Abstract：
OBJECTIVES:Little is known about the use of antidementia medications in Australia. Other countries have reported sociodemographic disparities in use. Our objective was to estimate prevalence, duration, and time to initiation of antidementia medication (cholinesterase inhibitors or memantine) among Australians with dementia in residential aged care facilities and to evaluate resident and facility factors associated with use. METHODS:Dynamic retrospective cohort study of people with dementia in 68 residential aged care facilities during 2014 to 2017 using electronic health record and medication administration data. Regression evaluated relationships between medication use (prevalence, duration, and time to initiation) and resident and facility characteristics. RESULTS:Five thousand three hundred fifty-four residents with dementia were included in the analyses. Annual prevalence of antidementia medication use was less than 10% each year and decreased during the study period by 2-percentage points by 2017 (relative to 2014). Antidementia medication use varied by sociodemographic characteristics (3-points lower for single, 4-points lower for divorced relative to married residents, and 3-points higher for Australian-born). Each point in ADL score was associated with 0.1-point lower medication use. Antidementia medication use was lower in outer regional facilities. Most comorbidities were associated with lower antidementia medication use (myocardial infarction, cerebrovascular disease and heart failure 3-points lower, respiratory disease, and diabetes 2-points lower). Age had a complex relationship with antidementia medication use that varied by sex and if medication was started before or after admission. After admission, males initiated antidementia medication earlier than females. CONCLUSIONS:Antidementia medication use in Australian facilities was lower than in other countries and varied by clinical and sociodemographic factors.
journal_name
Int J Geriatr Psychiatryjournal_title
International journal of geriatric psychiatryauthors
Lind KE,Gray LC,Raban MZ,Georgiou A,Westbrook JIdoi
10.1002/gps.5105subject
Has Abstractpub_date
2019-07-01 00:00:00pages
1029-1040issue
7eissn
0885-6230issn
1099-1166journal_volume
34pub_type
杂志文章abstract：BACKGROUND:Psychiatric illness is common in older people in general hospitals, but little is known of the service models operating in the UK, or of the views of old age psychiatrists regarding service provision in this area. We set out to determine the range of UK old age psychiatry service models for older people in g...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.911
更新日期：2003-08-01 00:00:00
abstract：OBJECTIVE:To evaluate the prevalence, clinical features, and comorbidities of restless legs syndrome (RLS) among psychogeriatric patients in an out-patient clinical setting. METHODS:Cross-sectional study of a sample of 100 non-demented psychogeriatric outpatients that were assessed for the presence of RLS using the Re...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.2674
更新日期：2011-12-01 00:00:00
abstract：OBJECTIVES:To compare the frequency and clinical correlates of neuropsychiatric symptoms in patients with Parkinson's disease (PD) with and without dementia and in those with dementia with Lewy bodies (DLB). METHODS:Neuropsychiatric symptoms during the month prior to assessment were assessed in clinically diagnosed PD...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.389
更新日期：2001-05-01 00:00:00
abstract：OBJECTIVE:The purpose of this study is to assess whether atypical antipsychotic drug (AAD) use is associated with increased risk of falling among older (≥65 years) nursing home (NH) residents. METHODS:We conducted a nested case-control study using Resident Assessment Instrument Minimum Data Set 2.0 (RAI-MDS(©)) for NH...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4223
更新日期：2015-08-01 00:00:00
abstract：OBJECTIVE:To determine whether older primary care patients with a Major Depressive Disorder (MDD) have lower heart rate variability (HRV) compared to non-depressed patients. HRV is a measure of cardiac autonomic functioning. METHOD:A cross-sectional comparison of 136 elderly persons with MDD and 136 non-depressed cont...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1439
更新日期：2006-02-01 00:00:00
abstract：OBJECTIVE:Limited data are available on how older adults access public mental health systems. This study examines how uninsured or publicly insured older adults with severe mental illness in San Diego County initially accessed the public mental health system, as well as their subsequent use of public mental health serv...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.2123
更新日期：2009-03-01 00:00:00
abstract：BACKGROUND:Ischaemic vascular dementia shares risk factors with stroke. There is evidence that control of these risk factors may prevent or alter the course of vascular dementia. OBJECTIVE:To assess the effect of regular low-dose aspirin on outcomes for patients with vascular dementia. DESIGN:Retrospective analysis o...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.857
更新日期：2003-05-01 00:00:00
abstract：OBJECTIVES:Cognitive frailty is characterized by the presence of cognitive impairment in exclusion of dementia. In line with other frailty domains, cognitive frailty is associated with negative outcomes. The Comprehensive Frailty Assessment Instrument (CFAI) measures 4 domains of frailty, namely physical, psychological...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4875
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVE:To examine the contribution of medication adherence to 12-month depression scores in the context of other psychosocial and clinical predictors of depression in a sample of older adults treated for depression. METHODS:Secondary analysis of a prospective cohort study involving 241 older patients undergoing dep...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1852
更新日期：2008-02-01 00:00:00
abstract：OBJECTIVES:This study examined the predictive validity of flanker tasks on driving cessation in older drivers. The flanker task comprises a set of response inhibition tests used to assess the ability to suppress responses. METHODS:A total of 2805 older drivers aged ≥65 years at baseline participated in this study. We ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4308
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND:Timely recognition and diagnosis of dementia is the pre-condition for improving dementia care, but diagnosis often occurs late in the disease process. OBJECTIVE:To compare facilitators and obstacles to the timely recognition of dementia across eight European Union states, in order to implement established p...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章,多中心研究
doi：10.1002/gps.1302
更新日期：2005-04-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to examine the association between physical frailty and neurocognitive performance in late-life depression (LLD). METHODS:Cross-sectional design using baseline data from a treatment study of late-life depression was used in this study. Individuals aged 60 years and older were diagno...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4351
更新日期：2016-05-01 00:00:00
abstract：OBJECTIVE:In order to study secular changes in personality factors neuroticism and extroversion, representative population samples of non-demented 75-year-olds underwent psychiatric examinations in 1976-1977 (total n = 223, 138 women, 85 men) and 2005-2006 (total n = 556, 322 women and 234 men). METHODS:Eysenck Person...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.3825
更新日期：2013-03-01 00:00:00
abstract：OBJECTIVES:The purpose of this study was the development of the quality of life (QOL) questionnaire for dementia (QOL-D) in Japan. METHODS:We performed a questionnaire survey of QOL assessment in elderly patients with dementia in Japan, and developed QOL-D. RESULTS:The final version consists of only 31 items grouped ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.711
更新日期：2002-09-01 00:00:00
abstract：BACKGROUND:Systematic evidence became available in the late 1990s on efficacy of cholinesterase inhibitors (CHEIs) for patients with mild to moderate Alzheimer's disease (AD) and they began to be used sporadically. Since January 2001 UK based guidelines indicated that one of three cholinesterase inhibitors (CHEIs) coul...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1720
更新日期：2007-07-01 00:00:00
abstract：BACKGROUND:The relationships between apathy, depression and functional impairment in questionable dementia (QD) and Alzheimer's disease (AD) are complex. This study aimed to explore the interactions between severity of apathy, depression and functional performance; and to investigate the effects of apathy alone, depres...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1694
更新日期：2007-05-01 00:00:00
abstract：OBJECTIVES:Social network (SN) has been known to impact on cognitive function in late life. However, knowledge regarding the link between SN of various types and cognitive decline (CD) is limited. This study's aim was to investigate which types of SN are associated with reduced risk of CD 2 years later among community-...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.5200
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Disturbance of sleep is common in individuals with dementia where there may be reversal of the sleep-wake cycle. People with dementia of the Alzheimer's type have melatonin secretion rhythm disorders. There is some evidence that treatment with exogenous melatonin is an effective treatment for sleep disturban...
journal_title：International journal of geriatric psychiatry
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1002/gps.760
更新日期：2002-12-01 00:00:00
abstract：:Divalproex is now commonly used to treat bipolar disorder in older patients. However, it has yet to be systematically studied in this population. This report describes six older bipolar patients treated with divalproex. Of the six, five showed some improvement with divalproex alone or in combination with other agents....
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/(sici)1099-1166(199906)14:6<494::aid-gps96
更新日期：1999-06-01 00:00:00
abstract：OBJECTIVE:To determine whether donepezil is effective in enhancing cognitive functioning and instrumental activities of daily living (IADLs) in older adults with bipolar disorder. METHODS:Twelve elderly patients with bipolar I or II disorder, with evidence of mild cognitive decrements, were administered donepezil 5-10...
journal_title：International journal of geriatric psychiatry
pub_type： 临床试验,杂志文章
doi：10.1002/gps.1962
更新日期：2008-07-01 00:00:00
abstract：BACKGROUND:The cost-effectiveness of memantine for the treatment of moderate and severe Alzheimer's disease has been assessed in several European countries. Objective of the study was to assess it in Norwegian settings. METHODS:This cost-utility analysis used a Markov modelling approach to simulate the evolution of pa...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.2755
更新日期：2012-06-01 00:00:00
abstract：OBJECTIVE:To study performance of DSM-III-R, ICD-10 and CAMDEX diagnoses of delirium as predictors of improvement in mental state in survivors, and to develop a brief rating scale which will predict reversibility of cognitive dysfunction. DESIGN:Prospective cohort study. SETTING:Acute geriatric inpatient units. PATI...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/(sici)1099-1166(199706)12:6<609::aid-gps55
更新日期：1997-06-01 00:00:00
abstract：OBJECTIVE:To consider the characteristics of first episode psychosis in older adults in a county in North East England. METHOD/DESIGN:The present study used a naturalistic design to compare individuals aged 65 years and over with those under 65, with a first episode psychosis. Data were collected on demographics, diag...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.2437
更新日期：2010-11-01 00:00:00
abstract：BACKGROUND:There is much variation in the services provided for older people with mental health problems. In England, the National Service Framework for Older People (NSFOP) sought to address these inconsistencies and improve care. This study describes the situation three years after its publication. METHODS:A postal ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1662
更新日期：2007-03-01 00:00:00
abstract：OBJECTIVE:This study investigated the reliability and validity of a chronic care facility adaptation of the Clinical Dementia Rating scale (CDR-CC). METHOD:Sixty-two residents in a chronic care facility participated in an inter-rater and 1 month test-retest reliability study. The instrument was validated against the M...
journal_title：International journal of geriatric psychiatry
pub_type： 社论
doi：10.1002/gps.385
更新日期：2001-08-01 00:00:00
abstract：BACKGROUND:This study explored whether patients with late-onset major depressive disorder showed higher carotid artery intima-medium thickness (IMT) and investigated the relationship between the IMT and white matter hyperintensities on magnetic resonance imaging (MRI) among patients. METHODS:Fourteen elderly patients ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1420
更新日期：2006-01-01 00:00:00
abstract：OBJECTIVE:To determine the national prevalence of psychotropic use and association with neuropsychiatric symptoms among patients with dementia. METHODS:Participants diagnosed with dementia (n = 414) in the Aging, Demographics, and Memory Study, a nationally representative survey of US adults >70 years old. Diagnosis w...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4452
更新日期：2017-02-01 00:00:00
abstract：OBJECTIVES:To test whether loneliness is associated with the risk of cognitive impairment up to 11 years later in a European sample of middle-aged and older adults. The study examines whether this association is independent of measures of social isolation, depression, and other risk factors for cognitive impairment and...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.5304
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the contribution of applying the theoretical framework of implementation science for adherence to non-pharmacological interventions to prevent delirium. METHODS:A quasi-experimental prospective design was conducted from March 2017 to October 2018 in a teaching hospital. Participants included 149 ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.5425
更新日期：2021-02-01 00:00:00
abstract：OBJECTIVES:To evaluate the association between the degree of integration in community mental health teams (CMHTs) and: (i) the costs of service provision; (ii) rates of mental health inpatient and care home admission. METHODS:An observational study of service use and admissions to institutional care was undertaken for...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4424
更新日期：2016-11-01 00:00:00
