Abstract:
OBJECTIVE:To evaluate the association between regular physical activity and the risk of incident dementia in older Japanese adults. METHODS:This was a retrospective cohort study performed in Okayama City, Japan. Overall, 51 477 older Japanese adults were followed from 2008 to 2014. A health checkup questionnaire was used to assess regular physical activity. The Dementia Scale of long-term care insurance was used as a measure of incident dementia. Cox proportional hazard models were used to calculate adjusted hazard ratios, with their 95% confidence intervals, for the incidence of dementia across the categories of physical activity. RESULTS:During a 7-year follow-up, 13 816 subjects were considered as having incident dementia. Compared with participants who performed physical activity less than or equal to one time per week, the multivariate adjusted hazard ratio values (95% confidence intervals) for participants who performed physical activity greater than or equal to two times per week but not every day and those who performed physical activity every day were 0.79 (0.75-0.84) and 0.94 (0.89-0.98), respectively. The interaction of physical activity and sex was statistically significant (P < .01). In subgroup analysis, the multivariate-adjusted hazard ratio values (95% confidence intervals) remained low, at 0.76 (0.70-0.84) in males and 0.81 (0.76-0.87) in females who performed physical activity greater than or equal to two times per week but not every day; they were 0.82 (0.76-0.89) in males and 1.01 (0.95-1.07) in females who performed physical activity every day. CONCLUSIONS:Regular physical activity could reduce the risk of incident dementia in older Japanese adults, except females who performed physical activity every day.
journal_name
Int J Geriatr Psychiatryjournal_title
International journal of geriatric psychiatryauthors
Liu Y,Mitsuhashi T,Yamakawa M,Sasai M,Tsuda T,Doi H,Hamada Jdoi
10.1002/gps.5135subject
Has Abstractpub_date
2019-10-01 00:00:00pages
1429-1437issue
10eissn
0885-6230issn
1099-1166journal_volume
34pub_type
杂志文章abstract:BACKGROUND:Morbidity among elderly people has an important influence on their psychological well-being. Evaluation of the morbidity profile and its determinants, which have implications for management of medical problems of elderly people, are scarce in developing countries. Even the physicians' detection rate of menta...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.1793
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVE:Modifiable risk factors for dementia were recently identified and compiled in a systematic review. The 'Lifestyle for Brain Health' (LIBRA) score, reflecting someone's potential for dementia prevention, was studied in a large longitudinal population-based sample with respect to predicting cognitive change ove...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.4700
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:The Lewy body dementias (LBD, dementia with Lewy bodies and Parkinson's disease dementia) are the second most common cause of neurodegenerative dementia but remain under-recognised, with long delays from initial assessment to diagnosis. Whilst validated instruments have been developed for key symptoms, there ...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.4609
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:To identify carer and patient characteristics associated with various aspects of burden of care. METHOD:The burden on 196 carers, each caring for one patient with dementia, was rated by means of the Relative Stress Scale (RSS). Patients were assessed with the Mini Mental State Examination (MMSE), the Disabil...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.1654
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVES:The present study assessed whether caregiving contextual factors moderated outcomes of a caregiver intervention. METHODS:Extant data from the Resources for Enhancing Alzheimer's Caregiver Health (REACH) II study, a randomized-control trial of a multi-component, multi-site intervention for dementia caregiver...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/gps.4019
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVES:To investigate the structure and measurement properties of the Psychogeriatric Assessment Scales (PAS) in a community sample, to study the performance of French and German translations of the PAS, and to determine the power of PAS scales to discriminate dementia and depression diagnosed to DSM-IV criteria. D...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.442
更新日期:2001-09-01 00:00:00
abstract:OBJECTIVES:The number of older adults with severe mental health problems such as schizophrenia is likely to double in the next 20 years. The needs of this patient group change across the life course, but difficulties with social functioning persist into older age. Poorer social functioning is associated with poorer out...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.5264
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVES:The aims of this study were to identify factors of significance in the development of acute confusional state (ACS) and the differences between patients who developed ACS and those who did not. METHOD AND RESULTS:Assessment, observations and interviews with 505 patients admitted to an orthopaedic clinic rev...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/1099-1166(200101)16:1<7::aid-gps261>3.0.co
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVES:This study investigated cognitive impairment in late-life depression in a follow-up design. The main objective was to assess the most important cognitive domains implicated in late-life depression, in patients who underwent pharmacological treatment, in the acute phase and twelve months after. METHODS:Neuro...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.895
更新日期:2003-07-01 00:00:00
abstract::Alzheimer's disease (AD) affects millions of people worldwide and the number of AD cases will increase with increased life expectancy. Today there is no cure for this devastating and always lethal disease and therefore it is of great interest for patients, relatives and societies to find new drugs that can hinder the ...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章,评审
doi:10.1002/gps.1260
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:Nowadays, there is an increasing interest in the heritable aspects of Alzheimer's Disease (AD). The ethical implications of this kind of research are also attracting attention. However, relatively few open-ended qualitative studies have been carried out to study these aspects. OBJECTIVE:To explore and analy...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章,多中心研究,评审
doi:10.1002/gps.1825
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Beneficial effects of repetitive transcranial magnetic stimulation (rTMS) were demonstrated by many controlled studies in major depression. Moreover, this promising and non invasive therapeutic tool seems to be better tolerated than electroconvulsive therapy.Vascular depression is a subtype of late-life depr...
journal_title:International journal of geriatric psychiatry
pub_type: 临床试验,杂志文章
doi:10.1002/gps.1172
更新日期:2004-09-01 00:00:00
abstract:UNLABELLED:Data on the prevalence of and risk factors for suicide ideation among older people in developing countries is lacking. OBJECTIVE:This study aimed to estimate if dementia and other mental disorders are associated with suicide ideation among the older people controlling for demographic and other suspected ris...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.4134
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:There is much variation in the services provided for older people with mental health problems. In England, the National Service Framework for Older People (NSFOP) sought to address these inconsistencies and improve care. This study describes the situation three years after its publication. METHODS:A postal ...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.1662
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:The management of Behavioural and Psychological Symptoms of Dementia (BPSD) has been the subject of considerable debate over the last few years in view of the poor evidence base for pharmacological agents and concerns about their safety. OBJECTIVES:This study sought to obtain expert opinion on the managemen...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.2200
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Timely recognition and diagnosis of dementia is the pre-condition for improving dementia care, but diagnosis often occurs late in the disease process. OBJECTIVE:To compare facilitators and obstacles to the timely recognition of dementia across eight European Union states, in order to implement established p...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章,多中心研究
doi:10.1002/gps.1302
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:Cognitive screening instruments are either too long for routine clinical use or not sensitive to distinguish mild cognitive impairment (MCI) from normal cognition (NC) or dementia. OBJECTIVE:To evaluate the sensitivity and specificity of the AB Cognitive Screen (ABCS) and its subtests with a view to improvi...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.1659
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:There is a paucity of cross-cultural studies of behavioural and psychological symptoms of dementia (BPSD). METHOD:BPSD were examined in a consecutive series of Indian sub-continent origin and white indigenous elders admitted to a dementia day hospital using the BEHAVE-AD. The correlates of individual BPSD i...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.1245
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVES:Since plasma protein binding of tricyclic antidepressants may be relevant to treatment effects and can be influenced by age-associated factors, we examined both plasma ultrafiltrate and total concentrations of nortriptyline (NT) in patients and compared these to age. We hypothesized negative associations wit...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/1099-1166(200011)15:11<1009::aid-gps228>3.
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:To examine the effects of risperidone and olanzapine on cognitive functioning in elderly patients with schizophrenia or schizoaffective disorder. METHOD:One hundred seventy-six elderly inpatients and outpatients with schizophrenia or schizoaffective disorder were enrolled in this multicenter, double-blind tr...
journal_title:International journal of geriatric psychiatry
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1002/gps.929
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:Sleep problems and depression are common symptoms in dementia with Lewy bodies (DLB), where patients typically experience subjectively poor sleep quality, fatigue and excessive daytime sleepiness. However, whilst sleep disturbances have been linked to depression, this relationship has not received much attent...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.4389
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVE:To systematically review and analyze the efficacy and tolerability of different antidepressant pharmacologic treatments for depressive symptoms in Parkinson's disease (PD) METHODS: We searched PubMed, EMBASE, Cochrane database (CENTRAL), clinicaltrials.gov, and bibliographies for randomized controlled trials ...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章,meta分析
doi:10.1002/gps.4834
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:In an earlier report, response inhibition predict antidepressant non-response in late-life depression (Sneed et al., 2007). The purpose of this study was to ascertain whether this effect is specific to response inhibition or whether impairment in other cognitive domains also predicts non-response. METHOD:Old...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/gps.1889
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVE:To examine whether intensive care unit (ICU) admission is independently associated with increased risk of major depression in patients with diabetes. METHODS:This prospective cohort study included 3596 patients with diabetes enrolled in the Pathways Epidemiologic Follow-Up Study, of whom 193 had at least one...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.2684
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:We evaluated the feasibility and acceptability of a tailored evidence-based intervention, consisting of a leaflet and a letter, to encourage timely help-seeking for dementia in Black elders. METHODS:Participating GP surgeries were randomised to send either the intervention or a control leaflet about ageing w...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1002/gps.4891
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:To investigate whether primary care competency in early diagnosis of dementia might have changed during 1993 and 2001. METHOD:By means of a representative follow-up survey 122 out of 170 (71.8%) family physicians (FPs) in Lower Saxony, Germany, were randomly assigned to two written case samples presenting a ...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/gps.1646
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:Minor stroke is characterized by mild neurological functional impairment and relatively good outcome. Little is known about the association between post-stroke depression (PSD) and outcomes of minor stroke. The aim of this study was to investigate the association between PSD and disability and quality of life...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.4353
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Agitated behaviours among persons with dementia are distressing to both patients and their caregivers. As pharmacological interventions may be limited by their potentially adverse effects, the use of complementary therapies for treatment of agitation has become more popular and aromatherapy is the fastest gr...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1002/gps.1688
更新日期:2007-05-01 00:00:00
abstract::Divalproex is now commonly used to treat bipolar disorder in older patients. However, it has yet to be systematically studied in this population. This report describes six older bipolar patients treated with divalproex. Of the six, five showed some improvement with divalproex alone or in combination with other agents....
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/(sici)1099-1166(199906)14:6<494::aid-gps96
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVE:Subjects with mild cognitive impairment (MCI) may revert to normal cognition (NC), but predictive factors are under study. We therefore sought to identify factors which could help in predicting reversion from MCI to NC. METHODS:Relevant studies were retrieved from PubMed, EMBASE, Cochrane Library, MEDLINE, W...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章,meta分析,评审
doi:10.1002/gps.5159
更新日期:2019-10-01 00:00:00