Structural correlates of apathy in Alzheimer's disease: a multimodal MRI study.

abstract：:Alzheimer's disease (AD) affects millions of people worldwide and the number of AD cases will increase with increased life expectancy. Today there is no cure for this devastating and always lethal disease and therefore it is of great interest for patients, relatives and societies to find new drugs that can hinder the ...

journal_title：International journal of geriatric psychiatry

authors： Ankarcrona M,Winblad B

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Despite a consensus on the need to expand and improve mental health care for older people, evidence on models of service development is limited. OBJECTIVE:Referring to two case studies, this paper considers how evaluation of service innovations can inform policy and practice. CONCLUSIONS:Evaluation should ...

journal_title：International journal of geriatric psychiatry

authors： McCrae N,Banerjee S

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the short-term tolerability of two titration schedules of sublingual asenapine in older patients with psychosis, not associated with organic brain disease, and to compare asenapine pharmacokinetics in older patients versus younger adults with schizophrenia. METHODS:Patien...

journal_title：International journal of geriatric psychiatry

authors： Dubovsky SL,Frobose C,Phiri P,de Greef R,Panagides J

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:To determine the efficacy and tolerability of citalopram when compared to other antidepressants for late-life depression (LLD). METHODS:We searched electronic databases and trial registries to identify randomized controlled trials comparing citalopram to other antidepressants for LLD. Study quality was asses...

journal_title：International journal of geriatric psychiatry

authors： Seitz DP,Gill SS,Conn DK

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Neuropsychiatric symptoms (NPS) are a common feature of Alzheimer's disease (AD), resulting in particular AD endophenotypes. The common AD genetic risk factor apolipoprotein E (APOE) has been suggested underlying these AD endophenotypes. METHODS:APOE genotyping, a comprehensive geriatric assessment (CGA), a...

journal_title：International journal of geriatric psychiatry

authors： D'Onofrio G,Panza F,Seripa D,Sancarlo D,Paris F,Cascavilla L,Urbano M,Gravina C,Fontana A,Solfrizzi V,Pellegrini F,Pilotto A

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Past research has demonstrated that there is a high level of depression among older people, particularly for those with cognitive impairment and those in residential care. The current study was designed to determine the prevalence of depression among older people in hostels with cognitive impairment using a ...

journal_title：International journal of geriatric psychiatry

authors： McCabe MP,Davison T,Mellor D,George K,Moore K,Ski C

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVES:Parental death during childhood, and offspring and spouse death during adulthood have individually been associated with faster cognitive decline and higher Alzheimer's disease (AD) risk in late life. However, the cumulative effect of childhood and adulthood family deaths on AD risk among different age cohort...

journal_title：International journal of geriatric psychiatry

authors： Norton MC,Fauth E,Clark CJ,Hatch D,Greene D,Pfister R,Tschanz JT,Smith KR

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:To summarise existing knowledge of outcomes of older hospital patients with cognitive impairment, including the type and frequency of outcomes reported, and the additional risk experienced by this patient group. METHODS:Integrative literature review. Health care literature databases, reports, and policy doc...

journal_title：International journal of geriatric psychiatry

authors： Fogg C,Griffiths P,Meredith P,Bridges J

更新日期：2018-06-26 00:00:00

abstract：OBJECTIVE:The Lewy body dementias (LBD, dementia with Lewy bodies and Parkinson's disease dementia) are the second most common cause of neurodegenerative dementia but remain under-recognised, with long delays from initial assessment to diagnosis. Whilst validated instruments have been developed for key symptoms, there ...

journal_title：International journal of geriatric psychiatry

authors： Thomas AJ,Taylor JP,McKeith I,Bamford C,Burn D,Allan L,O'Brien J

更新日期：2017-12-01 00:00:00

abstract：INTRODUCTION:Short-form versions of the Montreal Cognitive Assessment (SF-MoCA) are increasingly used to screen for dementia in research and practice. We sought to collate evidence on the accuracy of SF-MoCAs and to externally validate these assessment tools. METHODS:We performed systematic literature searching across...

journal_title：International journal of geriatric psychiatry

authors： McDicken JA,Elliott E,Blayney G,Makin S,Ali M,Larner AJ,Quinn TJ,VISTA-Cognition Collaborators.

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:Subjects with mild cognitive impairment (MCI) may revert to normal cognition (NC), but predictive factors are under study. We therefore sought to identify factors which could help in predicting reversion from MCI to NC. METHODS:Relevant studies were retrieved from PubMed, EMBASE, Cochrane Library, MEDLINE, W...

journal_title：International journal of geriatric psychiatry

authors： Xue H,Hou P,Li Y,Mao X,Wu L,Liu Y

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:We estimated the cost effectiveness of different cognitive screening tests for use by General Practitioners (GPs) to detect cognitive impairment in England. METHODS:A patient-level cost-effectiveness model was developed using a simulated cohort that represents the elderly population in England (65 years a...

journal_title：International journal of geriatric psychiatry

authors： Tong T,Thokala P,McMillan B,Ghosh R,Brazier J

更新日期：2017-12-01 00:00:00

abstract：:A major tenet of gerontological practice and policy has been that community-based services relieve stress on family caregivers and delay or prevent institutionalization of frail elders. Evidence for benefits of community-based services is examined from four perspectives: (1) relief for family caregivers; (2) benefits ...

journal_title：International journal of geriatric psychiatry

authors： Zarit SH,Gaugler JE,Jarrott SE

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between regular physical activity and the risk of incident dementia in older Japanese adults. METHODS:This was a retrospective cohort study performed in Okayama City, Japan. Overall, 51 477 older Japanese adults were followed from 2008 to 2014. A health checkup questionnaire was u...

journal_title：International journal of geriatric psychiatry

authors： Liu Y,Mitsuhashi T,Yamakawa M,Sasai M,Tsuda T,Doi H,Hamada J

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To investigate associations between vision impairment (VI), vision correction (VC) and depressive symptoms among middle-aged and older Chinese. METHODS:22 203 participants aged ≥45 years from China Health and Retirement Longitudinal Study 2011 to 2015 were divided into four self-reported VI categories: no VI...

journal_title：International journal of geriatric psychiatry

authors： Zhang Q,Cao GY,Yao SS,Wang C,Chen ZS,Hu YH,Xu B

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:The objective of this study is to determine whether resilience is associated with depressive symptoms in geriatric populations. METHOD:A systematic review and meta-analysis were performed (up to March 2015) following the Preferred Reporting Items for Systematic Reviews and Meta-analysis recommendations on th...

journal_title：International journal of geriatric psychiatry

authors： Wermelinger Ávila MP,Lucchetti AL,Lucchetti G

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to assess lay persons' perceptions about the competence of a person with AD and its relationship to social distance. METHODS:Face-to-face interviews were conducted with a total of 206 Jewish Israeli adults (mean age = 59.7) using an experimental vignette methodology, varying ...

journal_title：International journal of geriatric psychiatry

authors： Werner P

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Apathy and depression are the most common neuropsychiatric features in Alzheimer's disease (AD). The clinical and functional specific correlates of these syndromes are not well known independently from cognitive deficits and other behavioral disturbances. MATERIAL AND METHODS:Six hundred and eighty-six pati...

journal_title：International journal of geriatric psychiatry

authors： Benoit M,Andrieu S,Lechowski L,Gillette-Guyonnet S,Robert PH,Vellas B,REAL-FR group.

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVES:Assessment of functional ability in people with early-stage dementia (PwD) is an important area of study because it forms part of the diagnostic process and may help in monitoring disease progression. Most researchers and clinicians rely on informant ratings rather than observing actual functional performanc...

journal_title：International journal of geriatric psychiatry

authors： Martyr A,Clare L

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:Previous studies have identified several subgroups (ie, latent trajectories) with distinct disease progression among people with dementia. However, the methods and results were not always consistent. This study aims to perform a coordinated analysis of latent trajectories of cognitive and functional progress...

journal_title：International journal of geriatric psychiatry

authors： Wang Y,Haaksma ML,Ramakers IHGB,Verhey FRJ,van de Flier WM,Scheltens P,van Maurik I,Olde Rikkert MGM,Leoutsakos JS,Melis RJF

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:To assess the cost effectiveness of cholinesterase inhibitor (ChEI) treatment in patients with Alzheimer's disease (AD) and Dementia with Lewy bodies (DLB). METHOD:We used 4-month open label follow-up data from routine memory clinic patients. There were 852 patients with AD and 112 with DLB. We applied three...

journal_title：International journal of geriatric psychiatry

authors： Gustavsson A,Van Der Putt R,Jönsson L,McShane R

更新日期：2009-10-01 00:00:00

abstract：UNLABELLED:Data on the prevalence of and risk factors for suicide ideation among older people in developing countries is lacking. OBJECTIVE:This study aimed to estimate if dementia and other mental disorders are associated with suicide ideation among the older people controlling for demographic and other suspected ris...

journal_title：International journal of geriatric psychiatry

authors： Borges G,Acosta I,Sosa AL

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:There is limited literature around peer research in dementia. This study aims to identify the benefits, the risks and the practical challenges and to develop a model of good practice in peer research with people with dementia. METHODS:We searched on PsycInfo, PubMed and Google Scholar for empirical investig...

journal_title：International journal of geriatric psychiatry

authors： Di Lorito C,Birt L,Poland F,Csipke E,Gove D,Diaz-Ponce A,Orrell M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:to investigate the suicide phenomenon among the elderly (people aged 65 and over) in the Italian provinces of Novara and Verbania, in the time span between January 1990 and December 2000, in order to evaluate if the characteristics of the suicide behaviour correlate to the place of living with particular att...

journal_title：International journal of geriatric psychiatry

authors： Zeppegno P,Manzetti E,Valsesia R,Siliquini R,Ammirata G,De Donatis O,Usai C,Torre E

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Current outcome measures for Alzheimer's disease (AD) drugs have been criticized as insufficiently patient-centred. One commonly unmeasured goal of patients and caregivers is verbal repetition. OBJECTIVES:We examined how often reducing repetition (of questions, statements or stories) was set as treatment go...

journal_title：International journal of geriatric psychiatry

authors： Asp E,Cloutier F,Fay S,Cook C,Robertson ML,Fisk J,Dei DW,Rockwood K

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to examine the unidimensionality, item fit, redundancy and differential item functioning (DIF) of the 15-item version of the Geriatric Depression Scale (GDS) in a community sample of 300 Hong Kong Chinese patients with pneumoconiosis. METHODS:Participants were randomly selected...

journal_title：International journal of geriatric psychiatry

authors： Tang WK,Wong E,Chiu HF,Lum CM,Ungvari GS

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVES:Delirium is associated with poor outcomes. Previous research in delirium and mortality gave rather inconclusive results. This study aims to find out the rates of mortality at 1 year and the factors associated with it in a cohort of hospitalized older patients. METHOD:Prospective, observational, longitudinal...

journal_title：International journal of geriatric psychiatry

authors： Muresan ML,Adamis D,Murray O,O'Mahony E,McCarthy G

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Sleep problems and depression are common symptoms in dementia with Lewy bodies (DLB), where patients typically experience subjectively poor sleep quality, fatigue and excessive daytime sleepiness. However, whilst sleep disturbances have been linked to depression, this relationship has not received much attent...

journal_title：International journal of geriatric psychiatry

authors： Elder GJ,Colloby SJ,Lett DJ,O'Brien JT,Anderson KN,Burn DJ,McKeith IG,Taylor JP

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:The study objective is to evaluate the use of qEEG data for the cross-sectional differentiation of mild cognitive impairment (MCI) from mild Alzheimer's disease (AD) and in the longitudinal prediction of cognitive decline in MCI. METHODS:Eighty-eight subjects with MCI and 42 subjects with mild probable AD we...

journal_title：International journal of geriatric psychiatry

authors： Luckhaus C,Grass-Kapanke B,Blaeser I,Ihl R,Supprian T,Winterer G,Zielasek J,Brinkmeyer J

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Depression frequently co-occurs with cognitive decline, but the nature of this association is unclear. We examined relations of late-life depressive symptom patterns to subsequent domain-specific cognitive changes. METHODS:Depressive symptoms were measured at up to 3 timepoints among 11,675 Nurses' Health S...

journal_title：International journal of geriatric psychiatry

authors： Gillis JC,Chang SC,Devore EE,Rosner BA,Grodstein F,Okereke OI

更新日期：2017-12-01 00:00:00