Divalproex for the treatment of geriatric bipolar disorder.

abstract：RATIONALE:Quetiapine was approved in Germany as an atypical antipsychotic for treatment of schizophrenia in 2000, followed by the approval as an antipsychotic for treatment of bipolar mania in 2003. The approval of quetiapine for treatment of bipolar depression is expected. We hypothesized that the psychogeriatric pres...

journal_title：International journal of geriatric psychiatry

authors： Hilwerling L,Juckel G,Schröder SG

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:The objective of this study is to determine whether resilience is associated with depressive symptoms in geriatric populations. METHOD:A systematic review and meta-analysis were performed (up to March 2015) following the Preferred Reporting Items for Systematic Reviews and Meta-analysis recommendations on th...

journal_title：International journal of geriatric psychiatry

authors： Wermelinger Ávila MP,Lucchetti AL,Lucchetti G

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Little evidence is available about how quality of life (QoL) changes as dementia progresses. OBJECTIVES:We explored QoL trajectories over a 20-month period and examined what predicted change in QoL. METHOD:Fifty-one individuals with a diagnosis of Alzheimer's, vascular or mixed dementia (people with dement...

journal_title：International journal of geriatric psychiatry

authors： Clare L,Woods RT,Nelis SM,Martyr A,Marková IS,Roth I,Whitaker CJ,Morris RG

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:In both dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD), attentional dysfunction is a core clinical feature together with disrupted episodic memory. This study evaluated the cognitive effects of memantine in DLB and PDD using automated tests of attention and episodic memory. METHODS:A ...

journal_title：International journal of geriatric psychiatry

authors： Wesnes KA,Aarsland D,Ballard C,Londos E

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Alzheimer's disease (AD) is prevalent among elderly people, who often have comorbid conditions, and may be prescribed multiple medications. Drug safety and tolerability is paramount in maximising efficacy and optimising patient and carer quality of life, as patients are vulnerable to adverse events (AEs) and/...

journal_title：International journal of geriatric psychiatry

authors： Jones RW

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Several studies have found that low grip strength is associated with dementia in Western populations. However, there have been few studies in Asian populations. This cross-sectional study aimed to examine whether grip strength is independently associated with dementia after controlling for other related fact...

journal_title：International journal of geriatric psychiatry

authors： Shin HY,Kim SW,Kim JM,Shin IS,Yoon JS

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Acetyl Cholinesterase Inhibitors (AChEIs) have been in clinical use for the past five years in the UK for the symptomatic treatment of Alzheimer's disease (AD). There are few data on the patterns and predictors of response to AChEI therapy in routine clinical practice. We therefore investigated clinical vari...

journal_title：International journal of geriatric psychiatry

authors： Pakrasi S,Mukaetova-Ladinska EB,McKeith IG,O'Brien JT

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:The main hypothesis was that subtle vitamin B12 deficiencies occur more commonly in senile dementia of Alzheimer type (SDAT) that in healthy elderly individuals, and may be revealed by elevated total serum homocysteine (tHcy). A subsidiary hypothesis was that such deficiencies would be nutritionally independe...

journal_title：International journal of geriatric psychiatry

authors： McCaddon A,Davies G,Hudson P,Tandy S,Cattell H

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVES:Parental death during childhood, and offspring and spouse death during adulthood have individually been associated with faster cognitive decline and higher Alzheimer's disease (AD) risk in late life. However, the cumulative effect of childhood and adulthood family deaths on AD risk among different age cohort...

journal_title：International journal of geriatric psychiatry

authors： Norton MC,Fauth E,Clark CJ,Hatch D,Greene D,Pfister R,Tschanz JT,Smith KR

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Agitated behaviours among persons with dementia are distressing to both patients and their caregivers. As pharmacological interventions may be limited by their potentially adverse effects, the use of complementary therapies for treatment of agitation has become more popular and aromatherapy is the fastest gr...

journal_title：International journal of geriatric psychiatry

authors： Lin PW,Chan WC,Ng BF,Lam LC

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVES:Recent data suggests that statins have positive effects on cognition in older adults. Studies in patients with mood disorders have found contradicting positive and negative effects of statins on mood and cognition, with limited data in bipolar disorder (BD). The objective of this study was to assess the asso...

journal_title：International journal of geriatric psychiatry

authors： Rej S,Schulte SW,Rajji TK,Gildengers AG,Miranda D,Menon M,Butters MA,Mulsant BH

更新日期：2018-10-01 00:00:00

abstract：:Reduced N-acetyl aspartate (NAA) and increased myo-inositol (MI) levels have been reported in patients with dementia of Alzheimer type (DAT) in comparison with controls. We wished to assess the validity of these findings and to evaluate possible correlations of metabolite proportions with cognitive dysfunction in DAT....

journal_title：International journal of geriatric psychiatry

authors： Heun R,Schlegel S,Graf-Morgenstern M,Tintera J,Gawehn J,Stoeter P

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:To assess the effect of an interdisciplinary educational program in reducing the use of antipsychotics in nursing home residents with dementia. METHODS:We conducted a longitudinal pilot study to test the implementation of a 7-month interdisciplinary educational program in a fixed cohort of residents with dem...

journal_title：International journal of geriatric psychiatry

authors： Monette J,Champoux N,Monette M,Fournier L,Wolfson C,du Fort GG,Sourial N,Le Cruguel JP,Gore B

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the degree to which longitudinal stability of subsyndromal symptoms of depression (SSD) is associated with conversion to dementia in patients with mild cognitive impairment (MCI). METHODS:Data from 405 MCI participants from the Alzheimer's Disease Neuroimaging Initiative (ADNI) study were analyze...

journal_title：International journal of geriatric psychiatry

authors： Mackin RS,Insel P,Aisen PS,Geda YE,Weiner MW,Alzheimer's Disease Neuroimaging Initiative.

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:This study examined the associations of personality characteristics with both subtypes and symptom dimensions of depression in older adults. METHODS:Three hundred and seventy-eight depressed older adults participated in the Netherlands Study of Depression in Older Persons. Personality characteristics were as...

journal_title：International journal of geriatric psychiatry

authors： Koorevaar AML,Hegeman JM,Lamers F,Dhondt ADF,van der Mast RC,Stek ML,Comijs HC

更新日期：2017-12-01 00:00:00

abstract：:A major tenet of gerontological practice and policy has been that community-based services relieve stress on family caregivers and delay or prevent institutionalization of frail elders. Evidence for benefits of community-based services is examined from four perspectives: (1) relief for family caregivers; (2) benefits ...

journal_title：International journal of geriatric psychiatry

authors： Zarit SH,Gaugler JE,Jarrott SE

更新日期：1999-03-01 00:00:00

abstract：:We examined the factor structure of the 17-item Hamilton Rating Scale for Depression (HRS-D) in 206 community-dwelling elderly patients. Using principal components analysis and quartimax rotation, a four-factor structure involving all 17 items and accounting for 57.7% of the variance was desired. The factors represent...

journal_title：International journal of geriatric psychiatry

authors： Onega LL,Abraham IL

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVES:Using a cross-sectional community survey, the authors aimed to estimate the prevalence of dementia among a sample of older Jamaicans and to identify associated demographic factors. METHODS:From February to July 2010, persons of age ≥60 years were randomly selected from two communities in Kingston, Jamaica a...

journal_title：International journal of geriatric psychiatry

authors： Neita SM,Abel WD,Eldemire-Shearer D,James K,Gibson RC

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Despite modest efficacy, unpredictable individual utility, and a high rate of adverse effects, behavioural and psychological symptoms of dementia (BPSD) are common determinants for antipsychotic drug therapy in nursing home patients. AIMS:To explore the impact on BPSD of stopping long-term antipsychotic tre...

journal_title：International journal of geriatric psychiatry

authors： Ruths S,Straand J,Nygaard HA,Aarsland D

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:This study examines the short-term and long-term effects of a cognitive training (CT) program in enhancing cognitive function of older people with subjective memory complaints. METHODS:A single-blind randomized placebo-controlled trial was carried out in a sample of 223 older adults aged 65 years or above wi...

journal_title：International journal of geriatric psychiatry

authors： Kwok TC,Bai X,Li JC,Ho FK,Lee TM

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Depression is a frequent problem in stroke patients but, all too often, the problem goes unrecognized. How depression-like symptoms in post-stroke depression (PSD) should be interpreted is still subject to debate. If PSD has a distinct symptom profile of depression accompanying other chronic vascular somatic...

journal_title：International journal of geriatric psychiatry

authors： Bour A,Rasquin S,Aben I,Strik J,Boreas A,Crijns H,Limburg M,Verhey F

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVES:Social network (SN) has been known to impact on cognitive function in late life. However, knowledge regarding the link between SN of various types and cognitive decline (CD) is limited. This study's aim was to investigate which types of SN are associated with reduced risk of CD 2 years later among community-...

journal_title：International journal of geriatric psychiatry

authors： Kim YB,Lee SH

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Neuropsychiatric symptoms (NPS) are a common feature of Alzheimer's disease (AD), resulting in particular AD endophenotypes. The common AD genetic risk factor apolipoprotein E (APOE) has been suggested underlying these AD endophenotypes. METHODS:APOE genotyping, a comprehensive geriatric assessment (CGA), a...

journal_title：International journal of geriatric psychiatry

authors： D'Onofrio G,Panza F,Seripa D,Sancarlo D,Paris F,Cascavilla L,Urbano M,Gravina C,Fontana A,Solfrizzi V,Pellegrini F,Pilotto A

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare the impact of nortriptyline to sertraline on change in cognitive functioning in depressed older adults. METHODS:We used pre-post neuropsychological data collected as part of a 12-week medication trial comparing sertraline to nortriptyline in the treatment of older adults ...

journal_title：International journal of geriatric psychiatry

authors： Culang-Reinlieb ME,Sneed JR,Keilp JG,Roose SP

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Hoarding disorder (HD) is a chronic and debilitating psychiatric condition. Midlife HD patients have been found to have neurocognitive impairment, particularly in areas of executive functioning, but the extent to which this is due to comorbid psychiatric disorders has not been clear. AIMS/METHOD:The purpose...

journal_title：International journal of geriatric psychiatry

authors： Ayers CR,Wetherell JL,Schiehser D,Almklov E,Golshan S,Saxena S

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Deliberate self harm (DSH) in later life is under researched and is believed to be related to both mental illness and suicide. AIMS:The aim of the study was to examine deliberate self-harm (DSH) in older people presenting to acute hospital services over three years. METHOD:This was a retrospective observat...

journal_title：International journal of geriatric psychiatry

authors： Lamprecht HC,Pakrasi S,Gash A,Swann AG

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:Meta-analyses of antidepressant drug treatment trials have found that increasing age is associated with a less favourable outcome. Because the prevalence of geriatric characteristics, like disability, medical co-morbidity, malnutrition, cognitive (dys)function and frailty increase with age and are associated ...

journal_title：International journal of geriatric psychiatry

authors： Benraad CE,Kamerman-Celie F,van Munster BC,Oude Voshaar RC,Spijker J,Olde Rikkert MG

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The number of elderly combat veterans is steadily increasing in the US and estimates project that a notable percentage of these veterans experience symptoms of posttraumatic stress disorder (PTSD). Limited data exist specifically related to prevalence, assessment, and treatment of PTSD among the elderly vete...

journal_title：International journal of geriatric psychiatry

authors： Owens GP,Baker DG,Kasckow J,Ciesla JA,Mohamed S

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:To determine incidence and risk factors for the development of postoperative acute confusional state (ACS) in the elderly. DESIGN:A prospective cohort study. SETTING:University hospital. PATIENTS:One hundred and five consecutive patients without ACS at baseline who underwent hip surgery because of hip frac...

journal_title：International journal of geriatric psychiatry

authors： Galanakis P,Bickel H,Gradinger R,Von Gumppenberg S,Förstl H

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to examine whether delirium has specific clinical subtypes. METHOD:One hundred and eighty-three elderly subjects meeting DSM-IIIR criteria for delirium were evaluated using a 19-item symptom check-list assessing different dimensions of delirium symptomatology. Exploratory factor ana...

journal_title：International journal of geriatric psychiatry

authors： Camus V,Burtin B,Simeone I,Schwed P,Gonthier R,Dubos G

更新日期：2000-04-01 00:00:00