Abstract：
OBJECTIVE:We evaluated the feasibility and acceptability of a tailored evidence-based intervention, consisting of a leaflet and a letter, to encourage timely help-seeking for dementia in Black elders. METHODS:Participating GP surgeries were randomised to send either the intervention or a control leaflet about ageing well to Black patients aged ≥50 years old without known dementia. We interviewed patients 2 weeks later about the intervention's acceptability using closed and open-ended questions, and they completed a Theory-of-Planned-behaviour questionnaire about what they would do if they developed memory problems, which they also completed 4 months later. RESULTS:Five of 26 surgeries approached agreed to invite patients. Sixty-five patients responded, of whom 61 (93.8%) agreed to participate. At 2 weeks, we consented and interviewed 47/61 (77%), of whom 24 received the intervention, and at 4 months we followed up 43/47 (91.5%). At 2 weeks, 44/47 (93.6%) found either intervention acceptable to receive by post, including 23/24 of the intervention. Nineteen of 24 (79.2%) reported reading the intervention leaflet compared with 13/23 (56.5%) controls. The intervention leaflet made 16/24 (66.7%) think about visiting their doctor for memory problems and led 4 to help-seeking behaviour. We calculated that 191 patients and 24 surgeries are required for an efficacy trial. CONCLUSIONS:Given the intervention is acceptable, inexpensive, and unlikely to cause harm, we judge it appropriate to disseminate it without a full-scale trial. Recruitment attainment, retention, and projected sample size calculation indicated feasibility for a larger trial.
journal_name
Int J Geriatr Psychiatryjournal_title
International journal of geriatric psychiatryauthors
Roche M,Mukadam N,Adelman S,Livingston Gdoi
10.1002/gps.4891subject
Has Abstractpub_date
2018-08-01 00:00:00pages
1048-1056issue
8eissn
0885-6230issn
1099-1166journal_volume
33pub_type
杂志文章,随机对照试验abstract：OBJECTIVES:Depression in late life has been associated with difficulties in cognitive processing, particularly in the domains of executive function, processing speed and memory, and increases the risk of developing dementia suggesting a neurodegenerative phenotype. Mitochondrial dysfunction is frequently an early event...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4439
更新日期：2016-11-01 00:00:00
abstract：BACKGROUND:Despite the fact that the current definitions of dementia in the DSM-IV and ICD-10 require functional deterioration for the diagnosis of dementia, it is not necessary a formal evaluation of functional capacity. OBJECTIVES:To examine the efficiency of functional assessment as a method of screening dementia i...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章,meta分析,评审
doi：10.1002/gps.1747
更新日期：2007-09-01 00:00:00
abstract：OBJECTIVES:To identify factors which may contribute to prolonged length of stay in an elderly psychiatric inpatient setting. DESIGN:Retrospective case note study. METHODS:A list of all patients over the age of 65 discharged from a private psychiatric hospital over a three-year period excluding those with a length of ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.463
更新日期：2001-10-01 00:00:00
abstract：OBJECTIVES:Social network (SN) has been known to impact on cognitive function in late life. However, knowledge regarding the link between SN of various types and cognitive decline (CD) is limited. This study's aim was to investigate which types of SN are associated with reduced risk of CD 2 years later among community-...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.5200
更新日期：2019-12-01 00:00:00
abstract：:Reduced N-acetyl aspartate (NAA) and increased myo-inositol (MI) levels have been reported in patients with dementia of Alzheimer type (DAT) in comparison with controls. We wished to assess the validity of these findings and to evaluate possible correlations of metabolite proportions with cognitive dysfunction in DAT....
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/(sici)1099-1166(199703)12:3<349::aid-gps50
更新日期：1997-03-01 00:00:00
abstract：OBJECTIVES:The pattern of neural damage in dementia with Lewy Bodies (DLB) led us to hypothesize that patients with DLB would be particularly impaired on parallel ('pop-out') search tasks, relative to serial search tasks, and that this would serve to distinguish DLB from other forms of neurodegenerative disease, partic...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1159
更新日期：2004-08-01 00:00:00
abstract：OBJECTIVE:To examine the effectiveness of dementia programmes and report factors related to programme outcomes. To describe the characteristics which placed hostel residents at risk for nursing home placement and to measure changes in dependencies and impairments over 2 years. DESIGN:Longitudinal, quasi-experimental u...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/(sici)1099-1166(199702)12:2<173::aid-gps59
更新日期：1997-02-01 00:00:00
abstract：:Less than one-tenth of all population-based research into dementia is directed towards the two-thirds or more of cases living in developing parts of the world. The 10/66 Dementia Research Group has been formed to redress this imbalance, encouraging active research collaboration between centres in different developing ...
journal_title：International journal of geriatric psychiatry
pub_type： 共识发展会议,杂志文章,评审
doi：10.1002/(sici)1099-1166(200001)15:1<14::aid-gps70>
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVE:We investigated cognitive dysfunction in patients with Alzheimer's disease (AD) and amnestic mild cognitive impairment (aMCI) who present hemispheric asymmetries of cerebral metabolic rate of glucose (CMRglc) decrease on (18) F-fluorodeoxyglucose positron emission tomography. METHODS:Based on the hemispheric...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4287
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVES:To evaluate the association between the degree of integration in community mental health teams (CMHTs) and: (i) the costs of service provision; (ii) rates of mental health inpatient and care home admission. METHODS:An observational study of service use and admissions to institutional care was undertaken for...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4424
更新日期：2016-11-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to evaluate mortality and causes of death in older patients with schizophrenia in comparison with the general population. The mortality of patients experiencing relapse was also compared with those in remission. METHODS:The study sample consists of patients (n = 9461) over 65 years ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.2833
更新日期：2012-11-01 00:00:00
abstract：INTRODUCTION:Short-form versions of the Montreal Cognitive Assessment (SF-MoCA) are increasingly used to screen for dementia in research and practice. We sought to collate evidence on the accuracy of SF-MoCAs and to externally validate these assessment tools. METHODS:We performed systematic literature searching across...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.5162
更新日期：2019-10-01 00:00:00
abstract：OBJECTIVE:To determine whether older primary care patients with a Major Depressive Disorder (MDD) have lower heart rate variability (HRV) compared to non-depressed patients. HRV is a measure of cardiac autonomic functioning. METHOD:A cross-sectional comparison of 136 elderly persons with MDD and 136 non-depressed cont...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1439
更新日期：2006-02-01 00:00:00
abstract：OBJECTIVES:To compare directly, in the same patient cohort, the ease of use and tolerability of donepezil and galantamine in the treatment of Alzheimer's disease (AD), and investigate the effects of both treatments on cognition and activities of daily living (ADL). METHODS:Patients with mild to moderate AD from 14 Eur...
journal_title：International journal of geriatric psychiatry
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1002/gps.1038
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVE:To find a blood biomarker and disease-related peptides in Alzheimer's disease (AD), we comprehensively detected serum peptides. METHODS:Ion intensity of serum peptides from 62 AD patients and 82 control subjects was measured by mass spectrometry. RESULTS:A total of 157 peptides were detected from 30 AD pati...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4047
更新日期：2014-08-01 00:00:00
abstract：:Wolf-Klein and colleagues' clock drawing test (CDT) performance was compared with Pfeiffer's Short Portable Mental Status Questionnaire (Pfeiffer) scores in 145 outpatient geropsychiatry patients. Although normal CDT results were almost always associated with normal Pfeiffer scores, 21% of Pfeiffer normal individuals ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/(sici)1099-1166(199705)12:5<526::aid-gps53
更新日期：1997-05-01 00:00:00
abstract：BACKGROUND:Depression frequently co-occurs with cognitive decline, but the nature of this association is unclear. We examined relations of late-life depressive symptom patterns to subsequent domain-specific cognitive changes. METHODS:Depressive symptoms were measured at up to 3 timepoints among 11,675 Nurses' Health S...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4618
更新日期：2017-12-01 00:00:00
abstract：OBJECTIVE:The aim of the present study was to assess lay persons' perceptions about the competence of a person with AD and its relationship to social distance. METHODS:Face-to-face interviews were conducted with a total of 206 Jewish Israeli adults (mean age = 59.7) using an experimental vignette methodology, varying ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1546
更新日期：2006-07-01 00:00:00
abstract：OBJECTIVE:Sleep problems and depression are common symptoms in dementia with Lewy bodies (DLB), where patients typically experience subjectively poor sleep quality, fatigue and excessive daytime sleepiness. However, whilst sleep disturbances have been linked to depression, this relationship has not received much attent...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4389
更新日期：2016-07-01 00:00:00
abstract：OBJECTIVES:Research indicates increasing trends among older adults toward heavy and abusive drinking, often associated with depressive symptoms. Possible exceptions are residents of planned retirement communities, whose drinking may be associated with social activities. To better understand these relationships, this st...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4359
更新日期：2016-05-01 00:00:00
abstract：OBJECTIVE:The aim of this study is to examine the hypotheses stating the importance of amyloid or of its oligomers in the pathogenesis of Alzheimer's disease (AD). METHODS:Published studies were examined. RESULTS:The importance of amyloid in the pathogenesis of AD is well established, yet accepting it as the main cau...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章,评审
doi：10.1002/gps.4730
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Scales measuring cognitive and executive functions are integral to the assessment and management of patients with suspected cognitive impairment. Some of the most commonly used cognitive tests are now subject to copyright restrictions. Furthermore, no existing scale assesses both executive and cognitive abil...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.5454
更新日期：2020-10-29 00:00:00
abstract：BACKGROUND:This study is part of the Research to Assess Policies and Strategies for Dementia in the Young project. Information about specific needs in young onset dementia (YOD) will provide the basis for the development of an e-health intervention to assist caregivers in coping with YOD in several European countries. ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4749
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVE:To evaluate the prevalence, clinical features, and comorbidities of restless legs syndrome (RLS) among psychogeriatric patients in an out-patient clinical setting. METHODS:Cross-sectional study of a sample of 100 non-demented psychogeriatric outpatients that were assessed for the presence of RLS using the Re...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.2674
更新日期：2011-12-01 00:00:00
abstract：OBJECTIVES:Dementia is the most common neurological disease in older adults; headaches, including migraines, are the most common neurological disorder across all ages. The objective of this study was to explore the relationship between migraines and dementia, including Alzheimer's disease (AD) and vascular dementia (Va...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.5180
更新日期：2019-11-01 00:00:00
abstract：OBJECTIVE:To establish the factor structure, reliability and validity of a brief CESD scale among Community dwelling older adults in Singapore. METHOD:Data were derived from interviews conducted among 1,013 randomly selected non-institutionalized older adults aged 65 years and above in Singapore. First, Confirmatory F...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1944
更新日期：2008-06-01 00:00:00
abstract：AIM:To assess the effectiveness of reminiscence and life review on late-life depression across different target groups and treatment modalities. METHOD:Twenty controlled outcome studies were retrieved from Psychlit, Medline and Dissertation Abstracts. For each study a standardised effect size, d, was calculated and a ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章,meta分析
doi：10.1002/gps.1018
更新日期：2003-12-01 00:00:00
abstract：BACKGROUND:Deliberate self harm (DSH) in later life is under researched and is believed to be related to both mental illness and suicide. AIMS:The aim of the study was to examine deliberate self-harm (DSH) in older people presenting to acute hospital services over three years. METHOD:This was a retrospective observat...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1404
更新日期：2005-11-01 00:00:00
abstract：OBJECTIVES:To investigate the effect of cobalamin/folate supplementation on cognitive function in elderly patients with dementia. METHOD:The cobalamin/folate status of the patients was evaluated by measuring plasma homocysteine, serum methylmalonic acid, serum cobalamin and blood folate. Thirty-three patients were stu...
journal_title：International journal of geriatric psychiatry
pub_type： 临床试验,杂志文章
doi：10.1002/gps.388
更新日期：2001-06-01 00:00:00
abstract：OBJECTIVE:Rivastigmine, a dual cholinesterase inhibitor (ChEI), is widely approved for the symptomatic treatment of both mild-to-moderate Alzheimer's disease (AD) and Parkinson's disease dementia. Orally administered ChEIs may be associated with gastrointestinal (GI) side effects and add-on therapy with memantine, an N...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章,多中心研究
doi：10.1002/gps.2355
更新日期：2010-04-01 00:00:00
