus. A total of 25 patients diagnosed preliminarily as submucous myoma of the uterus via conventional ultras...

journal_title：Oncology letters

authors： Liang B,Xie YG,Xu XP,Hu CH

更新日期：2018-05-01 00:00:00

abstract：:The present study evaluated the association between programmed cell death ligand-1 (PD-L1) expression and long-term oncologic outcomes in colorectal cancer (CRC). PD-L1 expression was evaluated using immunohistochemistry in 175 patients who underwent surgical resection for CRC between September 1999 and August 2004. P...

journal_title：Oncology letters

authors： Bae SU,Jeong WK,Baek SK,Kim NK,Hwang I

更新日期：2018-10-01 00:00:00