Psychotropic use and associated neuropsychiatric symptoms among patients with dementia in the USA.

abstract：OBJECTIVE:We investigated the frequency and inter-relationship of neuropsychiatric disturbances in a population sample of persons suffering from Alzheimer's disease (AD). METHOD:Screening 5,092 elderly residents (90% of the population aged 65 and older) of Cache County, Utah, for dementia, we identified 198 persons wi...

journal_title：International journal of geriatric psychiatry

authors： Lyketsos CG,Sheppard JM,Steinberg M,Tschanz JA,Norton MC,Steffens DC,Breitner JC

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to evaluate the effect of tumour necrosis factor-alpha inhibitors (TNF-αI) on Alzheimer's disease-associated pathology. DESIGN:A literature search of PubMed, Embase, PsychINFO, Web of Science, Scopus, and the Cochrane Library databases for human and animal studies that evalua...

journal_title：International journal of geriatric psychiatry

authors： Ekert JO,Gould RL,Reynolds G,Howard RJ

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:Meta-analyses of antidepressant drug treatment trials have found that increasing age is associated with a less favourable outcome. Because the prevalence of geriatric characteristics, like disability, medical co-morbidity, malnutrition, cognitive (dys)function and frailty increase with age and are associated ...

journal_title：International journal of geriatric psychiatry

authors： Benraad CE,Kamerman-Celie F,van Munster BC,Oude Voshaar RC,Spijker J,Olde Rikkert MG

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate mortality and causes of death in older patients with schizophrenia in comparison with the general population. The mortality of patients experiencing relapse was also compared with those in remission. METHODS:The study sample consists of patients (n = 9461) over 65 years ...

journal_title：International journal of geriatric psychiatry

authors： Talaslahti T,Alanen HM,Hakko H,Isohanni M,Häkkinen U,Leinonen E

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:Modifiable risk factors for dementia were recently identified and compiled in a systematic review. The 'Lifestyle for Brain Health' (LIBRA) score, reflecting someone's potential for dementia prevention, was studied in a large longitudinal population-based sample with respect to predicting cognitive change ove...

journal_title：International journal of geriatric psychiatry

authors： Schiepers OJG,Köhler S,Deckers K,Irving K,O'Donnell CA,van den Akker M,Verhey FRJ,Vos SJB,de Vugt ME,van Boxtel MPJ

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Psychosis, like other neuropsychiatric symptoms of dementia, has many features that make predictive modeling of its onset difficult. For example, psychosis onset is associated with both the absolute degree of cognitive impairment and the rate of cognitive decline. Moreover, psychotic symptoms, while more like...

journal_title：International journal of geriatric psychiatry

authors： Seltman HJ,Mitchell S,Sweet RA

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:Our aim was to evaluate the effectiveness of a modified 8-week reminiscence therapy on the burden, positive experience, and life satisfaction of older spouse caregivers and the life satisfaction of stroke survivors. METHODS:We conducted a randomized controlled trial by using 75 older stroke couples recruited...

journal_title：International journal of geriatric psychiatry

authors： Mei Y,Lin B,Li Y,Ding C,Zhang Z

更新日期：2018-04-01 00:00:00

abstract：PURPOSE:In this study, we explored association between hypertension and depression in the very elderly using a sample ranged in age from 90 to 108 years. METHODS:A cross-sectional study. RESULTS:The sample included 687 unrelated Chinese nonagenarians/centenarians (67.4% women, mean age 93.51 years). The mean depressi...

journal_title：International journal of geriatric psychiatry

authors： Wen Z,Bi-Rong D,Chang-Quan H,Zhen-Chan L,Yuan Z,Hong-Mei W,Yan-Ling Z,Hui W,Ping H

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the short-term tolerability of two titration schedules of sublingual asenapine in older patients with psychosis, not associated with organic brain disease, and to compare asenapine pharmacokinetics in older patients versus younger adults with schizophrenia. METHODS:Patien...

journal_title：International journal of geriatric psychiatry

authors： Dubovsky SL,Frobose C,Phiri P,de Greef R,Panagides J

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Depression is a frequent problem in stroke patients but, all too often, the problem goes unrecognized. How depression-like symptoms in post-stroke depression (PSD) should be interpreted is still subject to debate. If PSD has a distinct symptom profile of depression accompanying other chronic vascular somatic...

journal_title：International journal of geriatric psychiatry

authors： Bour A,Rasquin S,Aben I,Strik J,Boreas A,Crijns H,Limburg M,Verhey F

更新日期：2009-10-01 00:00:00

abstract：:As an elder's functional impairment increases, so in general does the tendency for the caregiver to intervene in the elder's daily activities and initiatives. To a certain extent, such intervention is necessary to compensate for the elder's loss of independent ability, and without such intervention, adverse outcomes f...

journal_title：International journal of geriatric psychiatry

authors： Fulmer T,Gurland B

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Depression is common in Alzheimer's disease (AD; 5-35%). It is associated with increased disability, cost of care and carer burden. Exercise is known to be associated with a lower prevalence of depression across the age range but little is known about its relationship to depression in AD. AIMS:To investigat...

journal_title：International journal of geriatric psychiatry

authors： Regan C,Katona C,Walker Z,Livingston G

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:Memory complaints in the absence of objective test impairments are common. Only a subset of these subjects seeks medical attention for these complaints. The aim of the present study was to investigate which factors determine why people with subjective memory complaints (SMC) seek medical attention. METHODS:T...

journal_title：International journal of geriatric psychiatry

authors： Ramakers IH,Visser PJ,Bittermann AJ,Ponds RW,van Boxtel MP,Verhey FR

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:The objective of this study is to clarify if admission to a specialist geriatric medicine ward leads to improvements in aspects of acute medical care for patients with dementia. METHODS:We analysed combined data involving 900 patients from the Irish and Northern Irish audits of dementia care. Data on baselin...

journal_title：International journal of geriatric psychiatry

authors： Briggs R,O'Shea E,de Siún A,O'Neill D,Gallagher P,Timmons S,Kennelly S

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:The aims of this study were to explore the knowledge, attitudes and beliefs that nursing home managers hold with regard to the assessment and management of pain in residents with dementia and to determine how these may be affected by the demographic characteristics of the respondents. METHODS:A questionnair...

journal_title：International journal of geriatric psychiatry

authors： Barry HE,Parsons C,Peter Passmore A,Hughes CM

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVES:We explored relationships between general religiousness, positive religious coping, negative religious coping (spiritual struggle), and affective symptoms among geriatric mood disordered outpatients, in the northeastern USA. METHODS:We assessed for general religiousness (religious affiliation, belief in God...

journal_title：International journal of geriatric psychiatry

authors： Rosmarin DH,Malloy MC,Forester BP

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVES:Little research has explored how cognitive function and activities of daily living (ADL) affect each other over time. In addition, no current finding provides a clear hint to the temporal precedence between them. The present study tries to address these limitations of prior studies by utilizing a longitudina...

journal_title：International journal of geriatric psychiatry

authors： Wang J,Zhu WH,Li YF,Zhu WW

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Despite being simple and cheap, the EEG is not often used in clinical practice. METHODOLOGY:Literature search using PUBMED and Medline. RESULTS:Quantitative EEG can help to identify mild dementia and mild cognitive impairment and can increase diagnostic accuracy when used with other imaging techniques. EEG...

journal_title：International journal of geriatric psychiatry

authors： Adamis D,Sahu S,Treloar A

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVES:Suicide in older adults is a major public health issue. Past research across the US adult population has linked prescription medication misuse with suicidal ideation. No work has evaluated associations between prescription opioid or benzodiazepine misuse and suicidal ideation in older adults, and this work a...

journal_title：International journal of geriatric psychiatry

authors： Schepis TS,Simoni-Wastila L,McCabe SE

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:Apathy is one of the most frequent symptoms of dementia, whose underlying neurobiology is not well understood. The objective was to analyze the correlations of apathy and its dimensions with gray and white matter damage in the brain of patients with advanced Alzheimer's disease (AD). METHODS:The setting of t...

journal_title：International journal of geriatric psychiatry

authors： Agüera-Ortiz L,Hernandez-Tamames JA,Martinez-Martin P,Cruz-Orduña I,Pajares G,López-Alvarez J,Osorio RS,Sanz M,Olazarán J

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:In the last decade, repetitive transcranial magnetic stimulation (rTMS) has been introduced as a non-invasive neuromodulation therapy for depression. Little is known, however, about (serious) adverse events (AE) of rTMS in older adults with a depression. In this article, we want to study what is known about (...

journal_title：International journal of geriatric psychiatry

authors： Overvliet GM,Jansen RAC,van Balkom AJLM,van Campen DC,Oudega ML,van der Werf YD,van Exel E,van den Heuvel OA,Dols A

更新日期：2020-10-09 00:00:00

abstract：BACKGROUND:The paper explores the diverse ethical issues in the care of persons with dementia, in the Netherlands and Kerala, India. These cross-cultural data are used to suggest newer ways for addressing the ethical issues in a mutually enhancing manner. METHODS:A thorough review of the literature focusing on ethical...

journal_title：International journal of geriatric psychiatry

authors： Sowmini CV,De Vries R

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To compare performance of patients with mild-moderate Alzheimer's disease (AD) and vascular dementia (VaD) on tests of executive functioning and working memory. METHODS:Patients with AD (n = 76) and VaD (n = 46) were recruited from a memory clinic along with dementia free participants (n = 28). They underwen...

journal_title：International journal of geriatric psychiatry

authors： McGuinness B,Barrett SL,Craig D,Lawson J,Passmore AP

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVES:Patient expectations of treatment effects could influence neuropsychological and clinical outcomes in clinical trials of behavioral and lifestyle interventions, which could potentially confound the interpretation of findings. Our aim was to examine whether patient expectancy mediated effectiveness of Mindful...

journal_title：International journal of geriatric psychiatry

authors： Haddad R,Lenze EJ,Nicol G,Miller JP,Yingling M,Wetherell JL

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVES:Antidepressant use is often reported as a risk factor for Orthostatic Hypotension (OH), however this relationship has never been explored in those with mild/moderate Alzheimer Disease (AD), who may represent a particularly vulnerable cohort. METHODS:We performed a cross-sectional analysis of baseline data f...

journal_title：International journal of geriatric psychiatry

authors： Dyer AH,Murphy C,Briggs R,Lawlor B,Kennelly SP,NILVAD Study Group.

更新日期：2020-11-01 00:00:00

abstract：:Residents of nursing and residential homes are often prescribed medication for physical and mental ill-health with resultant polypharmacy and the possibility of iatrogenic disorders. Sometimes drugs are prescribed inappropriately and a number of studies have highlighted the overuse of psychotropic drugs. Legislation i...

journal_title：International journal of geriatric psychiatry

authors： Furniss L,Craig SK,Burns A

更新日期：1998-07-01 00:00:00

abstract：:Alzheimer's disease (AD) affects millions of people worldwide and the number of AD cases will increase with increased life expectancy. Today there is no cure for this devastating and always lethal disease and therefore it is of great interest for patients, relatives and societies to find new drugs that can hinder the ...

journal_title：International journal of geriatric psychiatry

authors： Ankarcrona M,Winblad B

更新日期：2005-02-01 00:00:00

abstract：RATIONALE:Quetiapine was approved in Germany as an atypical antipsychotic for treatment of schizophrenia in 2000, followed by the approval as an antipsychotic for treatment of bipolar mania in 2003. The approval of quetiapine for treatment of bipolar depression is expected. We hypothesized that the psychogeriatric pres...

journal_title：International journal of geriatric psychiatry

authors： Hilwerling L,Juckel G,Schröder SG

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Mild Cognitive Impairment (MCI) is a borderline state between age-associated cognitive decline and mild dementia. MCI is separated from mild dementia by an absence of global intellectual deterioration and the preservation of activities of daily living (ADL). However, even mild degrees of cognitive deteriorat...

journal_title：International journal of geriatric psychiatry

authors： Perneczky R,Pohl C,Sorg C,Hartmann J,Tosic N,Grimmer T,Heitele S,Kurz A

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:Neuropsychological test batteries are administered in person to assess cognitive function in both clinical and research settings. However, in-person administration holds a number of logistical challenges that makes it difficult to use in large or remote populations or for multiple serial assessments over time...

journal_title：International journal of geriatric psychiatry

authors： Bunker L,Hshieh TT,Wong B,Schmitt EM,Travison T,Yee J,Palihnich K,Metzger E,Fong TG,Inouye SK

更新日期：2017-09-01 00:00:00