Cholestasis associated with total parenteral nutrition.

abstract：OBJECTIVES:Differentiating ulcerative colitis (UC) and Crohn disease (CD) can be clinically challenging, especially in children. Granulomatous inflammation has traditionally been attributed to CD. Crypt-associated giant cells and granulomas, however, have been observed in colonic biopsies of patients with UC. This phen...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Queliza K,Ihekweazu FD,Schady D,Jensen C,Kellermayer R

更新日期：2018-04-01 00:00:00

abstract：:Lactose synthesized in the mammary gland can pass into the bloodstream by either a paracellular or transcellular pathway. In nonpregnant, nonlactating women, the concentration of lactose in the blood plasma was 1.5 +/- 0.1 microM (mean +/- SEM) in 9 women and undetectable in another 11 women. During pregnancy, this co...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Arthur PG,Kent JC,Potter JM,Hartmann PE

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVES:δ-Bilirubin (Bδ) forms when bilirubin conjugates covalently bind to albumin by way of nonenzymatic transesterification in patients with cholestasis. Infants with cholestasis with biliary atresia form Bδ. The aim of the present study was to investigate the factors determining serum Bδ concentrations in infant...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ye W,Rosenthal P,Magee JC,Whitington PF,Childhood Liver Disease Research and Education Network.

更新日期：2015-05-01 00:00:00

abstract：:IgA anti-gliadin antibodies (AGA), interleukin-2 (IL-2), and soluble interleukin-2 receptor (sIL-2R) were analyzed in serum from 28 children with symptoms of celiac disease and villous atrophy in at least their first small bowel biopsy. We also assayed IL-2 and sIL-2R in 45 healthy children and IgA anti-gliadin antibo...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Penedo-Pita M,Peteiro-Cartelle J

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:The role of milk polyamines in the development of the gastrointestinal tract of human infants is presently unknown. Polyamine concentrations are higher in human milk than in infant formulas. The aim of the present study was to gather data on luminal polyamines by measuring gastric fluid and fecal polyamine c...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Forget PP,Degraeuwe PL,Smeets C,Deutz NE

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:Pediatric Rome III criteria of functional dyspepsia (FD) has eliminated the mandatory use of upper endoscopy and recommended a symptom-based approach. In the absence of alarm symptoms, FD can be positively diagnosed in children having normal physical findings without exclusionary investigations. We aimed to i...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Tam YH,Chan KW,To KF,Cheung ST,Mou JW,Pang KK,Wong YS,Sihoe JD,Lee KH

更新日期：2011-04-01 00:00:00

abstract：:Both storage of breast milk for 3 days at 4 degrees C and the addition of breast milk fortifier containing lipid improved the delivery of lipids during continuous pump infusion. The percentage of the original lipid delivered after 8 h of pumping was 9, 25, 58, and 66% from the freshly collected milk, stored milk, fres...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Lavine M,Clark RM

更新日期：1989-05-01 00:00:00

abstract：OBJECTIVES:Inflammatory bowel disease (IBD) is a chronic lifelong condition and is related to poor quality of life (QoL). The aim of this study was to evaluate the QoL of Asian pediatric patients with IBD and to determine the clinical factors that can influence QoL. METHODS:Children and adolescents aged 9 to 18 years ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kim S,Park S,Kang Y,Kim JE,Kang B,Choe BH,Lee YJ,Park JH,Yang HR,Lee SH,Kim KM,Ryoo E,Tchah H,Shim JO,Koh H

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of propofol and meperidine plus midazolam for sedation during esophagogastroduodenoscopy (EGD) in children. METHODS:Data were collected prospectively and retrospectively from neurologically intact children (0.2-17.7 years of age) who underwent ambulatory diagnostic EGD dur...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Khoshoo V,Thoppil D,Landry L,Brown S,Ross G

更新日期：2003-08-01 00:00:00

abstract：:Chronic constipation is one of the most frequent complaints in childhood. Although there is evidence that gastrointestinal flora is important in gut motility, there is little evidence that gut flora is abnormal in constipation. Lactobacilli and bifidobacteria increase stool frequency and decrease consistency in normal...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Vandenplas Y,Benninga M

更新日期：2009-04-01 00:00:00

abstract：:To evaluate the prevalence and duration of viremia in relation to the features of liver disease, we investigated hepatitis B virus (HBV) DNA by the polymerase chain reaction in the serum of 39 children with chronic hepatitis B, after hepatitis B e antigen to antibody seroconversion. During a mean observation period of...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Bortolotti F,Wirth S,Crivellaro C,Alberti A,Martine U,de Moliner L

更新日期：1996-04-01 00:00:00

abstract：:The prolonged intestinal retention of a Watson biopsy capsule in a 12-year-old girl with chronic diarrhea is reported. Radiological investigation showed a duodenal obstruction due to superior mesenteric artery syndrome. A preliminary barium study of the upper gastrointestinal tract, before performing blind intestinal ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Bonamico M,Roggini M,Pierro A,Dionisi Vici C,Bitti IM

更新日期：1985-02-01 00:00:00

abstract：:We performed a Japanese nationwide survey of pediatric-onset chronic nonspecific multiple ulcers of the small intestine between January 2000 and July 2013 in 176 institutions of pediatric surgery or pediatric gastroenterology and clarified the clinical features associated with genetic abnormalities in the Solute Carri...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Uchida K,Nakajima A,Ushijima K,Ida S,Seki Y,Kakuta F,Abukawa D,Tsukahara H,Maisawa SI,Inoue M,Araki T,Umeno J,Matsumoto T,Taguchi T

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to obtain objective measures indicative of gastrointestinal maturity using 3 noninvasive technologies. METHODS:Electrogastrography (EGG), abdominal near-infrared spectroscopy (NIRS), and bowel sound/acoustics (AC) monitoring were used simultaneously to obtain physiologic measures of...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ortigoza EB,Cagle J,Chien JH,Oh S,Brown LS,Neu J

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:Zinc (Zn) homeostasis in adults is achieved principally through a balance between intestinal absorption and excretion involving adaptive mechanisms programmed by levels of dietary Zn. Zn absorption in infants is not as tightly regulated as that in adults, which may induce potential toxicity in infants due to...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Jou MY,Philipps AF,Kelleher SL,Lönnerdal B

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:The newborn colon is devoid of microflora, in that bacterial colonization is established after birth. Short chain fatty acids, products of bacterial fermentation, are the major energy source for colonocytes. Because it is not known whether colonocytes in the newborn can metabolize butyrate, this was examined...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Krishnan S,Ramakrishna BS

更新日期：1998-04-01 00:00:00

abstract：:This study was undertaken to determine the effect of reserpine on rat pancreatic growth, to evaluate if reserpine-caused alterations can be prevented by epidermal growth factor (EGF) and/or cerulein treatment, to evaluate the time course of rat pancreas recovery after reserpine, and to determine if EGF and/or cerulein...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Bérubé FL,Benrezzak O,Vanier M,Morisset J

更新日期：1993-07-01 00:00:00

abstract：:We describe a 5-year-old white girl who presented at 18 months of age with an ileal perforation and radiographic evidence of segmental intestinal narrowing. Her initial diagnosis was Crohn's disease; however, on subsequent microscopic review, her lesion consisted of mixed histiocytic and eosinophilic infiltration char...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sutphen JL,Fechner RE

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVES:Dual sofosbuvir/daclatasvir (SOF/DCV) therapy is currently recommended by the European Association for Study of Liver (EASL) as an option for the treatment of chronic hepatitis C virus (HCV) infection in adults for all genotypes; however, it is still not considered for patients younger than 18 years old. We ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Yakoot M,El-Shabrawi MH,AbdElgawad MM,Mahfouz AA,Helmy S,Abdo AM,El-Khayat HR

更新日期：2018-07-01 00:00:00

abstract：:Severity scores are used to predict the outcome of acute pancreatitis (AP). Several scores are used in adult patients, but none has been thoroughly validated for specific use in paediatric patients. We retrospectively collected data from 48 children with AP (13 severe and 35 mild). The main causes were trauma (23%), i...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Fabre A,Petit P,Gaudart J,Mas E,Vial J,Olives JP,Sarles J

更新日期：2012-09-01 00:00:00

abstract：:Calcium absorption from tricalcium phosphate (TCP) was compared to that from calcium chloride, CaCl2, in the presence and absence of carrageenan in the rat model. There was no difference in percent calcium absorption as indicated by femur uptake of TCP or CaCl2 intrinsically labeled with 45Ca given by gavage (78.4 +/-...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Koo J,Weaver CM,Neylan MJ

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVES:Pediatric patients with inflammatory bowel diseases (IBD) require treatment, monitoring, and health maintenance services. We described patterns of primary, specialty, emergency department (ED) and urgent care delivery, and explored patient- and system-related variables that impact ED/urgent care utilization....

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Michel HK,Noll RB,Siripong N,Kim SC

更新日期：2020-07-01 00:00:00

abstract：:We evaluated plasma PIVKA-II (protein induced by vitamin K absence or antagonist-II, acarboxy prothrombin) levels in three infants with hepatoblastoma as a tumor marker. PIVKA-II levels were highly elevated in all three patients. Vitamin K administration, performed in two patients, resulted in only moderate reduction ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Motohara K,Endo F,Matsuda I,Iwamasa T

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:P-glycoprotein (P-gp), the functional product of the multidrug resistance gene (MDR), is a transmembrane protein that extrudes substrates from the intracellular environment. P-gp is expressed on the apical surface of epithelial cells and on cells from the hematopoietic lineage. Human MDR polymorphisms have be...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Staley EM,Dimmitt RA,Schoeb TR,Tanner SM,Lorenz RG

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVES:Intestinal failure-associated liver disease (IFALD) contributes to significant morbidity in pediatric patients with intestinal failure (IF); however, the use of parenteral nutrition (PN) with a fish oil-based intravenous (IV) emulsion (FO) has been associated with biochemical reversal of cholestasis and impr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Khan FA,Fisher JG,Sparks EA,Potemkin A,Duggan C,Raphael BP,Modi BP,Jaksic T

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:The antitumor necrosis factor α (TNFα) antibodies infliximab and adalimumab are effective in inducing and maintaining remission in pediatric patients with Crohn disease (CD). The aim of the study was to evaluate the long-term efficacy and safety of biological therapy in pediatric patients with CD followed at ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Nuti F,Viola F,Civitelli F,Alessandri C,Aloi M,Dilillo A,Del Giudice E,Cucchiara S

更新日期：2014-05-01 00:00:00

abstract：:Twenty children with active ulcerative colitis were assessed before and after 8 weeks of medical therapy with 5-aminosalicylic acid (5-ASA) derivatives and corticosteroids. Local therapy was given for distal disease (seven cases); other disease was treated with oral prednisolone (1-2 mg/kg/day, maximum 40 mg). Eightee...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Beattie RM,Nicholls SW,Domizio P,Williams CB,Walker-Smith JA

更新日期：1996-05-01 00:00:00

abstract：:To assess the effect of chronic administration of amino acids, glucose, and fat on hepatic excretory function, bile flow and bile salt secretion were directly measured in adult rabbits alimented either intravenously or intragastrically. Five groups of animals were studied after 9-11 days on different nutritional regim...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Zahavi I,Shaffer EA,Kelly J,Gall DG

更新日期：1985-10-01 00:00:00

abstract：:Anti-tumor necrosis factor-alpha (TNF-α) blockade is so far the most effective therapy for extensive pediatric Crohn disease (CD), but loss of response is frequently encountered. We describe here the use of golimumab (Simponi) in 6 pediatric CD patients with antibody formation/loss of response to infliximab and adalim...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Merras-Salmio L,Kolho KL

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:Eosinophilic oesophagitis (EE) is a clinical entity characterised by a set of symptoms and eosinophilic infiltration of the oesophageal epithelium. Recent reports indicate that EE is increasingly diagnosed in paediatric patients. We aimed to evaluate the epidemiology of paediatric EE in a European population....

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Dalby K,Nielsen RG,Kruse-Andersen S,Fenger C,Bindslev-Jensen C,Ljungberg S,Larsen K,Walsted AM,Husby S

更新日期：2010-09-01 00:00:00