Loneliness is associated with risk of cognitive impairment in the Survey of Health, Ageing and Retirement in Europe.

abstract：BACKGROUND:Systematic evidence became available in the late 1990s on efficacy of cholinesterase inhibitors (CHEIs) for patients with mild to moderate Alzheimer's disease (AD) and they began to be used sporadically. Since January 2001 UK based guidelines indicated that one of three cholinesterase inhibitors (CHEIs) coul...

journal_title：International journal of geriatric psychiatry

authors： Matthews FE,McKeith I,Bond J,Brayne C,MRC CFAS.

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:We investigated cognitive dysfunction in patients with Alzheimer's disease (AD) and amnestic mild cognitive impairment (aMCI) who present hemispheric asymmetries of cerebral metabolic rate of glucose (CMRglc) decrease on (18) F-fluorodeoxyglucose positron emission tomography. METHODS:Based on the hemispheric...

journal_title：International journal of geriatric psychiatry

authors： Murayama N,Ota K,Kasanuki K,Kondo D,Fujishiro H,Fukase Y,Tagaya H,Sato K,Iseki E

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To assess the effect of an interdisciplinary educational program in reducing the use of antipsychotics in nursing home residents with dementia. METHODS:We conducted a longitudinal pilot study to test the implementation of a 7-month interdisciplinary educational program in a fixed cohort of residents with dem...

journal_title：International journal of geriatric psychiatry

authors： Monette J,Champoux N,Monette M,Fournier L,Wolfson C,du Fort GG,Sourial N,Le Cruguel JP,Gore B

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:To evaluate variables associated with quality of life (QOL) in dementia residents in a long-term care facility using a recently standardized and validated dementia-specific QOL scale (ADRQL). METHOD:A cross-sectional, case-control design was employed using validated scales to assess dementia-related symptoma...

journal_title：International journal of geriatric psychiatry

authors： González-Salvador T,Lyketsos CG,Baker A,Hovanec L,Roques C,Brandt J,Steele C

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVE:It is not clear whether the prevalence of psychosis increases with age. We studied the age-specific prevalence of psychotic symptoms in older people in Western Europe. METHODS:Older people without dementia (age 65-104 years, N = 8762) from the western part of Europe in the EURODEP concerted action took part ...

journal_title：International journal of geriatric psychiatry

authors： Östling S,Bäckman K,Waern M,Marlow T,Braam AW,Fichter M,Lawlor BA,Lobos A,Reischies FM,Copeland JR,Skoog I

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:This study investigated the reliability and validity of a chronic care facility adaptation of the Clinical Dementia Rating scale (CDR-CC). METHOD:Sixty-two residents in a chronic care facility participated in an inter-rater and 1 month test-retest reliability study. The instrument was validated against the M...

journal_title：International journal of geriatric psychiatry

authors： Marin DB,Flynn S,Mare M,Lantz M,Hsu MA,Laurans M,Paredes M,Shreve T,Zaklad GR,Mohs RC

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:This study examined changes in cognitive-functional relationships in vascular dementia (VaD) over the course of one year. METHODS:Twenty-four patients with probable VaD were administered the Dementia Rating Scale (DRS). Caregivers completed an informant-based measure of instrumental (IADL) and basic activit...

journal_title：International journal of geriatric psychiatry

authors： Jefferson AL,Cahn-Weiner D,Boyle P,Paul RH,Moser DJ,Gordon N,Cohen RA

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:In the Netherlands, persons of Turkish, Moroccan and Surinamese descent form the largest groups of non-western immigrants. A high prevalence of mild cognitive impairment (MCI) and dementia has been described in immigrant populations in the United States of America and the United Kingdom. We determined the pre...

journal_title：International journal of geriatric psychiatry

authors： Parlevliet JL,Uysal-Bozkir Ö,Goudsmit M,van Campen JP,Kok RM,Ter Riet G,Schmand B,de Rooij SE

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:While activities of daily living are by definition preserved in mild cognitive impairment (MCI), there is evidence of poorer instrumental activities of daily living (IADL) functioning in MCI compared to normal ageing. The aims of the present study were to examine differences in IADL between individuals with M...

journal_title：International journal of geriatric psychiatry

authors： Reppermund S,Sachdev PS,Crawford J,Kochan NA,Slavin MJ,Kang K,Trollor JN,Draper B,Brodaty H

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:To assess the cost effectiveness of cholinesterase inhibitor (ChEI) treatment in patients with Alzheimer's disease (AD) and Dementia with Lewy bodies (DLB). METHOD:We used 4-month open label follow-up data from routine memory clinic patients. There were 852 patients with AD and 112 with DLB. We applied three...

journal_title：International journal of geriatric psychiatry

authors： Gustavsson A,Van Der Putt R,Jönsson L,McShane R

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:To gain insight into caregivers' understanding of the causes of behaviours they find problematic in people with Alzheimer's disease in order to inform the development of educational strategies. METHODS:A qualitative, semi-structured interview was used. Participants were 205 caregivers for a person with Alzhe...

journal_title：International journal of geriatric psychiatry

authors： Paton J,Johnston K,Katona C,Livingston G

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVES:Impaired insight into illness is a prevalent feature of schizophrenia, which negatively influences treatment adherence and clinical outcomes. Little is known about the effects of aging on insight impairment. We aimed to review the available research literature on the effects of aging on insight into illness ...

journal_title：International journal of geriatric psychiatry

authors： Gerretsen P,Plitman E,Rajji TK,Graff-Guerrero A

更新日期：2014-11-01 00:00:00

abstract：:Family members incur substantial financial costs during the course of caring for an individual with Alzheimer's disease. Much of this cost is associated with time spent in caregiving tasks, including supervision and communication with the patient, and assisting with activities of daily living. We have previously repor...

journal_title：International journal of geriatric psychiatry

authors： Marin DB,Dugue M,Schmeidler J,Santoro J,Neugroschl J,Zaklad G,Brickman A,Schnur E,Hoblyn J,Davis KL

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:To examine the effects of risperidone and olanzapine on cognitive functioning in elderly patients with schizophrenia or schizoaffective disorder. METHOD:One hundred seventy-six elderly inpatients and outpatients with schizophrenia or schizoaffective disorder were enrolled in this multicenter, double-blind tr...

journal_title：International journal of geriatric psychiatry

authors： Harvey PD,Napolitano JA,Mao L,Gharabawi G

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:This study aimed to investigate the association of alcohol use disorder (AUD) with four candidate genes in older Korean men: aldehyde dehydrogenase 2 (ALDH2, 1/2), brain-derived neurotrophic factor (BDNF, val66met), serotonin transporter gene linked polymorphic region (5-HTTLPR, s/l), and methylenetetrahydro...

journal_title：International journal of geriatric psychiatry

authors： Shin S,Stewart R,Ferri CP,Kim JM,Shin IS,Kim SW,Yang SJ,Yoon JS

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:Sleep problems and depression are common symptoms in dementia with Lewy bodies (DLB), where patients typically experience subjectively poor sleep quality, fatigue and excessive daytime sleepiness. However, whilst sleep disturbances have been linked to depression, this relationship has not received much attent...

journal_title：International journal of geriatric psychiatry

authors： Elder GJ,Colloby SJ,Lett DJ,O'Brien JT,Anderson KN,Burn DJ,McKeith IG,Taylor JP

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:To examine the level and clinical correlates of aggressive behaviour in Alzheimer's disease (AD). METHOD:Seventy patients with probable AD were rated using validated assessment instruments including the Rating Scale for Aggressive Behaviour in the Elderly (RAGE). RESULTS:Thirty-one subjects were rated as a...

journal_title：International journal of geriatric psychiatry

authors： Gormley N,Rizwan MR,Lovestone S

更新日期：1998-02-01 00:00:00

abstract：OBJECTIVE:Apathy-the most common behavioral disturbance in idiopathic normal pressure hydrocephalus (iNPH)-is associated with poor gait, but the role of apathy on gait improvement after cerebrospinal fluid (CSF) tapping has not been studied yet. This study aims to compare gait improvement after CSF tapping in iNPH pati...

journal_title：International journal of geriatric psychiatry

authors： Allali G,Laidet M,Armand S,Saj A,Krack P,Assal F

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to analyze modifiable factors related to agitation of nursing home residents with dementia. METHODS:Relationship of agitation with three modifiable factors (depression, psychosis, and pain) was explored using longitudinal Minimum Data Set (MDS) information from 2032 residents of Dutc...

journal_title：International journal of geriatric psychiatry

authors： Volicer L,Frijters DH,Van der Steen JT

更新日期：2012-07-01 00:00:00

abstract：:Dementia in community settings is often diagnosed by computerized algorithms. This study examines the extent to which independent diagnosticians agreed among themselves in diagnosing dementia, severity and type when presented with data obtained during a population-based incidence study of cognitive decline and dementi...

journal_title：International journal of geriatric psychiatry

authors： Kay DW,Dewey ME,McKeith IG,O'Cuill M,McCracken C,Fairbairn AF,Harrison R,Illing JC,Hrisos S

更新日期：1998-12-01 00:00:00

abstract：AIMS:The aim of the present study was to examine the factors influencing intentions to seek a cognitive status evaluation among first-degree relatives of persons with Alzheimer's disease. METHODS:Phone interviews were conducted with 93 first-degree relatives of persons with Alzheimer's disease, recruited from a large ...

journal_title：International journal of geriatric psychiatry

authors： Werner P,Heinik J

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVES:To explore the extent of and factors associated with male residents who change wandering status post nursing home admission. DESIGN:Longitudinal design with secondary data analyses. Admissions over a 4-year period were examined using repeat assessments with the Minimum Data Set (MDS) to formulate a model un...

journal_title：International journal of geriatric psychiatry

authors： King-Kallimanis B,Schonfeld L,Molinari VA,Algase D,Brown LM,Kearns WD,Davis DM,Werner DH,Beattie ER,Nelson AL

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Apathy and depression are the most common neuropsychiatric features in Alzheimer's disease (AD). The clinical and functional specific correlates of these syndromes are not well known independently from cognitive deficits and other behavioral disturbances. MATERIAL AND METHODS:Six hundred and eighty-six pati...

journal_title：International journal of geriatric psychiatry

authors： Benoit M,Andrieu S,Lechowski L,Gillette-Guyonnet S,Robert PH,Vellas B,REAL-FR group.

更新日期：2008-04-01 00:00:00

abstract：:This review presents evidence of the undertreatment of pain for people with cognitive impairment and explores reasons for this, emphasizing inadequate detection due to lack of suitable pain assessment protocols. Implications for practice and suggestions for further research are made. ...

journal_title：International journal of geriatric psychiatry

authors： Cook AK,Niven CA,Downs MG

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVES:Family dementia caregivers are at high risk of depression and burnout. We assessed the feasibility of Central Meditation and Imagery Therapy for Caregivers (CMIT-C), a novel 8-week group meditation and guided imagery group therapy program, for dementia caregivers reporting stress because of caregiving respon...

journal_title：International journal of geriatric psychiatry

authors： Jain FA,Nazarian N,Lavretsky H

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Nowadays, there is an increasing interest in the heritable aspects of Alzheimer's Disease (AD). The ethical implications of this kind of research are also attracting attention. However, relatively few open-ended qualitative studies have been carried out to study these aspects. OBJECTIVE:To explore and analy...

journal_title：International journal of geriatric psychiatry

authors： van der Vorm A,Rikkert MO,Vernooij-Dassen M,Dekkers W,EDCON Panel.

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Despite being simple and cheap, the EEG is not often used in clinical practice. METHODOLOGY:Literature search using PUBMED and Medline. RESULTS:Quantitative EEG can help to identify mild dementia and mild cognitive impairment and can increase diagnostic accuracy when used with other imaging techniques. EEG...

journal_title：International journal of geriatric psychiatry

authors： Adamis D,Sahu S,Treloar A

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Agitated behaviours among persons with dementia are distressing to both patients and their caregivers. As pharmacological interventions may be limited by their potentially adverse effects, the use of complementary therapies for treatment of agitation has become more popular and aromatherapy is the fastest gr...

journal_title：International journal of geriatric psychiatry

authors： Lin PW,Chan WC,Ng BF,Lam LC

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:The aims of this study were to explore the knowledge, attitudes and beliefs that nursing home managers hold with regard to the assessment and management of pain in residents with dementia and to determine how these may be affected by the demographic characteristics of the respondents. METHODS:A questionnair...

journal_title：International journal of geriatric psychiatry

authors： Barry HE,Parsons C,Peter Passmore A,Hughes CM

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) causes progressive loss of memory and disability, especially in older people. As worldwide population grows older, AD is responsible for an important social and economical burden in many nations. People suffering from AD may experience health-related stigma that influences their atti...

journal_title：International journal of geriatric psychiatry

authors： Piver LC,Nubukpo P,Faure A,Dumoitier N,Couratier P,Clément JP

更新日期：2013-09-01 00:00:00