Differences in heart rate variability between depressed and non-depressed elderly.

Abstract:

OBJECTIVE:To determine whether older primary care patients with a Major Depressive Disorder (MDD) have lower heart rate variability (HRV) compared to non-depressed patients. HRV is a measure of cardiac autonomic functioning. METHOD:A cross-sectional comparison of 136 elderly persons with MDD and 136 non-depressed controls (matched for age and gender) recruited in family practices in the Netherlands. Depression was determined according to the DSM-IV criteria using the PRIME-MD. HRV was measured with an electrocardiogram (ECG) during a 5-minute supine rest. RESULTS:Multivariate analyses showed statistically significant decrease in HRV in MDD patients compared with controls. CONCLUSION:Older primary care patients with MDD have a reduced HRV. This may explain why depression is a risk factor for cardiovascular disease and mortality.

authors

van der Kooy KG,van Hout HP,van Marwijk HW,de Haan M,Stehouwer CD,Beekman AT

doi

10.1002/gps.1439

subject

Has Abstract

pub_date

2006-02-01 00:00:00

pages

147-50

issue

2

eissn

0885-6230

issn

1099-1166

journal_volume

21

pub_type

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