Lifestyle for Brain Health (LIBRA): a new model for dementia prevention.

abstract：OBJECTIVES:Recent data suggests that statins have positive effects on cognition in older adults. Studies in patients with mood disorders have found contradicting positive and negative effects of statins on mood and cognition, with limited data in bipolar disorder (BD). The objective of this study was to assess the asso...

journal_title：International journal of geriatric psychiatry

authors： Rej S,Schulte SW,Rajji TK,Gildengers AG,Miranda D,Menon M,Butters MA,Mulsant BH

更新日期：2018-10-01 00:00:00

abstract：:Residents of nursing and residential homes are often prescribed medication for physical and mental ill-health with resultant polypharmacy and the possibility of iatrogenic disorders. Sometimes drugs are prescribed inappropriately and a number of studies have highlighted the overuse of psychotropic drugs. Legislation i...

journal_title：International journal of geriatric psychiatry

authors： Furniss L,Craig SK,Burns A

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to assess the measurement properties of the self-reported Patient Health Questionnaire-9 (PHQ-9) and its 10-item observer version (PHQ-10OV) among nursing home residents. METHODS:We conducted a retrospective study of Minimum Data Set 3.0 assessments for national cohorts of Me...

journal_title：International journal of geriatric psychiatry

authors： Bélanger E,Thomas KS,Jones RN,Epstein-Lubow G,Mor V

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To examine the relationship between care management arrangements and the Care Programme Approach (CPA) in the context of old age mental health services and, particularly, dementia services. METHOD:The information reported is from a national study of care management arrangements, funded by the Department of H...

journal_title：International journal of geriatric psychiatry

authors： Hughes J,Stewart K,Challis D,Darton R,Weiner K

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:The management of Behavioural and Psychological Symptoms of Dementia (BPSD) has been the subject of considerable debate over the last few years in view of the poor evidence base for pharmacological agents and concerns about their safety. OBJECTIVES:This study sought to obtain expert opinion on the managemen...

journal_title：International journal of geriatric psychiatry

authors： Bishara D,Taylor D,Howard RJ,Abdel-Tawab R

更新日期：2009-09-01 00:00:00

abstract：PURPOSE:In this study, we explored association between hypertension and depression in the very elderly using a sample ranged in age from 90 to 108 years. METHODS:A cross-sectional study. RESULTS:The sample included 687 unrelated Chinese nonagenarians/centenarians (67.4% women, mean age 93.51 years). The mean depressi...

journal_title：International journal of geriatric psychiatry

authors： Wen Z,Bi-Rong D,Chang-Quan H,Zhen-Chan L,Yuan Z,Hong-Mei W,Yan-Ling Z,Hui W,Ping H

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To assess the cost effectiveness of cholinesterase inhibitor (ChEI) treatment in patients with Alzheimer's disease (AD) and Dementia with Lewy bodies (DLB). METHOD:We used 4-month open label follow-up data from routine memory clinic patients. There were 852 patients with AD and 112 with DLB. We applied three...

journal_title：International journal of geriatric psychiatry

authors： Gustavsson A,Van Der Putt R,Jönsson L,McShane R

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:Previous studies have reported depressive symptoms in the preclinical stages of Alzheimer's disease (AD). The objective of this study was to determine whether depressive symptoms are associated with cortical amyloid burden. In order to do this, we measured cortical amyloid via (11) C-labeled Pittsburgh Compou...

journal_title：International journal of geriatric psychiatry

authors： Yasuno F,Kazui H,Morita N,Kajimoto K,Ihara M,Taguchi A,Yamamoto A,Matsuoka K,Kosaka J,Kudo T,Iida H,Kishimoto T,Nagatsuka K

更新日期：2016-08-01 00:00:00

abstract：OBJECTS:Identification of biomarkers for Alzheimer's disease (AD) is important for its early diagnosis and prevention and a key in advancing our understanding of its pathophysiology. The aim of this study was to determine whether systemic inflammatory interleukin-1ß (IL-1ß) and interleukin-6 (IL-6) as well as hypertens...

journal_title：International journal of geriatric psychiatry

authors： Honma T,Hatta K,Hitomi Y,Kambayashi Y,Hibino Y,Konoshita T,Nakamura H

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Apathy is defined as an important loss of motivation in all domains of daily functioning. Especially in old age, apathy might be a specific neuropsychiatric syndrome separate from depression. There are indications that apathy in elderly subjects is related to vascular disease. OBJECTIVE:To assess the relati...

journal_title：International journal of geriatric psychiatry

authors： van der Mast RC,Vinkers DJ,Stek ML,Bek MC,Westendorp RG,Gussekloo J,de Craen AJ

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Neuropathological studies suggest that the association between neurodegenerative brain damage and clinical symptoms may be stronger in women than in men; therefore women are more likely to express neurodegeneration as clinical dementia. Furthermore, a recent 18F-FDG PET study explored gender differences in t...

journal_title：International journal of geriatric psychiatry

authors： Perneczky R,Diehl-Schmid J,Förstl H,Drzezga A,Kurz A

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Morbidity among elderly people has an important influence on their psychological well-being. Evaluation of the morbidity profile and its determinants, which have implications for management of medical problems of elderly people, are scarce in developing countries. Even the physicians' detection rate of menta...

journal_title：International journal of geriatric psychiatry

authors： Prakash O,Gupta LN,Singh VB,Singhal AK,Verma KK

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:Little research has explored how cognitive function and activities of daily living (ADL) affect each other over time. In addition, no current finding provides a clear hint to the temporal precedence between them. The present study tries to address these limitations of prior studies by utilizing a longitudina...

journal_title：International journal of geriatric psychiatry

authors： Wang J,Zhu WH,Li YF,Zhu WW

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:In recent years, there has been a blossoming of studies examining cerebrospinal fluid (CSF) as a method of studying the pathophysiology of delirium. We systematically reviewed the literature for CSF studies in delirium and provide here a summary of the implications for our understanding of delirium pathophysi...

journal_title：International journal of geriatric psychiatry

authors： Hall RJ,Watne LO,Cunningham E,Zetterberg H,Shenkin SD,Wyller TB,MacLullich AMJ

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the degree to which longitudinal stability of subsyndromal symptoms of depression (SSD) is associated with conversion to dementia in patients with mild cognitive impairment (MCI). METHODS:Data from 405 MCI participants from the Alzheimer's Disease Neuroimaging Initiative (ADNI) study were analyze...

journal_title：International journal of geriatric psychiatry

authors： Mackin RS,Insel P,Aisen PS,Geda YE,Weiner MW,Alzheimer's Disease Neuroimaging Initiative.

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:To determine the prevalence of body image dysfunction in a cohort of older, inpatient women, and to examine any associated health or sociodemographic factors. METHODS:In this cross-sectional, observational study, 50 older women admitted to a subacute hospital completed the Body Shape Questionnaire (BSQ-34),...

journal_title：International journal of geriatric psychiatry

authors： Dean E,Haywood C,Hunter P,Austin N,Prendergast L

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare the impact of nortriptyline to sertraline on change in cognitive functioning in depressed older adults. METHODS:We used pre-post neuropsychological data collected as part of a 12-week medication trial comparing sertraline to nortriptyline in the treatment of older adults ...

journal_title：International journal of geriatric psychiatry

authors： Culang-Reinlieb ME,Sneed JR,Keilp JG,Roose SP

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:Several potentially modifiable risk factors for cognitive decline and dementia have been identified, including low educational attainment, smoking, diabetes, physical inactivity, hypertension, midlife obesity, depression, and perceived social isolation. Managing these risk factors in late midlife and older ag...

journal_title：International journal of geriatric psychiatry

authors： Huntley J,Corbett A,Wesnes K,Brooker H,Stenton R,Hampshire A,Ballard C

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:Among dementia professionals in several European countries, it is believed that dementia is under-diagnosed and under-treated to a greater extent among ethnic minorities than in the native population. It is unknown whether this belief holds true. The objective of this study was to compare the prevalence of re...

journal_title：International journal of geriatric psychiatry

authors： Nielsen TR,Vogel A,Phung TK,Gade A,Waldemar G

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to analyze modifiable factors related to agitation of nursing home residents with dementia. METHODS:Relationship of agitation with three modifiable factors (depression, psychosis, and pain) was explored using longitudinal Minimum Data Set (MDS) information from 2032 residents of Dutc...

journal_title：International journal of geriatric psychiatry

authors： Volicer L,Frijters DH,Van der Steen JT

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVES:Suicide in older adults is a major public health issue. Past research across the US adult population has linked prescription medication misuse with suicidal ideation. No work has evaluated associations between prescription opioid or benzodiazepine misuse and suicidal ideation in older adults, and this work a...

journal_title：International journal of geriatric psychiatry

authors： Schepis TS,Simoni-Wastila L,McCabe SE

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Scales measuring cognitive and executive functions are integral to the assessment and management of patients with suspected cognitive impairment. Some of the most commonly used cognitive tests are now subject to copyright restrictions. Furthermore, no existing scale assesses both executive and cognitive abil...

journal_title：International journal of geriatric psychiatry

authors： Burns A,Harrison JR,Symonds C,Morris J

更新日期：2020-10-29 00:00:00

abstract：OBJECTIVE:To evaluate the frequency of and determine predictive factors for acute hospitalization in a prospective study of patients with Alzheimer's disease (AD). DESIGN:A one year prospective study. PARTICIPANTS:134 patients recruited from the memory clinic in Toulouse University Hospital, with AD diagnosed using t...

journal_title：International journal of geriatric psychiatry

authors： Andrieu S,Reynish E,Nourhashemi F,Shakespeare A,Moulias S,Ousset PJ,Sagnier P,Richard A,Albarede JL,Vellas B

更新日期：2002-05-01 00:00:00

abstract：:Alzheimer's disease (AD) affects millions of people worldwide and the number of AD cases will increase with increased life expectancy. Today there is no cure for this devastating and always lethal disease and therefore it is of great interest for patients, relatives and societies to find new drugs that can hinder the ...

journal_title：International journal of geriatric psychiatry

authors： Ankarcrona M,Winblad B

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Neuropsychiatric symptoms (NPS) are a common feature of Alzheimer's disease (AD), resulting in particular AD endophenotypes. The common AD genetic risk factor apolipoprotein E (APOE) has been suggested underlying these AD endophenotypes. METHODS:APOE genotyping, a comprehensive geriatric assessment (CGA), a...

journal_title：International journal of geriatric psychiatry

authors： D'Onofrio G,Panza F,Seripa D,Sancarlo D,Paris F,Cascavilla L,Urbano M,Gravina C,Fontana A,Solfrizzi V,Pellegrini F,Pilotto A

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to examine whether the reversal of compromised regional cerebral blood flow (rCBF) in older patients with major depressive disorder (MDD) is dependent on specific parameters of selective serotonin reuptake inhibitor (SSRI) treatment and to examine the efficacy of such treatment. ...

journal_title：International journal of geriatric psychiatry

authors： Hanada H,Imanaga J,Yoshiiwa A,Yoshikawa T,Tanaka Y,Tsuru J,Inoue A,Ishitobi Y,Okamoto S,Kanehisa M,Maruyama Y,Ninomiya T,Higuma H,Isogawa K,Kawasaki T,Fujioka T,Akiyoshi J

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVES:Dementia is the most common neurological disease in older adults; headaches, including migraines, are the most common neurological disorder across all ages. The objective of this study was to explore the relationship between migraines and dementia, including Alzheimer's disease (AD) and vascular dementia (Va...

journal_title：International journal of geriatric psychiatry

authors： Morton RE,St John PD,Tyas SL

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:There is limited literature around peer research in dementia. This study aims to identify the benefits, the risks and the practical challenges and to develop a model of good practice in peer research with people with dementia. METHODS:We searched on PsycInfo, PubMed and Google Scholar for empirical investig...

journal_title：International journal of geriatric psychiatry

authors： Di Lorito C,Birt L,Poland F,Csipke E,Gove D,Diaz-Ponce A,Orrell M

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:To examine whether psychogeriatric admissions increased after COVID-19, independent of seasonal variation; whether the increase was comparable with that seen in severe acute respiratory syndrome (SARS); and which factors were associated with such increase. METHODS:All psychiatric admissions aged 65 or older...

journal_title：International journal of geriatric psychiatry

authors： Lee ATC,Mo FYM,Lam LCW

更新日期：2020-09-06 00:00:00

abstract：OBJECTIVE:Our aim was to evaluate the effectiveness of a modified 8-week reminiscence therapy on the burden, positive experience, and life satisfaction of older spouse caregivers and the life satisfaction of stroke survivors. METHODS:We conducted a randomized controlled trial by using 75 older stroke couples recruited...

journal_title：International journal of geriatric psychiatry

authors： Mei Y,Lin B,Li Y,Ding C,Zhang Z

更新日期：2018-04-01 00:00:00