Neuropsychiatric disturbance in Alzheimer's disease clusters into three groups: the Cache County study.

abstract：OBJECTIVES:The Hospital Anxiety and Depression Scale (HADS) is a well-validated, self-report measure of both anxiety and depression. It is frequently used with people with dementia. However, its structural validity has never been examined in this population. The current study used confirmatory factor analysis (CFA) to ...

journal_title：International journal of geriatric psychiatry

authors： Stott J,Spector A,Orrell M,Scior K,Sweeney J,Charlesworth G

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:To describe sociodemographic data of patients with frontotemporal dementia (FTD), to compare the cognitive profile of patients with FTD with that of severity-matched patients with Alzheimer's disease using the CERAD neuropsychological battery (CERAD-NP), to investigate the frequency of behavioural disturbanc...

journal_title：International journal of geriatric psychiatry

authors： Diehl J,Kurz A

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:Sleep problems and depression are common symptoms in dementia with Lewy bodies (DLB), where patients typically experience subjectively poor sleep quality, fatigue and excessive daytime sleepiness. However, whilst sleep disturbances have been linked to depression, this relationship has not received much attent...

journal_title：International journal of geriatric psychiatry

authors： Elder GJ,Colloby SJ,Lett DJ,O'Brien JT,Anderson KN,Burn DJ,McKeith IG,Taylor JP

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Research has highlighted the influence of psychosocial factors on the wellbeing of carers of people with dementia. This study aimed to investigate the interrelationships between life events, depression and social support in carers of people with dementia. METHOD:Participants were 72 carers of people with de...

journal_title：International journal of geriatric psychiatry

authors： Waite A,Bebbington P,Skelton-Robinson M,Orrell M

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:Meta-analyses of antidepressant drug treatment trials have found that increasing age is associated with a less favourable outcome. Because the prevalence of geriatric characteristics, like disability, medical co-morbidity, malnutrition, cognitive (dys)function and frailty increase with age and are associated ...

journal_title：International journal of geriatric psychiatry

authors： Benraad CE,Kamerman-Celie F,van Munster BC,Oude Voshaar RC,Spijker J,Olde Rikkert MG

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The goal of the current study was to investigate psychological resilience in the older adults (>64 years) compared with that of the young ones (<26 years). METHODS:Questionnaire measures of depression, hopelessness, general health and resilience were administered to the participants. The resilience measure ...

journal_title：International journal of geriatric psychiatry

authors： Gooding PA,Hurst A,Johnson J,Tarrier N

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:This integrative review aimed to synthesize studies that investigated the effects of acupressure on sleep quality, depression, anxiety, and agitation in older people, and to describe the acupressure procedures and techniques applied in the included studies. METHODS:A literature search was conducted using el...

journal_title：International journal of geriatric psychiatry

authors： Hmwe NTT,Browne G,Mollart L,Allanson V,Chan SW

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was the development of the quality of life (QOL) questionnaire for dementia (QOL-D) in Japan. METHODS:We performed a questionnaire survey of QOL assessment in elderly patients with dementia in Japan, and developed QOL-D. RESULTS:The final version consists of only 31 items grouped ...

journal_title：International journal of geriatric psychiatry

authors： Terada S,Ishizu H,Fujisawa Y,Fujita D,Yokota O,Nakashima H,Haraguchi T,Ishihara T,Yamamoto S,Sasaki K,Nakashima Y,Kuroda S

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:In recent years, there has been a blossoming of studies examining cerebrospinal fluid (CSF) as a method of studying the pathophysiology of delirium. We systematically reviewed the literature for CSF studies in delirium and provide here a summary of the implications for our understanding of delirium pathophysi...

journal_title：International journal of geriatric psychiatry

authors： Hall RJ,Watne LO,Cunningham E,Zetterberg H,Shenkin SD,Wyller TB,MacLullich AMJ

更新日期：2018-11-01 00:00:00

abstract：INTRODUCTION:Little is known about the prevalence of impaired executive control function (ECF) in community dwelling elderly or minority populations. We have determined the prevalence of cognitive impairment and impaired ECF in a community dwelling Mexican American elderly population, and their associations with functi...

journal_title：International journal of geriatric psychiatry

authors： Royall DR,Espino DV,Polk MJ,Palmer RF,Markides KS

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVES:To compare directly, in the same patient cohort, the ease of use and tolerability of donepezil and galantamine in the treatment of Alzheimer's disease (AD), and investigate the effects of both treatments on cognition and activities of daily living (ADL). METHODS:Patients with mild to moderate AD from 14 Eur...

journal_title：International journal of geriatric psychiatry

authors： Jones RW,Soininen H,Hager K,Aarsland D,Passmore P,Murthy A,Zhang R,Bahra R

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:The objective of this pilot study was to gather preliminary evidence on suicidal ideation in family carers of people with dementia. METHODS:An online, cross-sectional survey was conducted with 120 family carers, the majority of whom were located in Australia and USA. The survey included measures of suicidali...

journal_title：International journal of geriatric psychiatry

authors： O'Dwyer ST,Moyle W,Zimmer-Gembeck M,De Leo D

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:This study explored whether patients with late-onset major depressive disorder showed higher carotid artery intima-medium thickness (IMT) and investigated the relationship between the IMT and white matter hyperintensities on magnetic resonance imaging (MRI) among patients. METHODS:Fourteen elderly patients ...

journal_title：International journal of geriatric psychiatry

authors： Chen CS,Chen CC,Kuo YT,Chiang IC,Ko CH,Lin HF

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:Staff ratings of quality of life (QOL) in dementia are often lower and more strongly related to the cognitive functioning of the person with dementia than self-ratings. However, cognition-related items in QOL measures and limited cognitive screening measures hamper a clear understanding of the relationship, 2...

journal_title：International journal of geriatric psychiatry

authors： Dewitte L,Vandenbulcke M,Dezutter J

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:The purpose of this study is to identify risk factors for nursing home placement of cognitively-impaired elderly, with special attention to the role of psychosocial factors such as the caregiver's preference for institutionalization and the quality of the dyadic relationship. METHODS:Partners, children and ...

journal_title：International journal of geriatric psychiatry

authors： Spruytte N,Van Audenhove C,Lammertyn F

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:An increasing evidence suggests hypertension (HTN) could be linked to cognitive impairment and incident Alzheimer's disease (AD). The precise mechanisms linking HTN and AD are not well-known. The aim of this study was to assess the putative association between HTN and AD. METHODS:We assessed in patients wit...

journal_title：International journal of geriatric psychiatry

authors： García-Alberca JM,Mendoza S,Gris E,Royo JL,Cruz-Gamero JM,García-Casares N

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Subjects with mild cognitive impairment (MCI) may revert to normal cognition (NC), but predictive factors are under study. We therefore sought to identify factors which could help in predicting reversion from MCI to NC. METHODS:Relevant studies were retrieved from PubMed, EMBASE, Cochrane Library, MEDLINE, W...

journal_title：International journal of geriatric psychiatry

authors： Xue H,Hou P,Li Y,Mao X,Wu L,Liu Y

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:This study examined the association between a history of heavy alcohol use and smoking, presence of the apolipoprotein-E epsilon 4 allele (APOE epsilon4), and age of disease onset in a community dwelling sample of 685 Alzheimer's disease (AD) patients spanning three ethnic groups. DESIGN:Cross-sectional stud...

journal_title：International journal of geriatric psychiatry

authors： Harwood DG,Kalechstein A,Barker WW,Strauman S,St George-Hyslop P,Iglesias C,Loewenstein D,Duara R

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:This study evaluated the impact of an eight-session training program for aged care staff in managing dementia-related challenging behaviours. Participation in the training program with an additional five-session peer support group was compared with both participation in training only and a wait-list control c...

journal_title：International journal of geriatric psychiatry

authors： Davison TE,McCabe MP,Visser S,Hudgson C,Buchanan G,George K

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:Currently available pharmacological treatments in Alzheimer's disease (AD) have been associated with modest benefits to cognition, but the impact on health-related quality of life (HRQoL) is less well established. Our aim was to determine if decline of specific cognitive functions commonly associated with AD ...

journal_title：International journal of geriatric psychiatry

authors： Bosboom PR,Almeida OP

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To derive norms for the Mini Mental State Examination (MMSE) based on age, gender and level of formal education among the elderly in Sri Lanka. METHOD:A validated Sinhalese version of the MMSE was administered to people aged 55 years and above residing in 14 randomly selected elders' homes. Effects of age, g...

journal_title：International journal of geriatric psychiatry

authors： De Silva R,Disanayaka S,De Zoysa N,Sanjeewanie N,Somaratne S,Foster J,Srikanth S,Kathriarachchi ST,Martins RM

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVES:The pattern of neural damage in dementia with Lewy Bodies (DLB) led us to hypothesize that patients with DLB would be particularly impaired on parallel ('pop-out') search tasks, relative to serial search tasks, and that this would serve to distinguish DLB from other forms of neurodegenerative disease, partic...

journal_title：International journal of geriatric psychiatry

authors： Cormack F,Gray A,Ballard C,Tovée MJ

更新日期：2004-08-01 00:00:00

abstract：:Studies reporting the quantity of benzodiazepines used are purely descriptive and cannot comment on the quality or appropriateness of prescribing benzodiazepines. An indicator to assess the appropriateness of prescribing benzodiazepines was developed from published literature. The applicability of the indicator was di...

journal_title：International journal of geriatric psychiatry

authors： Batty GM,Oborne CA,Swift CG,Jackson SH

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:Alzheimer's disease (AD) is prevalent among elderly people, who often have comorbid conditions, and may be prescribed multiple medications. Drug safety and tolerability is paramount in maximising efficacy and optimising patient and carer quality of life, as patients are vulnerable to adverse events (AEs) and/...

journal_title：International journal of geriatric psychiatry

authors： Jones RW

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:There is little information on the efficacy and side effects of antidepressant treatment in elderly patients with combined depression and cognitive impairment without dementia (DEP-MCI), and it is unclear if cognitive performance improves with antidepressant response in these patients. METHODS:In 39 elderly...

journal_title：International journal of geriatric psychiatry

authors： Devanand DP,Pelton GH,Marston K,Camacho Y,Roose SP,Stern Y,Sackeim HA

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Depression is a frequent problem in stroke patients but, all too often, the problem goes unrecognized. How depression-like symptoms in post-stroke depression (PSD) should be interpreted is still subject to debate. If PSD has a distinct symptom profile of depression accompanying other chronic vascular somatic...

journal_title：International journal of geriatric psychiatry

authors： Bour A,Rasquin S,Aben I,Strik J,Boreas A,Crijns H,Limburg M,Verhey F

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:This study identified factors in patients with diabetes associated with risk of developing dementia. RESEARCH DESIGN AND METHODS:This retrospective, longitudinal study used a national cohort of US Veterans with diabetes 65 years or older to examine incidence of dementia over 2 years. A multivariable Cox regr...

journal_title：International journal of geriatric psychiatry

authors： Parikh NM,Morgan RO,Kunik ME,Chen H,Aparasu RR,Yadav RK,Schulz PE,Johnson ML

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To determine whether older primary care patients with a Major Depressive Disorder (MDD) have lower heart rate variability (HRV) compared to non-depressed patients. HRV is a measure of cardiac autonomic functioning. METHOD:A cross-sectional comparison of 136 elderly persons with MDD and 136 non-depressed cont...

journal_title：International journal of geriatric psychiatry

authors： van der Kooy KG,van Hout HP,van Marwijk HW,de Haan M,Stehouwer CD,Beekman AT

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:To investigate whether primary care competency in early diagnosis of dementia might have changed during 1993 and 2001. METHOD:By means of a representative follow-up survey 122 out of 170 (71.8%) family physicians (FPs) in Lower Saxony, Germany, were randomly assigned to two written case samples presenting a ...

journal_title：International journal of geriatric psychiatry

authors： Maeck L,Haak S,Knoblauch A,Stoppe G

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:Although the evidence base for the use of antipsychotics in older people with schizophrenia is generally of low quality, it tends to support the use of atypical antipsychotics. Only limited information regarding longer term adherence to these apparently more effective drugs is available. The aim of this study...

journal_title：International journal of geriatric psychiatry

authors： Ritchie CW,Harrigan S,Mastwyk M,Macfarlane S,Cheesman N,Ames D

更新日期：2010-04-01 00:00:00